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Doxycycline for Urinary Tract Infection User Reviews

Brand names: Vibramycin, Monodox, Adoxa, Doryx, Oracea, Doxy 100, Avidoxy, Acticlate, Doryx MPC, Doxy-Caps, Targadox, Morgidox, LymePak, Mondoxyne NL, Doxy-D, Oraxyl, Alodox, Adoxa Pak, Adoxa TT, Adoxa CK, Uracil Okebo Doxy 200 …show all brand names

Rating: 6.5

Doxycycline has an average rating of 6.5 out of 10 from a total of 42 reviews for the treatment of urinary tract infection. 52% of reviewers reported a positive experience, while 31% reported a negative experience.

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Reviews for Doxycycline

Commonly mentioned side effects
  • Emu...
  • Taken for less than 1 month
  • September 1, 2018

"I was prescribed this medicine for UTI. So far (day 3) my UTI pain has gone down a lot. If you’re like me and you research every detail of a medicine before you take it, please listen to me. I have extremely bad anxiety and I’ll think I have tons of symptoms after I take my medicine but it’s just my anxiety. Take a deep breath. Take some probiotics, eat (if it is with food) and then take your antibiotics and you’ll be fine. Get some rest and drink water. This medicine gave me no symptoms. Stop researching! Everyone’s different, just because someone had a bad experience doesn’t mean you do!"

9 / 10
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354 Report
  • Rei...
  • Taken for less than 1 month
  • January 19, 2021

"The two side effects that always got me while taking doxy were the feeling of nausea and having diarrhea shortly after taking the medicine. For the nausea, I would just eat and it would pretty much immediately go away. Anyways... I did a 10-day course because I noticed burning in my urethra while peeing and the need to go to the restroom very often, and after about the 3rd or 4th day, the burning was gone but it took until about the 7th or 8th day for the urgency to pee to go away. I’m an adult male, 6’1, 230 lbish, and I took a 100 mg dose twice a day, usually 12 hours apart. Hope this helps!"

9 / 10
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131 Report
  • ric...
  • Taken for less than 1 month
  • August 28, 2013

"I had a severe urinary tract infection and walking pneumonia, and doxycycline saved my life. I had 8 seizures back to back due to the serious infections, and they tried keflex first, but it did not work. Doxycycline is awesome, and I'm alive today because of it!"

10 / 10
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274 Report

Frequently asked questions

  • Eri...
  • Taken for less than 1 month
  • December 8, 2018

"I noticed my urine had a very strong, pungent odor to it, was a little darker than normal, but no pain or problems urinating. I googled 'why does my urine smell so pungent'. The response was a possible UTI (Urinary Tract Infection). I purchased AZO urinary tract infection home self-testing Test Strips at my local pharmacy, and the results were positive. My doctor prescribed Doxycycline Hyclate 100mg. Within 3 days, the color and odor of my urine returned to normal. I continued to take my prescription as prescribed for the next 7 days, took another AZO self-test, and the results were negative. This drug worked for me; no side effects."

10 / 10
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116 Report
  • Ste...
  • Taken for less than 1 month
  • February 18, 2020

"I took doxycycline with food and a large glass of water both morning and night. I had no side effects whatsoever - no nausea, vomiting, headache, etc. I felt symptom relief after just 1 day. While I’m sure others may have had different experiences - don’t let that deter you from trying!"

10 / 10
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87 Report

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  • Col...
  • June 3, 2013

"I have a severe urinary tract infection, which has also affected my left kidney. Although this medicine makes me sick every time I take it, it's in my system long enough to keep it there. It is the worst medicine to ever have to take, but I have to say it is probably doing its job! I still have 4 days of it left, wish me luck, but I would recommend this to anyone who has a serious infection. I have been on 3 other medicines before this one, ciprofloxacin included, and none of them even touched it! It's worth the sickness sometimes for a healthier life!"

10 / 10
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  • sma...
  • Taken for less than 1 month
  • March 2, 2017

"Started taking these at lunchtime. By nighttime, the pain I previously experienced in my urinary tract had subsided a great deal. Had me cured by the end of my treatment. Didn't experience any headaches or stomach problems. Top notch."

10 / 10
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99 Report

More FAQ

  • Eli...
  • July 6, 2016

"I battled a nasty UTI for over a month & went through 3 different antibiotics till my doctor finally gave me this one. Makes you terribly sick to your stomach but in the end is completely worth it!! Felt completely back to normal in 2 days!!"

7 / 10
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89 Report
  • sve...
  • March 28, 2016

"I suffer from an eye inflammation disorder, and am on doxy for life, so when I had a UTI recently, I just upped the dosage. I thought I would share a few of the more common side effects with you. First is Nausea - if you shock your system with it (Doxy is a VERY powerful broad-spectrum antibiotic) by taking too much too quickly, you are likely to get lightheaded and nauseous about an hour after taking it - symptoms persist for another hour or so, and then goes away. The best bet is to spread it out but with a lower dose - 50mg 4 times a day is just as effective as 100mg twice a day, but causes MUCH fewer symptoms. Secondly - this WILL destroy your natural gastrointestinal flora and after 3 days or so, you will get looser stools and your gas will be BAD."

10 / 10
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82 Report
  • Anonymous
  • Taken for less than 1 month
  • September 30, 2017

"I love this antibiotic, it helps my UTI brilliantly. I have suffered with UTI infections for over 60 years, yes, 60 years, and have had every antibiotic going in that time. But remember, you must take it on a full stomach if you experience side effects that affect your stomach."

10 / 10
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63 Report
  • Anonymous
  • March 23, 2009

"This medicine helped my severe urinary tract infection after taking one treatment for 10 days. Before taking this medicine, I was on Cipro and sulfonamide antibiotics to treat my urinary tract infection, 4 times without success."

10 / 10
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114 Report
  • Chr...
  • Taken for less than 1 month
  • August 27, 2020

"Can I just say if you experience a reaction to doxycycline, you do not continue taking a medication, you speak to your GP. All drugs have side effects, these negative comments might dissuade someone from taking this medication. In 9/10 people, it is perfectly safe."

10 / 10
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31 Report
  • dba...
  • Taken for less than 1 month
  • May 5, 2013

Doxycycline "Prescribed for both my urinary tract infection and sinus infection at the same time. I am a vegan and am finding it a bit difficult to time my dosage (2 a day) around other medicines and meals. I believe it is causing headaches and nausea. I have not vomited but feel as if I could. In the middle of the cycle of prescription-hope I can tolerate the remainder."

6 / 10
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75 Report
  • sct...
  • Taken for less than 1 month
  • June 28, 2021

"At 47, I started having to get up every night while sleeping to pee and was told by PCP that I was just getting older. Then I was prescribed doxycycline 2 1/2 years later for bronchitis, and almost immediately the nightly ritual of peeing 1 or 2 times has stopped completely, and I'm getting full nights of sleep once again."

10 / 10
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23 Report
  • jac...
  • Taken for less than 1 month
  • January 10, 2020

"Prescribed for urethritis (an inflammation of the urethra gland). Medicine generally works well; I did have some issues with my blood pressure increasing (normal for me is about 128/85, the doxycycline caused it to go up to about 145/90, but this appears to be temporary). Don't have any pain in my urethra as of now; still have 7 days left on the medication!"

8 / 10
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28 Report
  • But...
  • Taken for less than 1 month
  • February 25, 2023

"My doctor first prescribed nitrofurantoin. He sent my urine out to be cultured, and I had two bacteria in my urine. Nitrofurantoin only treated one of the bacteria in my urine. My doctor then prescribed doxycycline. The doxycycline got rid of my UTI and was great. The instructions say to take it with food, which is what I did. I didn’t have any nausea or vomiting."

10 / 10
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13 Report
  • ano...
  • Taken for 5 to 10 years
  • November 7, 2017

"Doxy works very well for me - no matter for what condition - but it makes me feel sick if I take it with dairy. I used to take it with yogurt. I learned to avoid dairy, +/- 2 hrs before and after the med, and I don't have problems anymore. Hope this helps. There is another trick. I have taken Doxy made in Europe, and I never had any side effects - even when taken with yogurt. I have no explanation for this."

9 / 10
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34 Report
  • Rya...
  • May 3, 2020

"I took a two-week course of doxycycline because I had pain in my testicles, the doctor assumed it was a UTI or kidney infection. Within a couple of days of taking the drug, I noticed I was having some serious mood swings (would only notice upon reflection of what I had said to people). Then came extreme sun sensitivity (ended up with pretty bad sunburn and eczema, mostly on my fingers and hands) and fairly regular tingling in my hands and joint pain in my knees and elbows. I also have serious sensitivity and pain in my fingertips (especially if I tried to squeeze something to pick it up). Now, about a month and a half after finishing the course, I have noticed pain in my joints again and the most strange thing for me is that my thumbnails are falling off and some fingernails' connection to my fingers is starting to recede. On the other hand, I basically had no problem with testicular pain straight from the first dose of the drug."

1 / 10
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27 Report
  • Pai...
  • Taken for less than 1 month
  • June 7, 2013

"I was prescribed 100 mg/2x a day for 7 days to treat pelvic pain/UTI. It worked, but a couple of days later, the UTI returned. The doctor prescribed a second week of 100 mg/2x a day for an additional week. During that week, I experienced fever, chills, severe headache, confusion, major nausea, and vomited twice. I went to Urgent Care tonight because it feels like a pill has been stuck burning my throat for 3 days. The Urgent Care doctor acknowledged swollen glands and raw, bright red throat and tested for mono and strep-both tests came back negative. So now I'm home, still in pain, without any answers, just a large medical bill. If you must take doxy, be aware of the possible side effects."

6 / 10
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72 Report
  • Tam...
  • Taken for less than 1 month
  • January 31, 2021

"Scariest experience in my life, and I've been septic twice before, so that says a lot! After finishing a week of doxy, I had trouble with wheezing, then diarrhea, then massive attacks of high blood pressure and heart rate. Felt like a heroin overdose...two trips to the ER with zero help. Day 10 of bad reaction, I'm still scared to be home alone with my kids. Allergist thinks it was a drug-induced vaso-vagal response...BEWARE!!!!! NEVER again!"

1 / 10
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16 Report
  • Anonymous
  • October 15, 2009

Doxycycline "Took a ten-day dosage for urethritis (similar to UTI), and it did not cure it - though some symptoms went away. My friend also had it, though, and it worked fine for him. I recently changed to Ciprofloxacin, so hopefully that will have better results."

4 / 10
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48 Report
  • Tat...
  • Taken for less than 1 month
  • February 24, 2018

"My dose was 100 mg every 12 hours for 4 days. Full recovery. Marked changes began within 5 hours of the first dose. Nervous that readers here are making decisions on self-medication (which is not uncommon in a poorly insured but educated US). This is the oral drug of choice for Borrelia (Lyme) infection; a stealth bacteria in the circulatory system; those who are unknowingly Lyme infected may react quickly and badly to this drug, as it turns loose antigens (from dying Borrelia) that suddenly may be dealt with by an already heightened immune system. Review 'Herxheimer' (Herx), which is diagnostic for Lyme IMHO. Treatment must continue unabated every 12 hours for at least 3 weeks for late-stage patients, and be followed by daily IV Ceftriaxone for another 5 weeks with consultation of a Lyme Literate Physician."

10 / 10
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23 Report
  • mis...
  • Taken for less than 1 month
  • December 17, 2019

"This was my second time on the med. The first time, I had no issues at all. Prescribed 100 mg twice a day. This time, I had nausea, dizziness, severe headaches, and worst of all, non-stop panic attacks. I do have anxiety issues but rarely ever have panic attacks, so this scared me big time. My doctor pulled me off after Day 3 and said my infection was likely gone since the side effects went away, and a week later, I have an infection again."

1 / 10
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20 Report
  • Eve...
  • December 11, 2016

"Was on this medication for chlamydia, and it worked great, was symptom-free after only 2 pills (1 day). This medication did not work when I got a UTI. I took 4 pills (2 days), and my symptoms actually got worse!"

3 / 10
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37 Report
  • Jus...
  • November 2, 2017

"This is the 4th time taking this in two years, and it does make me sick (it's for acne and UTI). Upset stomach, etc. But I can’t really take the other antibiotics, they give me hives and fast heart rates. The most disturbing thing I’ve noticed the last 2 times using doxycycline: I’ve had breakthrough vaginal bleeding, and NO, I’m not on birth control and have very regular periods when I’m not taking doxycycline. It normally takes a while for my period to go back to normal after I take them. Anyone else had this issue?"

5 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.