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Estradiol / levonorgestrel and Weight Gain: What Users Say

Brand names: Climara Pro

Weight gain: mentioned by 4 users (8.2%)

Based on user experiences from 49 Estradiol / levonorgestrel reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 14.3%
bleeding 12.2%
mood swings 10.2%
weight gain 8.2%
pain 6.1%

Reviews for Estradiol / levonorgestrel

Commonly mentioned side effects
  • Lad...
  • Taken for less than 1 month
  • April 26, 2022

For Postmenopausal Symptoms "I am 50 years old. I was experiencing all the signs of menopause. I was having trouble sleeping because of hot flashes, migraines due to estrogen fluctuations, mood swings, weight gain, etc. I was starting to feel like I was going crazy. I really researched this patch because I was afraid of side effects and I also pride myself on taking no medications, but I just couldn’t take it anymore, so I decided to give it a try. The first week I had some major mood swings, but they went away by the 2nd week. I am on week 3, and I already feel so much better. I can sleep through the night without hot flashes, which has given me more energy during the day. The patch is easy to put on and stays on. My only complaint is the ugly black text on the patch (why?). I would recommend this patch to a friend."

10 / 10
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18 Report
  • Mar...
  • Taken for 1 to 2 years
  • May 17, 2018

For Postmenopausal Symptoms "I actually like the Climara Pro patch quite a bit. Even with the side effects. Here is my summary: Pros: no more hot flashes. Mine were often and horrible. No more vaginal dryness. No more itchy skin. I feel sexual again. Very few mood swings. I feel good!! Better with it than I did without it!! Cons: I never know when I might bleed! I can go 3 or 4 months with no bleeding, and then all of a sudden, I will bleed for a week or so! I have to have intravaginal ultrasounds 3 times a year to watch the endometrial thickness. If it thins out too much, then I need progesterone. Pain in the butt to monitor this balancing act. I have gained 17 lbs since starting this patch. Worst of all is that the backing on the patch is extremely hard to get off! I now keep these patches in the refrigerator, and the back comes off perfectly. To the people at Bayer: why don't you fix this situation since it obviously is a problem?"

6 / 10
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28 Report
  • Jah...
  • Taken for 1 to 6 months
  • February 23, 2022

For Postmenopausal Symptoms "I’ve experienced extreme night sweats and hot flashes. Got on Climara for two months. I’ve been free of all menopause symptoms. However, I’ve been experiencing joint pain and extreme bloating to the point of being uncomfortable. Oh, and let’s not mention weight gain and uncontrolled appetite."

8 / 10
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5 Report
  • Squ...
  • February 26, 2021

For Postmenopausal Symptoms "At first, I was excited to use this 1x/week easy patch! Had no problems with it sticking. It helped me sleep better too, BUT unfortunately, it wasn’t for me. My breasts were getting sore, painful, sensitive (not good for boudoir), and I was putting on extra weight fast. I stopped taking it. Within a week, I started bleeding. Be wary, ladies. It’s not for everyone, but I really wish it was. Stay well."

7 / 10
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6 Report

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