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Dexedrine and Depression: What Users Say

Depression: mentioned by 3 users (2.4%)

Based on user experiences from 123 Dexedrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 18.7%
insomnia 7.3%
tiredness 4.9%
dry mouth 4.1%
irritability 4.1%
headaches 3.3%
memory loss 3.3%
brain fog 2.4%
depression 2.4%
fatigue 2.4%

Reviews for Dexedrine

  • Ric...
  • Taken for 1 to 2 years
  • April 16, 2023

For ADHD "I have a positive experience. I was running around with anxiety, depression, and panic attack. I was on all kinds of antidepressants, then my doctor put me on Dexedrine, the best thing that ever happened to me."

10 / 10
Was this helpful?YesNo
16 Report
  • Lco...
  • Taken for 1 to 6 months
  • March 25, 2016

For ADHD "Dexedrine is okay! When I first took it, I was excited and hoped to feel something. I was instantly in a good mood, more focused, and patient. However, the come down off this drug is horrible. The depression and sadness start to come back, and it's just discouraging that only a medication can band-aid those emotions. I have felt overstimulated as well. I had a gastric bypass four years ago, so my doc said no XR, but he put me on four 10 mg a day, which I feel is too much. I become agitated, irritable, paranoid, panicky, crying, etc. I decreased it to two a day. I feel that this might be too strong of a stimulant for me. I want to try Adderall since it's cheaper on my insurance and it has less dex. We'll see what he says at my next visit."

5 / 10
Was this helpful?YesNo
15 Report
  • Lco...
  • Taken for 1 to 6 months
  • March 25, 2016

For ADHD "Dexedrine is okay! When I first took it, I was excited and hoped to feel something. I was instantly in a good mood, more focused, and patient. However, the come down off this drug is horrible. The depression and sadness start to come back, and it's just discouraging that only a medication can band-aid those emotions. I have felt overstimulated as well. I had a gastric bypass four years ago, so my doc said no XR, but he put me on four 10 mg a day, which I feel is too much. I become agitated, irritable, paranoid, panicky, crying, etc. I decreased it to two a day. I feel that this might be too strong of a stimulant for me. I want to try Adderall since it's cheaper on my insurance and it has less dex. We'll see what he says at my next visit."

5 / 10
Was this helpful?YesNo
15 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.