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Clopidogrel User Reviews & Ratings

Brand names: Plavix

Clopidogrel has an average rating of 7.2 out of 10 from a total of 102 reviews on Drugs.com. 62% of reviewers reported a positive experience, while 20% reported a negative experience.

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Reviews for Clopidogrel

Commonly mentioned side effects
  • Rob...
  • Taken for 1 to 6 months
  • June 23, 2020

Clopidogrel for Ischemic Stroke "After the stroke, the neurologist put me on Plavix with a strict warning about excessive bleeding. I was even told not to use a blade when shaving. I had a bad stroke and a difficult recovery with all kinds of issues, but after a paper cut that bled for 4 hours and a couple of all-day nosebleeds, I asked to be taken off. The GP put me on low-dose aspirin, which has worked well for me. I feel better and bleed normally now."

1 / 10
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  • Sli...
  • June 25, 2018

Clopidogrel for Ischemic Stroke "Small stroke: The only medication I was on after Patent Foramen Ovale (PFO) Closure to fix a heart defect was Plavix and 81 mg Aspirin. I was instructed to be on Plavix and aspirin for 90 days. The first 3 weeks after PFO closure were great - no problems. Muscle and joint pain presented itself with legs feeling heavy during the 4th week along with extremities being cold. I started to become very tired and fatigued throughout the day. Knee and wrist were hurting several times a day, which continued for 5-6 weeks. Muscle pain did subside somewhat around week 9. Taste changed throughout the use of Plavix, which was accompanied by a burning mouth and tongue. During the last 4 weeks of use, my vision became very blurry with a constant low-grade headache in the back of the head. Last but not least, I experienced a tingling sensation in the face, hands, and toes during the last 2 months of use. I had an eye test, MRI on the brain, a lot of blood work, and exams by a doctor to check these symptoms out - all normal. I'm hopeful this drug worked for my PFO, but it did not agree with me at all."

4 / 10
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  • FOO...
  • April 23, 2011

Clopidogrel for Heart Attack "I didn't have a heart attack, but was getting ready for one when I had an angiogram and then had 3 stents put in my right coronary artery. I have been taking Plavix for the last month with no problems. The doctors tell me I will be on Plavix for the rest of my life. At this point in my life (64) I have a cast iron stomach. Because of the aspirin I have been taking for years (perhaps the reason I didn't have a heart attack), I bruise easily and bleed profusely. Different bodies, different results. I'll try to check back in a year and update my experience."

10 / 10
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229 Report

Frequently asked questions

  • JMB...
  • Taken for 10 years or more
  • November 7, 2021

Clopidogrel for Heart Attack "Just spent 5 days in the hospital with my father, who passed out at home from anemia caused by internal bleeding. Neuro, oncology, and gastro docs all urged that he stop Plavix immediately. We had to wait 5 days for an endoscopy/colonoscopy to clear his body of Plavix while they pumped him with iron and blood transfusions. If you are on Plavix or a loved one is, PLEASE ask your doctors about risk/benefits and internal bleeding risks regularly. Just because it helped for a specific problem at some point does NOT mean it should be a blanket prescription for 10+ years. Ask. Be annoying. Save your life or your parent's life. My father still needs more tests but will probably be on iron therapy for the remainder of his life as the damage is now irreversible."

1 / 10
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  • Mik...
  • February 8, 2013

Clopidogrel for Peripheral Arterial Disease "I've been taking Plavix 75 and a baby aspirin for 9 months now after stent placement in the back of my heart. So far, no side effects except bruising. I am 65 years old, male with heart disease. Can't take any statins because they cause too much leg muscle pain."

10 / 10
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  • old...
  • January 7, 2011

Clopidogrel for Heart Attack "I have been on Plavix for a little over 5 years. It was prescribed by my cardiologist following a vascular blockage and placement of a stent. Other than bruising and bleeding at the slightest contact, I have had no known side effects. I give Plavix a 10 because I am still kicking at 73."

10 / 10
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  • Tim...
  • September 13, 2011

Clopidogrel for Heart Attack "I have been taking Plavix from the day it came on the market because of my unique clotting problem. My heart doctor has me on both Plavix and 325 mg of aspirin once daily. When I developed atrial fibrillation, they put me on warfarin also. Then I started having bleeding problems. They took me off the warfarin and I was fine on the Plavix and aspirin, no clot problems encountered."

10 / 10
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  • Dus...
  • February 12, 2012

Clopidogrel for Peripheral Arterial Disease "After two stents and medication right leg (least obstructed) improvement in 48 hrs. Left leg pain drastically reduced and mobility returning. Sleeping better. Have been on this medication (with aspirin) for one week. Very optimistic, haven't felt this good in years."

10 / 10
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109 Report
  • Agg...
  • Taken for 1 to 6 months
  • March 23, 2024

Clopidogrel for Ischemic Stroke "I had a series of TIAs which led to the discovery of an atrial septal defect. I was placed on Plavix 75mg once per day. At first, it was hard to discern if the medication made me feel bad or the condition, but I experienced fatigue that was as bad as COVID. As time went by, I left off the Plavix for a day or two and felt much better. Now I take it at night, and while I can tell that it makes me tired, the side effects are not as bad. I do not wish to have another stroke, so I feel it's worth it."

6 / 10
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  • Mel...
  • Taken for 2 to 5 years
  • November 29, 2018

For Peripheral Arterial Disease "I have been on Plavix for about 5 years since I had a stent placed. Since I have been on this medication, my bruising is horrific. I have severe calf and leg pain. I had a complete ultrasound and Doppler done, the vascular surgeon doesn't see anything. I don't know what to do anymore. The cardiologist told me I need to take Plavix for the rest of my life. I am getting a second opinion for sure... Has anyone experienced this?"

2 / 10
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52 Report
  • Alf...
  • Taken for 1 to 6 months
  • September 15, 2019

Clopidogrel for Ischemic Stroke "I was placed on Plavix after having a stroke, it was a silent stroke, and I did not even know I had a stroke until I had an MRI and a CAT scan done. The cause of my stroke apparently was high cholesterol, very high. I was placed on a starting dose of 300 mg, then on a daily dose of 75 mg for 90 days. I am currently at the two-month mark and will be taken off of it in October. I have not even noticed that I am on this medication, other than some bruises that I have developed mysteriously on my legs that are about the size of a dime to a half a dollar and about six of them at any given time."

10 / 10
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  • lib...
  • April 30, 2010

Clopidogrel for Heart Attack "I have severe bruising on my arms from very thin skin. I have debated for a long time about taking Plavix. I started taking it 9 years ago when I had a very mild heart attack and a stent in a 90% blocked artery. There was another artery that was 60% blocked which they told me should be watched. 6 months ago, I had a heart catheter and they said the blockage was gone, and they didn't know why. My doctor said that I should continue taking Plavix, and that stopping probably wouldn't help the bruising and thin skin. So that is what I will do."

8 / 10
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  • Cor...
  • Taken for 10 years or more
  • August 14, 2019

Clopidogrel for Transient Ischemic Attack "Have been on 75 mg Plavix and 81 mg aspirin for 14 years after having a stent placed in the carotid artery. Only side effect had been easy bruising until my last shipment of clopidogrel from Dr. Reddy’s Lab. The shape of the pill has changed (now white and much larger). Now, after 30 days of use, I have very large dark purplish bruises on my forearms. Looks like senile purpura. Need to find another producer of generic Plavix!"

9 / 10
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  • Thi...
  • December 20, 2015

Clopidogrel for Heart Attack "'RCA blockage of 95% in 2013, heart attack, and 3 stents. Been on Plavix 75mg since. I am fortunate I don't hardly bleed and never hardly bruise. Wife says I got thick blood and a thick head!!! No side effects, no interactions with my other 7 meds. I had Plavix stents and was told I would have to take this the rest of my life. I'm not going to argue since my father died last month from a massive heart attack, and it runs in the family: strokes, heart attacks, and diabetes."

10 / 10
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  • ske...
  • June 24, 2009

Clopidogrel for Heart Attack "I guess it is working great to relieve the possibility of clots, for I have no sign of a clot returning. However, I am covered in bruises, and my stomach is in knots more, I feel bloated and uncomfortable. I am unable to drink even a small amount of coffee in the morning, even a few hours after having taken the dose. That being said, I have to take it for at least a year after my heart attack, so I guess I have to deal with these side effects."

7 / 10
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152 Report
  • Anonymous
  • April 4, 2011

Clopidogrel for Heart Attack "I was a heavy smoker and ate all the 'bad' foods, and then, one year ago this month (April 2011), I had a heart attack. Now, one stent later, and after one year of Plavix, I have had no recurrence. Of course, I also quit smoking (hard to do but I figured my life was worth it), changed my diet (also a hard change to make), and started exercising. I guess I will be on Plavix for the rest of my natural life but, thanks to the Plavix, that life may just be a lot longer than I had hoped for last year. As for side effects, I feel the cold a little more due to the blood-thinning properties of Plavix, but I don't think I bruise any easier than I used to, and I am not a 'bleeder,' so all in all, it's good."

10 / 10
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149 Report
  • Anonymous
  • March 12, 2010

Clopidogrel for Heart Attack "Had a heart attack on July 3rd, stent put in, put on Plavix for one month. Stent partially collapsed after stopping Plavix and was having some chest pains. Doctor put me back on Plavix and no more problems since. It sure works well for me and no side effects."

10 / 10
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143 Report
  • Cli...
  • July 25, 2013

Clopidogrel for Ischemic Stroke "I was using generic clopidogrel, and after having nosebleeds, etc. I am now back on Plavix and have had no problems since. I will continue to use Plavix. I now receive the Plavix brand thanks to the card I received from the company."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • July 14, 2012

Clopidogrel for Heart Attack "I am 30 years old. I had a mild heart attack in the first week of May 2012. I had 95% blockage. I had a stent put in and I'm taking 75 mg of Plavix and aspirin regimen. I bruise really easily but no side effects that I know of yet."

10 / 10
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76 Report
  • Sun...
  • Taken for 1 to 6 months
  • May 6, 2021

Clopidogrel for Transient Ischemic Attack "After 2 Transient Ischemic Attacks (TIAs) and one hospital stay for 3 days, I was prescribed Plavix. I had an anaphylactic shock reaction. The next day, comments from the nurses, "Wow, I have never seen such a bad reaction," and the physicians apologizing the following day for giving me Plavix. First time a physician has apologized, I realized how bad my reaction had been. If you have any drug sensitivities, I would choose something else first."

1 / 10
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  • Lot...
  • Taken for 1 to 6 months
  • December 15, 2019

Clopidogrel for Peripheral Arterial Disease "Lots of bruising and bleeding. The worst part now is hives every day, only on one side of my body. It didn’t do anything to help after stents. My legs both got worse after surgery, and Plavix didn’t stop the stents from clogging up. I keep taking it until I see my PCP next week to see what to do. The vascular surgeon isn’t much help."

4 / 10
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  • Agg...
  • Taken for 1 to 6 months
  • June 12, 2024

Clopidogrel for Transient Ischemic Attack "I began taking Plavix in the ER post TIA. My blood pressure was 205 over something, and I felt like that was driving the severe fatigue. However, I have been on it 5 months and I didn't realize until I failed to take it one day how tired it made me. I now take it at night, which helped tremendously. It still makes me somewhat tired but not the severe fatigue that was lateral with Covid. I would rather stay on and not have another TIA or another real stroke. I had one of each."

9 / 10
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  • Anonymous
  • December 14, 2010

Clopidogrel for Heart Attack "RCA blockage of 95% in 2007. Two stents (medicated). I took Plavix for eight months, then discontinued it on doctor's orders. Eight months later, I suffered stent thrombosis, and the two doctors I saw in the hospital seemed surprised I had discontinued Plavix. Another stent was inserted, and I have been on Plavix since. I jog or bike for at least an hour a day, usually more. My GERD has gotten worse lately, and I just switched from Plavix to Effient, along with proton pump inhibitors in the morning and evening."

10 / 10
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  • Bos...
  • Taken for 1 to 6 months
  • December 22, 2015

For Heart Attack "My father experienced TIA symptoms, taste disturbance, severe weight loss, nausea, pins and needles, speech difficulties, and a few hallucinations or visual disturbances over the first eight days of taking clopidogrel, with repeated admissions to the hospital. He was treated as if he had a TIA, although no evidence for it, and removed from clopidogrel for ten days, during which all symptoms ceased and he returned to normal. He then resumed clopidogrel, and the symptoms returned, but after a couple of weeks, he went into an increasing decline, with pain radiating from his lower back, depression, increasing frequency of visual disturbance, constipation, lethargy, and confusion. He was taken off clopidogrel after five weeks and all pain, loss of appetite, etc., left."

1 / 10
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  • luv...
  • Taken for 2 to 5 years
  • January 13, 2015

Clopidogrel for Heart Attack "Been on Plavix for 3 years, since I had a quad CABG surgery. Just had two additional stents put in on January 6, 2015. The first two stents were open, no clots, no tissue buildup. I do have some bruising, but not extensive bleeding when I receive a cut. Thankful to stay alive."

10 / 10
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