Bupropion for Depression User Reviews (Page 4)
Brand names: Wellbutrin XL, Wellbutrin SR, Aplenzin, Budeprion Forfivo XL Budeprion SR
Bupropion has an average rating of 7.0 out of 10 from a total of 1285 reviews for the treatment of Depression. 60% of reviewers reported a positive experience, while 19% reported a negative experience.
Reviews for Bupropion
- Anonymous
- Taken for 1 to 6 months
- January 8, 2015
Wellbutrin (bupropion) "Wellbutrin SR 150s, which initially had positive outcomes on my depression, probably the best I've tried, and I've tried a lot in the past years. It took a bit to get the optimal dose. At 300 mg, it was causing a cascade of side effects: anxiety, palpitations, sweating. Doc helped me back down to 100 mg with no side effects. The depression is just as gone as with the initial 300 mg. Wellbutrin also developed a positive outcome in mere days - a major plus."
- Anonymous
- Taken for 1 to 6 months
- April 29, 2016
Wellbutrin XL (bupropion) "26-year-old male. Been on it for 31 days. 1st week 150mg XL: high-speed energy. Mild insomnia (up till 3 am most nights). Waking early and generally good mood. 2nd week 300mg XL. Very high constant anxiety. Emotional swings. Broke down in tears one day. 3rd week: Things were smoothing out. Still slightly anxious. Less emotional. 4th week: Feeling completely normal, almost like I'm not on any medication. More level-headed and better mood with fewer swings. Anxiety disappearing and confidence growing. No side effects. This is in combination with seeking help from a counselor, and confiding with a close friend of mine about how depressed I have been over the years. I am happy I took it. It has got me back on my feet and allowed me to seek help."
Frequently asked questions
- How long does it take Wellbutrin XL/SR (bupropion) to work?
- Does Auvelity work better than Wellbutrin?
- Auvelity vs. Wellbutrin: Effectiveness for Depression?
- What Medications can help me Quit Smoking?
- Faith...
- Taken for less than 1 month
- November 27, 2021
Wellbutrin (bupropion) "I am on week 3 on Bupropion 150 SR, I went off Paroxetine cold turkey and started this. First week, I was tired all the time and had some weird nightmares that went away starting the 2nd week. Then the 2nd week, I felt awkward. I was not myself, I was very irritable, didn't want to be around people, had some headaches that week, and wasn't interested in doing many things. I was about to quit, but my doctor told me to please give it a try until week three when it is supposed to start working (from week 3 to 6). So I did with a lot of effort, and I am so HAPPY I DID HANG IN THERE!! I FEEL SO MUCH BETTER. Today is my day 22, and I at last feel peace, joy, and motivation again to do things I didn't want to do before. I am eating less, not so hungry, stopped smoking, and do not need caffeine to function as I did before. It doesn't have side effects on libido like Paroxetine. So far, it has been worth the wait of 3 weeks of not feeling so well. IT IS WORTH IT. PLEASE HANG IN THERE!! Pray for all to feel happy."
- young...
- April 17, 2019
Wellbutrin (bupropion) "After a few bouts of mild depression, I entered a more major depressive period about two years ago. I told my psychiatrist I was so sad 'my teeth hurt'. I was unmotivated, hopeless, and really just sooo sad all the time. My doctor tried to give me an SSRI but I pushed for Wellbutrin due to the lack of sexual side effects and weight gain with SSRIs. The first couple of weeks on it, I was on a total high. I remember dancing around with my kids and literally jumping around at the playground like a crazy lady. Once that levelled off I was just 'me' again. No other way to put it than I feel totally normal now. I still get sad, happy, angry (so I'm not flat) but all within a normal range. The ONLY negative for me is that if I miss a dose I turn into a raging crazy lady. I feel like I'm withdrawing from hard drugs. It definitely makes me scared of when the time comes to try and get off of it, but for now it's worth it."
Are you taking this medicine?
- Mama...
- Taken for less than 1 month
- March 1, 2014
Wellbutrin XL (bupropion) "This medicine has saved my life. I was on it for several years (300 mg) and felt it wasn't helping anymore, so I quit it on my own. No problem quitting, but a few months ago began feeling hopeless due to financial problems and could not do anything on weekends but lay around in bed and sleep my weekends away. I couldn't get anything done and put important things off that needed to be done. In just the last 2 days, I can tell that I already want to get out of bed and do housework and get a shower. I didn't realize what Wellbutrin XL did for me, but I do now and am grateful I am back on it!"
- Shels...
- Taken for 5 to 10 years
- January 18, 2013
Wellbutrin XL (bupropion) "I have been on Wellbutrin XL now for almost 7 years and I love it. Before starting Wellbutrin with the other medications, I felt tired, could hardly function, and could not think clearly. It was so bad that I was ready to quit all the meds and just live my life depressed. I mean, after all, I was sleeping my life away anyway so it didn't matter. So I told my psychiatrist and she put me on Wellbutrin XL. It took about 3 weeks to start noticing a big improvement. I felt energetic, I wanted to do things again, my mood has been really good, I could concentrate. It helped me tremendously in my job and I was able to start living life to the fullest and be that fun-loving, energetic person I want to be. I highly recommend this medicine."
- gabri...
- Taken for 1 to 6 months
- March 9, 2020
"Started with 150mg bupropion, then dose increased to 300mg. Was definitely better, but still had down days. Then, my doctor upped it to 450mg. And, boy oh boy, did it work. This is the perfect dosage for me. I haven't had a depressive day ever since. I don't feel like I am in this bad place anymore, dragging myself through life. No more excessive worry and fear, existential emptiness, lack of vitality, self-hatred, social anxiety, etc. After more than a decade, I feel like my 'natural self' on a consistent basis. I wake up feeling refreshed and looking forward to the day. I know I am finally heading in the right direction in life. I am also losing weight. No diets. I simply have no desire to overeat. The only side effect is high sensitivity to caffeine. So I have to avoid it as much as I can, or else I get anxiety. In my experience, this medication has been life-changing. There is hope, because science works! 'All this time I was finding myself. And I didn't know I was lost.' —Avicci"
- Kathe...
- Taken for less than 1 month
- July 20, 2014
Wellbutrin (bupropion) "I am on Day 3 and I am starting to notice some if not all of the effects. My mood is stabilizing and I am finding my motivation returning to me. I need it for when I get into my doctoral program! I can find pleasure in things I enjoy again. I don't have overtly pessimistic and sad thoughts as much. I'm not crying as much. Before I started taking this medicine, I was not at rock bottom, but I did not want to feel awful anymore. Depression is a real disease. The medications do help."
- nebMN
- Taken for 6 months to 1 year
- February 7, 2014
Wellbutrin (bupropion) "I was diagnosed with major depressive disorder a few years ago. I've tried basically all SSRI antidepressants. They did nothing for me other than make sex impossible, gave me leg tremors, as well as massive weight gain. I switched to Wellbutrin, and my sex drive is back to normal, my weight is dropping, and I feel a lot better. I recommend this medicine to anyone struggling with SSRIs and their many side effects."
- Janedoe
- March 7, 2020
Wellbutrin (bupropion) "DO NOT TAKE THIS IF YOUR PRIMARY ISSUE IS ANXIETY. I got on this medication because I was having trouble with anxiety and insomnia. My NP wanted to start me on Wellbutrin 150mg XL and I kept reiterating to her that I have no depression whatsoever, I’m just anxious, but she said it would help. Within 2 weeks, I was so nauseated, in a complete brain fog, my anxiety got so much worse, my heart would race, I was having panic attacks daily, couldn’t sleep, my mind was racing non-stop, and although I’ve never felt as if I had issues with depression, I was so depressed on this medication! I went from being very high-functioning with mild to moderate anxiety to completely useless on this medication. I called into work multiple times (which I had never done before - I’m a nurse). I couldn’t focus, was so disoriented, and felt like I was just floating. I stopped and feel much better after a few days and I got on a PRN benzo for anxiety."
- Miami...
- August 7, 2013
Wellbutrin (bupropion) "I am a 25-year-old woman and started taking this 6 days ago along with clonazepam for anxiety. 300 mg of Bupropion once a day (mornings) and clonazepam twice a day (once in the morning and once in the evening). I have to say that... so far THIS ROCKS. I was suffering from depression, obsessive thoughts, anxiety, and panic attacks for months. I stopped taking Zoloft after a year because I gained 60 lbs on it. Now with Wellbutrin, I have no side effects except loss of appetite and more energy. I feel more energetic, happy (almost 'giddy') and hopeful for the future. My anxiety and depression were debilitating, and this saved my life. I can't wait till the full effects kick in. 6 days in and I feel the difference."
- jaf
- April 1, 2013
Wellbutrin (bupropion) "I'm a 19-year-old college female. I was struggling with anxiety and depression for about six months and went on Zoloft in December 2012. It made me even more depressed, even though it helped with the anxiety. Zoloft also made me a zombie (napping for hours during the day, no motivation to socialize, no motivation to do schoolwork, nothing). I went off it about a month ago and switched to 150mg of Wellbutrin daily. I noticed a difference the FIRST day. It gave me the energy/positivity I have been lacking for months, and I finally am starting to feel like myself again. I recommend it to anyone who Zoloft didn't work for or who needs that extra boost to come out of a fog."
- AAnon...
- November 13, 2014
Wellbutrin (bupropion) "I was on Prozac and felt tired all the time, still depressed, and no sex drive. I thought maybe the dose wasn't enough and I was going through menopause, but the doc put me on Wellbutrin. I'm with the person above, I cannot believe in one day I felt better. I thought it was in my head. I made phone calls I would avoid because of anxiety, I got things done instead of sleep, and I felt so much happier next to my husband. Day two I woke up ready to start the day, completely the opposite of what I had been experiencing. Everyone is different, and you just have to see what works for you. Prozac is in a different class, and I just needed this antidepressant."
- Caro
- Taken for 1 to 6 months
- April 19, 2017
Wellbutrin (bupropion) "I have been taking 150 mg of the generic of Wellbutrin for the past month. I can't believe how amazing I feel! After dealing with depression for the past 4-5 years, I finally feel like myself again. I was diagnosed with PMDD and mild depression but tried to deal with both of these with Prozac and hormone birth control. After three months of Prozac, I quit. It made me tired and took away my libido. It didn't help my depression at all. I've tried three different birth controls (I'm 46... it wasn't for birth control, just to try to help my hormone levels.) Nothing helped my depression. Finally, my doctor prescribed Wellbutrin. I filled it but didn't take it for 8 months because I was afraid of the side effects. Now I could just kick myself!"
- AunnieD
- Taken for 1 to 6 months
- May 29, 2015
Wellbutrin XL (bupropion) "I've been on Wellbutrin for 6 months now for anxiety and depression, and I feel AMAZING. I've lost 30 lbs and am still losing, not through any actual work on my part. I just find that I'm not as hungry. I'm full of energy every morning and it lasts all day. I've also noticed an insane increase in libido, and I've easily kicked some bad habits without really trying, like biting my nails. It just doesn't happen anymore. I also don't have any desire for alcohol or cigarettes. For once in my life since starting this long road of antidepressants, I FINALLY feel like this is the one for me. The only negative side effects I have noticed are that my chest and neck stay flushed, and I really do have to remind myself to eat."
- Meano
- Taken for less than 1 month
- September 24, 2018
Wellbutrin (bupropion) "Have been on Wellbutrin SR 150 twice daily. BEST CHOICE I MADE!! I am a person that thrives off of happiness, feeling great, making others happy, etc! After one week, I am me again!!! HAPPY, SECURE, JUST ME!! I noticed it has helped chill me out. For those who don’t find this medication to work, maybe it is the wrong drug for your chemical imbalance. It is just a matter of finding the right drug for the right person. I'm thankful"
- Butte...
- Taken for 1 to 2 years
- October 22, 2013
Wellbutrin (bupropion) "Bupropion has been the best ad for my very difficult-to-treat atypical depression. I gradually felt improvement as my doctor increased my dosage over the course of the year. It was helping a little when I first started at 150 mg, but I felt it could do far more. It's been amazing at 450 mg, my current dose. I'm level-headed, focused, and not at all exhausted. I was so tired and wanted to sleep. It also helps me with my addiction to food as I've been captive to this my entire life. I'm slowly losing weight because I'm walking a lot more and not binging. I sleep great too, and I do not feel agitated or nervous. I don't want to consume alcohol like I used to either! It's a total different ball game than the SSRIs I've tried! I'm grateful :-)"
- AnonI...
- July 18, 2013
Wellbutrin (bupropion) "I just took the first 100mg pill a few hours ago and I feel different. I feel almost normal. I'm not thinking about being depressed, and my energy is almost back to normal. No antidepressant, antipsychotic, or mood stabilizer has ever done that! If this feeling keeps up or gets better, I don't know what I'll do. I'll probably cry tears of joy. Is this what normal people feel like?"
- Nobody
- November 16, 2014
Wellbutrin SR (bupropion) "I've been taking this medication for depression. I've been on it for about a year now. When I first started taking it, I smoked about a pack a day. Over time, this reduced my cravings for nicotine and helped me quit smoking. It took time and effort, but it worked. Also, when I started this medicine, I weighed 207 lbs, which was my highest weight. Wellbutrin caused weight loss for me, and I now weigh 165. This medicine improves my overall mood, and I am not as depressed as I was a year ago. I've also experienced hair shedding, which has become more and more of a problem. Sometimes it comes out in handfuls. I gave this medicine a 9 because mostly my side effects were positive. I don't know where I'd be without Wellbutrin."
- c3lla...
- May 16, 2013
Wellbutrin (bupropion) "This medicine really works for me and has really improved my quality of life and perspective on things. I'm 18, and I have been on this for a little over 6 months, and I would say the only bad side effect is dry mouth, but if you just drink a lot of water, you'll be fine. I like it because it has helped me stop 'binge' eating. I don't have cravings for food or cigarettes anymore, and I completely stopped smoking. I'm never tired anymore; Wellbutrin definitely gives you energy in a good way. Sex drive is completely normal, and I still have normal emotions, unlike when I was on Celexa or Prozac where I felt so emotionless. I lost 20 lbs, but I am healthy and fit and a lot happier with myself."
- Augus...
- Taken for 1 to 6 months
- January 13, 2020
Wellbutrin (bupropion) "Having fallen into a serious depression which led me to have great difficulty in doing everyday things, getting up in the morning, brushing my teeth, washing, and also couldn't get important sleep. It was getting really difficult. My neurologist prescribed Wellbutrin XR 150mg once a day in the morning. I was very hesitant to take the drug for fear of the side effects. Today, after 3 months of treatment, I sincerely thank her. I have found energy, reconnected with my social relationships, etc. In terms of side effects for me, it's mild: dry mouth, a few palpitations often at night, and slight weight loss. In 3 months of treatment, I lost 4 pounds."
- Anonymous
- March 18, 2010
Wellbutrin (bupropion) "I have been taking Wellbutrin continuously for 20 years. If it were not for this miracle drug, I would be dead. There is no doubt in my mind that my intractable depression was arrested with Wellbutrin. I have a chemical imbalance that is permanent. I once went off Wellbutrin for a month because I was taking another medicine. Within three weeks, I was having suicidal ideas. Needless to say, I will not go off it again. My doctor assures me it is safe for lifelong use."
- Lannahn
- Taken for 1 to 6 months
- May 25, 2019
Wellbutrin (bupropion) "The heightened sex drive Wellbutrin (bupropion) is so powerful that I'm even having awesome sexual dreams in my sleep. It hasn't helped me to stop smoking, but I smoke very little to begin with, so maybe that's why I don't notice a difference. It totally smoothed out my mean mood swings. I just love it. I have zero bad side effects. I do believe the medication helps females' libido more than it helps most males, but I could be wrong."
- MindyG
- Taken for less than 1 month
- April 20, 2023
Wellbutrin XL (bupropion) "I have battled depression and anhedonia my whole life. I have always tried to manage it through diet, therapy and exercise. I had reached the point where I could find no joy and I was simply existing. Life became incredibly arduous and, quite literally, painful. I had zero interest in any activities, often forcing myself to participate in the things that were expected of me. The only thing that I truly enjoyed was sleeping. I finally saw my doctor and, after a long chat, we settled on Wellbutrin because I really “ wanted to want to do things. “ Fast forward to today, 4 weeks of taking Wellbutrin XL. My life has completely changed for the better. My mood is stable, I have more energy than I ever expected to, my confidence has returned after decades of struggling, I no longer feel sad in social situations and I have become more fit because I am inclined to exercise every day. I am enjoying all of the things that I struggled to get through for so long without side effects."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
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Wellbutrin SR (bupropion) "I have ADD, anxiety, and depression. I began 100mg once a day for a week then went to 100mg twice a day. You have to give this medicine time to work. The first week I was thinking of not taking it anymore because it made me feel so tired. But I'm so happy I stuck it out! My overall mood, attitude, and outlook have improved tremendously. My mood and attention are consistent, unlike when I took Adderall and would experience crashes. This medication has made a world of difference. I'm less anxious and happier."