Acyclovir and Pain: What Users Say

• ano...
• March 4, 2016

For Herpes Simplex (HSV) "I was diagnosed with HSV-2 five years ago. I had hardly any symptoms until now. I was not in a sexual relationship, but this week I had sex after my menstrual cycle. I had my first outbreak, it was horrible. I felt so depressed. I had all kinds of blisters in private places. Very, very painful, it was hard to walk, sit, sleep, and go to the bathroom. I searched the web for treatment. First, I tried tea tree oil, that was too harsh down there. Then I took 6,000 mg of Lysine, that did not help at all. Took 3,000 mg of vitamin C, nothing. I felt that white vinegar helped a bit, and cornstarch was soothing. I took 2 Epsom salt baths a day, and that was soothing also. The only thing that helped was Acyclovir, all symptoms went away right away."

• kat...
• January 13, 2016

For Herpes Simplex (HSV) "I have been on Acyclovir for 3 days following a first outbreak of genital herpes - having never suffered with anxiety or depression, I've been crying about an hour after taking each pill. Feeling anxious, depressed, sweating, abdominal pain, short-tempered, and very nauseous. Mood swings aren't in the side effects but they should be, as countless other people on similar forums have experienced the same."

• Sad...
• Taken for less than 1 month
• June 10, 2019

For Herpes Simplex (HSV) "I became very irritated down there to the point it hurt to go to the bathroom. I scheduled an appointment for the doctor, and they told me I had a yeast infection. I then noticed bumps down there, and they tested for HSV2 (herpes simplex 2) that came back positive. Currently, day 3 of acyclovir, and I am so happy to almost be back to myself. The pain I went through was unbearable... had to call out of work several times because I could barely walk. We will see how this medicine works for me over time."

• Slo...
• August 8, 2019

For Herpes Simplex (HSV) "So I am 65 and haven’t had an outbreak for 4 years. In the past couple of days, I’ve had a burning sensation that comes and goes. It’s in a different place than I’ve ever had it. There is absolutely nothing to see, no blisters or sores. But it is so tender I’m lying around with ice on my crotch. My jean shorts were painful to the area. I have the Acyclovir on hand, but how do I know if it’s a herpes outbreak? It almost feels like it’s bruised. Again, nothing visible. Is this a giant outbreak waiting to surface? Is it harmful to take a course of it “just to be safe?”"

• Hor...
• Taken for 10 years or more
• April 12, 2020

For Herpes Simplex (HSV) "I was prescribed this medication, and it did work. Years later, I'm still battling with this virus. I never gave it to anyone. Anytime I feel discomfort, I call my doctor to send a script to the pharmacy. I have had an outbreak on different parts of my vagina and by my anus and mouth. The ones that come by my vulva or anus are the worst, especially when I urinate. I always have that cup of water to pour while I urinate so it wouldn't burn. I'm having an outbreak now. I've been feeling this itch and painful feeling that got me up. I took a pill about 30 minutes ago. I can honestly tell you I'm feeling the medication kick in. My pill is 500 mg. I try to keep some on hand for times like this. My doctor is close."

• Anonymous
• February 21, 2009

Zovirax (acyclovir) for Herpes Simplex (HSV) "I've been taking this medication for about a week and can still feel some pain, but other than that, it works really well. I've been taking 400 mg three times a day."