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Z-Pak and Headaches: What Users Say

Headaches: mentioned by 3 users (8.8%)

Based on user experiences from 34 Z-Pak reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 32.4%
upset stomach 23.5%
anxiety 8.8%
cough 8.8%
dizziness 8.8%
headaches 8.8%
nausea 8.8%
stomach pain 8.8%

Reviews for Z-Pak

Commonly mentioned side effects
  • Chr...
  • Taken for less than 1 month
  • May 18, 2023

"I was prescribed a Z-Pak before a trip out of the country for potential strep throat. A family member had strep, and I was feeling off prior to the trip, so I called a teledoctor, and they prescribed the Z-Pak. I took the first dose. Within 45 minutes, I had diarrhea, and my heart rate shot over 120 bpm. I attributed these symptoms to anxiety prior to the trip. Went to bed and woke up around 2:30 am sweating, my heart racing, and my body shaking/jerking. Needless to say, the trip was canceled. Anxiety, headaches, and diarrhea lasted days after, along with sleeping hours upon end. Literally felt like I was hit by a truck. I will not be taking a Z-Pak again."

1 / 10
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6 Report
  • Nev...
  • July 20, 2017

For Bacterial Infection "Took first dose of two tablets for bronchitis and lost all ability to taste food in a few hours, also had to leave work as I felt very tired. No change to bronchitis symptoms. Day two, continues to have no ability to taste food and headache (5/10) began after the second dose. Bronchitis symptoms mildly improving. Following the third dose, severe headache and earache, took tramadol, which made it manageable. Not taking the fourth dose, currently experiencing horrific stomach cramps and diarrhea. Still can't taste anything and have a significant headache. Felt much better with bronchitis symptoms, feel like death. Never again."

2 / 10
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7 Report
  • Hel...
  • Taken for less than 1 month
  • December 16, 2021

For Bacterial Infection "It helped my sinus infection after day two, but the side effects are worse than how I was originally feeling. My legs are burning on fire, heart racing like crazy, high blood pressure, headache, body aches, fighting back and forth with the same fever I already had, but it’s worse, swollen lips and lymph nodes."

3 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.