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Duloxetine for Anxiety User Reviews (Page 4)

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Reviews for Duloxetine

Commonly mentioned side effects
  • Cal...
  • April 10, 2015

Duloxetine "I have GAD, tried Celexa, worked for a while, mental fog. I then tried Lexapro which worked but I decided to try Cymbalta for its chronic low back pain effectiveness. I have a bulged disc, arthritis from home care for many years. I will not even consider narcotics for pain... Cymbalta has been a lifesaver, I too have dry mouth, night sweats, increased weight of 10 lbs. But I feel calmer, I started off on 30 mg for 2 wks then increased the dose per my HCP. I can tell when I don't take it. Chronic low back pain, dizziness as well, and anxiety symptoms return... I am a nurse and I hate taking medicine but this is one medicine I don't mind taking. The benefits outweigh everything else."

10 / 10
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  • Sha...
  • Taken for less than 1 month
  • June 8, 2017

Duloxetine "It's amazing. Zero side effects. I feel 'Normal'. These reviews scared me but my Dr encouraged me to try for myself and see. Lexapro put 10 kilos on me. Edeonax made me the sickest I have ever been in my life and was a bloody nightmare. After that ordeal, I was so scared to take Cymbalta. My energy is amazing now. Anxiety, panic attacks, and social anxiety feel mild but manageable - like I have a chance."

10 / 10
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  • xxo...
  • November 18, 2007

Duloxetine "I'm 29 & been on Cymbalta 1 week, prior to taking, couldn't sleep (4 hrs on average), panic attacks, acne breakouts, hair falling out, highly stressed, now a little disoriented at times, loss of appetite (not a bad thing), great sleep (much needed) and I'm much calmer. The doctor wants to add Wellbutrin in 30 days but I am not going that route. I am very pleased with the direction we are going in now it is just taking some time to adjust to the side effects and new routine of actually resting!!"

9 / 10
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Frequently asked questions

  • Tig...
  • Taken for 1 to 2 years
  • June 10, 2013

Duloxetine "I have been taking Cymbalta for 15 months now. First 30mg and then six months later up it to 60mg/day. It was prescribed to me for clinical depression. It works for the depression and I also noticed it has worked very well for anxiety also. My MD and I have discussed that I probably have had this anxiety disorder for some time and curtailed with the depression, Cymbalta has done well for both. Side effects are weight gain (5-10 lbs) and bad withdrawal effects if you miss a day or two - headaches. Otherwise, the medication has worked very well and I feel like I can live my life again."

9 / 10
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  • Ash...
  • Taken for less than 1 month
  • August 25, 2023

Duloxetine "I am now in the middle of week two and I am starting to feel so much better. I noticed that I am able to get out of bed and face my day. Before this medication, I would shake all over. I just wouldn’t get out of bed because I would hope that I just passed away in my sleep to finally end all of my anxiety and depression. I thank God every day that my doctor put me on this medication because I have been able to drive my car again without having a severe panic attack and I can breathe again. A lot of things that used to upset me don’t bother me anymore and I find myself laughing a lot more. I forgot what I even sounded like laughing until I got put on this medication. I finally had a breakdown and that is what made me turn to medication. Before, all I thought was I need to get put on Klonopin, but I have realized that I don’t need them. I just need the one pill which is Cymbalta, and I take one a day at 30 mg, and I can finally participate in my life again! I rarely have a bad day!"

10 / 10
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  • LT1...
  • December 4, 2015

Duloxetine "I have used Prozac (gained a lot of weight). Now I am on a combination of Wellbutrin and Cymbalta. What a difference! No foggy brain. My emotions are back. Don't feel like a zombie anymore. Feel a little dizzy at times, but the benefits outweigh the side effects. I lost 10 kg!!! Look and feel great. Will stay on this combination. Great for depression."

9 / 10
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  • Sha...
  • December 22, 2019

Duloxetine "I’ve been taking Cymbalta for 7 days for anxiety, and I hate it! Today has been the worst. I keep forgetting where I’m parked and/or where I’m going as I’m driving down the street. I will suddenly just be like, where was I going?! Also, I have been extremely paranoid. Friends think I’m on drugs that are making me twitchy and nervous, and that just adds to the anxiety. The one thing I specified to my doctor is that I don’t want to feel like I’m out of control and not myself! I’m only taking 30 mg. I’m weaning off ASAP. Thank goodness it’s only been a week."

1 / 10
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More FAQ

  • Roc...
  • Taken for less than 1 month
  • August 30, 2018

Duloxetine "I've been taking it for 10 days. On the first day, I had an upset stomach. I took it for 2 days at night, but I was having insomnia, getting only 3-5 hours of sleep. I switched to mornings and started getting 6-7 hours of sleep after 1 week. I noticed a big improvement with slight depression within the first few days (I was easily emotional several times a day). My anxiety is not gone, but it seems to be getting better already. I experienced a little dry mouth and decreased appetite (I lost 4 lbs), but that seems to be getting better each day. The first few days can be a little rough, but I'm seeing improvements, and I suggest to people to stay with it, the side effects will improve."

9 / 10
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  • Pap...
  • April 18, 2018

Duloxetine "Since my retirement, life has taken a few major turns. Deaths in the family, reduced income, children with problems, greater interaction with my bipolar wife, and aging finally brought me to a point of high anxiety. Ativan was too much, so the doctor started me on 20 mg Cymbalta. I'm still at 20 mg, and any side effects were too mild to identify. I started calling it my 'don't give a poop medicine' because I found I could deal with my wife's constant 'need' by just not caring. I just finished my taxes, and any thoughts I had of discontinuing soon were wiped away. Reading through these comments, I have seen the cluster of minor side effects that I was not associating with Cymbalta: afternoon fatigue, spaciness, headache that responds to water, unusual constipation, and a dream/wake state coupled with extended drowsiness after a normal night's sleep that can be attributed to Cymbalta. I was beginning to get anxious. Thank you all for sharing your experiences. I assure you that at least one person has benefited and is grateful."

9 / 10
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  • Ell...
  • April 11, 2016

Duloxetine "Was prescribed for depression, but it affected my panic disorder very much. I went from 6-7 panic attacks a day to 1-2 a week/month. It really helped with my anxiety. The initial 2 weeks were horrible though, increased anxiety, hot flashes. And it interacts with a lot of medications (including vitamin D supplements)"

8 / 10
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  • Rea...
  • February 7, 2017

Duloxetine "I took Cymbalta (20 mg twice per day) for about a year. The drug worked better than any other antidepressant I tried. Around 10 months ago, I wanted to see if I could come off the drug to see how I would do. I suffered from anxiety and mild depression. Once the drug was weaned out of my system, I haven't felt quite right. My doctor agreed for me to start taking it again. After three weeks, I have a much better state of mind with decreased anxiety. I really like this medication and have no side effects!"

9 / 10
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  • mo1...
  • Taken for 1 to 6 months
  • July 13, 2013

Duloxetine "I have suffered from anxiety problems my whole life, but it was easily managed until I turned 23 (2.5 years ago) when it blew up and every month got much worse. In Dec 2012, I was diagnosed with severe generalized anxiety disorder, moderate panic disorder, and moderate agoraphobia. I also have Irritable Bowel Syndrome-D, and combined with anxiety, I always had to be near a bathroom - any time I left the house I had diarrhea. Couldn't go shopping alone, do drive throughs, etc. Started this and almost immediately felt a bit better, minimal side effects (insomnia/headache 1st 3 days, itchy armpits 1st week) and it has taken the edge off lots. Have done many things I couldn't. No weight gain so far, very happy. Only big anxiety triggers bother me a bit, and Imodium use decreased LOTS! No mental fog!"

8 / 10
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  • cpb...
  • December 8, 2016

Duloxetine "After taking Cipralex for anxiety for over 6 months, I began to experience a very low mood and energy levels. My doctor recommended I switch to Cymbalta. Overall, my experience has been positive. I didn't even notice, but on Cipralex, I had a very decreased sex drive that rebounded right back once I was put on Cymbalta. I had trouble finishing the first 2 weeks during sex, but this side effect, along with decreased appetite, dissipated after the first 3 weeks of treatment. Overall, my mood has stabilized, and I feel very good on this drug. Please note that people tend to report either great or horrible experiences, and everyone reacts to drugs differently. Take reviews with a grain of salt and always collaborate with your doctor for the best results."

9 / 10
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  • Ano...
  • Taken for less than 1 month
  • June 27, 2025

"I just wanted to give my personal review of duloxetine that overall helped me tremendously in a moment of extreme anxiety (associated with fibromyalgia, head tension, rapid heartbeat, severe dizziness, etc.). At the 3rd-4th day, all the extreme symptoms of anxiety seemed to vanish little by little at 90%. But the main reason for this review is the side effects. I take 30 mg every day, and all I had was a slight to mild nausea (that at 3rd-4th day seemed to vanish little by little). Other than that, no other side effect. Benefits: no muscle pain, no rapid heartbeat (rare occasions), calmness, better judgment, more relaxed, and no nervousness. So, in my humble opinion, listen to your doctor, don't be afraid of the medication itself, and be strong if you start it. Give it some time, be patient, and if side effects bother you or persist, talk to your doctor again. So, if you have a mandatory trip somewhere and you know that you suffer from traveling nausea, you will be strong and do the trip."

10 / 10
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  • par...
  • August 26, 2015

Duloxetine "At 25, I started taking Celexa. When I became pregnant less than a year later, I noticed it not working anymore. Then after my daughter was born, I noticed a huge difference. My doctor prescribed me Cymbalta, starting at 30mg and finally leveling out at 90mg. This is the best I have ever felt and I have now been taking it for almost 5 years. A year ago, I tried to lower my dosage (through my doctor of course) and within the week, noticed a huge difference. I was more irritable, less patient, and more anxious. And when I don't take it for a few days, my head pounds, I feel nauseous, and not like myself at all. At the end of the day, the good outweighs the bad. Although I do wish they were not so expensive, how can you put a price on feeling normal?"

9 / 10
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  • Ef1...
  • August 27, 2014

Duloxetine "I started taking Cymbalta earlier this year for my anxiety. I found it really helped, but I didn't want to stay on it for long. I had a few side effects while being on Cymbalta such as night sweats, trouble sleeping, and electric pulses through my body. While gradually lowering my doses of Cymbalta, these side effects did get a little worse, however, they have completely gone now. I started lowering my doses in June, and now by the end of August, the night sweats have completely stopped, my sleeping is back to normal, and the electric pulses are very rare. When I think about getting worried or anxious now, I just remember that it's not a big deal and that if I was on Cymbalta, I wouldn't have even thought about it."

8 / 10
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  • Kml...
  • October 27, 2015

Duloxetine "I tried Cymbalta right after I gave birth and I noticed a difference within days. My mood swings before my period get very bad, and I thought the medicine wasn't working anymore, so I switched to Prozac. Big mistake. I couldn't get out of bed. I switched back to Cymbalta and am on day 2 and feel good. Never had side effects or anything like that. This has always been fast-acting and an overall good medication for depression and my anxiety."

9 / 10
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  • Chr...
  • Taken for less than 1 month
  • January 28, 2013

Duloxetine "I have been on Cymbalta 30mg for just under 2 weeks. After the first 3 days, I started feeling a lot better. It was slightly scary actually to go from feeling like your world is imploding to feeling like you want to smell and see every flower on the planet. It happened so fast. Yes, there were a lot of initial side effects from getting used to the medicine. I had the shakes, weird slowing down, odd feelings, nausea, etc., but I am doing very well on it. I went on a diet again, having gained 25kg from being on Lexapro and Seroquel for over 18 months. But I now have a low dose of Seroquel every night and Cymbalta every morning, and I am back to feeling great."

10 / 10
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  • Bin...
  • September 1, 2011

Duloxetine "Never thought I would have my life back. I can think clearer, my mind isn't racing as often, and I'm not agoraphobic. I used to have a severe phobia of driving and now I can get behind the wheel and even look forward to driving! I have tried everything: Prozac, Wellbutrin, Paxil, Zoloft, and none of them have worked for me. I have lost 9 pounds and counting, because I'm not eating out of depression and anxiety and I'm able to think about myself in a healthy light. I was prescribed Klonopin for severe attacks and found after 4 weeks of Cymbalta find no need for them. I am so grateful for this medicine!"

10 / 10
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  • bre...
  • Taken for 1 to 6 months
  • January 28, 2020

Duloxetine "I’ve been taking Cymbalta for 6 weeks. I started out at 30 mgs, then up to 60 mgs. It has not helped at all and has made my stress and anxiety MUCH worse. On top of that, I am constantly sweating. Sweat drips down my face and my glasses are constantly fogged up. The weather can be 50 degrees outside, and I’m wearing shorts and a T-shirt and sweating! My doctor has decided to increase the dosage to 90 mgs, and I must comply or else be considered a “difficult” patient. I HATE sweating and I hate being so anxious that I hate people. :( I just want my life back, and I do not see that happening being constantly annoyed and sweating like I just ran a marathon!"

1 / 10
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  • emm...
  • Taken for 1 to 6 months
  • October 20, 2023

Duloxetine "I have to give this medication 10 stars. I was going through a major time with social and general anxiety, and I requested to try this drug. I am on 30mg. It took a few weeks to work, a lot longer than previous drugs I have tried, so give it time. But by about 12-16 weeks, it dramatically helped my anxiety. Before this drug, I could barely face anyone, and everything that involved people was terrifying. Now I am working, and I am able to thrive. I do still have anxiety, but it is 100% manageable."

10 / 10
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  • Jay...
  • Taken for less than 1 month
  • March 10, 2020

Duloxetine "I nearly died taking this drug. I took one 30 mg tablet and felt like someone had hit me in the back of the head. After that, I started getting brain zaps, apparently, that’s what they’re called by the doctors in ICU. It made me feel very sick and unwell, but I thought it would wear off by 6 o’clock in the morning the next day. I called an ambulance. I was vomiting, shocking, cramping, even though I hadn’t eaten or drunk anything except for water. They took me straight into intensive care. My sodium levels had plummeted, and they put me straight in for a brain scan. I was four days in intensive care. They said another half an hour and I would’ve had a massive stroke. I was 49 at the time. The doctor said it had damaged my brain, and they don’t know how long it will take to come good, if ever. I felt alright after about a week. Never take this drug, you can die from it."

1 / 10
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  • Fem...
  • September 12, 2013

Duloxetine "Have been on this medication for 4 years for Anxiety Disorder and Fibromyalgia. Cymbalta has definitely helped with both conditions. Without it, I would be in an almost constant state of anxiety and the Fibromyalgia flare-ups would be much worse. (Found this out when I reduced the dose from 60 mg a day to 30 mg every other day, after hitting the expensive Medicare 'donut hole' last year. That reduction also caused severe depression within a month and I've never been diagnosed with depression!). My side effects include some gastrointestinal problems and 30 lb weight gain, despite daily exercise and diet. (All SSRIs cause weight gain for me). Hate the extra weight gain, but it's better than having Anxiety/Fibromyalgia pain."

8 / 10
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  • Chr...
  • Taken for 2 to 5 years
  • April 21, 2019

Duloxetine "After being diagnosed with depression as a result of chronic neck pain, my doctor prescribed 30 mg of Cymbalta. The Cymbalta helped with the depression, but it also erased my ability to feel... anything. As I turned into an emotional zombie, my wife grew tired of being with an emotionless spouse and threatened to leave, with our children. Through pure luck and a misunderstanding, my wife called the police, believing I was preparing to take my own life. The police took me to a hospital for evaluation. During the interview, the doctor learned about my use of Cymbalta and took me off it immediately. I got my emotions back and my family back. I will never touch the stuff again."

1 / 10
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  • Lon...
  • July 12, 2016

Duloxetine "I'm on at this time 1 mg alprazolam 3× a day. And Cymbalta 60 milligrams once a day. Ever since I started taking the Cymbalta, my anxiety, my mood, my pain, it all feels way better. I used to take 8 or as many as I needed bars a day for my anxiety. Finally got into a psychiatrist, I was so freaked out that they were going to prescribe me Xanax for anxiety because doctors are so blah blah blah about it because people screw it up for people like me that need it. Well, the Cymbalta lowered my Xanax use basically in half. I think it's really more mental on my part, and the Cymbalta has been really good for me. I had one time that I went off of it for 2 days because I couldn't make it to the pharmacy, and yes, my anxiety came back in full-blown anxiety."

9 / 10
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