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Humira for Plaque Psoriasis User Reviews

Rating: 5.8

Humira has an average rating of 5.8 out of 10 from a total of 37 reviews for the treatment of plaque psoriasis. 49% of reviewers reported a positive experience, while 41% reported a negative experience.

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Reviews for Humira

Commonly mentioned side effects
  • 216...
  • Taken for 1 to 6 months
  • September 14, 2013

"After only 4 weeks of treatment with Humira for my plaque psoriasis, my skin is almost completely clear. I had large patches on my scalp, left upper arm, both elbows, and knees, and had spots all over my body like chicken pox. I feel amazing, and I am not in pain anymore. It's a miracle. I haven't experienced any side effects, and the injections don't hurt that bad. I love it!"

10 / 10
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50 Report
  • Jos...
  • April 26, 2016

"I never do these things, but I wanted to share my experience with everyone. In 2013, I was diagnosed with plaque psoriasis. Ointments helped at first, but eventually, my condition became worse. My self-confidence was at an all-time low, I couldn't go outside without feeling embarrassed. My doctor recommended Humira. I have been on Humira for about 5 months now. I saw results in the first week. I was almost completely clear, I couldn't believe it. As time went on, my condition started improving day by day. Today, I'm completely clear! I can't express my gratitude toward this medication enough. I haven't had any side effects in the five months I've been on it (knock on wood). I feel great and look great once again! Do it!"

9 / 10
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32 Report
  • Al ...
  • June 29, 2014

"I've had moderate psoriasis for over 30 years, also severe pitting and deteriorated finger and toe nails, swollen fingers and toes. After 1 year on Humira, I was 95% clear, including my nails. I'm still doing good on Humira after 4 years. I'm probably 80-85% clear and no scalp psoriasis at all, which was really bad. I use the pen for injections. I know eventually it will lose its effect, and then I'll move on to something else. But for now, it's shorts, tank tops, and a crew cut."

9 / 10
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34 Report

Frequently asked questions

  • Sum...
  • Taken for 1 to 6 months
  • November 11, 2014

"I was diagnosed with plaque psoriasis this year and was started on Humira shortly after the diagnosis. I cannot be more pleased with any other medication! Within 2 months, my skin was completely clear and itch-free! No more redness or scaling. Humira is a miracle."

10 / 10
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25 Report
  • Dro...
  • November 27, 2015

"I read about all of the bad experiences with Humira, and I never thought it would happen to me. A week after taking my first Humira shot, I woke up with a horrible rash. This was no normal rash, my whole chest and back were broken out, and it was burning. I took Benadryl and went to work. Throughout the day, the rash continued to spread over my whole body. I developed a butterfly rash on my face, and very little sunlight was burning me. I went to the ER, but they didn't know what to do, so I went to urgent care, and they gave me prednisone. The rash has cleared some, but I still have it. This was horrifying, I will never take it again, and you better believe this could happen to you!"

1 / 10
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20 Report

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  • Rea...
  • Taken for 1 to 6 months
  • January 29, 2016

"I have had psoriasis since I was 20 years old. I am now 35. I started using Humira about 2 months ago, and when I look at my skin now, I want to cry from joy!! It's gone!! All of the psoriasis is just GONE!! 15 years I have had people look at me weird and think I am diseased, now I look like any other person with clear skin. It is wonderful, and I want to hug the makers of this amazing medicine!"

10 / 10
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19 Report
  • Nic...
  • July 22, 2016

"I was on Humira injections for one full year. My psoriasis completely cleared after three months, however, I did develop a couple of side effects. The first one came when I started having trouble with my left knee. I had been administering the medicine in my thighs, alternating each thigh as instructed, but developed tendinitis. I couldn't administer the injection into my stomach due to severe scarring, so my only option was my thighs. It seemed to subside after the 6th month. During my 8th month on Humira, I noticed terrible stomach pains. I gained 15 pounds in only 8 months and started having gallbladder attacks. A few months later, I discontinued my Humira and haven't had any more digestive problems. Psoriasis is back with a vengeance, though."

5 / 10
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16 Report

More FAQ

  • Eri...
  • Taken for 1 to 6 months
  • May 22, 2023

"Not the best experience. After a few months of using Humira, I had to have my knee drained 3 times, typically after an injection. My psoriasis moved under my nails for the first time in 30 years. My body is covered in cysts on my back and on the side of my arms. None is noticeable, just to the touch. I wouldn't take it again even if I was paid."

1 / 10
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5 Report
  • Anonymous
  • Taken for less than 1 month
  • December 3, 2020

"Be very careful using this drug, and do not let your clinician talk you into it unless you have a very severe case of psoriasis. My son took this drug and immediately developed neuropathy in his legs and hands. It did not go away, and we eventually had to spend over 100,000 getting IVIG treatments to help. They did help, but he still has a low level of neuropathy left in his legs. This drug has also caused lesions on people's spinal cords. BE VERY CAUTIOUS USING THIS MEDICATION. BE forewarned, if you have a problem with this drug and call the company, they will cut you off and offer NO help. They do everything they can to keep you on the drug, but if you have a side effect, they are nowhere to be found."

1 / 10
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10 Report
  • SND...
  • Taken for less than 1 month
  • July 26, 2020

"My husband had really severe plaque psoriasis on his elbows, knees, legs, and head. After 2 treatments, his skin looks AMAZING!!! His legs haven’t looked this clear in years. He always wore long sleeve shirts to cover his elbows, and now he wears short sleeve. It has done wonders for his self-esteem."

10 / 10
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11 Report
  • Seb...
  • Taken for less than 1 month
  • August 29, 2019

"I suffer from plaque psoriasis and rheumatoid arthritis in my knee. I’ve been on and off Humira for about a decade now. This is the only drug that helps with both, and it is quite amazing. I see results literally within one week. I highly recommend this drug to treat the above defects."

10 / 10
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9 Report
  • Anonymous
  • August 9, 2016

"I was on the drug for about 6 months and had no side effects besides pain during the drug injection. My plaque psoriasis completely disappeared within the first 6 weeks and continued to do so until about 6 months later. No rhyme or reason, but it stopped working, and I'm in the WORST FLARE of my life. I've never had any issues with my hands or feet, but now that's my troubled spots. My hands and feet are severely dry and peeling, and the pain and itch are horrific. I'm using all the medicated ointments and creams that my dermatologist has prescribed, along with a new biologic, Stelara, and nothing has stopped the flare. I wrap my feet in Saran Wrap to help hold the moisture and medication in, and do the same with my hands with gloves. HELP!"

2 / 10
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12 Report
  • Lif...
  • Taken for 6 months to 1 year
  • May 14, 2020

"Started taking Humira in December 2019, and it has been a life changer for me. Psoriasis wouldn’t allow me to sleep. Now I sleep through the night. I had psoriasis for 20 years and finally did something about it. This has certainly been a life changer for me and a miracle drug."

10 / 10
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8 Report
  • Sme...
  • Taken for 1 to 6 months
  • January 6, 2020

"Horrible stuff - made me sicker than a dog. Fatigue, joint pain, and upper respiratory infections that I couldn’t get rid of - never had issues like that before. Every time I would do an injection, I would break out in lesions. About the time they would clear up, it was time for another injection. I wouldn’t recommend this to anyone unless you just enjoy feeling like death warmed over 24/7. Since I stopped this med, I feel SO much better - so far the psoriasis hasn’t returned, so I’m keeping my fingers crossed. What is mysterious is why the medical folks prescribing this junk are so unaware and in denial of the side effects."

1 / 10
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10 Report
  • Lan...
  • July 24, 2018

"I started taking Humira when I was around 14-15 years old. I have now been on it for 7 years, and it really does work. I have been 100% clear since taking it, and before I was basically covered. I have been monitored closely, and I get blood work every 6 months, and nothing has ever been wrong, I never get sick. I have decided to stop taking it just recently because I get very chronic, long-lasting, horrible Candida infections that I know are caused by my Humira lowering my immune system. Antifungals really don't work for me anymore, and it has become a constant battle. Switching to Cosentyx and hoping that solves my problem and still causes my skin to stay clear! But overall, Humira has been great and works well."

8 / 10
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8 Report
  • Bad...
  • Taken for 1 to 6 months
  • May 17, 2017

"Have had psoriasis for 30 years. I had a bad episode of plantar fasciitis, then the psoriasis affected my feet and lower legs really badly. So, after fighting for three months, I finally got 80 percent paid by Humira, and it must go through your insurance on the medical side. My Jehovah's got the copay, I am lucky. After a few months, I am almost completely healed. Nothing but a big round, looks like a burn spot. No creams, no lotions, and potions."

10 / 10
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9 Report
  • Unh...
  • April 19, 2017

"Did not work for me, caused worsening of psoriasis. I developed psoriasis lesions in areas I never had before. Very dissatisfied, I was hoping it would really help since I read a lot of successful stories. I have had psoriasis for 23 years and treated it with topical steroids and moisturizers. Two years ago, I started Otezla, which worked for about 18 months. I started developing lesions on my hands. Then, after starting Humira, I developed lesions on the bottom of my feet and palmar aspect of my hands. Systemic medications have actually caused my psoriasis to worsen. If you can control it with topicals, avoid systemic medications. I am regretting taking these medications, there is no going back now. Now topicals don't work at all."

1 / 10
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7 Report
  • Rai...
  • Taken for 1 to 6 months
  • July 25, 2019

"I have been on Humira for over 5 months. I am not seeing any improvement. It looks like one big red blob on both upper and lower legs. In addition, I have gained 15 lbs. I got psoriasis from taking Harvoni."

1 / 10
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5 Report
  • Suz...
  • Taken for 1 to 6 months
  • July 24, 2018

"So far, so good. Been on Humira for 4 weeks. I had plaque on the soles of my feet, which have cleared about 25%. I had tried Otezla in the past with no clearing at all. Still adding steroid cream and laser, but swelling, itching, redness, and plaques all show improvement. The injection is not that bad, just stings for a few seconds. I use the pre-filled syringe, not the pen, as people have reviewed it as less painful. I was hesitant to go on this due to potential complications. But my quality of life is so improving every day that it's been well worth it. Look forward to continued improvement in the next few months."

7 / 10
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5 Report
  • Gem...
  • August 14, 2018

"After taking Humira for 3 months, the plaques are a very tiny bit better but itch horribly. Unfortunately, I now also have pustular psoriasis, and the psoriatic arthritis that hadn't been too much of a problem is much worse. I don't know why doctors want patients to continue this drug when it makes things worse. I had about 50% coverage with plaques. Now I have about 30% pustular in areas I've never had it before - back, underarms, face, arms, hands, legs, feet. Psoriasis is truly a terrible disease. Western medicine needs to quit poisoning people and get to the root."

1 / 10
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7 Report
  • Kha...
  • Taken for 1 to 2 years
  • October 11, 2019

"Humira is a wonderful medicine. I am 99% free of my psoriasis with almost no side effects. The support from the Humira people has been tremendous. I’ve been on it for 14 months. My only problem is with my dermatologist, who switched me to the citrate-free, without my asking. My problem is with the thinner needle. It takes a few seconds longer to inject, and timing is critical. My track record with the old needle is way better. Still adjusting."

10 / 10
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4 Report
  • Seb...
  • November 5, 2019

"Psoriasis and psoriatic arthritis: after years of unsuccessful treatments, Humira was 99-100% effective, completely clearing my skin and freeing me from arthritis. I was taken off Humira and put on Imraldi: skin still clear, but arthritis returned. As a drum teacher, this is alarming. Pain significant; decreased joint mobility already affects me. I had fatigue and headaches with Humira. But weighed against benefits, they're tolerable. Imraldi leaves me more fatigued; headaches more intense and persistent. I looked forward to Humira. I dread Imraldi. Big, clunky needles are flimsy, breaking when used, failing to deliver medicine. I swapped to Imraldi pens: first failed; second worked but left a bruise on my leg (fortnight to clear). Tonight's dose failed. I want back on Humira; quite literally a lifesaver. I'm contacting the manufacturers of Imraldi to let them know my experiences. Hopefully, they might improve the medicine and its delivery methods."

10 / 10
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4 Report
  • Suz...
  • Taken for 1 to 6 months
  • September 6, 2018

"8 weeks on Humira. For 4 years, I have had plaques on only the soles of my feet. I finally decided to try Humira after no results with Otezla. Now it's on one of my legs and one of my arms too, and it did nothing for my feet, worse if anything, and itching is still terrible. Do not recommend this drug. I am switching to Cosentyx."

1 / 10
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5 Report
  • Awf...
  • Taken for 1 to 6 months
  • July 8, 2017

"Shots were painful, made my psoriasis worse, developed plaque on palms of hands and bottom of feet, and made other areas worse. Since stopping it, have started Taltz, which is helping, but these lesions are very resistant to treatment. I went from having a mild case of psoriasis to severe. I regret starting to take biologics and should have stuck to topical medication. Advice: do not start them if you can deal with them with topicals. You become dependent on them, and then they stop working, and you have to go on to a new drug with many potential side effects."

1 / 10
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6 Report
  • Bec...
  • Taken for 1 to 6 months
  • April 30, 2023

"I tried Humira, and I only had psoriasis on my feet and hands. Now I'm covered with psoriasis from head to toe after my third dose. I feel terrible and have quit going to the gym because I'm so embarrassed by the way my skin looks. I wish I never took any of the shots. Ozempic made me have dry heaves, and now my doctor wants me to try Skyrizi. I wish I never took anything and just did the tanning booth for my feet and hands. I have it now everywhere."

2 / 10
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1 Report

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