Clomipramine for Obsessive Compulsive Disorder User Reviews (Page 5)

• ArkEN
• April 20, 2017

"I have had severe OCD since I was 14 years old. I suffer from obsessions alone. I also suffer from Bipolar I. I was on Luvox or Fluvoxamine for 15 years and it took away most of my obsessions. After 15 years it no longer worked and it took much convincing for my psychiatrist to allow me to start on Clomipramine. I have been taking Clomipramine for 6 weeks. I was surprised at how few side effects I have. I can see well now, I couldn't see well on Fluvoxamine. Even with a new prescription I could not see a street sign. I have no problems with Clomipramine. More doctors should offer this drug"

• Nitu...
• Taken for 1 to 6 months
• December 23, 2020

"I have OCD on few thing ,which I don't want to share. My OCD was increased last year. I felt nausea and also vomit daily on getting OCD thoughts. Initially my treatment was started with Fluvoxamine low dose and it was increased to 200 mg/day. My OCD decreased to 50% , but not eliminated completely. I sill have nausea and sometimes vomiting also. After some time I had decreased fluvoxamine dose to 100 mg/day, because I was thinking I will cover up with strong will power. But symptoms had not gone, nausea was continue and sometimes vomited also. In short, my doctor kept me on 100mg/day fluvoxamine and clonil 25 mg/daily. Later on my dose fluvoxamine (100mg/day) kept fixed and clonil dose is increased to 50mg/daily. Now its just like magic, my OCD has gone about 90% gone and there is no nausea and no vomiting. My mind is also calm and working according to present situation."

• Typal
• Taken for less than 1 month
• April 10, 2021

"I started this medicine 2 weeks ago, I had been majorly depressed for about 3 years and OCD longer, it started off ok and I felt better almost a day in, this continued as I increased the dosage, I slept better I was less stressed happier and could relax in a chair which was almost impossible when depressed intrusive thoughts appeared every so often but not as severe on, it was life changing, until day 13 after taking 100mg a day for the past 3 days, I had dissociation, fast heartbeat, panic, anxiety, paranoia hallucinations, shaking, everything turns dark and I smelt a pungent varnish bark smell. I had a trip to A&E for 2 nights, the medication has been stopped and I am left in a dark strange scary place with strange perceptions. I am bed ridden and afraid to go anywhere. I hope I at least am able to recover as I was on them less than 2 weeks and just hoping I get something to come off the drug with. It is seriously brutal - it is like winning football match then suddenly dumped in a graveyard with screaming voices and strangers."

• MB1aaa
• July 1, 2014

"This was awful for me. Severe palpitations and obsessive thoughts became worse leading to insomnia with severe feelings of agitation. Was on 20mg and tapering off, now on 10mg but still experiencing awful side effects."

• DG1993
• Taken for 1 to 2 years
• March 16, 2023

"During one of the lockdowns we went through I found I couldn’t return to my flat, I had convinced myself that something terrible was going to happen. The obsessive, intrusive thoughts were debilitating. I assumed I would have to kill my self to make it stop. I was placed on clomipramine and initially the side effects were annoying but did eventually wear off. It has got me to a place in which I can actually function. I’ve been on it for several years now and am so grateful to the doctor that placed me on it."

• Ommmmii
• November 10, 2012

"Clomipramine changed my entire life. I use it for TOC. Before trying it, I used almost any medicine you can name, and none of them helped me at all. I just love it. Not only that but, at least for me, It's almost side-effects free (unlike almost everything else I tried before). My only problem is with my orgasms. My libido is very healthy, and I feel pleasure just like anybody else, but sometimes, It just take me a lot to reach an orgasm (not always, but most of the time). "

• DFran...
• Taken for 1 to 6 months
• February 28, 2016

"The first 2 weeks were kind of difficult for me. Lots of side effects and very little results. Hot/cold flashes, lethargy, tiredness, dizziness, sexual dysfunction and so on. After a month, the effects of clomipramine started to really kick in. It was effective against depression. Instead of going to bed every night hating myself and want to die, that only happened once a week. It reduced some (not all) of my OCD, particularly my obsessions. On the downside, it effectively made me bipolar. At one moment, I felt like Jesus. The other I was severely suicidal. I always had mania and depression, but not to this extent. Had to go off it. Lots of pros. Lots of cons. It works. But will it work for you?"

• harvi
• Taken for 1 to 6 months
• November 30, 2019

"I began anafranil in October. I was already on lithium and buspar. At only 25mg it cleared my head and took all the fear, pain, noise, and anguish away. I didn't have a crying spell for a whole month (as opposed to once a week or more.) As the intrusive obsessive thoughts came back, we raised it to 50mg. Everything was great until the obsessions came back again. We raised it to 75mg and I fell headfirst into a crazed depression. I could not stop crying for the life of me. All day. At home, at work. We raised it to 100mg and I ended up in the hospital an uncontrollable crying rage monster. I am so lucky I didn't lose my job. We have since reduced me to 25 again. It kind of works but not nearly as well as when I began. It's better than nothing but I have no idea why it gave me my whole life back and then snatched it away overnight????"

• micky
• Taken for less than 1 month
• December 18, 2015

Anafranil (clomipramine) "I was put on this medication earlier this year for OCD. I didn't really notice a difference other then it made me tired about a half hour after taking it. It did not seem to improve my OCD symptoms. However I do wonder if I was on a high enough dose. My doctor only had me on 50 MG and I have a high tolerance to med so I might give this another shot at a higher dosage. Also I was only on it for a few weeks I think."

• uuerh
• Taken for 1 to 2 years
• June 1, 2024

"Clomipramine has been a game-changer in my battle against OCD. Its effectiveness in reducing obsessions and compulsions has truly transformed my life. I've experienced significant relief from anxiety and regained control over my daily activities. Clomipramine has been a beacon of hope on my journey to overcoming OCD, and I highly recommend it to others struggling with this disorder."

• Think...
• Taken for 2 to 5 years
• November 12, 2015

"I had terrible OCD in my late teens and twenties. Totally life-consuming - I thought I was going mad. I suppose I was. The side effects have been difficult - long term erectile dysfunction, years after coming off the medication. And at the time, when the dose went up, sort of 'flu like' symptoms: achey, nausea, upset tummy. But it evened out. And it was really worth it. Still can't get it up properly - but I can live a life. As for cost - I live in the UK, so all healthcare is free for everyone. I paid "

• Fling
• Taken for 6 months to 1 year
• February 11, 2021

"1 year of being off of this drug and I’m still going through withdrawal. This pill may help your ocd, but it will completely screw up your body in other ways. It messed up all of my hormones and gave me the most painful hot flashes you could ever have to the point where it feels like your whole body is on fire. 14 months of being off of it and I still get at least 20 of these hot flashes every single day. On top of that I was shaking so much while being on this drug you would’ve thought I had Parkinson’s disease. STAY AWAY at all costs, the drug will screw up your life."

• Hana
• November 13, 2015

"I have had chronic OCD for the last year and a half. I tried hundreds of different kinds of medication, and it's safe to say none of them worked. After five days of Anafranil, I started seeing multiple improvements. As more days passed, the level of improvement only increased. Unfortunately, it's not without side effects. I don't eat properly, I don't sleep for more than five hours, my body trembles and I feel terribly weak, but I have this theory hat maybe these side effects play an important role in forcibly stopping you from performing compulsions."

• Allys...
• Taken for 6 months to 1 year
• July 24, 2023

"It's helping me in a lot of little ways, and as time goes on, I see how it's helping me in bigger ways too. I can't do anything unless it's perfect, so I usually end up doing nothing. But this medication is helping me take baby steps."

• Bobby...
• April 24, 2016

"The most side effects I have ever heard of. I experienced nearly all of the side effects at one point or the other over the last month and a half. I am currently bed ridden trying to get off this medicine. It's a nightmare."

• Nonar...
• Taken for 6 months to 1 year
• May 14, 2018

"This drug was the answer that I was looking for when none of the SSRIs worked for my condition. I'm still in dose titration upwards, but the 75 mg is giving me considerable relief for my symptoms. It helped when no other SSRI did. I take it along with Zyprexa and Effexor, and this combination is very tolerable for me in terms of side effects. The only thing I don't like is that I have started getting acne on my face, but I think it is from one of the inactive ingredients of the medication, not from the active ingredients. I say this because I don't believe I had this side effect when I used a different pharmacy/generic company. For anyone with a ton of anxiety (of any kind), I strongly recommend clomipramine."

• cwano
• Taken for 1 to 6 months
• April 7, 2020

"clomipramine made me gain weight which furthered my OCD compulsions, therefore, I cannot truly say if it helped me or not. The weight gain was detrimental but I did hear it was gold standard. Just not for me I guess."

• Min...
• Taken for less than 1 month
• April 15, 2020

"I’ve suffered OCD, Depression (little), but massive Anxiety, I was on Effexor-XR now the Doctor is weaning me off the Effexor and started me on clomipramine 25mg, then 50mg, tonight I start 75mg per night. I was hesitant due to the reviews, but after finding this section, I’m feeling hopeful. I don’t want to give a negative feedback, as this will be my 4 week only."

• Rachael
• Taken for 1 to 2 years
• September 17, 2021

"Saris stopped working I had up to 60 obsessions a day morphing. 1 hour toilet routine. I'd been using different ssri's for 20 years with success for OCD but for some reason none of them worked anymore. I held no hope for clomipramine at all. I'm very sensitive to drugs so they were increased very slowly. The worse side effect was dry mouth, it was like a rat had crawled in and died there but it does pass and improve. Also reading movement disorder as a side effect had me begin to be convinced I had one but I didn't believe that until they were fully working. Anyway slowly all my obsessions cleared up to the point where I can almost be the other way. I was considering many ways out of life before this started to show improvement. Now it is like I'm a slightly obsessive person with no OCD. It was a miracle for me. I was nearing the end, I had no quality of life. Give it a try."

• Leon_cz
• Taken for 1 to 2 years
• September 3, 2017

"One of the better drugs I have taken. It sure works - for me 125mg completely erased my OCD related depression and anxiety but there is a side effects price: excessive sweating, constipation and reduced libido."

• LJano
• Taken for less than 1 month
• January 9, 2020

"Felt this drug immediately when it was first prescribed to me--within a day my obsessive thoughts were gone. The dry mouth side effect went away after a week, and I appreciated the drowsiness my nighttime dose gave me. All was well until 3 weeks after starting, I suddenly could not control my bladder! I full-on peed my pants twice (luckily I was home both times) before I weaned myself off the med. I was only taking 25mg once every other day."

• Ryans...
• December 20, 2011

"We have tried EVERYTHING to deal with the obsessive compulsive disorder that goes along with the Tourettes and this has been our Savior. The OCD is not as debilitating as it once was. This has given our son back his personality and is making dealing with life a little easier. No more obtrusive thoughts and no real side effects. The older tried and tested drugs are definitely the ones more doctors should look at first. ( Tics have not been aggravated at all)."

• Anonymous
• April 9, 2012

"This medicine worked wonders; I was not as paranoid as before, and was able to eat something that had fallen on the counter and things like that (before, I wouldn't have dared). It also made my depression evaporate. Unfortunately, it also caused intense hunger, in turn causing weight gain, and gave me headaches, made me hydrated, and caused frequent urination on the flip side. I'd still recommend this medicine. I'm sad it didn't work out for me because it was really great."

• Bcat
• Taken for 1 to 2 years
• May 23, 2022

Anafranil (clomipramine) "This is the only medicene that ever did anything for my OCD. I have tried everything!! (Zoloft, Paxil, Luvox, Welbutrin, Celexa, Prozac) It does have some side effects. The bothersome ones for me are weight gain (not extreme like 5-10lbs) & fatigue. I recommend taking it at night before bed because it can make you tired. If your body can adapt to the side effects, it's worth it. Especially if you have intrusive thoughts. I have obsessive checking behaviors & I also pick my skin, which is considered the same type of disorder as trichotellomania. Anafranil helped me completely stop this. I had no desire to think about it or do it anymore it was crazy. If you have tried a lot of other things, give it a try in low doses, slowly. It will get better, little by little."

• Sailo...
• Taken for 1 to 6 months
• October 1, 2015

"I was prescribed Clomipramine for my Obsessive-Compulsive Disorder. I have found that the Clomipramine has helped a tiny bit with the Obsessive-Compulsive Disorder, but I am currently at a small dose (50mg). I find this drug causes drowsiness and insomnia at the same time, so if I take it in the daytime I am drowsy and appear "out of it" yet in the nighttime not only am I drowsy and appear "out of it" but I also can't sleep! And since I started taking these pills I have been constipated; if I pass gas while in the bathroom someone I live with would accuse me of using laxatives since the bathroom would stink when I came out - and I didn't even get to poo! If these issues do not improve soon I might stop taking them."