Skip to main content

Imvexxy User Reviews & Ratings (Page 2)

Imvexxy has an average rating of 5.0 out of 10 from a total of 65 reviews on Drugs.com. 35% of reviewers reported a positive experience, while 44% reported a negative experience.

Reviews for Imvexxy

  • Yamacl
  • May 11, 2020

For Atrophic Vaginitis "I didn't notice much if any improvement after 4 months of 10 mcg twice a week, but I stopped it as I noticed a quarter sized bald spot on the front of my hair that wasn't there before I started taking it. In fact, I have thick hair otherwise, and now there is hair all around this bald spot but it is smooth in the middle with no hair growth! : I don't know if it is from this medication but it seems to coincide with taking it and I don't take any other medications. Now I am concerned I won't get hair to grow back there, or if more bald spots appear. I am 54, and no family history of balding, both my mom and father in their late 70s have a full head of hair with no balding."

2 / 10
Was this helpful?YesNo
27 Report
  • DKano
  • Taken for 6 months to 1 year
  • February 5, 2020

For Atrophic Vaginitis "I’ve used imvexxy for about a year with no problems. It does work for me although it’s a nuisance having to remember to insert — which I do at night. My biggest complaint is they specify keeping it within a very narrow temperature range. Fridge would be too cold but when we have a hot spell in summer I have to keep the capsules in the basement"

8 / 10
Was this helpful?YesNo
24 Report
  • Kat
  • Taken for 1 to 6 months
  • August 21, 2020

For Atrophic Vaginitis "I tried Imvexxy for 4 weeks and then tried Intrarosa for 4 weeks and decided on Imvexxy. I have been on it for 2 months now and am very pleased. The first 2 weeks, I had a mild headache pretty immediately after using the drug, but thankfully I no longer have this side effect. A big bonus has been much better sleep since taking Imvexxy. The Intrarosa also worked for the Vaginal Dryness, but also was more cumbersome with daily usage requirement, and also made it hard to fall asleep at night."

8 / 10
Was this helpful?YesNo
21 Report

Frequently asked questions

  • Karen...
  • Taken for 1 to 6 months
  • April 23, 2020

For Dyspareunia "Three months on imvexxy now. No issues at all other than a minor itch I had the first month I was on it but the minor issue went away after month two. Now on my third month going into my fourth month and things have been very positive."

10 / 10
Was this helpful?YesNo
21 Report
  • This...
  • October 10, 2021

For Atrophic Vaginitis "I had tried so many things to deal with vaginal atrophy. Intercourse was extremely painful and I thought my sex life was over. Then my nurse-midwife suggested Imvexxy. Game changer. After a week, the results were incredible. Some reviewers talk about the discharge, but I found if you insert it a little higher and at night (wear underwear), there's far less. I haven't noticed any of the side effects some folks have. I take 10 mcg 2x per week. I also wish, though, that there were no dyes in this product. AND they did hike the price! Hopefully, I can get this resolved."

10 / 10
Was this helpful?YesNo
15 Report

Are you taking this medicine?

  • 3vs
  • Taken for 6 months to 1 year
  • November 12, 2020

For Atrophic Vaginitis "Started with Imvexxy 10mcg and severe migraines coming back (also noticed out of nowhere, developed atrial fibrillation? Sad because the product worked great and nearly immediately for the painful intercourse! Afib stopped and decided to try the lower dose at 4 mcg. Now I have severe pressure in the pelvic area. Feels awful. First I thought it was due to increase physical activity but now I think it is the product because it immediately feels worse again after inserting and lying down. Have constant feeling of urgency. Worried about prolapse but went to OB/gym and she said that was fine. I am sad but think I will have to stop as the misery of constant feeling pressure (like a UTI or a pressure like wanting to give birth) is awful!"

5 / 10
Was this helpful?YesNo
18 Report
  • Lenny
  • Taken for less than 1 month
  • March 24, 2020

For Atrophic Vaginitis "I have tried Imvexxy twice the first time with the lower dosage and I felt improvement with no side effects and then after the first two weeks I developed a very bad yeast infection. When I went to the doctor she thought this might be a coincidence and she put me on the higher dosage. I felt breast tenderness and insomnia . And again after two weeks once a day the yeast infection is starting up. Need to call the doctor in the middle of the COVID-19 self isolation! Worried."

3 / 10
Was this helpful?YesNo
20 Report
  • XENA
  • Taken for less than 1 month
  • September 11, 2022

For Atrophic Vaginitis "This medication gave me a terrible rash and I broke out in hives after the first use. It was from my hips down and itched terrribly! It has been over a week and the hives/rash are still present. OB prescribed something to help with the itch, but it makes me drowsy. This has been a terrible experience I would not recommend this or wish this on anyone."

1 / 10
Was this helpful?YesNo
10 Report
  • Menop...
  • Taken for 1 to 6 months
  • November 27, 2022

For Atrophic Vaginitis "I started taking 10mcg Imvexxy one month ago. I used it daily for two weeks then went to twice per week. I found it easy to use. All was fine for two weeks except for the bad discharge and then at week four, I started having extreme fatigue, nausea, diarrhea, loss of appetite, chills and hot flashes, and then extremely painful pressure in my pelvic area. Since this is the only change I have made, I am convinced it’s Imvexxy."

1 / 10
Was this helpful?YesNo
9 Report
  • Feli
  • Taken for less than 1 month
  • March 31, 2023

For Atrophic Vaginitis "I just started using Imvexxy and although initially it felt like it was helping, things have taken a turn for the worse. I have mild cramping, itching burning, and increased urination with burning. Got checked for UTI and none present. The only thing that has changed as been the introduction of Imvexxy. I'm also having stomach issues. Imvexxy is not for me. I had high hopes but the side effects are intolerable."

2 / 10
Was this helpful?YesNo
7 Report
  • Vanessa...
  • Taken for less than 1 month
  • September 13, 2023

For Atrophic Vaginitis "My OB/GYN recommended Imvexxy, after another OTC, Revaree, did nothing to help with my vaginal atrophy. I was reluctant to take any HRT, and never would have brought it to my doctor's attention if she did not ask me how my sexual health was. I had been unable to have intercourse for over 4-5 years."

10 / 10
Was this helpful?YesNo
5 Report
  • Unhappy...
  • Taken for 6 months to 1 year
  • July 23, 2021

For Atrophic Vaginitis "IMVEXXY did not work for me. I'm 6 years post menopause. Insurance quit covering Premarin cream (which worked great) and switched me to IMVEXXY. I tried the 4 & 10 mcg strengths. Neither took care of the dryness, irritation or urinary symptoms. It caused a burning irritation that felt like a UTI after each use. I used it at night and it was messy enough to require a panty liner. I also had some hair loss which may or may not be related."

1 / 10
Was this helpful?YesNo
12 Report
  • Rose...
  • Taken for less than 1 month
  • February 10, 2023

For Atrophic Vaginitis "I’m 62, had a hysterectomy at age 40, did not do HRT, and am not sexually active. I needed Estrace 3 times a week on the opening of my vagina for dryness. In 2022, however, I had 6 UTIs and lower back pain. My urologist thinks I have cystitis and vaginal dryness and prescribed 10 mcg of Imvexxy twice a week. I’ve used Imvexxy for three weeks and have been experiencing night sweats and a pink discharge from the medication. I use a leftover applicator to insert the capsule, not my fingers. I insert it more than 2 inches but the discharge still leaks out. The opening of my vagina still feels dry. I’ll have to see if the UTIs go away with continued use."

7 / 10
Was this helpful?YesNo
6 Report
  • Blueyes
  • Taken for 2 to 5 years
  • May 13, 2022

For Atrophic Vaginitis "Started Imvexxy fall of 2019. Seemed to be working fine. Summer of 2021 I started having heavy discharge on all days except the day after nightly dosage. I also started having unusual hip pain and mobility. Experienced migraines as well. Have stopped taking mvexxy spring 2022 and after the 1st week off, hip pain and mobility improving and discharge is much less every day."

4 / 10
Was this helpful?YesNo
7 Report
  • Girly...
  • Taken for 1 to 6 months
  • November 21, 2021

For Atrophic Vaginitis "Pink discharge scared me, should not have a dye, can be confused with blood. Pinkness on a tissue can be a lot of things that are serious, such as pink or light amount of blood on a tissue from bladder cancer. Its very hard to figure out if it is blood, and, where it might have come from if you see a pink color. Also, I wonder how much drug actually slips out when the pink coating dissolves in the discharge. Prescribed by my ob/gyn and urologist for UTI/atrophy/dryness seems to help somewhat. Been using for 6 weeks. Color of it needs to change. Needs an applicator."

8 / 10
Was this helpful?YesNo
8 Report
  • Anonymous
  • Taken for 1 to 6 months
  • December 25, 2022

For Atrophic Vaginitis "I’ve been using Imvexxy for about 1 month. I’ve noticed hot flashes and night sweats have increased. I’m having leg heaviness and tiredness as well as lower back pain. Insomnia has also gotten worse. I get a burning sensation and discharge after usage. I take 10 mcg every two days. I will reduce my usage to once a week and see if the symptoms resolve. I will keep you posted."

3 / 10
Was this helpful?YesNo
4 Report
  • Abbie
  • Taken for 1 to 2 years
  • June 2, 2023

For Atrophic Vaginitis "Just read all these reviews after having used this product for about a year and a half. I was on a strong dose at first and it made me very crampy so my doctor reduced the dose to 10 mg which still seems like a lot compared to the reviews that I’ve been reading. I took it half as often as she suggested. It worked. However, I had the worst smell coming from my armpits and I’ve never been a smelly armpit person, my hair is thinning which I realize is a side effect according to the reviews, and I had weird sensations in my breast. So I will be discontinuing the use of this product. Good luck ladies."

3 / 10
Was this helpful?YesNo
3 Report
  • Regis...
  • Taken for 6 months to 1 year
  • November 7, 2021

For Dyspareunia "My physician prescribed Premarin vaginal cream, with good results. After a year CVS, my prescription provided, notified me they would no longer cover any of the cost of Premarin and recommended the physician order Imvexxy 10mcg twice a week. Even using this medication faithfully, I have had minimal to no improvement in the dyspareunia and the residual headaches are miserable."

1 / 10
Was this helpful?YesNo
5 Report
  • Anonymous
  • Taken for 2 to 5 years
  • January 29, 2022

For Atrophic Vaginitis "Prescribed to me for surgical menopause (hysterectomy in my 30’s). Worked to help prevent UTI and vaginal dryness. Side effects: diarrhea, headaches and body aches. Sucks…. But big pharma keeps you coming back for side effects and other problems. Gotta keep you a customer I guess. 4mcg twice a week."

4 / 10
Was this helpful?YesNo
4 Report
  • So...
  • Taken for less than 1 month
  • October 22, 2022

For Atrophic Vaginitis "Just started using a week ago on lower dose 4mcg. The only side affect has been joint pain: knees, elbows and hips. Cost was $75 for 18. $35 for maintenance pack of 8. Find the prescription card online. I can deal with side effect if sex isn’t painful. I'm 54 and not expecting my sex life to be over yet."

7 / 10
Was this helpful?YesNo
3 Report
  • Utah50-
  • Taken for 6 months to 1 year
  • February 2, 2023

For Atrophic Vaginitis "Imvexxy has been effective in treating Atrophic Vaginitis. However, after having been on it for some time, I have gained nearly 10 pounds, experience hair thinning, 'full' abdomen and thigh cramping as well as my hot flashes have returned. Interestingly the trials that were conducted for this medication only covered women for 12 weeks so could side effects increase with long-term use? My insurance doesn't cover this medication and I will be stopping it once I complete this month."

6 / 10
Was this helpful?YesNo
2 Report
  • Cindi
  • Taken for 1 to 6 months
  • June 7, 2024

"My doctor gave me some samples of Imvexxy, and it worked great. By the time I got the prescription and began using it, the result was not the same. I thought Imvexxy would be my saving grace, but it wasn't. Easy to use except the morning after discharge was stiff on my underwear and irritating, so I changed underwear during the day."

5 / 10
Was this helpful?YesNo
0 Report
  • Wengl...
  • Taken for 10 years or more
  • July 10, 2018

For Atrophic Vaginitis "I have been taking this suppository for the last 15 years in Europe and it prevented dryness and shrinking. I am mid 70 and my moisture has not changed."

10 / 10
Was this helpful?YesNo
61 Report
  • Resa
  • Taken for less than 1 month
  • June 26, 2019

For Atrophic Vaginitis "l used imvexy for four nights and it left me swollen inside and out with a major infection , long story short, l'm allergic to the outer coating ."

Was this helpful?YesNo
36 Report
  • Diner
  • Taken for 1 to 6 months
  • April 17, 2021

For Atrophic Vaginitis "Product worked for vaginal problems. However, had joint pain and swelling, couldn't sleep at night. Anyone else had this problem?"

2 / 10
Was this helpful?YesNo
22 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.