Diclegis for Nausea/Vomiting of Pregnancy User Reviews

• Mam...
• September 11, 2018

"I have hyperemesis gravidarum (HG)! Have had it with all 6 pregnancies. My last pregnancy (my 5th), my doctor gave me Diclegis, and it changed my whole pregnancy experience! In my previous 4 pregnancies, I suffered for 5-6 months, constantly puking, weak, fatigued, can't get out of bed, can't keep food or water down. In fact, I have been hospitalized with every pregnancy for dehydration and was admitted for 3-5 days where they pumped me up with Phenergan and Zofran (other nausea meds). I would feel a little better, but the nausea was never gone! After my first dose of Diclegis, I immediately felt a difference! Let me be clear, this is the only thing that has ever really helped take away the vomiting and nausea EVER. I've tried everything! During my 5th pregnancy, when I started taking Diclegis, it was the first time I felt relief. I am now pregnant with my 6th child, and I have started Diclegis again because at 6 weeks I'm so sick with nausea and vomiting I can't get out of bed!"

• Aug...
• Taken for less than 1 month
• January 25, 2020

"When I was originally prescribed Diclegis, I was told to take 2 at night and my Zofran in the day as needed. After 3 more visits to the ER, my doctor changed the dose from 2 to 4 a day. One in the morning, one in the afternoon, and the 2 at night. This was the ONLY thing that worked to end my 24/7 nausea. It does make me super sleepy at times, but I'll take that over constantly feeling like I'm dying ANY DAY. Feels good to be able to enjoy a glass of water and a snack without fear of vomiting and having stomach acid come up."

• van...
• June 3, 2013

"I have always had horrible morning sickness. This time around, I am pregnant with twins, and it was much worse. I started the medication, and it stopped the ache of nausea all the time! The bad is it did stop the nausea, but I had no signs when I was going to throw up. So you randomly throw up without knowing your stomach is upset... not fun at all. The bad thing is the co-pay with my insurance was $160, so very pricey, but worth it."

• kso...
• Taken for less than 1 month
• March 24, 2015

"I want to throw a ticker tape parade for the manufacturers of this medicine. It changed my life. I'm 13 weeks and was flat on my back, gagging all day, every day. I tried all the tricks, and nothing worked until I tried this. I am back in the land of the living and hoping to regain the 10 lbs I lost in the 1st trimester. I did a lot of research, and there is nothing that indicates that this medicine causes any problems whatsoever for the baby. It is probably the best-researched medicine on the market to date. Emily Oster's book, Expecting Better, has a nice explanation for why it was pulled in the US (but not UK or Canada) for 30 yrs."

• Yme...
• October 30, 2015

"I was completely disabled by my nausea. I had zero appetite, simple tasks seemed impossible and went 2 weeks without working. At approximately 7 weeks my doctor prescribed Diclegis. I must say I was extremely hesitant, but after another week of constant nausea, I decided I would give in. The change has been miraculous. I can sleep better, have an appetite (limited to salty or sour things only), and nausea is almost completely gone. After a few weeks of taking Diclegis, I decided to test not taking it one night and spent a full day in bed with nausea and not being able to eat. Later that night I took my 2 pills again and the next day felt absolutely wonderful. This medication is a lifesaver."

• Bri...
• Taken for less than 1 month
• January 16, 2017

"I was given samples of Diclegis to help with my all-day sickness. It seems safe, so I was pretty excited to take it. The first night I took 2 pills, and the next morning, no nausea, but I was dead tired, had a dry mouth, and had stomach aches. Literally felt like a zombie, couldn't drive, barely made it out of bed. I had to stop taking it because I can't miss work. The next day, I had a severe migraine, never had one prior. It could have been due to me stopping the medication or it wearing off, but I couldn't see nor function. I'd rather deal with the nausea than the side effects, honestly. I feel bad but cannot function on Diclegis. Pregnant women are already tired, we don't need to add to it. I'm glad it's working for others, but thought I'd share my experience."

• Hum...
• Taken for 1 to 6 months
• May 17, 2019

"Okay, so last time I wrote a review (2019-04-25), I was just put on Diclegis, and my review might not move some people, but today, after taking it for one month, I can say, girls, if you are pregnant and you have nausea, then you deserve this medicine. Ask for samples if you want to give it a try before buying, and please, if Unisom and Vit B6 doesn’t work day one, it won’t ever work on you. I wasted two weeks on it. Also, if Reglan made you sick like it did to me, throw the pill and ask for Diclegis, and I'm sure it will help, but above all lies help of God. I thank him that I can have this medicine and be happily pregnant."

• Bri...
• Taken for 1 to 6 months
• December 16, 2017

"So I suffer from hyperemesis gravidarum (HG) (severe nausea and vomiting). I was prescribed Zofran with my first pregnancy, and the birth defects that were listed that could affect my baby affected my baby. I was so angry and upset with my doctor for telling me it was safe to take. My daughter now has a heart defect. Second pregnancy, I suffered so much more than my first. I found a new OBGYN, and he prescribed me Diclegis. I will say this: it’s a lifesaver. I was vomiting 20-25 times a day, and the nausea never went away. I couldn't drink or eat anything, I lost 15 lbs in 3 weeks. This drug is the only thing that is safe during pregnancy, and it was the only drug that works. I would only recommend this to anyone that suffers from HG."

• My...
• Taken for less than 1 month
• August 15, 2017

"This drug has saved me from going insane because of how ill I was. I suffered from severe nausea and vomiting in pregnancy. Throwing up for weeks on end, I would throw up every few hours. I went days without being able to keep anything down, including water. Those who suffer from NVP, I know your suffering... it is so awful! I was stuck on the couch and in bed for over a month, and then I finally decided it was time to go on medicine. My quality of life was 0 before this medication. This medicine is definitely on the spendier side but worth every penny if you are suffering. If this medication didn't exist, I would no doubt be in the hospital."

• LRO...
• July 13, 2016

"This medicine was a lifesaver! I had horrible morning sickness and took it beginning in my second trimester up until the day before labor! I'd get horribly sick without it. My daughter turned out perfectly healthy."

• Anonymous
• January 16, 2019

"This medication was a lifesaver. I went to the ER twice with dehydration from severe vomiting. I couldn’t keep any food or water down. I was diagnosed with HG and sent home with a prescription for Diclegis and Zofran. I did not take the Zofran, but took the Diclegis religiously. It didn’t stop me from feeling ill right away, but it took the edge off and I could continue to work. I was still nauseous but able to eat again. After a month on the medicine, I was gaining weight (after having lost 15 lbs of prepregnancy weight), and I was eating like a champ! Yes, this medicine does make you EXTREMELY tired, but I’d rather fight the day tired than throwing up. (25 weeks and still taking it because I’m still sick)"

• Pas...
• June 21, 2016

"I have always been sick with each pregnancy and was put on Zofran. It worked sometimes. I have been taking Diclegis for about a month, and it works the same as Zofran for me. Sometimes it works, other times it doesn't. I am up to four pills per day. Sometimes I still throw up and feel nauseous - like today. I guess the best thing for me is to get my tubes tied. I can't deal with this whole pregnancy thing ever again. I know one thing for sure: this is the very last pregnancy for me."

• Hou...
• Taken for 1 to 6 months
• May 17, 2015

"I am thirteen weeks pregnant and have been taking this medicine since 6 weeks. At first, I didn't notice any difference, but one day my nausea disappeared. Completely! I thought that the medicine had nothing to do with it since I was sick for two weeks while taking it. Three times I have forgotten to take it and spent the following day puking. This medicine has given me my life back. I have two younger kids at home, and I don't have the time to be sick."

• Car...
• May 15, 2017

"My first two pregnancies, my doctor said I had HG. I popped all blood vessels in both my eyes and was so desperate and miserable not keeping anything down. My third pregnancy, my doctor finally told me about Diclegis! What a lifesaver! I no longer had to have a Zofran pump in my stomach or walk around my house with an IV pole! The first dose, I was tired, took a nap right away! The next few days, I was tired too. But I had to take 3-4 a day every day until I delivered my baby. So the tiredness wore off. I could drive and function just fine after taking it for a week or two. I'd rather be tired than have black eyes, look like a zombie, not be able to keep down an ice cube, and cry 100 times a day. If you're really suffering, this is worth it!"

• Bar...
• January 18, 2017

"This is my 4th pregnancy. I've always had bad morning sickness with each pregnancy but always ended by my 10th week. I started the Rx at 7 weeks and tried stopping at 13 weeks but experience terrible withdrawal symptoms. I only take 1 pill at night. When I tried stopping the med, I violently threw up, nauseous all day, body aches, and excessive sweating. I would have never started the prescription if I knew stopping it was this painful."

• Cha...
• August 12, 2016

"I was prescribed this medicine for my morning sickness. I haven't been able to get out of bed since I found out I was 6 weeks pregnant. This medicine does help me to not feel nauseous, but the side effects are terrible. I feel as if I've been given a heavy sedative. I started with the prescribed dose of two pills at bedtime. When I woke up the following day, I could barely lift my head off the pillow and was in and out of strange drug-induced sleep all day. I tried taking the medication again but only taking one pill. The effects were the same, and I felt like I was on heavy drugs. I tried for a third time but only a half pill. Same outcome. Can't get out of bed, foggy, and in and out of sleep."

• 2nd...
• Taken for less than 1 month
• August 24, 2014

"I'm 4 months along with my second child. This pregnancy is very different from the last. I never had such bad nausea, vomiting, and dry heaving. I'm taking this medicine on an as-needed basis. So far, I need one pill at night and another about mid-morning. The original prescription said one in the morning, one in the midday, and two at night. I did that once and slept until 2 pm the next day. That's not healthy either. The only complaint I have is the cost. It ran $178.53 for us. A cost that wasn't expected, but when Phenergan and Zofran aren't working.... you give in. Just as every OTC or prescription, there are side effects. For me, the benefit outweighs the risk. Try to stay away from medication until at least 13 weeks."

• Col...
• August 3, 2015

"I lost 15 lbs due to nausea and vomiting since my 7th week of pregnancy. I was vehemently against taking any medication, but after I researched this medication, I felt that it was as safe as a medication can be during pregnancy. I was at risk of losing my baby due to the significant weight loss, so I am grateful for this safe, completely effective medication. It is working for me at the lowest dose, and I feel I should buy stock in the company selling this wonderful drug. I am able to eat, drink, and maintain a normal lifestyle after weeks of misery. I highly recommend this drug if the traditional methods of managing NVP are not effective for you. I was lucky enough to receive samples from my OBGYN, so I cannot say anything as to cost."

• Raj...
• Taken for 1 to 6 months
• July 8, 2015

"I started taking Diclegis at 7 weeks (was totally against medicine, but the nausea was unbearable). I was so glad I did try it because it worked like magic. Huge difference the following day if I didn't take it at night. It also helped with my moodiness and oversensitivity to smell. 11 weeks later, I am discontinuing use of it - hoping I can manage the symptoms myself. I did not get side effects at first, but about 9-10 weeks into taking it (16-17 weeks of pregnancy), I started to lose sleep at night and stay tired all day. Since not taking Diclegis, I can sleep at night now. I think my body just got used to it and started to react with hyperactivity. Also noticed reduced fetal movement while taking it versus not."

• Ala...
• Taken for 1 to 6 months
• February 1, 2016

"I had morning sickness since I was 8 weeks pregnant. I had my first ObGyn visit at 12 weeks. In 4 weeks, I lost 11 lbs. :-( I felt miserable. I did not know there was medication to prevent nausea. My doctor prescribed Diclegis. I started 2 pills before sleeping, 1 pill in the morning, and another in the afternoon. It was magic and amazing. When I reached 20 weeks, I started feeling sick again, nauseous and dizzy, and shaking. I thought maybe I was doing overdose. I went down to 1 pill at night to sleep and I feel GREAT ALL DAY!!! Amazing... And I am currently 26 weeks and I still use it because I skipped one day and I felt horrible. Tip: if you skip or miss a pill at night, take one at any time and you will feel better. I love Diclegis."

• SSa...
• Taken for 1 to 6 months
• May 3, 2020

"When I was around 6 weeks pregnant, I was vomiting NONSTOP. It got to the point where I could not even hold down water. The doctor prescribed me Diclegis, and it has been a MIRACLE drug. I take two tablets at night before I go to bed (caution that it does make you very sleepy), which I find an added perk because it helps me get a full night's rest. There are some mornings where I wake up still feeling slightly nauseous, but I am not vomiting, so the occasional slight nausea I can deal with. If you’re looking for something to make the 1st trimester nausea/vomiting disappear (or almost disappear), look no further because this is the drug for you."

• meg...
• January 2, 2016

"This is my first pregnancy and have been in the hospital twice, and I'm only 8 weeks. I have never been so sick in my entire life, one day I vomited for 16 hours every 15 minutes. Finally, this was prescribed to me, and I started the night I was discharged, and I have not even felt sick one bit. I was doing over-the-counter B6 and Unisom, but it did not seem to work for some reason. This pill is amazing, and I would recommend it to anyone else who is suffering as badly as I did."

• Lyn...
• September 8, 2015

"I have been so sick since becoming pregnant, vomiting several times per day. Initially, I was given Zofran, but the minute it would wear off, I'd start vomiting again. My doctor switched me to Diclegis a few days ago and I feel great! No vomiting, no nausea, and I'm not worried about the potential problems that extended use of Zofran could cause anymore."

• Bec...
• Taken for 1 to 6 months
• January 23, 2020

"I had pretty bad morning sickness starting around my 6th week of pregnancy. I got to where I dreaded waking up the next day because I knew I’d be super nauseous and sometimes vomit. At my first appointment at 8 weeks, I told the doctor I was experiencing nausea and vomiting, and he prescribed me this, and it’s an absolute godsend! Taken at bedtime, I felt much better the next day! You don’t have to worry about this drug because all it is is a high dosage of Vitamin B6 and Unisom. I’m now 27 weeks and still taking it every night because I’ve been feeling good and am scared to stop it and be sick again! Lol. I tried stopping it early in the 2nd trimester but promptly vomited throughout the day, so I plan on continuing to take it because my doctor said it is safe to do so."

• Fir...
• Taken for less than 1 month
• July 16, 2015

"I have been taking Diclegis for 2 weeks now, and I feel amazing. Taking 3 pills a day seems to be the magic dose for me. I previously tried Zofran, which helped minimally, but I was still nauseous and vomiting violently a few times throughout the day. I work full time, so I really needed something more effective, so my doctor recommended I try Diclegis. Two thumbs up, just a little pricey."