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Doxycycline for Skin or Soft Tissue Infection User Reviews (Page 2)

Brand names: Vibramycin, Monodox, Doryx, Oracea, Adoxa, Doxy 100, Acticlate, Targadox, Mondoxyne NL, Avidoxy, Doryx MPC, LymePak, Okebo, Doxy 200, Doxy-D, Oraxyl, Doxy-Caps, Alodox, Morgidox, Adoxa Pak, Adoxa TT Adoxa CK Uracil …show all brand names

Doxycycline has an average rating of 6.0 out of 10 from a total of 51 reviews for the treatment of Skin or Soft Tissue Infection. 47% of reviewers reported a positive experience, while 31% reported a negative experience.

Reviews for Doxycycline

  • Brandon
  • Taken for less than 1 month
  • September 26, 2018

"This medicine wasn't so effective for my staph which is why I can't give it a good rating. However, for those of you who are worried about side effects, I experienced absolutely none. I took with a big meal and 12 oz to 14 oz of water. I also was very careful to remain upright (didn't lean back or lay down) for at least 2 hours after ingesting. The doctor recommended that if I experienced nausea that I should take a pill called Gravol one hour before. Luckily I didn't need it. For reference, Amoxicillin slightly messed up my lower stomach after about the 3rd or 4th day (probiotics did help) and Azithromycin gave me slight nausea about 45 minutes after ingesting so it's not like I have a stomach of steel or anything. It seems people who post reviews are are mostly those who had a bad experience which is understandable. But for those who are worry like I do, it was absolutely fine."

3 / 10
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  • Broken...
  • Taken for less than 1 month
  • February 25, 2020

"Was given this doxycycline for Cellulitis in my leg, (4th time I've had Cellulitis in the same area). I had various side effects, ie headache, stomach cramps, metallic and bitter taste,= ( like radio therapy!) vertigo, and it didn't get rid of the cullulitis. Had to have a further course of another antibiotic. Side effects settled down after 5 days, course was for 7 days. There was some improvement after 5 days but no cure of the condition. One can only speak as one finds."

2 / 10
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  • dswmu...
  • Taken for less than 1 month
  • June 27, 2022

"BEWARE. If your child is taking the drug, please watch for changes in moods or emotions. This drug has a commonly unlisted side effect of SUICIDE and THOUGHTS OF DEATH. I had these feelings even thought i've never, ever, been like that in my life. Thats after only 6 days of taking. It took me nearly 8 days after taking for the symptoms to clear up. Do not take unless necessary."

1 / 10
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4 Report

Frequently asked questions

  • lisa...
  • Taken for less than 1 month
  • June 4, 2014

"I took 2 doses. The first had no side effects. The second brought extreme nausea. It's the first time I vomited in 30+ years, including when I had food poisoning. This was followed by dizziness and headache, though those could have been from all the retching. I discontinued it."

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  • Taking...
  • July 12, 2016

"At her dermatologists suggestion I have been giving my wife who has dementia this product for 3 weeks. After 3 weeks she manifested serious side effects. Feeding her 2 X a day went from 1/2 an hour to 2-3 hours for each meal. She also became very sleepy during the day and required two naps a day of two hours. Fortunately I have two live in nurses to care for her as feeding her became a full time job. While we still go out for half hour walks every day since going on Doxy she is very tired when we return and has to go to sleep by 8:00 PM. I can no longer read to her or watch TV. I have cut back to 1 tab a day with omeprazole 40 MG until the Doctor calls me back with a different antibiotic. I will provide more details soon."

5 / 10
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Are you taking this medicine?

  • Anonymous
  • Taken for 6 months to 1 year
  • October 24, 2021

"Took doxy for 8 months after round of IV antibiotics for 8 weeks after a bad prosthetic joint infection. I didn’t really have much problem with it that time except for bad sun sensitivity would burn quickly. After the 8 months my infectious disease (ID) doctor said it was clear to stop it. Well 10 days after stopping it I was in ER with sepsis in hip. Long story short after being in hospital for a while and another 6 weeks of IV antibiotics I was put back on doxycycline again this time will be on it or equivalent for life . But this round of it has made me very nauseous, bloated, and vomit easily. Tried everything can think of doing for the sickness . Dramamine helps though . Still for me I can’t stop it for now, hopefully can get ID doctor to prescribe something easier on me if there is. But it’s better than the alternative"

7 / 10
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  • Lisa
  • Taken for less than 1 month
  • November 11, 2019

"I took the medicine doxycycline for 3 days and could not handle side effects of weight gain. The scale started moving upward immediately and I was not eating any differently. My digestive track slowed down. It reduced the boil I had on my skin but I stopped taking it and asked my doctor to switch my antibiotic. I now am prescribed cefuroxime."

5 / 10
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More FAQ

  • Glow-...
  • May 16, 2018

"I was prescribed this medicine for a skin infection caused by MRSA. Yesterday was my 4th day of taking the capsule and within minutes I was retching my guts out. I am a cancer survivor, and even with aggressive chemo I never threw up! I also experienced extreme loud ringing in my ears for several minutes. And I notice that I feel very tired on this drug.Well, that's enough for me...I'm Out!!!"

2 / 10
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  • aew
  • Taken for 1 to 6 months
  • June 10, 2018

"After 5 years of specialists and numerous treatments I was prescribed Acticlate, which was a miracle drug. Without insurance it went up to over $1000. I tried the cheaper Dava brand doxy-hycl and it is useless, my condition is 4x worse than without and drug at all. Why can those of use who want a real medicine have to pay a weeks salary to get it?"

1 / 10
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  • Rayg
  • Taken for 1 to 2 years
  • December 30, 2021

"My Dr prescribed doxycycline 100mg for 20 days twice a day for self diagnosed peri oral dermatitis. My Dr says it’s rosacea, but either way the doxycycline worked well. I tried EVERY cream, salve and lotion on the market and it did nothing. It does cause me horrible stomach upset unless I eat at the moment I swallow the pill. Usually 2-3 pieces of toast does the trick. The treatment works within just 3 or so days but I continue the course as directed. It does come back tho. This time I made it 8 months between treatments and the break out lessens each time. I hope one day it will work for good. It flares up especially in the winter and with daily mask usage at work. Doxycycline is the only treatment that has worked so far even tho the result is somewhat temporary. I’ll take it regardless just to clear up my face!"

10 / 10
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  • ABee
  • Taken for 1 to 6 months
  • September 20, 2020

"I was on Doxycycline 100mg twice a day for 2 months for perioral dermatitis. During this time, I had horrible burning skin on my face and scalp. I also was very sensitive to sunlight and had bad nausea after taking it for an hour. It did clear my perioral dermatitis though. 3 months later, my hair started coming out. I do not recommend this antibiotic if you can avoid it. It has caused many issues for me."

1 / 10
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  • Doxic...
  • Taken for 1 to 6 months
  • October 15, 2021

"I have major cellulitis in both legs. I have been on many antibiotics both IV and oral. This is the only medication that has shown a longer term improvement. The swelling, redness, and open wounds are noticeably better. I take 100mg in A.M and 100mg in P.M. Have been on Doxycycline for several months. My legs have improved immensely! Do not recline or lay down for at least an hour after taking doxycycline. I have occasional upset stomach, but I now take it with a meal and have less problems. Drink plenty of fluids. Also, I have gained some weight. Overall I am very satisfied with the medication. I have not been hospitalized with my legs since starting this medication! I give it a 10 out of 10!"

10 / 10
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  • Soano
  • Taken for less than 1 month
  • October 4, 2019

"I was prescribed this after my other antibiotics didn’t fully clear my sinus infection. Because my first antibiotic I ended up getting fluid in my ear causing vertigo and was prescribed this. Every time I take this I instantly feel like vomiting, I have taken it with and without food and still feel horrible nausea and vomiting right after. After I vomit I feel fine. This is the only antibiotics I have taken that makes me vomit. Though it is one of the most common side effects. I can’t wait to get done with this round of antibiotics and hopefully it clears up my ear."

4 / 10
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  • Miket
  • Taken for less than 1 month
  • February 24, 2021

"I had first course eight tablet at a dose of 100mg per day. That did not clear up the redness and pain from my little toe below the nail. So got a further 8 x 100mg today by prescription. It is a bit easier but not sorted yet. Hope second course clears it up. I am using Brulidine cream also."

6 / 10
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  • Betty
  • October 1, 2017

"I am taking doxy (capsules) along with clarithromyin for almost 2 months now because of a skin infection. The first day I took the cocktail (had to take both twice a day) I got a headache so strong that I couldn’t put my head on the pillow. I asked the dr and told me to take the doxy alone to see if there were any changes. As I started to take it alone, I did no feel the headaches any more so I incorporated the clarithromicin but with a two hour difference. In my second month, the pharmacist gave me tablets instead of capsules and I cannot stand them! Nor alone or with the clarithromicine whatsoever. Headaches are horrible! Stop taking them. I’m not really sure if it was cause of the change from capsules to tablets though."

1 / 10
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  • NoVa
  • Taken for less than 1 month
  • August 18, 2021

"Took a 7 day course for an infection I got on the outside of my nose after having a nose vein removal by laser (tech didn't do it right, resulting in 4 ulcers--never go to anyone but an M.D. ! Lesson learned). I was very hesitant to take this due to all the risks and reviews, but I'm so glad I did. My nose has almost completely cleared in the 7 days of dosing. Only side effect I had was headache. I took it religiously with 2 pieces of toast or a PB&J, and never laid down for an hour after taking. No stomach issues at all. I'm super grateful for this drug and very happy I stuck with it! The only reason I rated it an 8 is because of the headaches, which were more of a nuisance than anything. But also because I had to avoid calcium (per the insert), and this meant skipping vitamins because I'd forget to take them middle of the day. But I guess this is my problem, not doxy :)"

8 / 10
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  • Anonymous
  • June 26, 2022

"I’m not sure what to think of this drug. I have reoccurring bouts of perioral dermatitis and the 1st time I was prescribed doxycycline 2 times a day for 10 days, then 1 a day for 30 days. Right from the start I was nauseous and had to have it with food. I suffered through the side effects of red, puffy face if I had a glass of wine, and it pretty much went away for about 3 years. Now it’s back and it took me 4 months just to get the courage to do this whole thing again. I’m on day 7 and had to take an antihistamine yesterday as I guess I was out in the sun too long…. Sometimes I just think it would be easier to live with the red rash around my nose…."

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  • Canad...
  • Taken for less than 1 month
  • August 9, 2021

"I’ve been on 100mg of Doxycycline a day for almost 30 days now, it’s for perioral dermatitis which was not going away. I take it right after dinner every night, drink lots of water before bed, and also eat yogurt with added probiotics every morning. I’m constantly nauseous and almost always have a mild headache unfortunately, but PD is such a nightmare I will continue taking Doxycycline until I’m out. I almost forgot to take a pill one night, so I had it right before bed and what a big mistake! I had heartburn for 24 hrs afterwards and was more nauseous and had a worse headache. So be careful! I can’t imagine taking this on an empty stomach. My skin currently looks amazing, so hopefully my PD stays away after this, I sure don’t want to feel this awful for a month again."

8 / 10
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  • Conce...
  • Taken for 1 to 6 months
  • July 24, 2022

"I’ve been on this med for 5 weeks now for a post surgical preventative as part of my incision line is not closing and is draining - tried it with and without food - no difference in decreasing the nausea. Finally asked the doc for zofran based on a consult with my pharmacist. This has eliminated the nausea and vomiting. Looking forward to being off this as I’m contributing my fatigue and lightheadedness to this med."

5 / 10
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  • lilpro
  • May 5, 2008

"I found the medication to be very effective however it did cause nausea."

7 / 10
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  • Anonymous
  • June 12, 2008

"Very good and effective antibiotic. No adverse side effects."

10 / 10
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33 Report
  • JNbbbbb
  • January 10, 2016

"I took doxy for contact dermititis, it cleared it up. But I am experiencing vaginal dryness as well.. Is this normal? Like the lady before said I also assume this is part of the drying out process."

9 / 10
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18 Report
  • Anonymous
  • December 6, 2009

"I have been on and off of this medication since Feb 08. My skin infection keeps coming back."

5 / 10
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25 Report
  • sick...
  • Taken for less than 1 month
  • September 9, 2015

Vibramycin (doxycycline) "After ten days my open wound is slowly healing"

7 / 10
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14 Report
  • Mous
  • August 19, 2016

"your skin will clear up while ur on this drug. This drug will screw your gut bacteria so when u stop takin it, ur acne will come back way worse. Avoid this drug at all cost."

1 / 10
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11 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.