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Bupropion for Depression User Reviews (Page 5)

Brand names: Wellbutrin XL, Wellbutrin SR, Aplenzin, Budeprion Forfivo XL Budeprion SR

Bupropion has an average rating of 7.0 out of 10 from a total of 1285 reviews for the treatment of Depression. 60% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Bupropion

  • Steph...
  • April 27, 2015

Wellbutrin XL (bupropion) "I've been battling moderate anxiety and depression for most of my adult life. I'm 24 now, and since my official diagnosis at age 20, I have tried 4 other medications (Celexa, Zoloft, Paxil, Buspar) and found that each one increased my anxiety or made me a despondent zombie. 3 months ago, my PCP put me on Wellbutrin. Let me tell you, this medication saved my life. I went from spending days lying in bed, smoking weed, having daily panic attacks to waking up with a desire to take on the day. In the few months since I've been on the medication, I've lost 30 pounds. It suppresses the urge to binge eat and provides energy for the gym. My friends said I finally seem like me again. Highly recommended if you hate SSRIs like me!"

9 / 10
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  • Thank...
  • November 8, 2016

Wellbutrin XL (bupropion) "I've had mild to severe depression my whole life. I was on Prozac from high school to my early 20s. When I was pregnant with my first child, I stopped taking my Prozac. A year ago, I knew it was time to get back on something because my depression was creeping back in. I spoke to my OB/GYN, and she suggested Wellbutrin XL, and OMG! So grateful that she suggested this. I started with 300mg, and now a year and a half later, I'm on 450mg. And let me be honest... losing 35 lbs because of this medication is a PLUS, especially for my depression!"

10 / 10
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131 Report
  • samban
  • Taken for less than 1 month
  • June 8, 2023

Wellbutrin (bupropion) "I took two doses of 150XL bupropion, on the second dose I have immediate ear ringing, fullness, and pressure in my ears. I’ve never once had an issue with my ears in my life. I’m very young and healthy. Months later and after multiple ENTs, I have permanent tinnitus from this drug. It shouldn’t be legal."

1 / 10
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31 Report

Frequently asked questions

  • JJ - ...
  • Taken for 1 to 6 months
  • December 3, 2016

Wellbutrin XL (bupropion) "Started out on generic XL 150mg/day taken in the morning. After 2 weeks, started seeing results; feeling great all day with occasional depression at the end of the day. Doctor increased to XL 300 mg/day. Big improvement - more energy and motivation, no problem with any side effects except for welcomed weight loss! Dropped 18 lbs in two months. Really easy to diet on this med!"

10 / 10
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128 Report
  • Gastr...
  • Taken for 5 to 10 years
  • May 20, 2017

Wellbutrin XL (bupropion) "This medication is very activating without making me anxious. I take it for depression, but I also have general anxiety disorder and OCD. I was a little worried about taking it at first because one of the side effects indicated that it could make anxiety worse, but I didn't have that problem at all. It definitely helps with depression and lifting my mood. It's not a 'happy pill,' but it is good with getting and keeping you going and not letting depression ruin you and keep you from doing what needs to be done and living your life."

10 / 10
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Are you taking this medicine?

  • there...
  • November 14, 2013

Wellbutrin XL (bupropion) "I've been taking generic Bupropion XL (150mg) for three days and I can already say I feel like a new person. Before, I had no energy. Other than going to work, all I could do was lay around and feel sorry for myself. In just three days, I feel more clear-headed, energetic, and optimistic... I wish I had started it sooner! The only other medication that's worked for me in the past was Adderall, but I couldn't go on taking it due to the many unwanted side effects. Bupropion has worked wonders - little to no side effects for me, other than a slightly increased sex drive and loss of appetite (though nothing compared to Adderall in that department). I've also been having really vivid dreams, which I love, since I've never been one to remember them."

9 / 10
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164 Report
  • Meano
  • Taken for less than 1 month
  • September 19, 2018

Wellbutrin SR (bupropion) "I tried to get by on 150 mg of bupropion but was getting weepy over little things and decided to ask to up my dosage, and I am now on 300 mg (The other 150 mg in the evening). I went through waking in the night as well as during the day with all kinds of negative feelings and gut-wrenching crying. I really didn’t have side effects... I stayed away from people because I knew I was not quite 'right' and didn’t want to make a 'fool' of myself as I knew my thinking was a little askew. I just today—-24 days into the increase in medication—felt a breakthrough and feel like I have a new lease on life... it is like I was teetering on the edge and have now slipped over into normalcy."

10 / 10
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104 Report
  • Pinkin
  • Taken for less than 1 month
  • January 30, 2014

Wellbutrin SR (bupropion) "I started Wellbutrin SR just last week. I feel 90% better already. Previously I was taking Zoloft and after a year and a half, I felt sluggish, tired, hopeless, and just plain blah. I now don't have constant worrying, it helps with my OCD, and the things that bothered me before have just become basically no big deal to me. I'm happier, I focus much better. And my spirits are brighter than they have been in months!"

9 / 10
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161 Report
  • tahoe...
  • Taken for 2 to 5 years
  • October 29, 2014

Wellbutrin SR (bupropion) "I was taking this for depression for about 3 years, and it was a miracle for me. I stopped taking it when I lost my insurance for about a year. The result was a weight gain of 20 lbs and severe depression again. I've been taking it now for about a year, and the result is that I'm happy again. I lost 30 lbs and experienced an increased libido. I've never taken any other antidepressant besides Wellbutrin SR."

9 / 10
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152 Report
  • thank...
  • Taken for 1 to 2 years
  • October 21, 2018

Wellbutrin (bupropion) "I have been taking Celexa for a while to treat depression, and while helpful, it had made me very numb, and I was still feeling occasional episodes of mild depression. My provider added Wellbutrin, and what a difference! Wellbutrin gave me a boost of mental energy and feelings of well-being that I had never felt before. I am currently doing very well with the combination of Celexa and Wellbutrin. I feel better than I ever have in my life. I've been on this fantastic combination for a year. Highly recommend."

10 / 10
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102 Report
  • Skarg...
  • July 19, 2015

Wellbutrin (bupropion) "Y'all! I am one of these people who cannot say enough about bupropion! It has changed my life after only day 8. Such a subtle but powerful shift in perception and decrease in troublesome habits (smoking one of them, but also irrational anxiety getting on train, rushing down the street for no reason, rushing through dinner) has decreased by drinking, made me feel less weighed down. There are side effects the first few days, but they will go away! Stick with it, and you won't regret it."

10 / 10
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141 Report
  • Sammy...
  • Taken for less than 1 month
  • October 31, 2015

Wellbutrin (bupropion) "I'm in my early 40s and have noticed the last couple of years I've become very agitated over nothing! Always yelling at my teenager and I could literally feel my blood pressure raising over the smallest things. Also this last year for some reason I became depressed. I didn't ever want to get out of bed or leave the house to do anything. I've always had a bad opinion about antidepressants, but I knew SOMETHING had to change. I reached out to my doctor who gave me 100 mg of generic Wellbutrin, and the very first day I noticed I was calmer! I fell asleep 2 hours later but woke up refreshed. I just finished day 3, and I swear I feel fantastic! Not only have I not yelled even once, I don't feel angry at all! And I want to do stuff again. Very happy"

9 / 10
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137 Report
  • 21855...
  • Taken for less than 1 month
  • July 4, 2019

Wellbutrin XL (bupropion) "I would have given this a 10, but I’ve only been on it a week so far. I take one in the morning as it is time released. I am so elated though because for years I’ve been on different medications for depression and anxiety, and this one has really improved my quality of life. Even after a week on the others, I had side effects and it didn’t seem to help. Hoping this will continue as I feel more alive, my appetite and sleeping have improved, and my outlook has greatly improved. Of course, eating healthy and exercise, and even your spiritual life play into this. I’ve read that different medications help different people, and this one is certainly helping me. Hope the same goes for you, have a wonderful day!"

9 / 10
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91 Report
  • capta...
  • Taken for 1 to 6 months
  • December 30, 2013

Wellbutrin XL (bupropion) "I have been on this medication for half a year. I was prescribed it for my ADHD and depression. It changed my life completely. As I have never felt so great in my whole life since I was a child. High motivation, increased energy, no suicidal thoughts, and it helped me to eat less and lose weight! I was on Lexapro for anxiety and panic for 5 years and gained a lot of weight. Also, I had some other side effects with Lexapro. Happy!"

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158 Report
  • corka...
  • Taken for less than 1 month
  • August 30, 2016

Wellbutrin SR (bupropion) "I initially got put on Wellbutrin for my anxiety and depression. I'm taking the SR one once a day and I have been on it for less than a week. I have to say I have felt amazing. I am someone that is extremely active, and I had always tried to be conscious of my diet, but I struggled with binge eating. I would eat healthy for 4 days and binge for 3. I'd feel awful and start over EVERY Monday. It was really getting out of hand, honestly, and contributing to my mental state. I am 24 years old, 5'4, and my normal weight for my activity level was always 120. I got all the way up to 150 and could not understand why. In almost a week, I've lost 5 lbs, it's just falling off me now. I feel happy again and in control of my emotions and eating."

10 / 10
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  • AKTso...
  • September 2, 2013

Wellbutrin (bupropion) "The first time I took Wellbutrin I was in the hospital for major depression, suicidal ideation, and a nervous breakdown. After trying the typical Zoloft, Paxil, and others, the doctors were running out of options. A new doctor on staff gave me Wellbutrin (I don't remember the dose) and I instantly was transported to a state I can only describe as ecstasy. Unfortunately, this lasted only one day, probably because of my 'virgin' brain. But staying on this med for two years helped me recover my life. I am so grateful. This was 15 years ago, and although I still suffer from major depressive disorder, I have been able to get a Master's degree and a new career."

5 / 10
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160 Report
  • JoMar...
  • July 6, 2017

Wellbutrin XL (bupropion) "Was taking Wellbutrin XL (bupropion) 150mg in the AM & Zoloft (sertraline) 150mg at night. There was a miscommunication at my pharmacy, so I was out of Zoloft over a holiday weekend (3 days). It was the best miscommunication ever! With solely the Wellbutrin XL, I have my old self back minus the anxiety & depression. I wake up refreshed. I have more energy. I'm not napping every day or extremely lethargic. I'm excited to exercise, my libido is back & I'm calm and happy. It also has seemed to help with my food cravings, an extra bonus."

9 / 10
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115 Report
  • Charlie...
  • Taken for less than 1 month
  • July 28, 2020

"I am an Afghanistan War Veteran that suffers from PTSD/Anxiety/Depression. I have been on Escitalopram Oxalate the past year and recently switched to this bupropion at the direction of my mental health provider in the VA clinic. I rate this 9/10. My mind doesn't race anymore, I am able to stay focused, able to have longer meaningful conversations with people, have a little more motivation to finish products, and make me more in tune with other people's feelings. Like I legitimately care about people when bad things happen to them. I have been on this medication for about 1 month and have lost 5 lbs. I would normally smoke about 5 cigarettes per day and am now down to 2. And so far it looks like this is what I have been missing. Very happy with the results so far."

9 / 10
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75 Report
  • rouxb...
  • Taken for 1 to 6 months
  • June 22, 2014

Wellbutrin SR (bupropion) "I have been on bupropion for a month. I have lost the sadness, obsessive dark thoughts, and have more energy and fewer aches and pains. I felt a little weird taking it at first (mild headache, taste in my mouth) but those have gone. This is great stuff, and I feel hopeful and focused. I am not snappy and withdrawn from my spouse."

9 / 10
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150 Report
  • winni...
  • Taken for 1 to 6 months
  • June 5, 2014

Wellbutrin (bupropion) "Wellbutrin is amazing. Prior to Wellbutrin, I was put on Zoloft, Prozac, and Valdoxan, all of which either killed my sex drive, did nothing, or made me too sleepy to function. For 2 years, I stupidly went off medication and just thought everything in life was crap, and probably said some things I regret to people. Eventually, it came to the point where I was failing at work and angry at everyone. The ADHD medication I was taking also worsened my depression. With Wellbutrin, I have been on it for around two months, and I feel great. I have energy, more motivation, increased libido, and I feel content, although I still have moments. Also, I have lost more than 5 pounds without dieting or exercising."

10 / 10
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148 Report
  • CanlasT
  • August 20, 2015

Wellbutrin (bupropion) "All I can say is Wellbutrin has substantially increased my quality of life. I was so scared about side effects that I waited years to try antidepressants. I was on Celexa, and when that failed, I was put on Zoloft, which also did me no good. Wellbutrin not only brought me out of a deep depression, it's caused me to be active, and my weight is now in the normal range. I'm also more organized and positive than I've ever been. My family members, who were initially against me taking Wellbutrin, have changed their opinion because they see me enjoy life again."

10 / 10
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134 Report
  • pwnvi...
  • Taken for 1 to 6 months
  • January 25, 2016

Wellbutrin (bupropion) "I was prescribed Wellbutrin by my doctor when I told her that I was having a very difficult time getting out of bed and wanting to be productive one month ago. My doc prescribed me Wellbutrin 150 xl, which has as an added bonus made me completely stop smoking and even become repulsed by cigarettes. No negative side effects. Wellbutrin has reduced my urge to drink alcohol by 90%, and when I do drink, I feel intoxicated after only 2 or 3 drinks. I have been exercising five days a week and eating well to assist in mood elevation. I have more motivation and energy now than a month ago. I am impressed with this medication."

10 / 10
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129 Report
  • Hanna...
  • June 1, 2014

Wellbutrin XL (bupropion) "I've never felt compelled to write a review for a medication before, but Wellbutrin XL saved my life. I suffered from chronic depression for years before I started taking Wellbutrin, and within weeks, it was as if the rain stopped, and there's nothing but clear blue skies and sunshine since. Seriously. I cannot say enough good things about this medicine. The great thing about Wellbutrin (I take 150 MG) is that it doesn't make you feel zombie-like at all. I feel like a brighter, happier version of myself. I also take 150 MG of Lamictal, which has also significantly helped as well. I highly recommend these medications to anyone suffering from bipolar depression. They have done wonders."

10 / 10
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  • Anonymous
  • July 23, 2008

Wellbutrin (bupropion) "I have been taking Wellbutrin for almost a month now and I have already noticed a change. I used to be this really upbeat, happy, positive person, and all of a sudden, I was tired all the time, couldn't sleep, was really sad all the time, agitated really easily, and also got snippy with people at the drop of a hat. My mom was the one who said I needed to go see the doctor and find out what was going on with me. I've tried other antidepressants; this is the only one that works for me."

10 / 10
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205 Report
  • OnThe...
  • Taken for 6 months to 1 year
  • February 21, 2017

Wellbutrin XL (bupropion) "I have been on 150mg XL for 6 months now. I was prescribed it because of the death of my teenage son and also the end of a relationship. I was diagnosed with moderate depression. I felt like a zombie with very little motivation. I always work out and have managed to stay active, but still, things were not right. I went on this, and it has made all the difference. I will agree there is apathy while on it. The highs are not as high, but the lows are not as low. You just have a quiet balance in your life, and it does not feel like you are on any sort of medication. I attempted to go off of it and could already tell I felt sad, so trying another 6 months. I did not lose any weight, but I am pretty thin already. Wonderful medicine for me."

9 / 10
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115 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.