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Prozac for Major Depressive Disorder User Reviews (Page 4)

Prozac has an average rating of 6.4 out of 10 from a total of 91 reviews for the treatment of Major Depressive Disorder. 54% of reviewers reported a positive experience, while 30% reported a negative experience.

Reviews for Prozac

  • enska
  • Taken for less than 1 month
  • November 15, 2021

"I've only been taking Prozac for a week, but I'm really cautiously optimistic and today I feel pretty good. I haven't been able to say that for a long time. I took it almost 20 years ago for a time but didn't like it. I decided to try it again because I'm increasingly having treatment-resistant depression. I have tried MANY antidepressants. Some don't affect me at all and some give me extreme muscle spasms. But this doesn't seem to have any bad side effects. Again, cautiously optimistic!"

8 / 10
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  • Alan...
  • Taken for 6 months to 1 year
  • May 19, 2017

"I'm still trying to find a medication that works for me. But this is one that the doctor prescribed me about two years ago, and I took it for very close to a year. It did not help. They kept adding more dosage until finally I quit seeing my psychiatrist altogether and stopped taking the medication."

2 / 10
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  • stevie
  • Taken for 1 to 6 months
  • July 21, 2022

"SIGH. Yet another antidepressant that made me worse than ever before. I sleep all day and have no motivation or pleasure (anhedonia), so thought after 9 years I'd finally try Prozac. 20mg. Nope. It made me extra irritable from the beginning, made me hyper and HUGELY socially anxious and with a huge excess of nervous energy. My OCD motor tics worsened due to the extra nerves, as did my "self soothing" behaviour of skin picking and biting the inside of my mouth. My stutter also returned after being much improved over the last few years. I endured all this for almost 8 weeks, to give it time to really work. Finally, it stopped me sleeping. I've always had insomnia but take an antihistamine to sleep, which has worked for 5 years. This stopped it working and I had to stop taking the Prozac. It took a month to be able to sleep ok again. It DID give me more energy, but nowhere to channel it as I still had no interest in anything."

2 / 10
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3 Report

Frequently asked questions

  • Anonymous
  • February 10, 2022

"It worked the first year taking two 20mg tabs at night and then one 20mg tab at lunch then I developed a routine where I couldn't sleep at night so we had to change it to two 20mg tablets in morning and one at dinner after about 6 months I started sleeping in the day time and was able to sleep thru the night also. So I was sleeping about 17 hours a day after three weeks I called Dr. And we made a switch and been switching about every two months next visit I'm going to see if we can't try the Prozac at a lower dose maybe 20mg twice a day"

8 / 10
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  • A...
  • Taken for 1 to 6 months
  • November 25, 2022

"This review is about how prozac worked for my teen. He started on 10mg prozac to treat depression. My husband and son and myself were nervous because we do not use a lot of medications. The 10 mg prozac worked quite well for him for a couple of months and we could tell a positive difference in his mood in less than a week after beginning to take it. He did have some mild digestive side effects. Eventually his dr moved him up to 20 mg prozac and the digestive side effects became worse, so he went back to 10mg but the digestive side effects continued and he eventually quit taking prozac because his stomach was bothering him too much—diarrhea, gas, and nausea. His depression returned in a month, so he restarted prozac, his mood improved and his stomach troubles returned. His dr next suggested lexapro. It took several weeks for the lexapro to help his mood, and when it finally started working, the digestive issues began again, so he weaned off."

8 / 10
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Are you taking this medicine?

  • theon...
  • Taken for 6 months to 1 year
  • November 3, 2022

"It is hard to say how effective Prozac was in my experience. There definitely were periods of time in which I had a higher mood than normal, but there was also a consistent feeling of numbness (which some refer to as Emotional Blunting). At least for me, since it didn't really help and just brought the feelings of numbness, I can't say that I don't like it but I definitely don't love it."

3 / 10
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  • Queen...
  • Taken for less than 1 month
  • March 8, 2021

"I have been on Prozac for 3 days. And last night I started having chest pain’s and I couldn’t breath . I try to eat but I get nauseous and not hungry . I called my doctor to find out if it’s normal. And I have been feeling anxious. Hope he calls me back ."

3 / 10
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1 Report

More FAQ

  • Decker
  • Taken for less than 1 month
  • June 12, 2022

"I started with 10 mg of Prozac 3 weeks ago. I also suffer from fibromyalgia as well as neck and back issues for several years. I have been on hydrocodone for the last 4 years. For some reason my pain medication is no longer working since I started Prozac. From what I have read this is common and should be taking oxycodone. Anyone with chronic pain and take pain medication knows that taking oxycodone is taboo. I really want to stick with the Prozac after starting 20mg next week. I am hoping it will work after the increase in the next month. It probably has a lot to do with the fibromyalgia that the Prozac is taking longer to work for me. I'm just hoping that it will work in another month. I do believe my doctor will write me a prescription for the oxycodone and give it a month to see if the Prozac kicks in. If it does not, I will have to go back to the Celexa and hydrocodone I've been on that no longer works. Not sure how I can't get a response. I have not noticed any on this site."

3 / 10
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  • wer
  • October 24, 2014

"The best SSRI, beats depression, anxiety, and obsessive-compulsive disorder."

10 / 10
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64 Report
  • Siege
  • Taken for 2 to 5 years
  • October 19, 2020

"It made me numb. It never helped with depression, just made me never happy or smile genuinely."

1 / 10
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27 Report
  • Anonymous
  • Taken for 10 years or more
  • September 12, 2020

"A life saving medication for many years"

9 / 10
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19 Report
  • minny...
  • Taken for 10 years or more
  • May 15, 2014

"Excellent for Major Depressive Disorder, as well as some mixed anxiety disorders."

10 / 10
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37 Report
  • JFK
  • Taken for 6 months to 1 year
  • August 8, 2019

"I take 80mg of Prozac with Lamictal, and it helps a lot. But be warned, it will ruin your sex life."

9 / 10
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20 Report
  • Tomnik
  • Taken for less than 1 month
  • March 20, 2019

".Prozac is wonderful, but because of some sexual side effects I can't give 10."

8 / 10
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17 Report
  • Tony
  • Taken for 1 to 6 months
  • July 10, 2019

"Prozac 80mg, Lamictal 200mg, & Klonopin 2mg are a great combination for my MDD. Works Great!!"

9 / 10
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13 Report
  • Coco
  • Taken for 1 to 2 years
  • April 15, 2020

"Didn't give zombie affect like Zoloft, still made sex bad and ED strong"

1 / 10
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11 Report
  • Nikdick
  • January 4, 2017

"Good experience with prozac"

8 / 10
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16 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 17, 2020

"This drug made me so much worse. It give me bad side effects and made me even more suicidal. Not for me!"

1 / 10
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10 Report
  • ColRa...
  • Taken for 1 to 6 months
  • March 6, 2015

"Helped control Anger issue but after 90 days and two increases in doseage the Depression is unchanged"

3 / 10
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18 Report
  • Just...
  • Taken for less than 1 month
  • August 20, 2015

"Im just taking this med starting today....be back in 2 weeks to tell yall how I feel!"

8 / 10
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16 Report
  • Melissa
  • Taken for 6 months to 1 year
  • January 3, 2022

"This drug is weak and does not help with depression."

1 / 10
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6 Report
  • BeeRe...
  • Taken for 1 to 6 months
  • December 16, 2020

"Prozac made me more suicidal and I isolated myself more. Glad I am off of it."

3 / 10
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7 Report
  • kon
  • Taken for less than 1 month
  • January 16, 2023

"Prozac worked for me within a few days. My social anxiety significantly decreased and I possibly have better focus. I have had a weird heart rhythm or stinging but well worth it."

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  • CallM...
  • January 20, 2022

"I've just gotten on 40mg of prozac and it is working like a charm. I is like before I used to feel so tired and now I feel more awake."

9 / 10
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2 Report
  • Mark
  • Taken for 1 to 6 months
  • September 8, 2021

"It just made me feel numb which personally I didn't like"

4 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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