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Dotti and Depression: What Users Say

Depression: mentioned by 4 users (9.1%)

Based on user experiences from 44 Dotti reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 29.5%
mood swings 18.2%
insomnia 15.9%
irritability 13.6%
night sweats 11.4%
depression 9.1%
fatigue 9.1%
headaches 6.8%
nausea 6.8%

Reviews for Dotti

  • Not...
  • Taken for less than 1 month
  • February 8, 2023

For Postmenopausal Symptoms "I was given Dotti as I could not get my usual medication. Within a week, I was feeling depressed, was feeling hot all the time, and only getting 4 hours of sleep, and I have had issues with rage and have been isolating myself. This drug is horrible. Thank you, everyone, for having left reviews."

1 / 10
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46 Report
  • fru...
  • Taken for 6 months to 1 year
  • February 20, 2021

For Postmenopausal Symptoms "I moved, which required changing pharmacies. I was on a different patch in my other state, and my new pharmacy offered Dotti. I had no idea why my hormone levels were dropping, why my moods went from happy and energetic to exhausted and depressed, with bouts of anger. I would not recommend this manufacturer. It started off okay, but I was still cycling through my old patches. A couple of weeks later, I lost all interest in anything and even had to make an appointment to see someone for major depression (never felt that before). Please beware. I have been using Dotti for 3 months and had to request pills on top of it to compensate for the drop in my levels."

1 / 10
Was this helpful?YesNo
22 Report
  • fru...
  • Taken for 6 months to 1 year
  • February 20, 2021

For Postmenopausal Symptoms "I moved, which required changing pharmacies. I was on a different patch in my other state, and my new pharmacy offered Dotti. I had no idea why my hormone levels were dropping, why my moods went from happy and energetic to exhausted and depressed, with bouts of anger. I would not recommend this manufacturer. It started off okay, but I was still cycling through my old patches. A couple of weeks later, I lost all interest in anything and even had to make an appointment to see someone for major depression (never felt that before). Please beware. I have been using Dotti for 3 months and had to request pills on top of it to compensate for the drop in my levels."

1 / 10
Was this helpful?YesNo
22 Report
  • LKa...
  • November 12, 2020

"I am taking estradiol for Turner syndrome. The pharmacy OscoDrug switched from Mylan 0.025 generic estradiol patch to Dotti with terrible side effects including local redness and itching, as well as systemic ones: increased migraine frequency, depression, mood swings, fatigue, generalized malaise, and body aches. Mylan had some of these but to a lesser extent. The insurance will not cover Vivelle-Dot brand name, it seems that's the best on the market so far. We'll go through the appeal process. Generally, insurance and the pharmacy both want to push a cheap variation like Dotti. You need to fight for Vivelle-Dot like for everything that's right, don't give up, it's all worth it!"

1 / 10
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22 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.