Pylera for Helicobacter Pylori Infection User Reviews (Page 3)

• Mr...
• Taken for less than 1 month
• September 3, 2019

"Today is my 10th and final day of taking Pylera (thank goodness). It is very powerful stuff and starts killing bacteria immediately! Unfortunately, the good ones too. The first 3 days or so, I had a lot of diarrhea, dizziness, numbness in my extremities, fatigue, and NO appetite. I was only able to eat fruit smoothies, dairy-free yogurt, and broth soups. As a result, I lost almost 15 lb of weight, and not the good kind. I had to call out of work due to my symptoms and lack of energy. Just be cautious if you take this antibiotic and get lots of rest."

• Ann...
• Taken for less than 1 month
• March 17, 2019

"I wanted to die! Nausea and abdominal pain were too severe, so I ended up in the ER. This drug is no joke. I'm on my 6th day and didn't feel any better, but worse. God only knows how I'm gonna survive for 4 more days."

• Ang...
• Taken for less than 1 month
• June 4, 2017

"I just finished my 10-day course of Pylera, and I can't believe I got through it. My side effects were bad nausea, even with food, black stools, dark urine, extreme fatigue, headache, feverish feeling, and it seems like every bit of phlegm in my body is coming out one way or another. My nose runs like a sieve, and also phlegm is running down my throat constantly. Just awesome. I feel like I've been ingesting poison and calling it medicine. I'm hoping this takes care of the infection because I've been profoundly ill for over a year, not realizing what was making me so sick until my EGD uncovered Helicobacter. The only thing I can advise is to be kind to yourself, don't expect too much of yourself, try to not work if possible."

• 444...
• December 30, 2011

"I finished a full 10 days of that medicine, the doctor did not tell me anything about probiotics, so right after taking Pylera, I had some issues with my bowel movements, had constipation for a while, did a colonoscopy and still cannot figure out what is wrong with me. Having constant pain under my left rib, doing more tests, going from family doctor to gastroenterologist. I would recommend, before taking Pylera medication, to do deep research on side effects because with bad bacteria, your colon's good bacteria gets killed as well as the bad ones."

• Rit...
• June 22, 2014

"Horrible experience! First half of treatment was manageable but not pleasant. Day 8 was by far the hardest, with extreme nausea, dizziness, heart flutters, bloat, and the usual diarrhea. For day 9, I battled with the thought of taking the pills for an hour. I felt like I was playing Russian roulette. Sitting here waiting for the agony. Day 10 can't get here soon enough! However, I'm thinking anyone who has undergone chemotherapy must think I'm such a wimp!"

• Km2...
• Taken for less than 1 month
• May 20, 2017

"I just wanted to share some positivity on this site. Most of the reviews are scary and disheartening. I will say Pylera is rough. It made me feel worse for a few days, especially around days 5-10. I never was nauseous, really, no vomiting, but I was completely beat. It's a rough medication. Get tons of sleep, rest as much as possible, and drink TONS of water. Eat enough with the doses, too. I haven't had any symptoms at all in 3 days, which is the first time in a year that I can say that!!!! Fingers crossed it sticks. Also, AVOID EMOTIONAL STRESS. Plays a HUGE factor in your well-being and recovery."

• Anonymous
• April 20, 2010

"I don't really know how to rate a medicine; I just share my experience. My doctor warned me that this antibiotic is very harsh and I might feel bad during the course. However, I am taking it for 8 days, and the only side effect I encountered is a bitter taste in my mouth, but it's not a problem. I just drink a lot and chew gum when it gets really bitter. I am of a slim and petite complexion (100 lb only), so I expected to have bad side effects, but I feel quite normal. Also, I am eating well before taking medicines (more veggies), drink lots of water, take strong probiotics (50 billion), and drink organic kefir with live culture before going to bed and taking the bedtime portion of Pylera."

• H...
• Taken for less than 1 month
• February 10, 2016

"I'm on day 9. Number one side effect for me has been the inability to focus on one thought for more than a few seconds, which has affected my work. It really is a brain fogger! On day 5, the metallic taste/sour mouth was pretty awful all day, but it abated gradually over the last few days. If I don't drink a lot of water (20 oz or more) with each dose, my urine is very dark, which is scary, but drinking more water does help. I agree with the comments that you should eat a full meal with each dose, even at bedtime. It is rough doing the schedule and getting in the food, water, and pills four times a day. On a few days, I had to set an alarm and get back up at midnight or 1 am to take the last dose. Stick with it, power through the 10 days."

• Tho...
• Taken for less than 1 month
• June 8, 2016

"I was prescribed Pylera after a triple therapy failed. I'm now on my last day of it. The gastritis pain is slowly going away, but still there (you will have to wait the next 4 weeks for it to heal). The first 5 days I didn't feel anything different, then on day 5, I had a terrible headache, anxiety, and nausea. Day 6 and onward, my body adapted, and it became less powerful, but still pretty crappy. I'm not gonna lie to you, you basically feel hungover for the last 4 days. Drink a lot, force yourself to eat, and go out (the computer will make the headache horrible). Stay strong, brothers, it's a pain, but this has a 90% success rate."

• Sue...
• March 8, 2021

"I’m on my 2nd day, and I feel like quitting. My whole body is aching, and I have sleepless nights. My stomach is inflamed and bloated. I'm having headaches. I noticed some blood in my urine and blood in my stool. I don’t have access to my gastrologist because he's fully booked. I can only see him in a month's time. I have to see a GP to explain to him the side effects because I feel like it’s not working on me. I’ve used metronidazole before, and it doesn’t really work on me. I hope my body is not resistant to it. I’m just praying for strength because I’m not sure if I can pull through. I wish I had read these reviews before starting the meds."

• Rox...
• May 7, 2015

"I tried Prevpac first, but I had an allergic reaction and had to stop taking it halfway through the course. It seems to have cured me for a few years, but more recently I had a GI H. pylori recurrence. I am taking Pylera and am on day 9. I have had very little side effects. In fact, I am feeling much better, and my bowel movements are better as well. I did feel nausea and weakness on one day, but I had barely eaten anything because of lack of appetite. Advice: eat 4 healthy meals a day before I take the medication. Yogurt and probiotics in the morning and fruit. Absolutely no coffee or acidic anything (vinaigrettes, ketchup, tomato sauce), no soda, and anything sugary. No red meat and nothing too heavy or fatty. Hope this helps."

• Fad...
• Taken for less than 1 month
• September 6, 2018

"Right now I'm on my 7th day of taking this horrible drug. I have never felt so awful as I do with the side effects that I got from Pylera. I had a fever. I had pain in my neck, hands, legs, butt, head, back, liver, and I vomited. Today, I woke up feeling as if I was in Antarctica. I also felt very dizzy along with some nausea. I couldn't get out of bed because my legs were refusing to stand. I'm also seeing very blurry visions. I don't feel like my normal self since I'm always active. I kept crying all the time from pain. I hope I never get to have this medicine again. By the way, this is my second time taking Pylera since I took it in 2016. Please pray for me."

• ano...
• May 23, 2012

"My experience with this medication has been awful. I'm on my 10th day, but I have missed 5 doses. This medication made me so sick I had to go to the emergency room. Severe headache, nausea, bloating, black stool, and urine. You are supposed to eat with it, but I couldn't because of the bloating. Which in turn made me sick because I wasn't eating. I have completely stopped taking the medication in the hopes that the H. Pylori is gone."

• Pau...
• Taken for less than 1 month
• December 19, 2018

"I am on day 6 of the treatment, and I have never felt so awful in my entire life. I am very nauseous all the time, my mouth is dry, I have no appetite, but I force myself to eat to combat this feeling. Urine is a very dark amber color, warm sensation in my knees (like standing in front of a heater), tired all the time, could barely get out of bed after sleeping over 10 hours. I am ready to quit. I feel like H. pylori is better than having to deal with the side effects. I am dizzy, can't focus, and when I walk, I feel very wobbly - it was very hard to drive to work, but I have no other option."

• Anonymous
• October 26, 2009

"I've been taking Pylera for the last 5 days, and I'm feeling really bad. The most horrible effect is that metallic taste I have in my mouth 24 hours a day. I just can't stand it anymore, and I have 5 days of treatment remaining."

• stu...
• Taken for less than 1 month
• May 25, 2014

"It's three days after finishing the tenth day of taking Pylera. The first four days of taking the medication, I felt no side effects. On days five through ten, I was nauseous, dizzy, and had a headache, especially right after taking my daily doses. I took the medicine with a meal three times a day and with a light snack before bed. Stools also turned a dark greenish color and were often irregular throughout the day, bordering on diarrhea. I also had a feeling of uneasiness, like a panic attack, right after taking the medicine on three occasions. I'll have to check with my doctor to confirm if the H. pylori has been eradicated and also wait a few weeks to see if my ulcers heal (which I've read can take from a few weeks to a few months)."

• GAA...
• Taken for less than 1 month
• September 9, 2022

"H. pylori. (13.00) Pylera 4x3 + omeprazole 2x1 for 10 days. All doses were taken at the same time 6-7 am/12 pm/6 pm/12 am. Days 1-3 were insane. The nausea - exorcism-like!! I cut all the dairy, multivitamins, products high in calcium and iron. No alcohol. No cigarettes or vaping, which as a smoker I had no cravings at all. Pills after meals and with a little bit of food, it helped to ease the nausea slightly. Was afraid it could affect the treatment. I made sure I was not laying down for 10 mins post-pills. Currently day 9, most symptoms became better after day 5. However, then I felt very exhausted mentally and physically and nearly cried every time taking pills, even when symptoms were not as bad as at the beginning. Over the 9 days, I had many changing side effects: nausea, muscle contractions, dark stools, back and chest rash, sweating, lightheadedness, fever, loss of appetite, sadness, sensitivity to noises and light, fatigue, sour taste, and bloating that never went away :/"

• dyr...
• December 17, 2009

"I went for a colonoscopy, and the doctor told me I needed an endoscopy as well. In two weeks, I got a phone call that I have an H. pylori infection in my stomach and was prescribed Pylera. I was taking 12 tablets a day and 1 tablet of Protonix for 10 days, and now I feel much worse than before. Before I was healthy, and now I am sick to my stomach."

• Tat...
• Taken for less than 1 month
• September 13, 2019

"The med Pylera is very strong! It’s been a nightmare. Today is my 6th day, and I can’t wait to be done with it. The first 4 days were the worst since I had side effects like nausea, depression, dizziness, it was bad. I wanted to cry. I didn’t know you are not supposed to eat dairy products with it, so I ate yogurt and took my pill, and it was a nightmare that night and the following day. Then I was told I have to stop the dairy and eat a good meal and lots of water while taking it. I’m on my 6th day, I’m doing better, and I do feel better. Praying that this will work and I will feel better. Only 4 more days to go. Good luck, guys! Remember, no dairy, big meal before pills, and lots of water."

• Man...
• Taken for less than 1 month
• February 28, 2019

"I was terrified to take this medication after reading about other users' experience. I did experience some of the common side effects, such as headache, fatigue (especially on day 8), some diarrhea, a bitter taste in my mouth, etc., but it was not as bad as described by others. It is critical to eat a full meal prior to taking it and a good snack at bedtime (one time I took it on an empty stomach at night and had bad diarrhea the next morning). Directions call for taking it with 8 oz of water, but I drank more. Having large scheduled meals and drinking a lot of water was challenging, but it seems to help with side effects. Staying away from dairy, red meat, and spicy foods was difficult. My doctor recommended taking probiotic Align for 1 month after finishing the course to restore good bacteria."

• Kel...
• September 17, 2015

"Day six. Watery stools. Loss of appetite. Shaky. Brain fritz. Sunburn. (own fault, should have known better) Food tastes odd. Tired and have nausea. Hope this works. My insides sound like two cats fighting in a burlap bag."

• Anonymous
• Taken for less than 1 month
• May 5, 2018

"I can honestly say I was scared to start my regimen of Pylera and omeprazole since I’m very sensitive to medication. The only side effects I had were dark stool, metallic taste, and dizziness. I started out every morning taking ginger capsules for the dizziness and probiotics for my gut. I also ate before each dose of Pylera and drank plenty of water. It was a little intimidating to see the box of antibiotics before I started, but I did it!"

• Tan...
• Taken for less than 1 month
• August 16, 2018

"I'm just finishing my 10-day protocol, and I am hoping that I never, ever have to take this poison again. Yes... I felt like I was being poisoned with some toxic combo pill pack. It was horrible. I just knew the 'ends justified the means,' so I pushed through. The side effects I experienced were extreme fatigue, headaches/migraines, dark stools, phlegm, blurry vision, body aches, heart palpitations with cough (which I had to go to the ER for because I almost passed out), neck pain, weird taste in mouth, loss of appetite, nausea, and stomach cramping. It's a good thing I don't work, or else I probably would've been fired. I was literally in bed almost the entire time. So, no... uh-uh... not taking this stuff again."

• Jol...
• Taken for less than 1 month
• January 15, 2013

"I have been taking this medicine for about 4 days now. I constantly have a dry mouth and it makes me feel ill the majority of the day. Do eat a full meal when taking it, it makes the feeling not as bad. I feel best on the last dose because I know I'm going to bed. Hopefully, I will feel better as time goes on. I don't really mind taking the 14 pills a day, I just want it to go by quickly."

• Ste...
• Taken for less than 1 month
• March 12, 2019

"Tip for taking Pylera: Make sure you eat a good amount of food before taking this medication. Also, take it with a lot of water, at least 8 oz. I did this, and my nausea was not nearly as bad as when I didn’t. It did make me poop a lot, and it was black, so just be aware that it’s normal with this medication. I did get tired about 5 days into it, but it was nothing I couldn’t handle for a few days. I’m sure everyone is different, but hopefully, this helps."