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Fluticasone / salmeterol and Anxiety: What Users Say

Brand names: Advair Diskus, Wixela Inhub, Advair HFA, AirDuo Respiclick

Anxiety: mentioned by 6 users (2.2%)

Based on user experiences from 274 Fluticasone / salmeterol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

shortness of breath 14.6%
cough 11.3%
sore throat 8.8%
chest pain 5.5%
headaches 5.5%
thrush 5.1%
increased heart rate 4.0%
mucus 2.6%
anxiety 2.2%
dizziness 2.2%

Reviews for Fluticasone / salmeterol

Commonly mentioned side effects
  • Moo...
  • Taken for less than 1 month
  • May 26, 2020

Wixela Inhub (fluticasone / salmeterol) for Asthma, Maintenance "Inhub dispenser is awkward. Don't feel like I get the same dosage as Advair. Makes me tired, post-nasal drip, and on-and-off cough. Makes me anxious that I'm not getting enough med and fear an attack. Don't want to get sick, especially with Covid-19 about. I'd rather have Advair HFA."

2 / 10
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41 Report
  • lad...
  • Taken for less than 1 month
  • November 14, 2019

Advair Diskus (fluticasone / salmeterol) for Asthma, Maintenance "I'm a 48 years old - never had asthma. Multiple respiratory infections left me wheezing daily. Doc prescribed Albuterol plus Advair. I was scared to start meds and didn't for a few weeks. Wheezing got bad enough I went back to doc, talked about concerns, and they explained the importance of use. I started it in the office 3 weeks ago - I feel so much better now. I didn't realize how bad my breathing was. I haven't needed the Albuterol since. (knocking on wood!) Side effects for me = nervousness for ~ hour after use; intermittent mild throat irritation; increased # of heart palpitations (have had for years). I wish I would have started it sooner."

9 / 10
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19 Report
  • Brk...
  • Taken for less than 1 month
  • June 5, 2021

Wixela Inhub (fluticasone / salmeterol) for Asthma, Maintenance "I’ve only been on this inhaler for a week, and I had to stop immediately. It makes me extremely jittery - I feel like I’ve consumed 1000 cokes and coffees. It also gave me muscle spasms in my fingers and made my voice extremely hoarse. That being said, I do feel like my breathing got better, but I cannot deal with the side effects at all. I’ve since switched to another inhaler. Hopefully, that will work out better for me."

2 / 10
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12 Report

Frequently asked questions

  • Ven...
  • Taken for 1 to 6 months
  • July 17, 2021

Advair Diskus (fluticasone / salmeterol) for COPD, Maintenance "I started taking this medicine for a COVID cough. After one week of taking it, I started having body aches. Another week passed, and I was having chest pressure. It did help with the cough, but then I started having heartburn and was coughing more than when I had COVID. I started to develop gastrointestinal issues. After eating, I would belch, and regurgitation would happen. Heartburn and chest pain were also common. A cough would happen after eating. I went to see a pulmonologist, and she told me that I can just stop taking it and that no withdrawal symptoms would happen. That was a lie. After stopping it, cold turkey, I started feeling like absolute rubbish. I started to have diarrhea, abdominal pain, insomnia, anxiety, depression, feeling dizzy and faint-like. She never told me about adrenal insufficiency that could happen after stopping a corticosteroid. It’s been almost 3 months since I stopped the medication, and I feel like the symptoms are only getting worse."

1 / 10
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  • Cab...
  • Taken for 10 years or more
  • October 24, 2016

Advair Diskus (fluticasone / salmeterol) for Asthma, Maintenance "Advair is effective in treating my asthma. Unfortunately, I often feel restless, agitated, and maybe anxious. I'm thinking of getting off of the drug, but am afraid my asthma will get worse. I'll probably try gradually weaning off and have an emergency inhaler nearby. I'm just growing tired of the side effects. I may also look into another drug if my asthma gets worse after quitting Advair."

7 / 10
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  • Kri...
  • August 10, 2021

Wixela Inhub (fluticasone / salmeterol) for Asthma, Maintenance "Newly diagnosed with allergic asthma; I have no other meds to compare this to. That being said, I can safely say Wixela sucked. I only used it 3 times and quit. I got a strange tight sensation in my forehead after using it, but didn't link it to the med. The 3rd time I used the med, I started to get a burning sensation in my face that wouldn't go away, and I felt woozy and anxious. I woke up the next day with tingling skin and a couple of welts on my legs and ankles. I decided to never take the med again and stick to albuterol until the symptoms went away. I noticed the same sensations would come back every time I used a prescription fluticasone nasal spray, which I used to tolerate before this. I can't really recommend Wixela, even for someone who doesn't have Advair to compare it to. The way you breathe it in makes it hard to tell if you're getting a full dose or not. The powder seems too thick. The only pro is that I didn't use albuterol for those two days."

1 / 10
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3 Report

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