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Xofluza and Headaches: What Users Say

Headaches: mentioned by 6 users (21.4%)

Based on user experiences from 28 Xofluza reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 21.4%
body aches 14.3%
chills 10.7%
tiredness 10.7%

Reviews for Xofluza

Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • January 11, 2020

For Influenza "Started showing symptoms of the flu around 4 a.m. yesterday morning, cold sweats and pounding headache. Temperature was 101.6. By 6 a.m., symptoms worsened with severe body aches, chills, and headache. Went to urgent care around 10 a.m., and the doctor gave me a free sample of Xofluza. Took the medication with food around 11 a.m. Still dealt with some gnarly symptoms all day yesterday with my temperature going up to 102.8. Napped on and off with cold sweats, headache, body aches. I also took ibuprofen every time my temperature had risen and headache worsened. By 11 a.m. today, my temperature was finally 97.9. My headache isn’t as severe, but it’s still there. My body aches are gone. By tomorrow, I should be good as new. I highly suggest this medication."

9 / 10
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15 Report
  • Anonymous
  • Taken for less than 1 month
  • January 11, 2020

For Influenza "Started showing symptoms of the flu around 4 a.m. yesterday morning, cold sweats and pounding headache. Temperature was 101.6. By 6 a.m., symptoms worsened with severe body aches, chills, and headache. Went to urgent care around 10 a.m., and the doctor gave me a free sample of Xofluza. Took the medication with food around 11 a.m. Still dealt with some gnarly symptoms all day yesterday with my temperature going up to 102.8. Napped on and off with cold sweats, headache, body aches. I also took ibuprofen every time my temperature had risen and headache worsened. By 11 a.m. today, my temperature was finally 97.9. My headache isn’t as severe, but it’s still there. My body aches are gone. By tomorrow, I should be good as new. I highly suggest this medication."

9 / 10
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15 Report
  • Mik...
  • Taken for less than 1 month
  • December 19, 2019

For Influenza "Son had the flu, I was his primary caregiver, and despite my best precautions, I started to feel bad at 9 AM this morning. Temp was 100 by 12 PM, and my body started to ache. Decided to head straight to the urgent care, and they prescribed me Xofluza. Took my first and only dose at 2 PM, my temp was 102.8, and my muscles were aching as if I pulled my back. Nose was stuffy and had a bad headache. It is now 8:30 PM. My temp is 100.3, and my body aches are dramatically reduced, headache gone, and nose is no longer stuffy. I feel way better and have a feeling with a good night's rest I will be all better. My only advice is to start this ASAP, like I did."

10 / 10
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8 Report

Frequently asked questions

  • Lad...
  • Taken for less than 1 month
  • March 8, 2020

For Influenza "I felt bad on Tuesday, as if I had a bad sinus infection, got a doctor's appointment on Wednesday. Tested positive for flu type A. Took Xofluza that Wednesday. On Thursday, woke with my head pounding, ears stopped up, runny nose, deep cough, and a sore throat. Friday, had a horrible, painful day, definitely the most achy, pain-filled, weak day of them all. Saturday, feeling a little better but still a horrific cough, sore throat, headache, and weakness. Sunday, thinking I may have to return to the doctor Monday. I still have weakness, runny nose, ears full, deep cough, sore throat, barely a voice, and basically the same way that I felt when I went to the doctor. I don't think this medicine works well with me."

1 / 10
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  • J K...
  • Taken for less than 1 month
  • January 19, 2025

For Influenza "Started with a terrible cough, chills, sweats, headache Thursday PM. Friday terrible, Friday night even worse. Traveling, so got tested Saturday AM Influenza Type A. Started Xofluza at 2:00, thus at the 48-hour window. Body temperature regulation and cough appeared to be waning at 10:00 PM. Had to stay up to watch NFL playoffs. Good night sleep, no chills or sweats. Typing this at 6:50 AM Sunday. Same time yesterday in a coma. This is the second time I’ve had this miraculous turnaround. Studies suggest it works equal to Tamiflu but with one dose. I don’t believe that. Tamiflu never produced such a quick response for me."

10 / 10
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  • Nan...
  • Taken for less than 1 month
  • November 4, 2022

For Influenza "I went to the doctor for an earache, but had been feeling really rundown from working 7 days a week. Tested positive for both flu A and flu B. Immediately got my prescriptions filled and took the single dose of Xofluza. My body aches have been minimal (nothing like the debilitating aches usually experienced with the flu), but I still have a horrible headache and fatigue. Today was day 3 after diagnosis and has been the worst day of symptoms, but Xofluza has made a huge difference in the severity. I haven’t experienced any side effects that I know of. Even though Xofluza cost $98 with insurance and a discount card, I’d definitely take it again."

9 / 10
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