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Esomeprazole / naproxen and Diarrhea: What Users Say

Brand names: Vimovo

Diarrhea: mentioned by 11 users (18.3%)

Based on user experiences from 60 Esomeprazole / naproxen reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 18.3%
stomach pain 11.7%
upset stomach 11.7%
heartburn 5.0%

Reviews for Esomeprazole / naproxen

Commonly mentioned side effects
  • dns...
  • July 26, 2016

Esomeprazole / naproxen for Osteoarthritis "Horrible experience. Took for 14 days as directed and by day 11, there was blood in my bowel movements. Days 12 and 13 had me doubled over with severe stomach pains and watery diarrhea up to (no exaggeration... 18 times a day). I figured that it was from this new medication and stopped immediately. Stomach pain subsided, but now need a colonoscopy to be sure that I am okay. Also gained 8 pounds in these 2 weeks. Really helped with my hip pain, but no thanks... I'd rather deal with hip pain than this nightmare."

1 / 10
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31 Report
  • Wil...
  • Taken for less than 1 month
  • August 24, 2018

Esomeprazole / naproxen for Osteoarthritis "I have only taken 2 pills! One last night and one this morning. I have had the worst stomach pains and diarrhea ever in life! I would rather have the agony. I was given it from my stand-in nurse/doctor, he told me it was new to the books. Why did I even try to take it? I will not take it again."

1 / 10
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22 Report
  • Bec...
  • Taken for less than 1 month
  • June 19, 2019

Esomeprazole / naproxen for Osteoarthritis "Have been on meloxicam for approx. 2.5 months for hip pain. Ortho doc decided to put me on Vimovo. Took my first dose on a Friday morning. By Sunday morning, wasn't feeling well in my stomach. Decided not to take Sunday night pill. Then the diarrhea started on Monday. OMG! Stomach pain, so far 3 days of watery stools, gas (both ends). Went to gastro doc yesterday, and they have me set up for a slew of tests, but... I'm really wondering if the Vimovo didn't cause all of this. I did have 1 bloody stool on Thursday before I started taking Vimovo, but none since. So it could be something else... but I'm not ever taking Vimovo again. Too much of a coincidence!"

4 / 10
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18 Report
  • Bec...
  • Taken for less than 1 month
  • June 19, 2019

Esomeprazole / naproxen for Osteoarthritis "Have been on meloxicam for approx. 2.5 months for hip pain. Ortho doc decided to put me on Vimovo. Took my first dose on a Friday morning. By Sunday morning, wasn't feeling well in my stomach. Decided not to take Sunday night pill. Then the diarrhea started on Monday. OMG! Stomach pain, so far 3 days of watery stools, gas (both ends). Went to gastro doc yesterday, and they have me set up for a slew of tests, but... I'm really wondering if the Vimovo didn't cause all of this. I did have 1 bloody stool on Thursday before I started taking Vimovo, but none since. So it could be something else... but I'm not ever taking Vimovo again. Too much of a coincidence!"

4 / 10
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18 Report
  • Eca...
  • May 27, 2023

Esomeprazole / naproxen for Osteoarthritis "This medication is awful. After 4 days of taking it, I had diarrhea, stomach cramps, dizziness, and weakness. Why is this medicine on the market? I took this after eating, and I still feel sick. This medicine goes in the bin!"

2 / 10
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3 Report

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  • Din...
  • August 24, 2016

For Osteoarthritis "Great for relief of back pain, but severe side effects. Migraine, vomiting (blood present!!!), diarrhea, and severe stomach cramps (I couldn't stand up with the pain), even for a couple of days after I stopped taking them. Could only manage 6 days of a 14-day prescription. Just not worth it! Would rather deal with the back pain."

3 / 10
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  • con...
  • Taken for 1 to 6 months
  • March 28, 2016

For Osteoarthritis "Medication does help with lower back spasms. I found I was able to sleep once the drug kicked in. Taken only when needed, as prescribed by the doctor. Side effects for me included pain in the left side/stomach area; tenderness in the same area; diarrhea for two days after the last dose."

5 / 10
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  • Anonymous
  • January 18, 2012

Esomeprazole / naproxen for Osteoarthritis "No more diarrhea. Excellent pain relief. Vimovo is great."

10 / 10
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57 Report
  • Anonymous
  • January 24, 2012

Esomeprazole / naproxen "Unfortunately, I believe that Vimovo may have caused severe gastrointestinal problems. SEVERE heartburn, diarrhea, nausea, bloating, bad taste in mouth."

4 / 10
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42 Report
  • Pan...
  • Taken for less than 1 month
  • January 24, 2021

Esomeprazole / naproxen for Osteoarthritis "Took 1st and last Vimovo pill. Helped with pain, but a few hours later had bad diarrhea and a night of stomach pains. Not going to proceed with a 2nd pill."

2 / 10
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10 Report
  • Ano...
  • September 9, 2016

For Osteoarthritis "Gave me the worst diarrhea I have ever experienced and terrible stomach pain after taking 2 tablets. Still suffering 3 days later."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.