Simponi Aria and Fatigue: What Users Say

• Len...
• Taken for 1 to 2 years
• May 7, 2018

For Rheumatoid Arthritis "I have taken just about all the meds you can think of. Some are better than others, but after a while, too many symptoms come up. My latest Simponi seemed great in the beginning, but as others stated, I was tired all the time. Contracted pneumonia, edema in the ankles, and 3 UTIs in 6 months. So I am going to go off. I think it suppressed my immune system so much I was sick all the time. Not sure if I will try Humira, which others are taking and seem to be okay with it."

• Sfs...
• June 27, 2016

For Rheumatoid Arthritis "I was diagnosed with seropositive RA nearly 35 years ago and have been on just about every NSAID, DMARD, infusion, and combinations of these. Simponi Aria, along with leflunomide, is my current cocktail. While it seems to be keeping my joint pain under control, my fatigue is off the charts, and I have lots of body aches, frequent headaches, and gastrointestinal problems. My blood pressure and glucose levels are also elevated, though I'm not sure if this is due to this medication or not."

• Emm...
• Taken for 1 to 6 months
• July 10, 2018

For Psoriatic Arthritis "No pain or skin issues after 3 days, but about 2 weeks after the first injection, I got sick for the 1st time. The fatigue set in at week 3. I was well again at week 4, right in time for my next dose. Once again, by week 3, I was sick with the worst throat/adenoid infection that just wouldn't quit. The fatigue is life-changing. Dr. took me off after my second throat infection in 6 weeks."

• Ksi...
• Taken for 1 to 6 months
• July 28, 2022

"I am actually on this for Pustular Psoriasis. I can't get over the extreme exhaustion, head and chest congestion, headaches, muscle aches, constant stuffy but running nose. My psoriasis is worse. It feels like it is constantly on fire, the blisters only go away for like two weeks, then come back worse than they were. Sweating a lot, and my heart takes spells of racing but goes away after 5 or 10 minutes. It will even happen in the middle of the night. It gets so bad it wakes me up from sleep. I itch now from head to toe, and now just about everything that touches my skin gives me welts. My vision has suddenly gone bad. I understand I’m old, but this is crazy. It’s not worth the expense and getting much worse for 2 weeks of being without the blisters."

• Han...
• Taken for 6 months to 1 year
• August 19, 2019

For Psoriatic Arthritis "I’ve been on Simponi Aria infusions. They have helped with pain and stiffness for approx. 4 weeks. I take prednisone for breakthrough pain. Sometimes I sleep for 72 hrs because of fatigue. Have had to add another HBP Rx! Praying for strength to discontinue."

• 7Do...
• Taken for 6 months to 1 year
• February 19, 2023

For Rheumatoid Arthritis "I was on Simponi Aria for almost a year. At first, it worked great. Helped my fatigue some. Then, about the last 3 infusions, after about a month, I could tell it was wearing off. So now, they are switching me to something else."