Praluent for High Cholesterol User Reviews (Page 3)

• Mike...
• Taken for 1 to 2 years
• February 28, 2020

"I'm a 73 year old man. I had a heart attack 3 years ago at which time my LDL was 250mg. My cardio doctor put me on 40 milligrams of Atorvastatin (Lipitor) daily which lowered my LDL down to 125mg which was not low enough. He started me on Praluent 75mg painless injections in my upper legs once every two weeks that lowered my LDL to a very low 25 mg. after taking it for only two months with no side effects. I hope the price doesn't skyrocket so I can continue taking it til I die someday. I never thought I would get my LDL down to 25. It's unbeleivable. I hope it keeps me from having another painful heart attack. I'm told that Repatha and Praluent are about the same medicine."

• PEano
• Taken for 1 to 6 months
• May 1, 2020

"I started taking Praluent in January 2020. A few weeks in I had an awful UTI. Never ever had one before. It was miserable. Then six weeks later had another UTI. Only thing new was the Praluent. I started looking into the side effects and see that was a highlighted side effect. As I read more on this drug I see it may be causing the fatigue and pain in my lower back and pelvic area. I told my doctor I wasn’t going to continue. This was a last option as I have severe side effects from everything else we have tried. I did have blood work the other day and my numbers were lower but triglycerides were still high."

• Love
• Taken for less than 1 month
• March 24, 2018

"I am a 64yr old female. I did my first shot yesterday. Had to go to ER with very high bp, rapid hear bears, swollen eye lids, jittery, head and neck pain, itching, red skin. It was a negative experience"

• Chris...
• Taken for 2 to 5 years
• May 24, 2024

"It has adjusted all my cholesterol levels into normal ranges when they used to all be outside of those ranges. Even when I was 25 years old and playing soccer, I had high cholesterol. I did not tolerate statins, as indicated by a *very* high 'Creatine Kinase, Total, Serum' blood test. Then, I had a heart attack and started taking Praluent. Now I am doing fine and all my cholesterol values are in normal ranges, plus, my cardiologist's stress tests are all normal. Obviously, it's working great for me. I only have minor side effects such as shivering for 1 to 2 minutes about once a month or so when sleeping."

• Diane
• Taken for 1 to 2 years
• April 11, 2024

"I’ve been on Praluent for over 2 years and have not had any side effects. I take the injection every 2 weeks, and all cholesterol levels are very good. If I had read all of these negative comments before using this medicine, I would’ve been petrified to try it."

• JJ2905
• Taken for 1 to 6 months
• April 8, 2018

"I have been on this drug for 3 mo. Everytime I inject---for 36 hours I get leg pain and hand cramps and feel very tired. I am unable to sleep due to the leg pain and both hands have severe spasms. Joints seem to be getting worse with movement in tennis and pickle ball . I am going to see my doctor and stop this medication. Will have to do diet alone because all statins cause body spasms and cramps"

• Nagi
• Taken for 6 months to 1 year
• October 16, 2016

"Praluent was working great for the past 9 months without any side effects but during the last 3 weeks I started to have the symptoms of arthritis that is some pain in the joints. It improves some when I walk. I hope these symptoms will not further increase. Will update you in another 2-3 weeks."

• uniqu...
• Taken for less than 1 month
• April 29, 2020

"Mine is the usual story. I got horrific muscle cramps, especially in my thighs, from taking even the smallest imaginable dose of a statin (5 mg per week). I just had to stop taking any statin. I tried diet alone to lower my numbers and that didn't work. I fought trying an injectable for my cholesterol/cardiovascular issues for several years until I didn't have any options left. Two weeks ago I gave myself my first Praluent injection. I'm needle phobic so imagine my surprise when I never even felt the tiny needle and had to check to make sure it was actually in my skin. Then yesterday I did my second of my two monthly injections and it was the same; over in about 5-10 seconds! This was the big hurdle for me, so if you think you can't do an injectable, try it. It's really no big deal. This drug costs me $250/month with my Blue Cross insurance. I am hoping as users go up, the price will go down. Time will tell if my cholesterol goes down."

• Anonymous
• Taken for 5 to 10 years
• January 31, 2024

"Fifteen years ago I had two stents as I was suffering from blocked arteries and terrible angina. I was only 43 years old. I took statins for years, as much as my body could stand, as I suffered from insane muscle pain to the point where I could hardly walk. Because of this, my statin use dwindled to once or twice a week. Five years ago, with my cholesterol high again, I had a minor heart attack. I was then given Praluent, and my gosh, what a savior! Cholesterol levels down to recommended levels and no side effects. I would probably say, without exaggeration, that this drug saved me!"

• Doone
• Taken for less than 1 month
• August 4, 2019

"I have only been taking this medication Praluent a short time so I can't say whether it has helped reduce my cholesterol. What I don't like about this drug is that it makes me feel nauseous and I sweat profusely which is upsetting and embarrassing as I work part time at a store as a dressing room attendant or a cashier."

• mick
• Taken for 2 to 5 years
• May 12, 2020

"I started on praluent 3 years ago not long after it was first introduced in the uk , after over ten year of on off , mostly off statins , due to there almost crippling side affects this drug has been a god send my cholesterol is below recommended levels for the first time ever for two years in a row, after having stents and one heart attack i now feel for the first time in years I'm no longer waiting for another imminent episode!. side effects, a few muscle aches but nothing like the statins and only last a short while.easy to take once every two weeks"

• juni
• Taken for 2 to 5 years
• June 23, 2024

"I have stopped taking injections which were every 2 weeks. I have itching all over, tingling all over, mouth ulcers, walking problems, pains in legs. I am passing urine more often. I have stopped only 4 days ago. I told the doctor who gave this to me, and he said to stop taking it and see what happens. I have to have a second blood test (full one) next week as the first one was incorrect or had queries. I have been taking this medication for approximately 2 years now. Although it brought my cholesterol right down, I feel I can control it with diet as it's not worth the effects I am having. I have read it takes up to 100 days for it to clear the system."

• Roman
• Taken for 6 months to 1 year
• March 17, 2024

"I've been taking Praluent 75mg for 9 months. I had experienced serious back pain after the 2nd shot for at least a week. After that, there were no side effects. Most importantly, this drug lowered my blood pressure, so I didn't need to take additional medication I had been on for years! LDL showed 100 less after 2 months on it. Recently, I had to switch to Repatha due to the fact that my insurance no longer supports Praluent. I have plenty of side effects and needed to take blood pressure medication as well. Praluent is way better, even though they are saying it's the same agent."

• Meano
• October 11, 2018

"I have had two shots getting ready for my third not sure if I want to take it because I've had chills, headache nausea a lot also aching. I'm going to get my blood test tomorrow to see if it's lowered it enough for me to keep taking this cuz the side effects for me are horrible. Also my blood pressure goes from being high to drastically low."

• Bon
• Taken for 1 to 6 months
• March 25, 2023

"Been taking 150mg of Praluent for 2 months now. The first month was perfectly fine, had no problems as I inject it in my thigh areas. However, I got a big welt and itching in that area from the third injection. I changed the injection site to my other thigh for the fourth injection and had the same side effect. Showed my cardiologist when I went in for a follow-up, but they did not seem concerned as levels were down. I’m allergic to all statins and had to try something, will continue if this is all that happens I can tolerate it with anti-itch cream. I will discontinue though if more side effects appear. Will see what happens in my third month. I’m 71 years old and have had 2 stents over 21 years. My high cholesterol numbers just jumped in the last year, possibly due to age as I’m a healthy eater, and I exercise three times a week. Will update again in 2-3 months."

• EdE
• Taken for 1 to 6 months
• June 6, 2018

"My total cholesterol has dropped from 268 to 125! The “all important” LDL (bad cholesterol) has been reduced from 184 to 50! Dramatic reductions in just 6 weeks on 150mg every two weeks. My HbA1c is essentially the same at 6.6 (was 6.7)...not bad. Kidney, liver- all stable and ok. No side effects at all with Praluent. Statins are toxic to my system--not just side effects, but toxic."

• biker
• Taken for 1 to 6 months
• December 23, 2022

"I have been on this for a month. Two injections so far. I am 64 years old, I exercise frequently, and have a history of cholesterol - total number under 200 however. Since taking this drug, I have been sluggish and fatigued. The fatigue comes and goes. Prior to taking this, I rode my stationary bike about 8 to 10 miles every other day. It is difficult to do what I regularly did prior to initiating this drug. Now, my exercise routine is tougher to do and I am very fatigued after riding. PSk9 inhibitors appear to have an impact on my blood pressure response to exercise. Hypotension response appears amplified (I am going for a follow-up on this). Research I have read on the PSK9's like this says, however, that the impact is "inconclusive" with respect to BP. However, I am more fatigued being on this drug. The first few days my cognitive abilities were impaired but this did improve. I also had more frequent nighttime urination. I am not taking a third Praluent injection."

• Anonymous
• Taken for less than 1 month
• June 8, 2023

"I took the first Praluent 150 injection and on the 3rd day after I got a terrible UTI. On day 5, I got severe body aches and muscle spasms. I’m on my second antibiotic for the UTI. I went to the doctor once and 5 days later ended up at the ER. I’m supposed to take my 2nd injection on Saturday but that won’t be happening. I’m just hoping my body gets back to normal soon. The Praluent injection was worse than Crestor or Lipitor for me."

• Mark...
• Taken for 2 to 5 years
• January 6, 2024

"This stuff rocks! Melted my impossible cholesterol down -200 points after being on maximum statins. I could not get below 300. I’m now bouncing around under 100 every test. I did have to get 3 stents so this does not stop blockages but this is just my body. I have hyperlipidemia and Diabetes at 59."

• Susan
• Taken for 1 to 6 months
• May 1, 2024

"I’ve been on it since Jan 14 every 2 weeks. I did have trouble with the injector the first month, but I finally got it right and the injections are now fine. However, this last month of doses, I’m having side effects. I have a bladder infection (positive results). I’ve had a very sore throat with drainage for 2 weeks after the last dose with a very severe cough. It started to go away but is back after my last dose 1 week ago. I feel lethargy and have a bad headache. I question whether these are side effects of the med!"

• Crono
• Taken for less than 1 month
• December 23, 2020

"Switched from repatha to praulent due to insurance. I injected first of the month. Now after 2 Er Visits and a bunch of prednisone, it's finally starting to leave my body. To recap. The next day I felt like I got hit with the flu and had no energy and felt like crap, shorty after my whole face, fingers and feet blew up and I has covered in hives, from head to toe. I'm a day done with my steroids and the hives are already coming back. Not as bad, but enough to be bothersome, especially during bed time. If you have any sensitivity to statins, I highly suggest you stay away."

• Lon
• Taken for 1 to 6 months
• July 20, 2018

"After 15 years on statins I could not accept Iiving with the continuous aches and pains. After three months on Praluent I feel fine, no noticeable side affects, no problem with injections. Cholesterol numbers reduced dramatically."

• Jrano
• Taken for 5 to 10 years
• January 24, 2019

"Awesome stuff for me. No side effects. Cut the pravastatin in half 40mg pravastatin 1x daily plus 75mg alirocumab every other week HDL down from 399 to 85mg dl. Still taking the other stuff. Livolo works fairly well but not like this. Can't tolerate ACE inhibitors and some med put a bruise across my back within three days. instant kidney damage. Now blue cross wants to deny me the only med combo I could tolerate. Actually prime theraputics is doing that. Forwarding their denial to cardio and via my atty to oag and state insurance board. After one 4x cabg 3 stents 2 mi. Bilateral endarectomy and original LDL around 400. I think my widow will be a millionaire as for ME.. we can prove this is the best and most correct treatment plan and it did work for about 5 years until they decided they should play doctor..."

• Kiki
• Taken for 1 to 6 months
• April 22, 2024

"I have had a good experience with Praluent and although my cholesterol has come down significantly, my provider increased my dose to get my LDL lower because I have a high calcium score. I had a rash around the injection site with the first few injections and my face would get really flush but that didn’t happen with the last injection, so my body must be getting used to the injection."

• Mike...
• July 14, 2016

"I couldn't tolerate statins. Tried 3. Each one gave a lot of pain....liver and angina. I had to stop them. While off them for a month my Total Cholesterol went from 165 to 213, LDL's went from 65 to 110. Now my Total is 97 and LDL's are 24. I take Lovaza to keep my HDL's up at 45-49; they never were above 34 my whole life no matter what I tried. I have no side effects and I feel the best in 5 years."