VyLibra and Depression: What Users Say

• Ano...
• November 7, 2020

For Birth Control "Before I started taking Tri-Vylibra, I was on the mini-pill, which made me super depressed and gave me bad anxiety. It also broke me out and gave me my period twice a month. I switched to Tri-Vylibra a little over a month ago. So far, I have had absolutely no weight gain, my skin is starting to clear up, and I am back to being happy. Also, I got my period two days after I started the reminder pills, and it was very light. I usually have bad cramps, and this time I only had cramps on the first day of my period, but they were very minimal. I highly recommend this birth control."

• Liz...
• Taken for 1 to 6 months
• April 22, 2020

For Birth Control "I took Ortho Tri-Cyclen for years and loved it... until it stopped working. From then on, I have jumped from birth control to birth control trying to find one that actually works for me. I have too much estrogen and struggle with acne, unnecessary moodiness, and depression. Tri-VyLibra seemed to be working just fine until I started having terrible chest pain. I have never had chest pain in my life until I took this birth control. I would not recommend taking it!"

• Jay...
• Taken for 1 to 6 months
• March 15, 2021

For Birth Control "I do not recommend. This has made me extremely nauseous. I take this pill at night and it’s so hard sleeping because my tummy is constantly hurting. It makes me not want to eat because I’m so scared of throwing up. I’ve lost so much weight on this pill. It also hasn’t been doing a good job of clearing my acne. I’ve been on this pill for 3 months. It’s also made me very depressed."

• Ang...
• Taken for 2 to 5 years
• October 21, 2021

For Birth Control "I’ve been on this birth control for 3+ years. In that time, I’ve gained 30 lbs, had the worst panic attacks and depression. After being on this pill long-term, I am going back to Loestrin. The past two cycles, about a week AFTER my period, I became horribly ill. Extreme nausea, vomiting, lightheadedness, lasting about 1-2 weeks on and off. I have been too sick to work and have missed weeks of work combined just in these past two menstrual cycles. I have been to the ER twice, urgent care, GI, primary care, and OBGYN. I truly didn’t think birth control could cause these symptoms just now after I’ve been on it for years. My OBGYN (and GI to be honest) said the only thing that could be causing these regimented bouts of illness could be my hormonal birth control and that it is, in fact, possible for the body to just change. I’m so excited to stop this birth control. One star because I never got pregnant on it."

• BBa...
• Taken for 6 months to 1 year
• March 10, 2021

For Birth Control "I wish I would’ve read reviews before taking this. I never had any issues with depression before, I woke up sad every day. I felt so anxious and paranoid. I’ve lost at least 20 pounds because of the depression. I’ll probably never use birth control again. I’ve been off of it for about three weeks now, and I finally feel back to normal."

• Anonymous
• February 28, 2022

For Birth Control "I initially got on this birth control for my acne, but it didn't seem to help, and it just made my acne worse. My boyfriend and I were a very active couple, very intimate, and after being on VyLibra for a month, I noticed I had no interest in my partner whatsoever, to the point I would even back away from a simple kiss. After being on it for 3 months, things just got worse and worse until I stopped taking it, and after a month of not taking it, I was 'back to normal.'"

• Car...
• Taken for 1 to 6 months
• February 16, 2021

For Birth Control "Worst switch-over ever. Pharmacist gave this to me instead of Sprintec (previously on a different BC, I changed to another brand and had zero problems), but this was the WORST. I have PMS, but this made every day of the month worse. I was super flustered, couldn’t focus/remember what task I was doing, increased anxiety, and felt depressed. Had breakthrough bleeding and severe cramping. I had zero motivation and could sense a weird type of depression that I’ve never experienced hit me right after starting the pill. I’m a newlywed with a good job - this is absolutely NOT my norm. I requested to switch back ASAP, and my doctor told me to finish the pack. I am back on my other brand and feel an immediate difference in every way."

• Car...
• Taken for 1 to 6 months
• February 16, 2021

For Birth Control "Worst switch-over ever. Pharmacist gave this to me instead of Sprintec (previously on a different BC, I changed to another brand and had zero problems), but this was the WORST. I have PMS, but this made every day of the month worse. I was super flustered, couldn’t focus/remember what task I was doing, increased anxiety, and felt depressed. Had breakthrough bleeding and severe cramping. I had zero motivation and could sense a weird type of depression that I’ve never experienced hit me right after starting the pill. I’m a newlywed with a good job - this is absolutely NOT my norm. I requested to switch back ASAP, and my doctor told me to finish the pack. I am back on my other brand and feel an immediate difference in every way."

• Lio...
• Taken for less than 1 month
• May 31, 2021

For Birth Control "The local women's health clinic prescribed VyLibra because I was going on vacation to see my boyfriend, and I wanted to skip my periods. After a few days, I started feeling awful anxiety and completely lost interest in any kind of intimacy, and always being tired. A couple of days after, I started getting the mood swings, crying at the drop of a hat, and depression. I even became paranoid and canceled my trip, which I immediately regretted. The vaginal dryness is annoying, and I even lost interest in my artwork (I'm an artist, and this is the worst thing ever!). I've been on the pill before (Sprintec) and never had these problems before. I wish I'd known about these side effects before I started. Another weird one is I can normally remember my dreams, but now it's like I'm not dreaming at all. I'm not even a whole month on these things, and I want to quit. Definitely do not recommend."