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Fluticasone / salmeterol for Asthma, Maintenance User Reviews (Page 3)

Brand names: Advair Diskus, Wixela Inhub, Advair HFA, AirDuo Respiclick

Fluticasone / salmeterol has an average rating of 4.5 out of 10 from a total of 207 reviews for the treatment of Asthma, Maintenance. 37% of reviewers reported a positive experience, while 55% reported a negative experience.

Reviews for Fluticasone / salmeterol

  • Thumber
  • Taken for less than 1 month
  • November 30, 2015

Advair Diskus (fluticasone / salmeterol) "Was prescribed Advair two weeks ago and haven't used Albuterol inhaler since. I notice easier breathing immediately and had absolutely no side affects. I don't even taste it but always rinse anyway. Before using Advair, I was using the inhaler about 10 times a day and still was out of breath when I tied my boots. After two days on Advair, I was able to attend a Packers game and walked about a mile to the stadium and another 60 flights of stairs to get to our seats. I would have been dead the week before. I'm hoping I can continue using this medication without getting any side affects. I have my life back and want to keep it that way."

10 / 10
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29 Report
  • SKBW
  • Taken for less than 1 month
  • February 20, 2013

Advair Diskus (fluticasone / salmeterol) "Prescribed Advair Diskus (250/50) twice a day. My blood pressure was 130/80 when I started medicine, which is about the highest if has ever been. I was not suppose to go back to the doctor for 30 days. But luckily last night I had my blood pressure checked, it was 151/98-I was shocked! I have only been on the medicine 15 days. Advair probably helped me through my upper respiratory problems, but I think I should have been warned about this side effect."

4 / 10
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35 Report
  • lady...
  • Taken for less than 1 month
  • November 14, 2019

Advair Diskus (fluticasone / salmeterol) "I'm a 48 years old - never had asthma. Multiple respiratory infections left me wheezing daily. Doc prescribed Albuterol plus Advair. I was scared to start meds and didn't for a few weeks. Wheezing got bad enough I went back to doc., talked about concerns, and they explained importance of use. I started it in the office 3 weeks ago- I feel so much better now. I didn't realize how bad my breathing was. I haven't needed the Albuterol since. (knocking on wood!) Side effects for me= nervousness for ~hour after use; intermittent mild throat irritation; increased # of heart palpitations (have had for years). I wish I would have started it sooner."

9 / 10
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18 Report

Frequently asked questions

  • erin
  • July 8, 2014

Advair Diskus (fluticasone / salmeterol) "I was prescribed this inhaler for my asthma and I found it did a good job of bringing my breathing back to normal. However, I also experienced numerous side effects from the medicine such as very painful leg cramps/spasms that kept me from sleep and at times work/school and recurrent bacterial sinus infections (ie. Facial/ear pain, ringing in ears, headache) which I had never had prior to using Advair. I also had a sore throat at times while on this medication which to me is very minor and I would have continued use if this was the only side effect. Although it was not a good fit for me I would recommend this medicine to others who are struggling to control their asthma."

8 / 10
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31 Report
  • Dooley
  • Taken for 1 to 6 months
  • April 17, 2021

Wixela Inhub (fluticasone / salmeterol) "Using Wixela 500 for 4 months. Inferior product - shocking that it passed FDA. Mechanism is terribly awkward - difficult to open and hold while pressing down on "release" handle, particularly with arthritic hands and fingers. Should be redesigned or taken off market. Not even close in comparison to Advair."

4 / 10
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13 Report

Are you taking this medicine?

  • Mrs...
  • April 8, 2013

Advair Diskus (fluticasone / salmeterol) "Been on 250/50 Advair for just over a year. It does great at preventing asthma attacks. I still have congestion & coughing. Despite rinsing my mouth & brushing my teeth after use of Advair, my voice has become quite hoarse within the last 2 weeks. I'm thinking of switching back to Symbicort. I took Asmanex before taking Symbicort but it wasn't sufficient to control my asthma."

8 / 10
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33 Report
  • Sageg...
  • Taken for 10 years or more
  • September 5, 2016

Advair Diskus (fluticasone / salmeterol) "Asthma since 26, year round allergies, Advair and montelukast for years. Feel i'm alive in my 70s because of some smart, caring Doctors. Biggest problems--no generic and super expensive now that prices have been raised. Donut hole every Year! Used to be more reasonable. Not advised to change since Advair and monte work. But can't afford to use 2 times a day as doctor recommends. I think it is Mylan also that raised prices out of seniors reach. Please help bring price down again. Thanks. Insurance covers part reasonably than too high in donut hole."

9 / 10
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25 Report
  • Wendy
  • Taken for less than 1 month
  • July 23, 2021

Wixela Inhub (fluticasone / salmeterol) "I ended up going to the ER after taking my first dose due to an adverse reaction. I had trouble swallowing, felt short of breath, tightness in my chest , face flushed, fast heart rate, and numbness and tingling in my fingers."

1 / 10
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12 Report
  • VLN
  • Taken for 10 years or more
  • March 5, 2015

Advair Diskus (fluticasone / salmeterol) "I had been on Advair for ten years and enjoyed not having asthma attacks, being able to exercise without using a rescue inhaler all of the time. Unfortunately due to the cost of Advair my insurance has dropped it from the list of medications they will cover and I have been switched to another brand. The new one does not work as well."

10 / 10
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28 Report
  • Anonymous
  • Taken for 1 to 6 months
  • April 21, 2021

Wixela Inhub (fluticasone / salmeterol) "I have COPD and asthma. Wixela makes me cough, when you can't breath well trying to breath in powder is ridiculous, it does not work as well as my Advair hfa did, walking to the mail box maybe 60 feet I shouldn't have to use my rescue inhaler"

2 / 10
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12 Report
  • AJano
  • Taken for less than 1 month
  • February 28, 2021

Wixela Inhub (fluticasone / salmeterol) "I was on Breo for about 3 years and was breathing normally. I never had to use my albuterol inhaler. At the beginning of the year the price of Breo skyrocketed for me so I decided to try Wixela. It never worked. It started with a sore throat (I am very careful to rinse my mouth and spit out the water after each use.) After a few days the coughing started. I tolerated that only because it was a weekend and I couldn’t call my doctor. I am going back to Breo, I’m so angry that this drug was approved. My scenario was mild compared to what others are going through. Scary stuff."

1 / 10
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  • Anonymous
  • Taken for 10 years or more
  • July 17, 2019

Advair Diskus (fluticasone / salmeterol) "I have suffered with asthma my entire life so I am familiar with many drugs used to treat this disease. Advair was prescribed to me 30 years ago and I have loved it from the beginning. I no longer had to suffer with the jitters and hyper behavior, like ALL of my prior medications. I take this daily/as prescribed and have no complaints or awful side effects. Sometimes my breath smells bad as a result but I can breathe so I can't really complain. Thank you-now if only I could get my insurance provider to cover it."

9 / 10
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16 Report
  • Ell...
  • March 3, 2010

Advair Diskus (fluticasone / salmeterol) "I have been using Advair for about 5 years. When I first noticed my wheezing and coughing, I thought I had a cold, But the doctor said it is bronchial asthma. He started with Prednisone and Advair. I soon felt better I stopped the Prednisone and I am on Advair 250/50 since. Recently I was advised to see a Chiropractor he promised to help take me off all medications and I will be okay. What a mistake? In order for him to do this I had to stop my Advair, because he said he can't fight with it, I must first stop taking it. The end result was that I spent about $400.00 for twice a week visits. I saw no results on the contrary my wheezing came back full force with the tightness of my chest I had to start all over again with the medications."

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  • asthm...
  • Taken for 1 to 2 years
  • October 18, 2021

Wixela Inhub (fluticasone / salmeterol) "Wixela is AWFUL. Like many other folks here, my asthma was well controlled with another medication - in my case, a very low-dose Advair. When my insurance forced me to switch to Wixela, it didn't work at all. My doctor increased dosage a couple of times, and still no relief. In these days of Covid, every time I cough, which is all day long, people around me look terrified. (I've tested negative for Covid many times. This is just my asthma.) Why is this Wixela garbage even still on the market? I'd give it a zero-rating if that were an option. IT DOES NOT WORK."

1 / 10
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10 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 2, 2022

Wixela Inhub (fluticasone / salmeterol) "Previously shared my experience with Wixela on 1 Oct 2022 and wanted to share this update to help others. Had been using Advair for 23 years and then I was switched to Wixela which had orrible side effects. Although it is therapeutically equivalent to Advair Diskus, I discovered that it was the FILLERS used in Wixela that I had a bad allergic reaction to, which actually induced asthma (among other things). I had reported my experience with Wixela to the FDA...they did contact me and I then gave them an update about the FILLERS as being the culprit. Tricare/Express Scripts did originally deny a prior authorization for Advair as prescribed, no generic; however, my doctor's office kept up the fight and finally gained approval. I now have my Advair back and am doing well and I have prior authorization approved for a lifetime."

1 / 10
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7 Report
  • Brkly...
  • Taken for less than 1 month
  • June 5, 2021

Wixela Inhub (fluticasone / salmeterol) "I’ve only been on this inhaler for a week and I had to stop immediately. It makes me extremely jittery - I feel like I’ve consumed 1000 cokes snd coffees. It also gave me muscle spasms in my fingers and made my voice extremely hoarse. That being said, I do feel like my breathing got better but I cannot deal with the side effects at all. I’ve since switched to another inhaler. Hopefully, that will work out better for me."

2 / 10
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11 Report
  • THE...
  • Taken for 5 to 10 years
  • February 11, 2015

Advair Diskus (fluticasone / salmeterol) "This medicine changed, on a fundamental level, my quality of life. I went from nearly always being out of breath due to asthma to practically never needing a rescue inhaler. It made my asthma vanish."

10 / 10
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25 Report
  • Anonymous
  • Taken for 1 to 6 months
  • July 3, 2022

Wixela Inhub (fluticasone / salmeterol) "Please read this. I used Advair for years then the pharmacy substituted Wixela. It did nothing. Went back on Advair and it was great. Then the doctor asked if I could try the generic made by Prasco. It was very good and have used it for a couple years now. Turned out it’s Advairs own generic. Give it a try. I have been very happy with it. It even comes in the same dispenser as Advair. I don’t know what the deal is Wixela because it’s supposed to be the same medication but I agree with what I’ve read here. It has a problem!"

1 / 10
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8 Report
  • Shar
  • Taken for less than 1 month
  • April 4, 2021

Wixela Inhub (fluticasone / salmeterol) "Due to my insurance not wanting to pay for the Advair I’ve been taking for years, I was given Wixela. With Advair, It worked perfectly. With Wixela I couldn’t walk to my kitchen without being out of breath. I had such a hard time going up a flight of stairs. It didn’t control my COPD at all. I couldn’t function at work and everyone could hear me breathe. On Advair, no one could suspect I had any breathing issues. Scientifically, it should work, clinically, it did not. Thankfully My Pulmonologist reached out to my insurance company and I was given Advair again. Wish it worked, it is cheaper."

1 / 10
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11 Report
  • MLU
  • December 5, 2016

Advair Diskus (fluticasone / salmeterol) "Was using Pulmicort for years for asthma maintenance; I found it made a difference but would stop working for periods of time. I asked my physician to switch me to something else and she put me on this. A marked difference. This has a steroid as well as a stimulant (to open your lungs upon inhalation, much like a rescue inhaler, which Pulmicort did not have). I forgot to refill my Advair this month (I mail order three months at a time with my insurance, WAY cheaper) and have been without for about 4 days. I can definitely tell the difference. My rescue inhaler use has gone up, and subsequently goes way down (to almost nonexistent) when I'm on Advair. Highly recommended."

9 / 10
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20 Report
  • Nervous...
  • April 30, 2016

Advair Diskus (fluticasone / salmeterol) "I had told my Dr. How when I walk up my stairs in my house how I'm out off breathe and how my chest had been feeling tight over the last few months and I just use my nebulizer or my ventolin pump and it helps me feel better .But then she suggested Advair Diskus and within the 2nd day I felt the tightness in my chest like I was having an asthma attack and then my throat started to feel swollen so I stopped the medicine . Since using this medication my throat is sore, swollen glands,hurts when I swallow . I'm very nervous and will not use it anymore"

1 / 10
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21 Report
  • Barblee
  • September 2, 2017

AirDuo Respiclick (fluticasone / salmeterol) "This medication has helped my cough, made breathing easier and decreased mucus tremendously, however I did have side affects, blurred vision, confusion, numbness in legs, dizziness, nausea and sore throat."

9 / 10
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18 Report
  • Alano
  • Taken for 1 to 6 months
  • February 4, 2019

Advair HFA (fluticasone / salmeterol) "Did not improve my breathing at all. It actually worsened my condition. In addition my vision was damaged, my inner ears and head are under constant pressure. I have stopped the advair but I am still experiencing the negative effects."

1 / 10
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15 Report
  • Life...
  • Taken for 2 to 5 years
  • May 14, 2020

Advair Diskus (fluticasone / salmeterol) "I’ve been using advair for 5 years works great for asthma first time asthma felt controlled but side effects of a tight throat and change in voice is concerning. Now I had to stop this medicine as throat issues have become worse the occasional sore throat is now at least once a week and my throat feels like it’s working so hard like the muscles in the neck are actually sore from the tightness. Not really sure what is happening and not sure what to do with an asthma prevention alternative now. Also had a major asthma attack and took about a month to recover so if your throat starts feeling funny and you voice box and larynx feels sore beware and talk to your doctor it just came on so fast"

7 / 10
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12 Report
  • Barely...
  • Taken for 1 to 6 months
  • April 11, 2023

Wixela Inhub (fluticasone / salmeterol) "Wixela has been a waking nightmare for me! I can't breathe, I can't sleep, non-stop profuse coughing to the point of aching ribs and sore lungs. The sleepless nights are the worst. The huge bags under my eyes tell it all! No energy, loss of appetite, irritability. You name it, I've got it. I wasn't surprised to see the horrible reviews that confirmed all I've been feeling. The Wixela mechanism itself is a joke. If I didn't know better I would think they were just practicing on people for some low level chemical warfare! Lord help us!"

1 / 10
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5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.