Skip to main content

Exenatide User Reviews & Ratings (Page 5)

Brand names: Bydureon, Byetta, Bydureon BCise

Exenatide has an average rating of 6.4 out of 10 from a total of 410 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Exenatide

  • Anonymous
  • April 21, 2012

Byetta (exenatide) for Diabetes, Type 2 "The first week of Byetta 5mcg dose, no side effects, 6 pound weight loss but high blood glucose numbers. My Endocrinologist suggested I try going up to the 10mcg dose. nausea, gas, stomach upset and constipation. I ended up in bed most afternoons. Numbers are now good and I've lost another 4 pounds. Too much lifestyle impairment due to side effects so I went back to the lower dose, still having stomach aches and constipation. I'm giving it time, but so far this has been an uncomfortable experience."

6 / 10
Was this helpful?YesNo
35 Report
  • Amand...
  • Taken for 1 to 6 months
  • May 18, 2015

Bydureon (exenatide) for Diabetes, Type 2 "I started 10 weeks ago and saw an immediate drop in my home testing glucose levels, from double figure mmol readings to 4/7mmol after fasting. I had no side effects at all for the first four weeks but subsequently suffered terrible nausea, overnight hypos, skin rash and the most revolting sulphur/egg-smelling burps (cured immediately by Alka Seltzer if anyone else has the same problem!) I've noticed no reduction in appetite (except when nausea has prevented me from eating at all) but had already reduced my intake to 1200 calories a day in an effort to lose weight. If anything, Bydureon is hindering my weight loss. I often see no loss after a week of eating like Snow White, which is disappointing. Overall delighted though."

9 / 10
Was this helpful?YesNo
28 Report
  • pea
  • January 12, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon for almost 6 months. I also take daily Lantus injections. I maybe have lost an inch or two but no significant weight loss. Reading how it helps so many people is great! My A1c stayed about the same..a little over 8. Guess I need to try something else!"

Was this helpful?YesNo
33 Report

Frequently asked questions

  • MiMiTX
  • April 10, 2015

Bydureon (exenatide) for Diabetes, Type 2 "Started taking Bydureon 6 weeks ago. The first 4 weeks, blood sugars were lower by 15-25 points, no weight loss but happy with BS results. Week 5, began to be very nauseous on and off, being around food or cooking for family difficult. Could only eat bland, room temp/cold foods like half a bagel, granola bar, cereal, bananas. Everything else made me sick. Week 6, nausea much worse without stopping, could not tolerate smell/sight of food, especially meat. Weekend trip with family was ruined because I could not be in any restaurants. Vomited several times. Finally called my doctor and he took me off of it. Waiting to get it all out of my system. Will look for alternative drug."

5 / 10
Was this helpful?YesNo
28 Report
  • Hobie
  • Taken for 1 to 6 months
  • July 11, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I have taken 7 shots of Bydeueron and my numbers have decreased dramatically and I have lost 21lbs. I changed my diet completely, so that helped with the weight loss, but the medicine helps curb my appetite also. The medicine hurts pretty bad going in. The needle size doesn't bother me as much as the pain from the thick medicine. Lumps at each injection site also. Have had more lows since starting the injections. I take 2000 mgs of Metformin and 4mg of Glimeperide daily, so I'm going to talk to my doctor about cutting back on something. "

9 / 10
Was this helpful?YesNo
32 Report

Are you taking this medicine?

  • fabala
  • April 4, 2012

Bydureon (exenatide) for Diabetes, Type 2 "I tried Bydureon for the first time last night. The instructions are complicated, but since this is not a first-line diabetes medication, users should be somewhat familiar with the drill. You have to mix the medication first - you definitely have to follow the instructions. But the manufacturer actually has a toll-free line to walk you through an injection if you're not sure about it. I didn't use the number, I just followed the directions. The needle is huge in comparison to what I've been using with Byetta and Victoza. I have about a quarter-size lump at the injection site today but it doesn't hurt. So far, no side effects...but it's only been 12 hours! "

Was this helpful?YesNo
34 Report
  • belugah
  • Taken for 1 to 6 months
  • September 27, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I am on my 4th month on Bydureon. So far I don't see any weight loss but instead I gained a little. It doesn't suppress my appetite yet in fact on my first 3 months, I noticed that I ate more and always hungry. I lost 25 lbs on Victoza but after a year of using it my weight didn't move down anymore. My Dr. changed it to Bydureon, he wants me to bring down my weight. I have to see him if my numbers are better on this one. Needles are thick but I can handle it. I know the technique now and no bumps at all and pulling the needle is bloodless now. Doing this once a week is very convenient. Just a little worried because of my hypothyroidism, hope it won't create another problem...lets wait a little bit more and see. "

7 / 10
Was this helpful?YesNo
31 Report

More FAQ

  • noraf
  • Taken for 1 to 6 months
  • June 21, 2013

Bydureon (exenatide) for Diabetes, Type 2 "Update: Took 1st shot 2/8/13. Have little nausea but raised bump for every injection and intermittent, intense itching. Numbers seem good but I have changed up diet to Paleo plan. I think that has more to do with good numbers as when I do have the occasional piece of bread or potato, blood sugar shoots up way over 200 and can take many hours to normalize. I've lost 20 lbs since diet change. I am very concerned because so much of my hair is falling out since I started Bydureon. I find Drs. don't like to address anything that the manufacturer does not have on their list of side effects. "

7 / 10
Was this helpful?YesNo
31 Report
  • Ms Di...
  • Taken for 1 to 6 months
  • May 23, 2018

Bydureon (exenatide) for Diabetes, Type 2 "I’ve been on bydureon since January 2018, I’ve lost 35 pounds in 4 months! I’m happy this medication has lowered my A1c from 13.6 To 6. I don’t like needles, but to get me health under control I’m with this medication for the long all. So far doing good!"

10 / 10
Was this helpful?YesNo
20 Report
  • Anonymous
  • April 5, 2010

Byetta (exenatide) for Diabetes, Type 2 "I've been on Byetta 10 mg for almost 1 month. I have lost 16 pounds already without really trying. The worst thing is the feeling sick after you eat (I feel the worse about 1 1/2 hours after taking the shot). Some days are better. No constipation like some people reported, more loose stools than anything. I plan to stay on this medicine for a long time!"

8 / 10
Was this helpful?YesNo
37 Report
  • Dilly...
  • May 23, 2016

Bydureon (exenatide) for Diabetes, Type 2 "4 injections so far and experienced the nausea which initially lasted three days and slowly is backing down. I have no problem with the injection. I don't know if this will help others who develop a lump after their injection but I immediately massage the area on my belly then use ice for about 10 minutes. No rash no pain no lump. I don't know if this is the answer to the lumps or I'm one of the lucky ones but it might be worth a try. My appetite is practically nonexistent. I am experiencing the bloat. I seem to be able to not eat more than seven or eight bites of food without bringing it back up. I also have the most embarrassing huge burps you have ever heard. Also take 2000 mg "Metfartin""

8 / 10
Was this helpful?YesNo
24 Report
  • adria...
  • Taken for 2 to 5 years
  • December 8, 2018

Bydureon (exenatide) for Diabetes, Type 2 "Hello everyone, I'm from the U.K. I have been taking Bydureon for about 30 months alongside Metformin and Jardiance. I have lost weight and I'm now down to 92kg (202 lbs for those in the USA), that's about 10kg since I started taking weekly Bydureon. I find it makes me feel full most of the time and I sometimes get constipation but my results are quite good. My HbA1c has dropped and I've managed to keep off insulin for now. I wonder if one of the main ways of how it works is that the weight loss can restore my own insulin production rather than the drug itself. All medication for Diabetics is free here so I'm unaware how much it costs and we are treated with the medication that most suited to us - irrelevant of the price. The doctors have been very good at supporting me over the last 10 years of my Diabetic journey. I've never really thought about the costs. Best wishes to everyone. Adrian."

8 / 10
Was this helpful?YesNo
18 Report
  • Carol...
  • Taken for less than 1 month
  • May 3, 2012

Bydureon (exenatide) for Diabetes, Type 2 "Expect high numbers for awhile, as I understand the medicine usually takes two to six weeks to fully become active in your body. I have been on it under a week and can see my numbers slowly dropping again I am nearing 200 and usually run 120-165. Did see some high 200's but this may be normal I was told. Just check with your doctor if you are concerned. Once I get used to the weekly injections, and after leveling out I am sure I will like this over daily injections."

5 / 10
Was this helpful?YesNo
32 Report
  • DB ADEL
  • March 4, 2017

Bydureon (exenatide) for Diabetes, Type 2 "I was diagnosed with type 2 Diabetes 4 years ago, and had several different brands of tablet medication but had side effects in one form or another. Nothing seemed to control my sugar levels. The last 2 years I had been on metformin 500mg tablets morning and night, with 30 mg of diamicron. My sugar spiralled up to between 13 & 21 and a burning when urinating. Saw my GP and was given treatment for infection but was to no avail. Doctor saw my various tablet combinations I have had over the years, and recommended me trying Bydureon 2mg weekly injection and it has absolutely changed my life. Been taking for 4 months now, no burning urinating, my sugar now stable, 5.2 & 7.1, lost 20kg, more energy, no side affects at all. To me it's a WONDER drug"

10 / 10
Was this helpful?YesNo
22 Report
  • mulee...
  • Taken for 5 to 10 years
  • August 25, 2014

Byetta (exenatide) for Diabetes, Type 2 "Was on the 5mcg and increased to 10. Had the usual nausea and lost about ten pounds. A1c leveled out in the high 6's to low 7's. Got ugly last fall/winter and dropped another 35 lbs. BMI is now normal with 65 lbs lost from an initial 235lb start. Have been having a problem with low (50'5 and 60's) sugars within 2 hrs of injection/eating. This started 3 months after the latest weight loss. I was forced to sugar load with glucose and fruits to counteract the Byetta and stopped it last week (just too dangerous. I am going to ask to be put on the time release and then adjust the Glucophage to try to get a stable dial in. Testing like a mad dog my fingers are a mess. If the time release doesn't cut it I will try going back to 5mcg."

10 / 10
Was this helpful?YesNo
27 Report
  • Trade...
  • Taken for less than 1 month
  • February 9, 2020

Bydureon BCise (exenatide) for Diabetes, Type 2 "On my fourth week of Bydureon BCise, no side effects that I have noticed other than the injection site. All four sites have a hard lump under the skin, and burn and itch (mild irritation, I would say 3 on a scale of 1-10)."

4 / 10
Was this helpful?YesNo
15 Report
  • Ellen...
  • December 4, 2014

Bydureon (exenatide) for Diabetes, Type 2 "Just had my second injection of Bydureon. First one went fine-just little bits of nausea. The second one was two days ago. Last night I woke up sick as a dog with horrible vomiting and diarrhea. I've been ill for hours and am now missing work. That makes me unhappy. Guessing it's the Bydureon but maybe stomach virus. Will check in with my dr today. Byetta I could not tolerate at all. I'm wondering if this one is the same."

6 / 10
Was this helpful?YesNo
26 Report
  • jbran
  • October 11, 2012

Byetta (exenatide) for Diabetes, Type 2 "I was on Byetta from April 2010 until Aug 2012. My sugars were great, I lost weight, but my nails became thin and weak, my hair became brittle and balding. I am now 57. My doctor ran test, my thyroid is find. My skin is EXTREMELY dry. I read that there were complaints of hair loss - so I quit taking it (my Dr's. suggestion). I only hope my hair will get healthier and COME BACK!"

8 / 10
Was this helpful?YesNo
30 Report
  • evelyn
  • Taken for 1 to 6 months
  • September 7, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon for 3 months now and have found it to be effective at lower my blood sugar and decreasing my appetite. The side effects, however, have caused me to discontinue using it per my doctor's instructions. I have been experiencing systems likened to having a stomach virus, bloated stomach, nausea and diarrhea, about every third to fourth week of the month. The effects are bad enough that I have had to miss work. I haven't experienced any knots at the injection site, but my goodness that's a large needle that has to be used!"

10 / 10
Was this helpful?YesNo
28 Report
  • Johng...
  • March 1, 2017

Bydureon (exenatide) for Diabetes, Type 2 "Within 2 weeks saw blood glucose more than half to good levels I've not seen for years (literally) no major side effects - felt sick twice within a day or two of first dose but apart from that all ok. Injecting in fatty tissue of stomach hardly any pain. Very well designed device and needle almost painless. I would recommend this for T2s who have gone to max on oral meds and need that extra help, this really is the magic bullet for me. I can handle weekly injections but not daily that's too much imho."

10 / 10
Was this helpful?YesNo
21 Report
  • patso...
  • June 16, 2008

Byetta (exenatide) for Diabetes, Type 2 "I started on Byetta about 4 months ago. I have lost 45 lbs and have never felt better. My blood sugar readins have gone from 275 to 135 2 hours after a meal. I take the 5, doctor tried to put me on 10 but was vomiting after meals and had to go back to five. This drug has been a God send for me."

10 / 10
Was this helpful?YesNo
37 Report
  • diabe...
  • March 11, 2008

Byetta (exenatide) for Diabetes, Type 2 "i was on byetta from for 6 mths it was good to control the sugar levels but i did not find any other benefit as to what the drug claim about losing weight....i thought the expense was to much for the not so stellar results....."

4 / 10
Was this helpful?YesNo
37 Report
  • Lauri...
  • June 20, 2008

Byetta (exenatide) for Diabetes, Type 2 "I just started Byetta 4 days ago on 5mg and will increase to 10mg in a month. I have been taking 45mg of Actos before starting Byetta. Actos did bring my glucose into the mid to low 100's just as Byetta does, but I have loads more energy on Byetta. I didn't realize that I was dragging because I lost my energy slowly over the years. After 2 days on Byetta I appreciate feeling just normal again. I love Byetta."

10 / 10
Was this helpful?YesNo
37 Report
  • Deene...
  • December 13, 2017

Bydureon (exenatide) for Diabetes, Type 2 "I started using Bydureon 5 weeks ago. I have not had any problems using this med. I was very afraid of trying it from some of the comments I read. I take it out of refrigerator 15 minutes before hand and follow the instructions to a tea. I have had one time I bruised but nothing bad. I also had a lump one time but it did not hurt at all. I have lost 14 pounds since I started the medication. I have not changed my eating habits. I find I feel better in the mornings since using Bydureon. I will be going in this week to have my A1C tested. Then I will know more. Hope it continues to work for me."

Was this helpful?YesNo
19 Report
  • Doug
  • November 22, 2016

Bydureon (exenatide) for Diabetes, Type 2 "I have used this Pen 5 months and so far I have more energy, sugars lower. Feel better overall. A little bleeding from injection, but I can live with that. AIC pending but I know it will be much better. Definitely worth a try."

9 / 10
Was this helpful?YesNo
21 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.