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Fluorouracil topical for Actinic Keratosis User Reviews (Page 5)

Brand names: Efudex, Tolak, Carac, Fluoroplex, Efudex Occlusion Pack

Fluorouracil topical has an average rating of 7.3 out of 10 from a total of 103 reviews for the treatment of Actinic Keratosis. 63% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Fluorouracil topical

  • My...
  • Taken for less than 1 month
  • September 22, 2021

"I started with the fluorouracil cream on Sunday afternoon. I washed my face with water and put it on again at night. I felt really tired and sick on Monday so I stayed in bed but applied it again as directed. By Tuesday I couldn’t stand it anymore and washed it off and didn’t apply it again. It’s Wednesday and my face is tight and burning and my eyes hurt and I have a headache. To me, the pain and feeling sick and tired isn’t worth it. The VA has scheduled me an appointment to have cryotherapy and I’m okay with that. I will never use this stuff again and I give anyone who can do it for an extended period of time a bravo soul!"

2 / 10
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  • Chuck
  • February 19, 2021

"Last year I treated my scalp (twice daily x 21 days). This year I'm treating my scalp, face, ears, neck, upper back and shoulders X 21 days, healing for 3 weeks, and then retreating for X 21 days. I've just finished my 4th week of active treatment. My scalp's healthier this year. Last year it was one solid red scabby crusty cap. This year it was only red and scabby in tiny spots the first 21 days, and has only been red in a few spots this past week. This has been my first time treating my face, ears, neck, upper back, and shoulders, and they looked like my scalp did last year during the first 21 days. They're only red in patches these past 7 days. The experience has not been fun, but not awful, and very well worth it to me. I've had previous MOHs and regular surgeries to remove squamous and basal cell cancers, and have had melanoma spots (plus their area lymph nodes) surgically removed. The Sun has not been my friend. I think being mentally prepared to accept the process helped."

10 / 10
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3 Report
  • I...
  • Taken for less than 1 month
  • July 30, 2022

Tolak (fluorouracil) "Using Tolak for 3 weeks , I have red spots almost bloody looking , it does get little crusty and at every time I shower the crust falls off and I wait another day to dry out , I keep you posted about the outcome Ani"

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2 Report
  • Forest...
  • December 5, 2020

"I've had a "remarkable" reaction to this fluorouracil cream. It burned through multi-layers of skin in the center of my face - and like a "T" across my forehead. Once I stopped using the cream, I tried several things to relieve the pain I was still having due to the peeling. Without question, the "Bacitraycin Plus" (with pain relief) (in the RED package) is the best of all. It has a topical analgesic in it, called "Pramoxine HCl". The manufacturer used to include Lidocaine, but have discontinued that in favor of Pramoxine. I now apply it to all of the affected area in small circles gently - and the give it about 3 minutes to fully work. You'll need to apply it about every four hours - while awake - as newer, drier, flakier skin surfaces."

10 / 10
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3 Report
  • John
  • Taken for less than 1 month
  • September 14, 2023

"The treatment is a little rough during the 2nd and 3rd weeks, but it is very effective and well worth it. I am 59 and did the treatment for 21 days, two times per day, on the forehead, temples, cheeks, nose, and ears. The first week, it just felt like having a sunburn. I am retired, but if I were still working, I would work during the first week. During the 2nd and 3rd weeks, my face felt raw, and it was painful to clean my face, dry it, and then put on the cream. It is tolerable though, and once the cream was on, I felt relief. My face looked tore up, but I still went out in public. I read that Fluorouracil is deadly for dogs. Don't let your pet get ahold of the tube or lick the treated area. It took several days following the treatment to start feeling better. I used Aquaphor and some of my wife's moisturizers. To quote a guy on YouTube going through the same thing, there are some things in life that you can't go around, you have to go through. Just do it!"

10 / 10
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  • B Hay...
  • Taken for less than 1 month
  • November 5, 2021

"I’m in day 6 of recovering from 14 days of 2x per day treatment of my full face-forehead, cheeks, nose, chin and around lips. I’m a light-skinned scotch-Irish complexion who has spent many summers near the equator on 4 continents and 4 years in Siberia winters. The whole face lit up like a Christmas tree at about day 6 and then at day 8 or 9 with little blisters and sores that turned to scales over a lot of my forehead, cheeks and chin. The last 3 days of applying Efudex were torture. I did this treatment in 2006 so knew ahead of time that it would be rough but now at age 68 the reaction was more widespread and intense. The worst were blisters on my lips. I used Tylenol during the day and hydrocodone on the worst nights for pain and applied aquaphour salve during treatment and now using aloe Vera gel with itching and peeling. I have also taken Benadryl to help with itching and last night was able to sleep several hours. If doing this again, I do parts of face at a time."

10 / 10
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  • Susie
  • December 6, 2022

"Used Efudix 5% cream on solar keratosis of the upper lip. The dermatologist prescribed it for two weeks, warning of a 'cold sore-like' localized reaction. On day 10 my upper and lower lips blistered badly, where the cream had not been applied. Very painful, but I persisted with the treatment until the end. Warm salty water applied regularly relieved some of the pain. At night I slathered my lips with Ungvita Vitamin A cream, then a thick cream for nappy (diaper) rash cream on top. Both lips were blistered, cracked, and bleeding. They're healing now, and I hope the keratosis is gone."

8 / 10
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  • Apoc-...
  • Taken for less than 1 month
  • July 4, 2023

"71-year-old healthy patient has been prescribed Apoc-5fu to prevent future cancerous development on the nose. After 4 days, experienced a rash and pruritus on the back, stomach, wrists, arms, calves, which led to the early termination of the treatment. Now on Prednefrin Forte to combat the constant itching."

1 / 10
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  • Anonymous
  • May 4, 2018

Efudex (fluorouracil) "I work for a dermatologist. In order for Efudex to react, sun damage/AK's, cancer should be present. Undamaged skin will not react to Efudex."

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110 Report
  • Deewi...
  • Taken for less than 1 month
  • September 17, 2017

Efudex (fluorouracil) "I have a question, not comment, please. I'm on day 6 of 14 days of application. No reaction. Is this normal? I'm applying a thin layer 2 times a day. Am I doing something wrong or is this normal?"

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87 Report
  • Lee
  • Taken for less than 1 month
  • May 3, 2020

Efudex (fluorouracil) "I just started I’m on day three I am absolutely terrified "

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25 Report
  • Sahar
  • Taken for less than 1 month
  • July 29, 2016

Tolak (fluorouracil) "I have used this cream for 5 days for pre-cancerous spots. Nothing is happening so far."

1 / 10
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26 Report
  • Why
  • June 14, 2018

Carac (fluorouracil) "Why priced out of the average persons cost? Really worked great for my skin condition. Now I can’t afford it. Greedy people"

1 / 10
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18 Report
  • Char...
  • June 2, 2017

"Given Rx due to pre-cancerous spot on side of face. So far, I have had no side effects. I am day 11 of 14 day treatment. No redness, no peeling."

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16 Report
  • Goat
  • October 31, 2016

"Worked fine in two weeks of 2x per day application in my bald head. However some AKs returned. Starting treatments again."

7 / 10
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9 Report
  • george
  • Taken for less than 1 month
  • December 25, 2021

"The nasty side effects of Flourouracil can be alleviated by using Lidocaine cream or gel but better the spray on liquid formulation"

10 / 10
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  • T T
  • February 26, 2018

Carac (fluorouracil) "Overrated and overpriced. Won't buy again at any price."

2 / 10
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3 Report
  • Jakes...
  • Taken for less than 1 month
  • April 30, 2017

"I used it once a day for 13 days and took two days off, I'm wondering if it's ok to start again or not. I was supposed to go 4 weeks. Anyone have any comments?"

9 / 10
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3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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