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Alprazolam for Depression User Reviews

Brand names: Xanax, Xanax XR, Alprazolam Intensol

Rating: 8.5

Alprazolam has an average rating of 8.5 out of 10 from a total of 102 reviews for the off-label treatment of depression. 79% of reviewers reported a positive experience, while 9% reported a negative experience.

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Reviews for Alprazolam

Commonly mentioned side effects
  • Hew...
  • Taken for 10 years or more
  • May 9, 2016

"I suffer from social anxiety, rarely leave the house. The anxiety leaves me isolated, which causes extreme depression. With Xanax 1mg to 2mg, it takes all anxiety away and calms my depression. 10 out of 10. Taking Xanax for over 20 years now."

10 / 10
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241 Report
  • amv...
  • November 20, 2014

"This is the best medicine out there. It makes me a better person. I love it. I have anxiety and depression, and this is the only thing that makes me tolerable to be around. Levels me out and makes me happy."

10 / 10
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267 Report
  • Sev...
  • Taken for 10 years or more
  • October 11, 2016

"I know what it's like to lose 30 pounds in one month from depression. No appetite, can't walk without getting tired, laying in bed all day crying, and nightmares night after night. It's so annoying when psychiatrists won't prescribe this because of fear of addiction. Well, guess what? If I hadn't found Xanax, I would have committed suicide a long time ago. You can take this medicine long term if you have severe depression and are responsible."

10 / 10
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206 Report

Frequently asked questions

  • Its...
  • September 10, 2015

"I've been on and off Xanax for 22 years. It's the only drug that makes me feel normal after a lifetime of anxiety and depression. It's awful that people use it recreationally, and that's made it difficult to get a prescription for it because of others' abuse of it. It makes me feel normal. So obviously, I need it. I have nothing but good things to say about this drug. It helps me not want to freak out and shake due to anxiety. If you really need to be on it, it's amazing."

10 / 10
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202 Report
  • ms ...
  • November 3, 2013

"The first time I took Xanax was when I was having dental work, and it was prescribed for the acute anxiety I feel with dentists. This past year, my regular doctor suggested I might like to take it from time to time because of depression and anxiety. It helps tremendously. I usually break the 0.25 mg pill in half and just take half of one. I do not use it every day, but when I need it, it's wonderful and gets me to the next day."

10 / 10
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221 Report

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  • Anonymous
  • December 14, 2011

"I'm 37 years old. I have been dealing with severe depression all my life. I have tried every antidepressant medicine under the sun, some were mildly effective, but the side effects were worse than the depression. I went to a new doctor, and he asked if I have ever tried Xanax. I said no, I thought that was used for anxiety. He prescribed me 1.5 mg a day. I started noticing a difference the first day. This stuff is amazing, I've been on it for two months, finally some relief. It's unfortunate it's abused so much and so hard to get a doctor to prescribe it. I haven't had any side effects, I have such a positive outlook on everything now. It has completely changed my life for the better. All the symptoms that came along with depression are gone."

10 / 10
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210 Report
  • lil...
  • Taken for 6 months to 1 year
  • July 8, 2013

"I have had severe panic attacks for years. Finally got a doc that prescribed this, and wow, it is an amazing medicine. My doctor retired, and it seems every doctor now is afraid to prescribe it due to the ones who abuse it. I don't take it daily, but my mind stops racing, and I can sleep when I use it. I gave it a 9 because of slight drowsiness some mornings."

9 / 10
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183 Report

More FAQ

  • Big...
  • Taken for 2 to 5 years
  • January 2, 2015

"I've suffered from generalized anxiety for 25 years. At one point, I could barely leave my house. Afraid to drive on bridges, tunnels, fly... I even had anxiety about taking anxiety medication. Xanax was a game-changer for me! I rarely take it, but I've taken trips I never thought I would be able to take. Get this, I was even able to skydive! Not bad for an agoraphobic. It builds confidence. Just having it in my pocket really helps. I had to take a 0.5 mg dose tonight because I've been in panic mode for five days and I finally needed to reset my mental state. I think David Burns' 'Feeling Good Handbook' is an awesome tool too. I'm rambling because after 5 days of super anxiety, I finally took a 0.5 and now I feel great."

10 / 10
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155 Report
  • Ben...
  • February 19, 2017

"From 2002-2017 I have been on many different types of medications: Klonopin, Valium, and Xanax, not to mention all the psych drugs, none that helped until my doctor realized I had social anxiety and paralyzing panic attacks. By far, the best for not only my depression but my anxiety as well was Xanax 2mg. I had to take at least the full bar to ease my anxiety, however, not only did it help with my fears and anxiety, but it also helped with my depression which stemmed from my constant panic attacks. It is easily abused, however, when it's needed, it's a savior and can help me get what I need to accomplish done as a mother, a wife, a personal trainer/lifeguard, and a graduate of Homeland Security and Emergency Management, which without Xanax, I wouldn't have."

9 / 10
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123 Report
  • Anonymous
  • February 29, 2008

"I have extreme depression and Anxiety - sometimes panic attacks. I have this horrible habit of pulling out my hair - on my head, eyelashes, and other areas excessively. Xanax and Lexapro have made me feel normal - for the first time in years, I actually have eyelashes growing in. I don't care what people say about the negative effects of Xanax - I personally know I needed it. I feel like the nightmare of my mind has been treated."

10 / 10
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220 Report
  • DEW...
  • Taken for 2 to 5 years
  • October 15, 2015

"Began taking Xanax during a time when my one and only child left home for college and I lost my job a month later. It allowed me to cope and move forward. The most I ever took was 1 mg per day, but I now take 0.25 when I have periodic depression and anxiety. I sometimes go 6 weeks without taking one. The best way to describe it is like rebooting your mind. Life saver for me."

10 / 10
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126 Report
  • twe...
  • March 27, 2011

"I have been taking 1mg Xanax 4 times daily for 25 years. It is the greatest medicine for depression ever! No, it does not make me drugged-sluggish or anything bad. Xanax lifts me up when I get down, and I do not even want to think about never having Xanax. I know of several friends and family members it would change their life for the better if their doctors would only prescribe it to them. Of course, they should not start on the dosage I take but at least get them started and take it from there. The antidepressants just don't do it for me. I have tried several over the years, and they just make things worse for me. Xanax allows me to be happy and tolerate the tough times."

10 / 10
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166 Report
  • Nor...
  • October 20, 2011

"I've had big problems with both depression and anxiety, and I've tried most of the benzodiazepines that are available (Diazepam, Clonazepam, Flunitrazepam, Nitrazepam, Oxazepam, and so on), and also a couple of different antidepressants. SSRI's and Mirtazapine (brand name 'Remeron'). And after trying all of these different medications, I didn't think I EVER could get rid of the depression and anxiety and live a normal life (which in turn made me even more depressed), but then in comes Xanax! And it didn't take long before I was almost entirely free from both the depression and the anxiety, which had such a strong grip on my life for such a long time and almost ruined my life! I really feel like I owe my life to the wonderful Alprazolam!"

10 / 10
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155 Report
  • sun...
  • March 28, 2013

"I have been taking 0.5 mg, 1 at night for 8 years. I get 30 for a month's supply. It has been a miracle for me and my depression. I have tried all antidepressants which only make me feel worse and even suicidal. Xanax is a lifesaver for me. My doctor now wants me to start again with an antidepressant. I will not. I think he wants to wean me off Xanax because of all the negative addictive effects."

10 / 10
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159 Report
  • Sta...
  • November 14, 2012

"This is the only one I feel safe taking. I'm prescribed 0.25mg 2x a day or as needed. I took Zoloft, Wellbutrin, Seroquel, etc. Felt horrible coming off all of these. With Xanax, I feel like I can take it when I need it and put it down the next day if I don't. Unlike the other antidepressants that cause brain zaps or worse side effects, feelings of a rollercoaster coming down."

10 / 10
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139 Report
  • Gr8...
  • March 10, 2016

"I agree with everything that has already been said here. I am just so incredibly grateful that I was able to build a trusting relationship with my doctor so that he feels comfortable prescribing it. Xanax really is the only thing that helps me untangle myself when the anxiety takes over. What I love the most is that I can count on it to do the job and not leave me feeling strange later. It just smooths out the wrinkles and kinks that I get into every so often. Just knowing that I have it in my cabinet to lean on is in itself a big help for me - my secret tool. Yes, it's a shame something so helpful to us is abused, but that is with everything in life. Be happy we aren't Guinea pigs anymore with the crappy meds :-)"

10 / 10
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103 Report
  • cuc...
  • Taken for 10 years or more
  • January 2, 2015

"I have dealt with depression, anxiety, social phobia, or social anxiety, whichever label they want to use for it these days. I have dealt with these issues pretty much since kindergarten. Well, mainly the extreme social phobia/anxiety at that time, which they used to just call 'shy'. When I was 18 and was seeing a psychologist, he diagnosed me as having agoraphobia. I'm guessing because they really didn't have the term 'social phobia/anxiety' at that time. I finally started taking Paxil, and it worked well for 10 years. Then, I maxed out on dosage, and it stopped working. I tried all the other SSRIs/SSNRIs. Effexor XR worked best but didn't help anxiety or social phobia issues. I got on Klonopin, then Xanax eventually. Benzodiazepines are life savers for social phobia."

10 / 10
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119 Report
  • Rex...
  • Taken for 5 to 10 years
  • September 16, 2016

"I had always heard the negative jargon of Xanax, and was afraid to take it because I was afraid I would be addicted and unable to control it. Eventually things were too tough and I was in one of the darkest points of my life. So I broke down and talked with my doctor about giving it a try. It totally changed my life. It helped me to focus more at work. It helped manage my anxiety so my mind could rest and I could sleep. I could see how this medication could be misused. It's important to take as prescribed."

10 / 10
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88 Report
  • Bus...
  • March 15, 2016

"If I could rate Xanax higher I would, this is without a doubt the most effective medication I've ever taken for anxiety, and fast-acting. I've always dealt with public speaking anxiety since high school. I'm 29, healthy, and active, and have never been depressed, so that's why I've been reluctant about SSRIs. My GP prescribed Celexa, went up to 20mg and it was a nightmare, had panic attacks and very vivid intrusive thoughts. My GP switched to Lexapro @10mg and I still get panic attacks. If I get a panic attack, I take a 0.50mg of Xanax and it takes like 15 min to kick in and I feel great - I hate SSRIs and wish Xanax was a daily med."

10 / 10
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97 Report
  • Alp...
  • November 30, 2012

"I am prescribed 45 2mg tablets a month (brand name). I take a half 3 times a day, and am also prescribed 90 1mg Klonopin a month - morning, afternoon, and night. While the Klonopin seems to aid in keeping the panic/anxiety at bay and keeping me calm and relaxed, the Xanax is the real 1-2 punch to panic attacks and anxiety; it takes all my sadness and depression away and allows me to think about all the amazing things I am working on not as a chore or as work, but as a creative idea. Being prescribed 2 Benzos is 'odd' practice like Klonopin 3 times a day with a fast-acting Xanax."

10 / 10
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126 Report
  • Anonymous
  • May 3, 2012

"I have been diagnosed with depression and panic disorder (for 20 years now). I learned over the years that if I could keep my anxiety/panic under good control, I would be much less likely to go into depression (uncontrolled anxiety greatly increases the chance I will experience depression). Xanax works extremely well at keeping my anxiety (and hence depression) under control. These days I don't need to use it continuously because just knowing that Xanax is there and works so well if I need it has a calming effect. I didn't give Xanax 10/10 though because it has one annoying side effect for me: it kills my libido rather effectively if I take it for a few days. Apart from that, very tolerable - way more so than any antidepressant I was on."

8 / 10
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118 Report
  • Way...
  • Taken for less than 1 month
  • October 7, 2014

"I was prescribed Xanax because my half brother died, and I could not cope with it alone on just taking Pristiq for depression. Taking both of these medicines has really reduced my depression tremendously to where it only affects me a little now and not so many days in a row. I'd really like to stay on Xanax with my other antidepressant medication Pristiq 100mg because it's helping a lot!"

10 / 10
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100 Report
  • Anonymous
  • June 14, 2011

"Xanax is one of the best medicines ever made to help depression and anxiety. They shouldn't be so hard to get prescribed though. They are a wonderful medicine that makes you happy even when you have major problems. If everyone took Xanax, it would be the happiest country in the world."

10 / 10
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122 Report
  • Anonymous
  • March 26, 2010

"I think Xanax works great taking it along with an antidepressant. Right now I am currently taking 2 mg of Xanax along with 20 mg of Celexa. I believe it has helped me out in so many ways. I used to have anxiety and panic attacks pretty much all day, or part of the day that I was awake. I haven't felt this good about myself in a long time. Sometimes I would get a panic attack just from walking in a public place, such as a supermarket, and then came the heavy breathing and the nervous feeling out of nowhere. But the Xanax put all the feelings to rest. I know it's a narcotic and it can be abused and it also can cause dependency. But if used the right way, I know it can work for some of the worst conditions of depression."

10 / 10
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118 Report
  • Ann...
  • Taken for 1 to 6 months
  • June 20, 2017

"I've started to take Xanax 3 months ago, 0.25 then 0.5mg a day. Experienced a rapid heartbeat at first, but chose to give it a chance anyway and after 2 weeks it was back to normal. Now I take Xanax 0.5 and Bupropion 300mg a day for my depression and anxiety. I can tell it really has changed my life so far, I can feel joy or calmness again (before I couldn't at all). I hope to get back to normal soon. Can't even describe how I'm glad I've started to take these medications. Although I know many people have severe side effects, the thing is - it's very individual, you have to try and find a medicine that works best for you. Many people take Prozac, but I almost died when I took it - side effects were terrible, I even experienced hallucinations."

10 / 10
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67 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.