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Amantadine for Chronic Fatigue Syndrome User Reviews

Brand names: Gocovri, Osmolex ER

Rating: 9.2

Amantadine has an average rating of 9.2 out of 10 from a total of 6 reviews for the off-label treatment of chronic fatigue syndrome. 100% of reviewers reported a positive experience, while 0% reported a negative experience.

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  • Anonymous
  • November 17, 2010

"I have been on amantadine intermittently for years to deal with the 'viral' component of my Chronic Fatigue Syndrome. I took 200 mg daily for over 3 years. It helped me when nothing else would. I now take it when I feel a viral episode coming on. Without the drug, the viral symptoms (nausea, sick feeling in head, and extremities) are much worse. Oftentimes I have difficulty taking drugs, but Amantadine (to my knowledge) has not presented with any prominent side effects. It does seem that when on it for extended periods of time, the body gets used to it and it becomes less effective. For that reason, I take it during periods when I need it the most. I am very thankful for this medicine!"

8 / 10
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  • the...
  • Taken for 1 to 6 months
  • July 16, 2020

"The only med that worked for me was Wellbutrin. But with the anxiety and panic it induced, I just couldn't keep going on with it. Amantadine was prescribed off-label for the same issue, it worked like magic! I had forgotten what a normal person's day felt like. This drug really has given me my life back. None of the side effects that made me quit Wellbutrin."

10 / 10
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52 Report
  • Til...
  • Taken for 2 to 5 years
  • May 2, 2016

"I had CFS for 7 years, and when I had an episode of the illness, I would be bedridden for six to nine months. The doctor gave me amantadine in the hospital, and I instantly felt much better. Now I take it when the disease starts, I take from one to three daily for about a week. It helps me function normally, and it always gets me out of bed. When I was taking it for a longer period, it would start to cause symptoms similar to the disease, so the best way for me is to take it from time to time when I feel I have a relapse."

10 / 10
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70 Report

Frequently asked questions

  • Bea...
  • Taken for 2 to 5 years
  • June 15, 2018

"I was prescribed amantadine in 1990 for postpartum depression. I took it for 5 years faithfully, and it helped me a lot. I had lost two brothers to muscular dystrophy, so I was down for the count. My doctor put in his file as chronic fatigue syndrome for insurance purposes because they didn't cover the cost of depression medication much back then. Just shows you how the mental health system is broken. Even in the 90s, it was a great med....."

9 / 10
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49 Report
  • gar...
  • Taken for 6 months to 1 year
  • December 22, 2016

"Chronic fatigue since I was 3 years old. I'm now 55 years old, started taking amantadine. Found it hard to tolerate. Went down to one 100 mg every two weeks. Went back up until I was at one every day for 5 days. Going strong!"

10 / 10
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49 Report
  • gar...
  • Taken for less than 1 month
  • March 12, 2016

"I've had chronic fatigue since I was three, that was the result of a basal ganglia stroke, and that has not been intermediate. I've been taking the drug for about a month, and it's been like a dam against the fatigue. I struggle against hypertension because muscle tension does not go the distance, and this has not become any easier yet. Over the last week or so, the 'hard to tolerate thing' has kicked in with the drug. So, I stopped taking the drug today and immediately feel better, but the positive effect lingers. I expect I will be taking the drug intermittently, which I expect is the key. After all, there may be a very small chance of a basal ganglia stroke."

8 / 10
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35 Report

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