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Wellbutrin XL for Depression User Reviews (Page 2)

Wellbutrin XL has an average rating of 7.4 out of 10 from a total of 286 reviews for the treatment of Depression. 64% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews for Wellbutrin XL

  • Mama...
  • Taken for less than 1 month
  • March 1, 2014

"This medicine has saved my life. I was on it for several years (300 mg) and felt it wasn't helping anymore, so I quit it on my own. No problem quitting, but a few months ago began feeling hopeless due to financial problems and could not do anything on weekends but lay around in bed and sleep my weekends away. I couldn't get anything done and put important things off that needed to be done. In just the last 2 days, I can tell that I already want to get out of bed and do housework and get a shower. I didn't realize what Wellbutrin XL did for me, but I do now and am grateful I am back on it!"

10 / 10
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  • Shels...
  • Taken for 5 to 10 years
  • January 18, 2013

"I have been on Wellbutrin XL now for almost 7 years and I love it. Before starting Wellbutrin with the other medications, I felt tired, could hardly function, and could not think clearly. It was so bad that I was ready to quit all the meds and just live my life depressed. I mean, after all, I was sleeping my life away anyway so it didn't matter. So I told my psychiatrist and she put me on Wellbutrin XL. It took about 3 weeks to start noticing a big improvement. I felt energetic, I wanted to do things again, my mood has been really good, I could concentrate. It helped me tremendously in my job and I was able to start living life to the fullest and be that fun-loving, energetic person I want to be. I highly recommend this medicine."

10 / 10
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  • AunnieD
  • Taken for 1 to 6 months
  • May 29, 2015

"I've been on Wellbutrin for 6 months now for anxiety and depression, and I feel AMAZING. I've lost 30 lbs and am still losing, not through any actual work on my part. I just find that I'm not as hungry. I'm full of energy every morning and it lasts all day. I've also noticed an insane increase in libido, and I've easily kicked some bad habits without really trying, like biting my nails. It just doesn't happen anymore. I also don't have any desire for alcohol or cigarettes. For once in my life since starting this long road of antidepressants, I FINALLY feel like this is the one for me. The only negative side effects I have noticed are that my chest and neck stay flushed, and I really do have to remind myself to eat."

9 / 10
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165 Report

Frequently asked questions

  • MindyG
  • Taken for less than 1 month
  • April 20, 2023

"I have battled depression and anhedonia my whole life. I have always tried to manage it through diet, therapy and exercise. I had reached the point where I could find no joy and I was simply existing. Life became incredibly arduous and, quite literally, painful. I had zero interest in any activities, often forcing myself to participate in the things that were expected of me. The only thing that I truly enjoyed was sleeping. I finally saw my doctor and, after a long chat, we settled on Wellbutrin because I really “ wanted to want to do things. “ Fast forward to today, 4 weeks of taking Wellbutrin XL. My life has completely changed for the better. My mood is stable, I have more energy than I ever expected to, my confidence has returned after decades of struggling, I no longer feel sad in social situations and I have become more fit because I am inclined to exercise every day. I am enjoying all of the things that I struggled to get through for so long without side effects."

10 / 10
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  • Thank...
  • November 8, 2016

"I've had mild to severe depression my whole life. I was on Prozac from high school to my early 20s. When I was pregnant with my first child, I stopped taking my Prozac. A year ago, I knew it was time to get back on something because my depression was creeping back in. I spoke to my OB/GYN, and she suggested Wellbutrin XL, and OMG! So grateful that she suggested this. I started with 300mg, and now a year and a half later, I'm on 450mg. And let me be honest... losing 35 lbs because of this medication is a PLUS, especially for my depression!"

10 / 10
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Are you taking this medicine?

  • Steph...
  • April 27, 2015

"I've been battling moderate anxiety and depression for most of my adult life. I'm 24 now, and since my official diagnosis at age 20, I have tried 4 other medications (Celexa, Zoloft, Paxil, Buspar) and found that each one increased my anxiety or made me a despondent zombie. 3 months ago, my PCP put me on Wellbutrin. Let me tell you, this medication saved my life. I went from spending days lying in bed, smoking weed, having daily panic attacks to waking up with a desire to take on the day. In the few months since I've been on the medication, I've lost 30 pounds. It suppresses the urge to binge eat and provides energy for the gym. My friends said I finally seem like me again. Highly recommended if you hate SSRIs like me!"

9 / 10
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  • Gastr...
  • Taken for 5 to 10 years
  • May 20, 2017

"This medication is very activating without making me anxious. I take it for depression, but I also have general anxiety disorder and OCD. I was a little worried about taking it at first because one of the side effects indicated that it could make anxiety worse, but I didn't have that problem at all. It definitely helps with depression and lifting my mood. It's not a 'happy pill,' but it is good with getting and keeping you going and not letting depression ruin you and keep you from doing what needs to be done and living your life."

10 / 10
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122 Report

More FAQ

  • there...
  • November 14, 2013

"I've been taking generic Bupropion XL (150mg) for three days and I can already say I feel like a new person. Before, I had no energy. Other than going to work, all I could do was lay around and feel sorry for myself. In just three days, I feel more clear-headed, energetic, and optimistic... I wish I had started it sooner! The only other medication that's worked for me in the past was Adderall, but I couldn't go on taking it due to the many unwanted side effects. Bupropion has worked wonders - little to no side effects for me, other than a slightly increased sex drive and loss of appetite (though nothing compared to Adderall in that department). I've also been having really vivid dreams, which I love, since I've never been one to remember them."

9 / 10
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  • JJ - ...
  • Taken for 1 to 6 months
  • December 3, 2016

"Started out on generic XL 150mg/day taken in the morning. After 2 weeks, started seeing results; feeling great all day with occasional depression at the end of the day. Doctor increased to XL 300 mg/day. Big improvement - more energy and motivation, no problem with any side effects except for welcomed weight loss! Dropped 18 lbs in two months. Really easy to diet on this med!"

10 / 10
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  • 21855...
  • Taken for less than 1 month
  • July 4, 2019

"I would have given this a 10 but I’ve only been on it a week so far. I take one in the morning as it is time released. I am so elated though because for years I’ve been on different medications for depression and anxiety and this one has really improved my quality of life. Even after a week on the others I had side effects and it didn’t seem to help. Hoping this will continue as I feel more alive my appetite and sleeping has improved and my outlook has greatly improved. Of course, eating healthy and exercise and even your spiritual life play into this. I’ve read that different medications help different people and this one is certainly helping me hope the same goes for you have a wonderful day!"

9 / 10
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  • capta...
  • Taken for 1 to 6 months
  • December 30, 2013

"I have been on this medication for half a year. I was prescribed it for my ADHD and depression. It changed my life completely. As I have never felt so great in my whole life since I was a child. High motivation, increased energy, no suicidal thoughts, and it helped me to eat less and lose weight! I was on Lexapro for anxiety and panic for 5 years and gained a lot of weight. Also, I had some other side effects with Lexapro. Happy!"

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  • JoMar...
  • July 6, 2017

"Was taking Wellbutrin XL (bupropion) 150mg in the AM & Zoloft (sertraline) 150mg at night. There was a miscommunication at my pharmacy, so I was out of Zoloft over a holiday weekend (3 days). It was the best miscommunication ever! With solely the Wellbutrin XL, I have my old self back minus the anxiety & depression. I wake up refreshed. I have more energy. I'm not napping every day or extremely lethargic. I'm excited to exercise, my libido is back & I'm calm and happy. It also has seemed to help with my food cravings, an extra bonus."

9 / 10
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  • Hanna...
  • June 1, 2014

"I've never felt compelled to write a review for a medication before, but Wellbutrin XL saved my life. I suffered from chronic depression for years before I started taking Wellbutrin, and within weeks, it was as if the rain stopped, and there's nothing but clear blue skies and sunshine since. Seriously. I cannot say enough good things about this medicine. The great thing about Wellbutrin (I take 150 MG) is that it doesn't make you feel zombie-like at all. I feel like a brighter, happier version of myself. I also take 150 MG of Lamictal, which has also significantly helped as well. I highly recommend these medications to anyone suffering from bipolar depression. They have done wonders."

10 / 10
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  • OnThe...
  • Taken for 6 months to 1 year
  • February 21, 2017

"I have been on 150mg XL for 6 months now. I was prescribed it because of the death of my teenage son and also the end of a relationship. I was diagnosed with moderate depression. I felt like a zombie with very little motivation. I always work out and have managed to stay active, but still, things were not right. I went on this, and it has made all the difference. I will agree there is apathy while on it. The highs are not as high, but the lows are not as low. You just have a quiet balance in your life, and it does not feel like you are on any sort of medication. I attempted to go off of it and could already tell I felt sad, so trying another 6 months. I did not lose any weight, but I am pretty thin already. Wonderful medicine for me."

9 / 10
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  • Alexa
  • Taken for 1 to 6 months
  • August 26, 2020

"After taking Lexapro, I gained weight. Did not take anything for more than a year until the depression relapse began. The doctor prescribed Wellbutrin. The first 3 weeks there were bouts of anger. Waited for it to pass. Then began daily tears, and dark thoughts. The condition is worse than before taking the medicine. I gave up and after a few days - another person. I do not recommend it. It was a terrible experience for me."

1 / 10
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69 Report
  • Your...
  • February 19, 2014

"I started 150mg of Wellbutrin XL in Jul 2013 due to feeling very unmotivated, depressed, tired, and hopeless. After a few days, I felt good, and by the second week, I felt better than I had in several years. I increased the dose to 300mg in Oct because I was starting to feel down again. It helped a lot but by Jan I was very irritable, angry, and bitter, so I lowered the dose to 150mg and restarted 40mg of Prozac, and the anger subsided. To address some side effects: inability to fall asleep (went away after 2-3 weeks), increased libido (awesome), pretty much the same appetite (no weight loss or gain), vivid dreams (sometimes disturbing), more emotional (but not crazy or extreme), constipation (moderate to severe), sensitivity to caffeine (must avoid)."

7 / 10
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  • nosaint
  • August 2, 2019

"I have ADHD and depression, that's why Wellbutrin was prescribed. I think my depression was caused by taking Ritalin, first-line ADHD medication. I started off with 150mg XL. The first two weeks were hard, I had a lot of the side-effects: severe headache, very dry mouth, sleeplessness. I sticked through it and noticed I become a lot more positive. If I had a setback it'd still effect me, but for not as long as before. I noticed that I had more perseverance, more energy too. I had severe brain fog, and it started to go away. But exams were coming and 150mg didn't did the trick to be able to study well, so we upped my dose to 300mg. I had to adapt again. Many of the side-effects came back but sticking through it was the right thing to do. My concentration become much better, and I become more disciplined and ambitious in my goals. I started to clean my room up, planning and preparing things. I noticed it felt like it came from myself, not from an external stimulans as with Ritalin."

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  • BigFan
  • December 4, 2008

"Wellbutrin was a miracle drug for me. The first time I ever remember experiencing 'normal' was after I started taking it. The only side effects I had were having vivid, movie-like dreams, and losing a ton of weight. The dreams were so great, I didn't want to wake up, and the weight loss was a dream come true."

10 / 10
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  • TM123
  • Taken for less than 1 month
  • November 3, 2015

"Wellbutrin XL 150mg for 3 weeks. This medication has changed my life. Went to PMC to renew Ritalin prescription after Adult ADD diagnosis. Family history of depression, PTSD (combat-related). Personal history of adolescent drug and alcohol abuse (nothing hard). Held a firm belief depression could be 'powered through'. Apparently, depression has set in at 33, which I treated with Adderall and Ritalin. My drinking got so heavy I fell and suffered a serious concussion. Doctor denied my Ritalin script and prescribed Wellbutrin. Had side effects: severe bloating, headache, pressured speech. All gone. Energy is sky high, focus is on point, and weight is down. Can't say enough about this medication. Hope it stays this amazing forever."

10 / 10
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120 Report
  • Sadie
  • February 6, 2019

"I have been taking 150mg Wellbutrin XL for 4 months now and it has changed my life. I have had depression and anxiety since childhood. I took Celexa for about a year in my late teens and it left a bad impression on me regarding antidepressants (it relieved my anxiety but made me extremely sedated and robotic). After several years I finally gave into trying antidepressants again, as I had just lost my job and was struggling to get out of bed for class. Wellbutrin has helped me feel energized, less foggy, less irritable, but mostly just... normal. Insignificant inconveniences no longer feel like catastrophes. Self esteem is slowly coming back. Sleeping better. No longer crying everyday. Can keep up and be present in conversation. Also, I did not experience any of the common side effects. The only thing that I experienced for a few weeks was very mild aphasia (forgetting words), but I'd take that over being depressed any day!"

10 / 10
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  • Rocke...
  • Taken for 1 to 6 months
  • December 8, 2022

"This medication saved me, I know it sounds dramatic and cliche but it honestly did. After the first 2 DAYS I noticed a difference. Funny, I didn’t realize how depressed I was until the darkness started to lift and I started feeling better. I was in so much pain mentally that I actually hurt physically, my body ached every morning. I was hurting so bad. I was tired ALL the time, I could hardly make it through the day and I was in such a dark place I felt nothing could help me but death. It was that bad. I quit smoking and drinking, started exercising and was shocked at how good I felt mentally. This might not work for you, I get that. there is NO such thing as a miracle pill, we all have to give it a 100 percent too. It won’t work if you don’t work with it, it’s an an aid not a cure. Good luck to you all. Wishing you nothing but peace and happiness. It will get better ❤️‍"

10 / 10
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33 Report
  • Dria...
  • December 22, 2015

"I am making this solely because I remember looking up reviews of antidepressants before I ever took one and being terrified of what my life might look like if I started taking one. I took Lexapro for 3 days and felt like a zombie, and swore off antidepressants. However, my depression continued. Thankfully, my roommate, who is also a 21-year-old junior in college, told me about her positive experience. I feel like a completely different person now. The first two weeks, my emotions were all over the place, and my anxiety was high. Anxiety is still a factor sometimes, but it gets less frequent every week. At 5 weeks on Wellbutrin, my life has changed for the better. I finally feel like I can live the life that I was meant to. And I've lost weight!"

9 / 10
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116 Report
  • So...
  • Taken for 5 to 10 years
  • December 23, 2013

"I was previously taking 150 mg for years and it stopped working. Just started 300 mg XL three days ago and I feel great! I suffer from mild depression and anxiety/rage. In one day, I noticed I had more energy and felt an overall feeling of hope and joy. I also have a terrible sweet tooth and noticed that it took my cravings away (I didn't expect that!). Since the holidays are here, people have been giving me chocolate and baked goods and I'm not even tempted. I feel great!"

9 / 10
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135 Report
  • Creat...
  • Taken for 1 to 6 months
  • July 12, 2015

"I've been on this medication a few times now. Gone off of it for several different reasons but nothing relevant to the medication itself. I've been on it for the third time 2 or 3 months now. I love it! I always have. It manages my depression, actually manages my anxiety and panic attacks, makes me feel content, keeps me awake during the day, has increased my sex drive and is just a wonderful medication. Works different for everyone. If you're scared to start it because of the reviews, don't be. I strongly encourage you to at least give it a try."

10 / 10
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  • Anonymous
  • October 6, 2008

"This medicine gave me back my life! I got laid off, then had to move. I used to sit in the house in my pajamas all day and not even want to go outside or do anything. I started taking Wellbutrin, and I got a job, started working out, met my new fiancée, and went back to school. That was over five years ago. I graduated from college in Feb. 2009! You are worth it!"

10 / 10
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178 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.