Spravato User Reviews & Ratings (Page 3)

• Fir...
• Taken for less than 1 month
• November 23, 2020

For Major Depressive Disorder "Had my first Spravato treatment today. The high feeling lasted about 45 minutes. It felt like my legs were separated from my body. I felt really happy. Coming down was not very fun. I started to feel sad again. I’m not giving up though. Going to keep going."

• MIS...
• October 31, 2020

For Depression "I have mixed feelings about this drug. This has taken the suicidal thoughts and squashed it. My depression is very little. I really don't like the treatment - feeling spaced out for 45 mins. I've had high heart rate, dizzy, sickness, headaches. The BIGGEST most important part of this treatment is to take no medications the night before and day of treatment, don't drink the night before or you will pay for it with super sickness, panic attacks, and high heart rate. Everyone is different with this treatment, don't think it's going to be fun because it's not. But versus being dead, it was worth the try! I had to find this out on my own, the doctors don't tell you much about what and what not to do when you take this medication. Most important, put yourself in a calm state during, I found playing soft music is a must, and try not to get up during, or it will cause you to be dizzy and sick. Wait at least 45 mins after when it wears off. I hope this helps someone."

• Spr...
• Taken for 1 to 6 months
• December 6, 2019

For Depression "I think people who are taking Spravato should read the wealth of information from the maker. I have severe anxiety. It does not assist with anxiety. If you have a doctor giving you Spravato for severe anxiety, that’s insane! Spravato is for depression only. Take the dose, relax, and you absolutely want to be alone, lights off, and listen to music YOU LIKE. Do not sit in a lighted room with the clinician. They will come and check on you. I do not recommend you bring a family member while the medication is working. If you can stand, go to the bathroom if you have to. If you can’t stand, ask for help. Having to use the bathroom takes the entire process of reprogramming your brain away. Urination - yes, it is more difficult on Spravato. Going #2 - You're not supposed to eat food at least 2 hours before taking meds. Is it worth it? Yes! Does it last forever? No, but as I get more and more doses, it is working longer and longer. I hope this helps someone else."

• RFM...
• Taken for 1 to 6 months
• December 2, 2019

For Depression "An update from September: I've been on Spravato for over three months now, and it seems to be helping, although I'm still not seeing rainbows. It works best for me about 48 hours after a visit. My experiences are all over the place. If you clean your sinuses before your visit, its effects are a lot stronger. I had some bizarre reactions. One of the weirdest was the feeling of melting into the floor and then the floor dropping out. It also causes me to have a strong urge to urinate and messes with my sense of taste. The vision issues have more or less subsided. Take some candy to the appointment, preferably Life Savers wintergreen or peppermint. Nothing you can choke on. Note: When the cost of Ketamine infusions hits $200, I'm going to switch. Pure Ketamine is amazing."

• SPF...
• Taken for 1 to 6 months
• September 3, 2019

For Depression "I'm finding repetitive transcranial magnetic stimulation (rTMS) more effective, but I'm continuing to use both together. If you want to skip the rubbish, go for straight ketamine. That stuff is amazing. It's going to cost you $$. I've used ketamine once prior to Spravato, and that was the best I've felt in 45 years."

• RFM...
• Taken for 1 to 6 months
• September 3, 2019

For Depression "I've been on esketamine and rapid TMS for over a month now, and I'm starting to see some small improvements. 84 mg gives me some intense reactions. I found that putting your head between your legs after you inject until it soaks in really amplifies the effects. I'd use regular ketamine, but my insurance won't cover it, and at $400 a visit, that's not going to happen. I got approved to use Spravato for a year when needed, and Janssen Pharmaceutical is picking up my copay for now. They have a plan to pay for your medication if needed, and $80,000 net a year or less qualifies. I'm planning on switching to rTMS by itself soon. It only takes 5 minutes and has no restrictions on my day."

• Kar...
• August 8, 2019

For Depression "I have had 3 sessions of 56 mg. First time had the most dramatic side effects, very strong dizziness and dissociation. Next day I felt great. Second session had the worst reaction. Side effects last through the evening, dizziness and nausea. Next day I felt like my head was full of mud, couldn't make any decisions, had a blank look on my face all day... didn't feel like I was in this world. And the third session seemed to be somewhere in the middle. The side effects during and the evening of weren't too bad. The next day I functioned and went to work like a typical day. I can't say I have seen relief from my depression. Dr. thinks I should still give it a few more times. But I am going through a difficult time in my life, so maybe my depression would be way worse if I didn't have the Spravato treatments?"

• Anonymous
• August 1, 2019

For Depression "So I posted that I had Spravato at the 56mg for 3 sessions but felt the same. So I am at treatment number 6 at 84mg, and I am finally noticing a difference. I used to be an avid runner and stopped and pretty much rotted on my couch since January. Well last week, I began running again and feel a bit of the depression lifting. I do not in any ways feel cured, but I do feel a little better. I am hoping with the few more sessions I will keep on improving. What I am nervous about is the efficacy of this because to have to go once a week is very expensive... good luck to everyone there is hope!!!!!"

• Art...
• Taken for 1 to 6 months
• July 16, 2024

For Depression "In case you’ve been a victim of any type of online scams, worry no more. I wish to inform you all about the chargeback experts Fla, s, h, r, e, c, la, i'm, at, gm - mail - com or Fla, s, h, re, c, l, aim, a:t, out, look - com, which has proven to be invaluable in helping me retrieve funds following my unfortunate encounter with a fraudulent scheme. Should you require assistance with financial recovery, I highly recommend consulting their services as they have demonstrated exceptional proficiency in this field."

• TLA...
• Taken for 6 months to 1 year
• October 5, 2023

For Major Depressive Disorder "I am currently in the phase of getting the medication every two weeks. I am also taking Venlafaxine and Doxepin for sleep. Overall, I feel like the medication is helping, but I developed some vertigo symptoms like random dizziness, brain zaps, and brain fog. I am also in EMDR therapy as well. I don't see a 'regular' therapist. So my experience with the sessions is great because I meditate, then I fall asleep. It's like the medication is giving my brain a much-needed break. I do have varied dips between treatment sessions, especially now that they are farther apart. I feel like I got more of a benefit in the beginning because the treatment was more frequent. I feel at odds about this because I don't want to come off as an addicted person, but it does help me. I am too ashamed to admit this to my medical team. I have emotional blunting rather than down (to me, a plus). I wish I could do the treatments at home because I am more comfortable there. I am concerned about relapses."

• pfx...
• Taken for less than 1 month
• November 29, 2022

For Major Depressive Disorder "31 y/o, I have been tried on 30 meds over the last 6 years, tried rTMS as well with no results. The only thing that's ever helped is tramadol (for MDD). I'm also on klonopin as needed. I had one Spravato treatment today. It was the exact opposite of IV ketamine, which I really didn't like and quit after 4 infusions. IV was COLD, clinical, and felt mean. Spravato, on the other hand, felt good. It felt very pleasant and WARM. I took the 84 mg. I did not 'trip' at all. I didn't on the max dose IV ketamine either. Both felt like a drop in the water compared to DXM or DMT, but I didn't want to 'get high', I want to feel less depressed. I think the klonopin attenuates it a bit. The experience was like a total couch lock. It was very pleasing. It felt like I was doing personal therapy in my mind, along with the music. I was feeling words like creativity, peace, acceptance, and seeing troubling issues in my mind, like grief and loss, and was able to breathe through them. I am excited to keep going with Spravato."

• car...
• Taken for less than 1 month
• September 28, 2022

For Major Depressive Disorder "After many months of coordinating clinicians, paid leave for hubby, and 2 insurances, I had my first Spravato treatment yesterday, and it was great. The first time I have been able to truly relax since a stalking in 2008, from which I developed PTSD. I go to a wonderful clinic with calm, serene decor, and my therapist specializes in psychedelic guidance (hubby's union insurance pays for this, my Medicare Advantage pays for the Spravato). Also, I have experience with psychedelics from when I was a kid, and I use medical marijuana, so I understand altered states. As of today, I feel the same... low mood and anxiety, with a bit of stomach upset. Tomorrow is my second session. I'm hoping this is going to help, as I am unable to tolerate most psychotropic drugs due to a gene mutation affecting my liver. Good luck to everyone out there."

• Jac...
• Taken for 1 to 6 months
• March 27, 2022

For Major Depressive Disorder "I just finished treatment #12 of Spravato today. I am 37 years old and am diagnosed with treatment-resistant depression and complex PTSD. I have been on at least 10 different types of antidepressants over the past 15 years. I have also done TMS and IV ketamine treatments in the past 5 years. I would say that I am cautiously optimistic that Spravato is starting to work. I have gone from sleeping 6 to 7 hours during the day and 8 to 9 hours at night because I did not want to face life. Now I still sleep a full night but only take a 1 to 2 hour nap during the day. So I have increased energy and an overall improved mood. I would say the biggest change has been in my suicidal ideation. I still have hard nights, but the intrusive thoughts are way less! As anyone who has been dealing with depression for years and years knows, there is no one miracle cure. I would say overall though Spravato is helping, and thankfully, unlike IV ketamine treatments, it is covered by my insurance, which is a huge blessing."

• Dav...
• December 1, 2021

For Depression "Bioavailability is a big issue with ketamine. Infusions provide 100%, intramuscular maybe 70%, and Spravato, nasally 30%+. Unless you don’t swallow for several minutes after pressurized into nostrils. As it drains down your throat, and if you don’t swallow, the membrane in your mouth allows much greater absorption, much greater. The experience is much more pronounced, which I only assume means more meds into your system and thus a better outcome. Sure seems to be working that way for me."

• DVe...
• November 4, 2021

For Depression "Have had maybe 5 Spravato treatments. Almost immediately felt better on depressive feelings associated with chronic pain. I seemed to notice the dissociative effects varied wildly from treatment to treatment and believe the stronger the effect, the more medicine gets to my brain. Today I decided not to swallow for as long as possible, theorizing swallowing what drains from the sinuses is lost to the effects of stomach acid. Well, as I swished the drainage (yeah, kind of gross, but it travels that path in any event) and avoided swallowing for as long as possible, I experienced the strongest dissociative effects to date. Makes sense as the medicine is absorbed through membranes in the mouth rather than lost to the stomach. I may be wrong, but I think the more dissociative, the more medicine gets to the brain, the more impactful the effect, the better I will feel. Will update as I continue the process, assuming I don’t drown :)"

• goa...
• Taken for less than 1 month
• October 7, 2021

For Depression "I have had Spravato three times-once with the lower dose; twice with the higher. It's difficult to leave a review knowing everyone responds differently (but hopefully with enough enjoying remitted depressive symptoms). I didn't notice anything my first two sessions, during or after. But my partner did (more positive/less irritable). On the third dose, I did feel like more color was returning to my life, but that lasted for a day. This is not unusual: the medication supposedly builds up. The post-nasal drip is foul, but I've found that some candies work the best. I don't feel actually sick (although some people do). I didn't disassociate or have any reactions at all. I had ketamine for the main anesthesia ingredient during a major hip operation, and I came out of that surgery feeling great for a week even with the pain, so I'm hopeful continued use of its sibling will really help me. There is a question about whether maintenance really does need to be ongoing to keep the benefits."

• H2B...
• Taken for 1 to 6 months
• September 30, 2021

For Major Depressive Disorder "It’s working for me. The first month wasn’t pleasant. I tried to go in with an open mind, but when nothing had happened during the third week, I felt desperate. Then, after the 6th session (third week), I was able to do some minor tasks that had seemed overwhelming. By the end of the 4th week, I felt significantly less depressed—no suicidal thoughts at all, less hopelessness, more willing to engage with the outside world. Feeling some pleasure. I’d estimate that I’ve achieved a 70% lift from one of the darkest and longest passages I’ve ever experienced. I’m currently stabilized at a higher level than what I’ve achieved after adjusting meds until I’m on a combo that works for a while. I ruminate less. I get off the couch occasionally. Most important, my head is clear enough that I can do some work in therapy. Unfortunately, Janssen’s long-term study was for maybe 8 months, so who knows how long it’ll work?"

• Mar...
• Taken for 6 months to 1 year
• April 26, 2021

For Major Depressive Disorder "September 24, 2020, started Spravato after dealing with self-hate, suicidal thoughts, depression, and rage for over 35 years. Being admitted to a mental facility and being prescribed several different medications which worsened the idea of suicide, I felt this was the last option. I am taking 3 sprays per month, and it has helped me a great deal. I take a Zofran shot before treatment and also take 2 Phenergan when I wake up the morning of the treatment to help with nausea, however, I still vomit during the session. I have tried an empty stomach, and that doesn't help either. I am very sensitive to smells now as well. The smell of the doctor's office now makes me sick to my stomach. Other than the side effects, I do think it is a good drug for me. I do seem to lose my train of thought, and if speaking, sometimes I cannot complete sentences and cannot think of words. I am a bit skeptical of the long-term affect of using this drug."

• Anonymous
• Taken for 1 to 2 years
• October 6, 2020

For Major Depressive Disorder "The Spravato nasal spray literally saved my life, and I did it for a year straight. I did end up overdosing by taking it with tramadol that I was given for pain from my third hip surgery that I had no idea would interact with. I only got to the 2nd spray before I had to spray the other into the trash to act like I used it because they refused to believe I had overdosed. I stopped going back for that unless for emergencies. It was perfectly fine for a year, and I felt as if I could live. I used to do acid when I was younger, so tripping never scared me. It is a huge experience for anyone wanting to try it, but if you're at wits end, I'd say go for it. It worked for me. Just remember that tramadol is a MAJOR interaction, and both kratom and klonopin/xanax will make the Spravato less effective when using it. Hope this helps for anyone wanting to try."

• KBa...
• Taken for 1 to 2 years
• July 16, 2020

For Depression "Spravato Let’s just say this is when you have tried everything else and you still need help. If you think this is just a way to get high, you're wrong. Although my one and only bad experience out of 40 treatments was pretty psychedelic, I just didn’t know where I was. My doctor was nervous. Otherwise, this drug has worked very well for me in certain areas. My suicidal thoughts have lessened by half. Depression down a quarter. This is a new drug so they are still working on it."

• Ana...
• Taken for less than 1 month
• April 10, 2020

For Depression "I would like to know if anyone else currently being treated with Spravato has had insomnia, flashbacks, extremely weird, and vivid dreams? I have only completed 2 treatments so far and am curious as to how it is affecting others."

• Aus...
• Taken for less than 1 month
• December 30, 2019

For Depression "Spravato has been miraculous for me. The day after my third treatment (first at 84 mg) I felt the darkness lifting. My depression score went from severe depression to mild mood disturbance. I haven’t felt normal in six years. Tried dozens of meds, and nothing. I’m still not 100%, but so much better. I don’t dread my life anymore. The crushing sadness is gone. I know everyone responds differently, but for me it’s been life-changing."

• Car...
• Taken for less than 1 month
• October 5, 2022

For Depression "I was having suicidal ideations when I got my first Spravato last Thursday. The thoughts went away until Saturday morning when I was a mess. I had my second Spravato Monday and have had no ideations back. I am still depressed, but it is working for me. I have my third treatment tomorrow."

• Bet...
• Taken for 6 months to 1 year
• March 7, 2022

For Depression "I’m happy with my results. It took me until the 4th week to feel substantially better. I’m a few months into a weekly maintenance schedule. I found the treatments somewhat unpleasant initially, but soon grew used to them. My advice: It’s not a miracle cure, so try to temper your expectations—the limited studies have shown that Spravato + a new antidepressant is maybe 30% more effective than a new antidepressant alone. Although the manufacturer contends people might feel better within days, not everyone will. It’s not a psychedelic therapy; any dissociation is a side effect—talk to your doctor about how Spravato works. The intensity of the dissociation is not an indication of how strong a given treatment is. It’s not a treatment for bipolar, anxiety, or PTSD."

• Goo...
• Taken for less than 1 month
• November 5, 2021

For Major Depressive Disorder "I complete week 4 Monday. 84 mg is super strong - can be trippy. Start with 56 mg. Do NOT drive for several hours. Do NOT move around much during the session as you could get nauseous. My depression is much improved so far. Improved, but this is not a magic bullet."