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Premarin User Reviews & Ratings (Page 3)

Premarin has an average rating of 7.5 out of 10 from a total of 78 reviews on Drugs.com. 68% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Premarin

  • son...
  • July 16, 2009

For Oophorectomy "In 1971, I had surgery and was put on 1.25 Premarin and told I must take it for life. Now, in the year 2009, looking back on all, I have to say I wish I had refused the surgery and didn't take Premarin. They didn't tell us about the possible side effects in those days, told only we wouldn't understand. I reported side effects to doctors, who did nothing. My huge stomach is finally beginning to shrink after being off Premarin for years."

1 / 10
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30 Report
  • Ter...
  • Taken for 10 years or more
  • May 4, 2020

For Oophorectomy "I had a complete hysterectomy when I was 46 yrs. old. Went on Premarin tablets immediately. On the advice of my physician, I have tried several times to wean off. Unfortunately, side effects were terrible, so I always went back on until now. I’m now 74 years old. I started weaning off a few weeks ago and am now totally off. Other than a lot of hot flashes for the first week (not bad) and now just a few here and there, I’m doing great. I don’t think it helped my bones, as I have osteoporosis and am taking Risedronate for that."

10 / 10
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12 Report
  • Cat...
  • Taken for 6 months to 1 year
  • November 15, 2015

For Postmenopausal Symptoms "I have been taking this drug for 8 months. It was helping at first, but the hot flushes are coming back more frequently now, and I'm tearing up a lot lately. I had bloods done and asked if I could take a higher dosage because the test showed I'm definitely going through the change. She said no, as it would increase my chance of breast cancer. I take 0.3 each night."

6 / 10
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19 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • September 17, 2012

For Primary Ovarian Failure "Worked great for many months. Then I started noticing my hair falling out, bladder irritation, and then the dark spots that were staying put while the rest of my summer tan was fading. It was great while it lasted, though."

5 / 10
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23 Report
  • JDa...
  • October 26, 2019

For Oophorectomy "Had surgery in 1985 due to endometriosis. Am currently 72. My dosage is 1.25. A month after surgery I was advised to take HRT 21 days on and 7 off and repeat. That left me with "PMS" during the 7 day off period. Dr advised that off time was necessary to avoid estrogen build-up. I decided to take estrogen for 5 days and 2 days off. This has served me well. Through the years for one reason or another I would try other products. BUT, I always returned to Premarin: The Brand Name. The generics I tried were always found wanting. Concerning Insurance: while I was employed the insurance was never a problem. I retired at 55 years old receiving Social Security Disability. After being disabled for 2 years one must apply and accept Medicare. Changing all coverages and in my case lessening them. Medicare Part D has been a godsend for many, but not me."

7 / 10
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11 Report

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  • O M...
  • Taken for 10 years or more
  • July 3, 2023

For Osteoporosis "I have been taking Premarin for 20+ years. It has been the best thing I could have done. I have experienced no side effects, and on stopping for a month, I was so depressed and ill that I resumed taking it again."

10 / 10
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4 Report
  • njb...
  • Taken for less than 1 month
  • October 16, 2017

For Atrophic Vaginitis "I was given this to help with Vaginal Atrophy that resulted in painful UTI like symptoms and painful sex. By the third week I got limited relief from those symptoms, but had debilitating dizziness and horrible hot flashes. This stuff took me from having had a handful of hot flashes in my entire life to 5 or 6 a night. Not taking it any more."

1 / 10
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12 Report
  • Ste...
  • Taken for 1 to 6 months
  • February 3, 2021

For Atrophic Vaginitis "Have been on premarin vaginal for about 5 months. Appeared to have no side effects with vaginal dryness but after about 4 months, hair started thinning and last month gastrointestinal issues: burping, heartburn etc."

1 / 10
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7 Report
  • Pre...
  • July 21, 2017

For Abnormal Uterine Bleeding "Was put on 1.25 mg for the constant bleeding my Nexplanon implant caused me. It didn't work & made me so sick! I am a 23 yo mother of 2. Prior to Nexplanon & Premarin, I had never used any kind of hormonal medicine. I had terrible pain in the left side of my calf, the whole left side of my body was numb, chest pain, rapid heart beat & pal palpations, shortness of breath, dizziness, unbalanced, nausea, I felt like I was dying!"

1 / 10
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11 Report
  • Got...
  • March 18, 2018

For Postmenopausal Symptoms "Experienced menopause at an early age, had extreme menstrual problems from the beginning starting at about age 8. I am told after going through much menstrual problems my whole life I have several fibroids. Hoping that after menopause they would naturally shrink. Mine grew and cause me extreme pain. Hormone therapy has relieved this pain. However side effects I think cause me anxiety and I cry easily. When I try to cut back I only take it twice a week the pain comes back which is severe. I cannot stop taking it but the cost is almost $300 of prescription for I have no insurance for this. I noticed in the comments no one else mentions it used for this problem does anyone know"

8 / 10
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10 Report
  • not...
  • February 9, 2015

For Abnormal Uterine Bleeding "I've been taking this for the past 15 years and haven't had any problems. I have an annual check up and so far, there hasn't been any concerns. I did have a urinalysis done for a quarterly blood pressure check up and there was a detection of blood in my urine. Not sure if it's as a result of taking the Premarin but, I made an appointment to go back to the doctor to follow up in 3 months."

9 / 10
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11 Report
  • Tan...
  • Taken for 6 months to 1 year
  • February 3, 2022

For Oophorectomy "Unnecessary Oophorectomy performed 2000 age 50, still having periods. Hysterectomy too, due to fibroids. Now discover that its possible to remove fibroids, leaving womb intact! Suffering terribly from symptoms, given 1mg of Premarin. Over three years I started with severe headaches resulting in projectile vomiting! I was working at the time, so came off it entirely. No good! I tried different drugs, given Climaval fantastic! felt driven, confident, marvellous. Hair and skin glowing again. So MHRA in UK remove this drug from the market. I tried many more, I am placed on Premarin 0.3 which makes me feel nauseous, appetite affected as a result, and have arthritic pain. However, I stick it out as, mentally, I don’t feel too bad. The sickness fades, I am now stuck with bloating, flatulence which is noisy and uncontrollable. Why aren’t side effects removed from these drugs?"

4 / 10
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2 Report
  • Rob...
  • October 3, 2015

For Hypoestrogenism "I had cancer twice and my ovaries are not producing hormones because of it. I'm now an adult and still have not started my period. I'm only on .3 mg and it makes me eat more and my doctor says I'm growing so it's working so far."

10 / 10
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4 Report
  • tin...
  • Taken for less than 1 month
  • February 21, 2023

For Postmenopausal Symptoms "It's been two nights since I took the first dose of vaginal cream (1/2 gram) for vaginal pain. Since taking it I have developed terrible anxiety, felt spacey all day, had a headache, and had trouble sleeping. My reflux, which was under control with pepcid, has worsened. My doctor does not think these are side effects of the medication but I do not believe that. Maybe the side effects will get better after more doses, but I am reluctant to continue using Premarin."

1 / 10
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1 Report
  • Jew...
  • Taken for less than 1 month
  • August 26, 2024

For Postmenopausal Symptoms "I just started Premarin 0.625. It works, but I feel I need a higher mg, because it works for only 4 to 5 hours. Then the burning comes back. It is working. Hope my doctor can adjust the dose. Ladies, Premarin dose is the key. Dose and strength are different for all of us. Don’t give up, work with your doctor :)"

7 / 10
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0 Report
  • San...
  • Taken for 1 to 6 months
  • March 24, 2021

For Postmenopausal Symptoms "I began Premarin cream a month ago, using a pea size amount twice weekly. It does help with peri-menopause symptoms. My estrogen got very low, I ended up with prolapses, dryness, sweating, melasma, facial hair, acne, water retention and mood swings. So, I was given the cream to help with burning and prolapse. My concern is that I still have regular menstruation and no progesterone was given to me with this. The sweats and burning are improving, but ALL other symptoms are worse! Especially acne. I’m wondering if it’s estrogen dominance, even though the estrogen is low, but the doctors dismiss these concerns and nobody will repair the class three prolapse until it’s all the way out."

2 / 10
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  • san...
  • Taken for less than 1 month
  • July 25, 2012

For Postmenopausal Symptoms "I have just started taking Premarin and I must say, the night sweats are gone along with the irritability. I have so much more energy than I know what to do with and my libido is back!"

10 / 10
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153 Report
  • Sta...
  • August 13, 2008

For Postmenopausal Symptoms "This med saved my life. I was having a hard time dealing with all the side effects from my menopause."

10 / 10
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145 Report
  • Anonymous
  • Taken for 1 to 6 months
  • April 21, 2019

For Postmenopausal Symptoms "I had problems with painful intercourse, and Premarin improved it and increased my libido."

10 / 10
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55 Report
  • hys...
  • Taken for 10 years or more
  • May 9, 2013

For Oophorectomy "Premarin is great for reduction of discomforts caused by surgical menopause, hair, skin, sense of well-being, sleep, moods, and energy levels."

10 / 10
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88 Report
  • Anonymous
  • January 18, 2012

For Postmenopausal Symptoms "No side effects at all after taking for many years. Now not freely available at my current location."

10 / 10
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57 Report
  • Anonymous
  • September 18, 2008

For Oophorectomy "I've taken Premarin for over 17 years. It is great for controlling menopausal symptoms and mood swings in early surgical menopausal patients. It is also supposed to help prevent osteoporosis."

8 / 10
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57 Report
  • Mia...
  • August 23, 2019

For Postmenopausal Symptoms "I have been taking Premarin ever since I had my hysterectomy in 2007. It works fantastic for my hot flashes."

10 / 10
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22 Report
  • Anonymous
  • February 4, 2011

For Postmenopausal Symptoms "Use after several years resulted in significant hair loss; had to discontinue due to this uncommon side effect."

7 / 10
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43 Report
  • Dec...
  • September 19, 2015

For Postmenopausal Symptoms "I have lost 80 percent of my hair. I also have had bladder problems."

8 / 10
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24 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.