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Simponi for Ulcerative Colitis User Reviews

Rating: 5.6

Simponi has an average rating of 5.6 out of 10 from a total of 9 reviews for the treatment of ulcerative colitis. 44% of reviewers reported a positive experience, while 44% reported a negative experience.

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  • Bac...
  • Taken for 6 months to 1 year
  • January 22, 2015

"Had a major flare-up back in April that almost led to emergency colonectomy. Hospitalized for 19 days straight, was in 2 different hospitals, lost about half my body's blood and 50 lbs over 6 months' time. 1st doctor put me on many of the wrong medications as the disease was too severe. Starting out on Lialda, Uceris, then up to Remicade, which started to work for about a week, and then Prednisone, which was horrible. When I was in the 2nd hospital, I had another doctor prescribe Simponi, and it took a while, but it's working for sure. I went from 20 times a day of red to 1 - 3 times a day (clear water)."

10 / 10
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41 Report
  • Ohl...
  • Taken for 1 to 2 years
  • May 28, 2015

"Recent colonoscopy confirmed no active inflammation. Experiencing no side effects. Painless self-injector administered every 4 weeks. The only minor difficulties are dealing with the specialty pharmacy and properly disposing of the injectors."

9 / 10
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34 Report
  • Mel...
  • March 18, 2017

"Simponi did not work for me. Tried it three months, and it made all the bleeding, cramping, and diarrhea worse. I really wanted it to work for me, but it didn't. And Janssen was no help, called it 'side effects,' when it was 'exacerbation of symptoms.' Best wishes if you take it, I hope you find success with it. :)"

1 / 10
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20 Report

Frequently asked questions

  • Boo...
  • Taken for 1 to 6 months
  • September 20, 2019

"I have UC, fibromyalgia, RA, diabetes type 2, and many more health issues. I've been on SIMPONI for about 4 months, my symptoms have become worse: chronic pain, intense swelling, burning, tingling hands and feet, bloated stomach that just won't deflate, loss of appetite. I don't want to have the SIMPONI anymore. I'm now worried and scared, as it's rejected my body. I have just about had enough of the intense pain... I'm happy to hear good results from people it has worked for..."

1 / 10
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7 Report
  • Vol...
  • Taken for 1 to 2 years
  • May 27, 2020

"I've got UC, started therapy with Simponi almost two years ago because I was steroid-dependent, even if I generally felt well. The last colonoscopy, done 6 months ago, showed that I was in complete remission, and luckily, I still feel great. I haven't noticed any collateral effect, maybe I've just gained some weight, but probably I was underweight before (I am 1.63m tall, and my actual weight is 51.5kg)."

10 / 10
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6 Report

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  • Kay...
  • Taken for 6 months to 1 year
  • December 23, 2020

"Simponi has been a godsend! Prior to starting Simponi, I was unable to leave my home for any length of time. I had suffered for 2 years with UC and failed other treatments. My last C-scope in November 2020 was the best of the last 4. ❤ If I had one suggestion, it would be to package alcohol swabs with each injection (like Humira does)."

10 / 10
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3 Report
  • Jim...
  • September 24, 2020

"Been on Simponi for 3 months, 5 tubes. I think I'm worse than before. Bloating and going to the toilet more often! I’ll give it another 3 months, but I can tell it's not working. I know someone who also had no success with Simponi, but might with Humira."

1 / 10
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3 Report
  • FHP...
  • Taken for 5 to 10 years
  • September 18, 2021

"Been on Simponi for over 10 years. It has worked miracles with my UC. Full remission. Now I have major joint pain. It started about a year or so ago in my left thumb joint. Now the pain is in every joint except one shoulder, all within the last 8 months. I have no idea what is going on, but the pain from the joints is becoming greater by the day. The docs say age. I'm 62 and no history of RA in the family, but who knows."

7 / 10
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1 Report
  • Ros...
  • Taken for 1 to 6 months
  • December 13, 2020

"Simponi did nothing. Was actually better before I started!"

1 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Ulcerative Colitis

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Symptoms and treatments