Skip to main content

Fexofenadine / pseudoephedrine User Reviews & Ratings

Brand names: Allegra-D 24 Hour, Allegra-D 12 Hour, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 24 Hour Allergy & Congestion

Fexofenadine / pseudoephedrine has an average rating of 6.7 out of 10 from a total of 64 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 25% reported a negative experience.

Condition Avg. Rating Reviews Compare
Allergic Rhinitis
6.7
 60 reviews for Allergic Rhinitis 899 medications

Write a review

Reviews for Fexofenadine / pseudoephedrine

Commonly mentioned side effects
  • Ste...
  • May 13, 2015

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This medication is NOT recommended! I have severe allergies to the spring weather, and since nothing else was working for me, I decided to try this. At first, it was like magic, my allergies went away, no itchy eyes, no sore throat, I felt great! The side effects really hurt me, though. It was about two days after taking the medication that I suffered a 24-hour migraine along with flu-like symptoms, high fever, rashes, dizziness, confusion, racing heart, chills, anxiety, nausea, dry mouth, sleep problems, loss of appetite, and ringing in my ears. It has been the worst two days of my life thanks to this medication."

2 / 10
Was this helpful?YesNo
37 Report
  • Hap...
  • Taken for less than 1 month
  • May 25, 2019

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Allegra D is like a magic pill! This April-May, I’ve been suffering horribly from severe allergies and also caught a bad viral cold twice!! Also, I'm terribly allergic to dogs, and during that time, my husband also decided to adopt a dog from the SPCA. I was literally in bed those two months, taking daily cold and allergy meds (switching between regular Allegra/Claritin/Zyrtec), but still have constant sneezing, itchy eyes, post-nasal drip, coughing, and congestion, with not even a minute of relief. I decided to take Allegra D for the first time, and it’s given me my life back. I’ve been so incredibly grateful for this because it’s worked so beautifully for me. I have zero symptoms of allergies (especially to dogs!) and zero symptoms of the medicine's side effects. I’ve been taking it daily for 2 weeks. Allegra D doesn’t work for everyone, but give it a try because it’s saved me, and I’m just so grateful to be able to function normally now (and saved my rescue dog from being returned!)"

10 / 10
Was this helpful?YesNo
18 Report
  • C a...
  • October 13, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I have chronic rhinitis. I was very ill last year, and my immune system hasn't been the same since. My immune system now reacts to everything around me, i.e., I'm allergic to all of my surroundings: dust, pollen, etc. Instead of the typical runny nose and sneezing, the inner membrane of my nose would swell almost completely shut. I was miserable. Accompanied by a nasal spray, Allegra-D was the best thing that's ever been prescribed to me! Although at first, I suffered severe insomnia, the side effects became milder with time."

10 / 10
Was this helpful?YesNo
28 Report
  • Anonymous
  • Taken for less than 1 month
  • September 15, 2013

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I've tried other allergy medications, but Allegra-D is the only one that works. I used to get constant post-nasal drip and have to clear my throat all the time. On this medication, I feel amazing. It does, however, cause insomnia and bad dry mouth. It also makes it so I don't get a full erection. So do I feel better and not have sex, or what?"

9 / 10
Was this helpful?YesNo
27 Report
  • arn...
  • January 20, 2020

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I only needed to take one of these pills to cure my clogged nose. Within hours, I could breathe again, and I haven’t had a stuffy nose since. Usually, I have clogged noses for a week when I catch a cold. I’m so happy I found this."

10 / 10
Was this helpful?YesNo
11 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Myr...
  • May 26, 2017

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I was suffering from a severe sinus infection for over a week, and I was taking Sudafed to help with the pain and pressure, but of course, that did not work for a sinus infection. I started taking the 24-hour Allegra-D for my congestion and inflamed sinuses along with antibiotics, and it helped almost immediately. Every day. I only took it until my infection went away, not continuously. The only side effects were really bad dry mouth constantly and bad drainage of mucus, so I constantly had to clear my throat, which caused my throat to be sore."

9 / 10
Was this helpful?YesNo
14 Report
  • Pab...
  • Taken for 5 to 10 years
  • March 1, 2020

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This medication, Allegra-D 12 hr, has been for me as close to a lifesaver as it can be. No other medication works for me, without an Rx, of course. I take it once every other day, and my nose and sinus remain quiet. I do appreciate Allegra-D 12 hour caller❤."

9 / 10
Was this helpful?YesNo
9 Report
  • Che...
  • Taken for less than 1 month
  • March 7, 2018

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This medicine works great for allergies. However, day five into taking it, I’m experiencing major depression/personality changes. I don’t feel like myself at all, and there’s nothing else in my life that would contribute to this. My personality feels extremely subdued, I’m withdrawn, don’t care about anything or anyone, and negative self-talk has significantly increased... this is not who I am! I’ll be stopping this medication tomorrow."

2 / 10
Was this helpful?YesNo
12 Report
  • Ano...
  • May 26, 2015

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I was prescribed this medication several years ago for allergies. I was told to take it twice a day. It was effective; however, it did cause insomnia to the point the doctor instructed me to take it once a day. It also gave me headaches the first few days taking it. Other than that, it was highly effective."

7 / 10
Was this helpful?YesNo
13 Report
  • gan...
  • April 5, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I have severe pollen allergies, and Allegra-D was the best medicine I ever took, until I could not sleep. It causes insomnia in me, so the trade-off is insomnia versus feeling miserable 24/7. It took 2-3 days before I first received relief. Then there was a huge difference."

9 / 10
Was this helpful?YesNo
16 Report
  • rai...
  • August 18, 2016

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Yes, this medication works to eliminate symptoms of allergies; however, I had a big issue with - what I'm assuming is - a side effect of the medication. When I took the medication, my personality immediately changed; I actually became less talkative and happy, and it severely affected my life to the point where I randomly started crying during school. I'm assuming that the medication put me in a depression-esque state (I've never had depression before, so I can't say for sure), but it altered my personality in ways my personality has never changed for the three days I took it, and people noticed. It was honestly terrifying. Be wary of the side effects when taking this medication."

2 / 10
Was this helpful?YesNo
17 Report
  • Anonymous
  • October 5, 2011

Fexofenadine / pseudoephedrine "This medicine is like magic. I had constant post-nasal drip and congestion before I took this medicine. It was so bad I had trouble sleeping because I couldn't breathe through my nose. I also used to get sore throats frequently due to the post-nasal drip. On Allegra, those symptoms are gone. I can actually breathe like a human and sleep better. The only side effect is dry mouth, but that just makes me drink more water, which is a good thing. I am glad this is available over the counter now, but I hate how you only get 10 at a time."

9 / 10
Was this helpful?YesNo
14 Report
  • sle...
  • Taken for less than 1 month
  • August 29, 2014

For Allergic Rhinitis "Took it around 6:30 am before leaving for work. Experienced terrible insomnia even though I took it early in the morning. Couldn't stay asleep more than three or four hours. Awful stomach pain and loss of appetite. Some itching. Weakness and dizziness when standing too quickly. Dry mouth, so I'm constantly drinking water. Unfortunately, the other OTC medicines didn't work as well as this product. I'm in a lose-lose situation."

9 / 10
Was this helpful?YesNo
11 Report
  • KK5...
  • Taken for 10 years or more
  • December 21, 2012

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I love this. If I don't take it, I ALWAYS end up with a sinus infection and a trip to the Dr. When I do take it, I don't sleep as well, but I'm not tired in between. My major issue is that I am always constipated when I take Allegra-D, and my periods are excruciatingly painful."

9 / 10
Was this helpful?YesNo
14 Report
  • Anonymous
  • October 1, 2008

Fexofenadine / pseudoephedrine for Allergic Rhinitis "When fall sets in, so do allergies where I live. After a trip to the doctor, I was prescribed Allegra D-12 Hour and found that I had the sinus pressure relieved within 2 1/2 - 3 hours. However, when drugs.com lists 'dizziness' as a side effect, they're not kidding. I had to get someone to take me home because I (personally) was too dizzy to even walk straight. So if this is prescribed to you, I would suggest taking it on a day 'off,' such as a weekend, or at night to discover how it affects you personally before you take it on a work day and find out the bad way."

9 / 10
Was this helpful?YesNo
15 Report
  • SGa...
  • February 8, 2021

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I started taking Allegra D when I moved to North Carolina, where pollen is abundant. I began getting headaches that felt like migraines. I went to several sinus and allergy experts, even a neurologist. I had several C-scans and X-rays, but no doctor could find the problem. Recently, one sinus doctor did. It was an inflammation of the tissue lining in the sinuses. She told me to stop using Allegra D and gave me a prescription for a liquid steroid to mix with saline solution twice a day in a special plastic squeeze bottle with a curved nozzle. It has been a lifesaver. I will never take Allegra D again! Inflammation of the sinus tissue is mentioned as a rare side effect for Allegra D, but it should be stressed more."

1 / 10
Was this helpful?YesNo
6 Report
  • She...
  • July 10, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Allegra D is the best medicine for my allergies, and I've taken just about every over-the-counter medicine. I have terrible hay fever, and I'm allergic to almost all grasses, trees, and pollen in my region (Midwest - Illinois). My allergist suggested that I move to Arizona. Unlike Allegra D 12-hour, I'm having trouble with side effects: insomnia, nausea, heartburn, cramping. The stomach-related effects are beginning to taper off, but the insomnia isn't."

9 / 10
Was this helpful?YesNo
17 Report
  • Anonymous
  • Taken for less than 1 month
  • May 12, 2019

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I tried Allegra D 24 as my pharmacy was out of Claritin D. The 1st few days this really didn't do anything for my sinuses, by day 7, I was suffering from such intense side effects that I could not work and wound up with an emergency appointment with any doctor that would see me at my doctor's office. My side effects from Allegra D were anxiety to the 10th power (never had anxiety before), chest tightness, felt like my throat was closing, could not breathe, terrible cough, dry mouth. It has been a horrible few days while waiting for this medication to leave my system. I was even given Xanax to help relieve my anxiety, which, if you have taken it, is no picnic either. I have been taking Claritin D for years and never experienced anything like this."

1 / 10
Was this helpful?YesNo
9 Report
  • syn...
  • Taken for less than 1 month
  • September 25, 2013

Fexofenadine / pseudoephedrine for Allergic Rhinitis "It works pretty well. My only two negatives are that the nasal decongestant in this doesn't work as well. I have to supplement occasionally with Afrin nose spray. I would be incredibly miserable without Allegra."

7 / 10
Was this helpful?YesNo
9 Report
  • Emc...
  • Taken for 5 to 10 years
  • March 10, 2021

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I do not have allergies all year, but just seasonal allergies. When I have flare-ups, I have tried everything from Zyrtec, Claritin, Sudafed, Flonase, Benadryl, and the only thing that has given me instant relief without knocking me completely out has been Allegra-D. It covers my allergies and sinus drainage all at once, and I love that it is just a once-a-day pill. Worth the money by far."

10 / 10
Was this helpful?YesNo
4 Report
  • Ano...
  • Taken for less than 1 month
  • November 7, 2019

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Do NOT take this medicine. It should be illegal. I took it for 3 days, and all 3 days I felt nauseous, dizzy, unmotivated, and depressed. The worst part is I haven’t slept more than 2-3 hours a night. This medication will disrupt your life. I usually take Zyrtec D but decided to try Allegra out - my allergies have gotten exponentially worse on it. I have had severe sinus pressure, a cough, and headaches in addition to all the other symptoms."

1 / 10
Was this helpful?YesNo
10 Report
  • Anonymous
  • November 16, 2017

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This is the only thing that helps me with my allergies. I get symptoms every year in November. It helps with the nasal dripping and opens up my sinuses. The only bad thing is my mouth stays dry all the time. I recommend this to anyone."

9 / 10
Was this helpful?YesNo
6 Report
  • Pit...
  • Taken for less than 1 month
  • February 4, 2019

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This medication works great for allergies. My mom takes it, and she loves it. However, as soon as I take it, I start feeling all those crazy side effects: dizziness, nausea, pain everywhere, headaches, crying spells, etc. I personally won’t ever take it again because it is definitely NOT for me, but it is for people like my mom. So I don’t know. Maybe it just depends on your body because everyone is different."

5 / 10
Was this helpful?YesNo
5 Report
  • Joh...
  • Taken for 5 to 10 years
  • June 29, 2024

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I was prescribed Allegra-D 12 Hour tablets years ago to help with my chronic rhinitis. It helped to keep my nasal passages clear and also resolved a persistent post-nasal drip issue as a result of allergies. I prefer taking the 12-hour tablet versus the 24-hour version since I only need it as necessary. Now that Allegra and Allegra-D are both available without a prescription, I keep both readily available and take it as necessary since I’ve had no side effects."

10 / 10
Was this helpful?YesNo
1 Report
  • Anonymous
  • May 11, 2011

"I am allergic to mold and mildew, short of moving to AZ, I have allergies 24/7, 365 days. I have been on Allegra D for better than 8 years. I have no side effects, and without it, I would not be breathing. I also use a nasal spray when the pills can't keep the nasal passages clear enough for me to breathe (mostly spring and fall). Prescription plans stopped covering it over two years ago, so OTC has cut my costs, but a pain to have to buy every 10 days."

10 / 10
Was this helpful?YesNo
7 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.