Acetaminophen / oxycodone and Constipation: What Users Say

• Ton...
• July 9, 2021

Acetaminophen / oxycodone for Chronic Pain "I've been taking Percocet 5/325, 1 and 1/2 times a day for a totally messed up lower back in constant levels of pain when moving. Can't stand up straight for 10 yrs. I also periodically get back injections and take small amounts of Methocarbamol for spasms, plus occasionally Diclofenac when extremely bad. I know for a fact I will never get addicted to the Percocet. I don't feel any 'high' or crave it ever. In fact, it makes me nauseous and constipated. Oddly enough, that little bit, spaced right, combined with other pain relief, allows me to get around pretty good, take care of grass cutting, etc. It does cut into the most severe pain, for example, Sciatica, when that flares up. And to be honest, it's safer than any other alternative, especially for those of us who never crave the feeling of the drug!! To be honest, it's overall NOT a physical feeling of well-being for me! It cuts into pain.. PERIOD!"

• PAI...
• Taken for 6 months to 1 year
• May 1, 2023

For Chronic Pain "Been taking pain medication for many years. Some have helped and some not. Recently, I feel the pain meds are lacking the main ingredients that help. It is so frustrating that people who really need pain meds can’t get them without being made to feel as if they are an addict. I believe that pharmaceutical companies are cutting back on ingredients because of so many overdose cases. That has really hurt the people that really need good pain medicine. This company that my prescription was filled through, Alvogen pain med company, must have forgotten to put the main ingredient in the pills. All the pills did was give me major constipation. Little relief from my back pain. They made a lot of money for selling people false medicines. Help. Help. Help."

• tip...
• August 30, 2009

Acetaminophen / oxycodone for Pain "To anyone who has used or will use Percocet, for the nausea, have your doctor put you on a pill called Zofran. This will help with the nausea. They give it to cancer patients for vomiting. I am a huge believer in the mental help Percocet gives as well as the pain management. Had gallbladder surgery in May 09, and after trying Vicodin, Oxycontin, Dilaudid, Ultram, Percocet was the ONLY one that helped me with the pain. Eat before taking and drink plenty of fluids. This will cause severe constipation, so a stool softener may be needed. Best medicine I have ever taken."

• BEW...
• April 29, 2018

For Chronic Pain "CAUTION: pills 10/325 by CAMBER. Side effects have sent me to my doctors and ER. These pills caused burning of the lining of my mouth and throat, etc. The first pill taken had a very bad chemical smell and a chemical taste. It started to dissolve in my mouth right away, it got stuck in my throat. I have a paralyzed vocal cord. I felt it burning away and the god-awful taste. My other side effects of this pill have left me with nausea, massive headaches, etc. My throat is still swollen and I could not eat. The burning in my mouth and throat is still there and my stomach is still sick. I had to stop taking this pill. At first, I thought I also had the flu and got so constipated. So far, all medical tests taken to show strep throat, etc., show nothing. The doctor and ER say there is a burned look to my mouth and throat with redness. I still taste and smell that pill. I have had to go without my pain meds. I have filed a report to the FDA and will consult with an attorney."

• Kus...
• Taken for 2 to 5 years
• April 23, 2017

For Chronic Pain "I have a spinal cord injury. I have been on 10/325 for over 2 years now. Certain brands work better than others. Generics don't contain the exact same recipe as each one. So far, I have experienced 3 different ones. Amnea marked with IP204 are by far the best pain relief ever. Endo, which are yellow (and I don't have my old bottle), are worthless for pain relief, these gave me the runs majorly. Mallinckrodt Pharm is the new ones I just got, and they are not taking the edge off the pain and giving me horrid constipation. Unfortunately, if you are a pain patient, you are labeled as an addict, so telling your doctor that the pill doesn't work is worthless. Ask the pharmacist before what kind they have and let them know what ones work for you!"

• Wom...
• Taken for less than 1 month
• April 30, 2016

Acetaminophen / oxycodone for Pain "I was prescribed this for pain following brain surgery. Take with food to prevent nausea. To avoid constipation, I took each dose with a stool softener and drank apple juice. Works good on the pain. But you do feel a little loopy on it."

• Anonymous
• Taken for less than 1 month
• November 25, 2016

Acetaminophen / oxycodone for Pain "I have an infected tooth with a dead nerve that needed a root canal. I got half the root canal done and need to wait for the infection to clear up. I'm taking major antibiotics, but it's still taking a while, and I'm in a lot of pain. The Percocet has helped immensely. I waited too long to take it last night and had to take a trip to the ER for morphine! The morphine was not much different than the Percocet. My problem was that I waited. I have been taking one every 6 hours, which is said on the bottle, but I think I need to do it every 5 hours. Hopefully, that's okay to do. I'm also on 800 mg of ibuprofen every 6 hours. I have not experienced any nausea, but yes, I guess I am constipated, but I have only been eating soup anyway."

• Hai...
• Taken for 5 to 10 years
• April 15, 2016

Acetaminophen / oxycodone for Chronic Pain "I take them for back pain, and for an ACDF surgery. I take them 4 times a day, and they are great. But your body will build up a tolerance over time. But until then, they work so well! Takes some time to kick in though. And will make you constipated. But for pain, the side effects are worth it!"

• bor...
• Taken for less than 1 month
• February 9, 2018

Acetaminophen / oxycodone for Pain "Was prescribed generic 10/325 after wisdom teeth removal, and it made my recovery a breeze. Took one on a timer a few times a day, as advised by my surgeon, and it almost completely erased the pain. Only downside was that it wore off extremely suddenly (at least for me), so if I missed a dose, I'd be met with excruciating pain around the 6-hour mark. I had no side effects other than constipation (which was easily taken care of by an OTC laxative) and pretty extreme drowsiness. I didn't mind that, though, because I needed the rest to properly recover anyway."

• Kdo...
• July 16, 2010

Acetaminophen / oxycodone for Pain "I have herniated discs in my lower back from a fall. I generally don't like taking narcotic pain killers, but it gets to a certain point where I would take anything to make the pain stop. That's when I take one 5/325 Percocet. It takes 90% of my pain away when I take it with Motrin. I've tried every non-narcotic pain reliever and had no results. I tried Ultram with high hopes, but it didn't help. It's a shame that because of abuse, this medication is so frowned upon (and hard to get even if you really need it). It's so helpful for me and gets me through days that I would otherwise spend crying or in bed. The only downside is if I have to take it a couple of days in a row, I get constipated. I have no dizziness, high feeling, or nausea."

• Wef...
• Taken for 1 to 2 years
• December 27, 2017

Acetaminophen / oxycodone for Chronic Pain "With degenerative disc disease (DDD) and previous broken back arthritis, worn-out hip, I can't work without this med. It's what keeps me in the workforce. I get constipation, but eat fruits to counter that. I take as directed, too much clouds thought process."

• New...
• Taken for 6 months to 1 year
• December 11, 2015

Acetaminophen / oxycodone for Pain "I was prescribed this medication after vaginal birth, 30 hours labor, and a significant episiotomy. Medicine was a life saver. I have a very low pain tolerance and had almost no pain while taking this medicine. The cons were that I was extremely constipated and mentally was very out of it and even had some light hallucinations."

• bis...
• December 6, 2010

Acetaminophen / oxycodone for Pain "When I first began taking Percocet 5/325 for disc protrusion L5-S1, I became very constipated. My doctor prescribed Polyethylene Glycol, a powder for oral solution. This is Maalox, and it has been a Godsend for me. I am no longer constipated since about 6 months ago. Just take it as prescribed, and it truly works."

• Me...
• May 21, 2016

Acetaminophen / oxycodone for Pain "My Rx 5/325. I had bilateral total knee replacement 12 weeks ago. Taking this totally helped me make it through this recovery period so far. I now take less than one a day and try to use ibuprofen instead. My side effects did not outweigh the benefits, but as you can see from reading the reviews, everyone has a different reaction. Mine are: constipation, so I took a laxative or suppository, slow reaction time, be extremely careful if you have to drive, if you can avoid driving, impaired/cloudy thinking, restlessness. When I go back to my desk job, I can take this during the day, but if you take it at night, you may not sleep well. I plan to continue to taper off and use only when pain level is above 5. Ibuprofen nighttime works better for sleep."

• per...
• February 22, 2011

Acetaminophen / oxycodone for Pain "I have severe back pain and leg pain associated with sciatica. The MRI indicates a central and left herniated disk between L5-S1 and annular disc bulging at the L4-L5 level. I tried every over-the-counter pain medication and Tramadol, which did nothing. The pain in my back, left buttocks, and left calf was debilitating. I could not put on a pair of socks, let alone do any normal activity. My doctor then prescribed Percocet, and I have to say this drug is a Godsend. It actually has given me my LIFE back! I never get a 'high'-there is no feeling of euphoria-what I do get is RELIEF of my pain so that I can actually work, play, and live. Side effects: constipation. I eat bran cereal twice a day-gone. I get insomnia at night, so I take smaller amounts."

• Nam...
• Taken for 5 to 10 years
• October 18, 2017

For Chronic Pain "10/325 - I’ve taken this medicine for about 5 years. I have spinal stenosis, scoliosis, bulging discs, degenerative disc & joint, bone spurs on my back, hands and wrist, arthritis everywhere you can have it, etc. I will be having both knees replaced. I’m in constant pain. I take my medication four times a day as directed, and they help me very much. I have only one side effect, and that’s constipation. I use Miralax for that, it takes longer to work, but it’s a small price to pay for the relief I get."

• szq...
• January 9, 2011

Acetaminophen / oxycodone for Pain "For nerve injury, I was taking Lyrica and Vicodin - the only combination that helped (after much trial and error). Then, I had ended up with surgery (ovary removal), and the doctor prescribed Percocet 5-325. It is a wonder medicine. The first day, slightly nauseous, but that quickly went away. I now prefer the Percocet; it doesn't make me as sleepy as Vicodin. I break pills in half, spreading them throughout the day to just dial down the pain enough for me to be cheerful and productive but not zoned out. I gave it a 9 out of 10 because it does cause constipation (take Colace OTC)."

• Mar...
• November 27, 2015

Acetaminophen / oxycodone for Pain "Prescribed this after impacted wisdom teeth extractions. Eased pain a little, but the headache, sleeplessness, constipation, jitters, and persistent nausea aren't worth it. Ibuprofen works much better without any side effects."

• Loo...
• Taken for 1 to 6 months
• July 8, 2016

Acetaminophen / oxycodone for Pain "My doc prescribed this for after having colitis. It dulls the pain, but for 2 months had the worst constipation (with Colace) and groin pain I ever had in my life. Went to 5 docs and had over $1500 in CT scans and ultrasounds for pain. Doc misled me and said to take it 24 hours a day. After about 2 weeks of agonizing pain, I came off it on my own. NO PAIN! Be very CAREFUL."

• Anonymous
• August 19, 2012

For Chronic Pain "I have 12 bulging discs from my neck to lower back. Medicines work good but only for a couple of hours, not the 6 hours the doctor expects it to. I take 4 a day now, but to honestly live a comfortable life, that should double. I have also taken other medicines like Opana ER. If the doctor would combine the two medicines, I could live a pain-free, normal life, but they won't. With taking these medicines 4 times a day, I average a pain level of about a 6 or 7 daily. Doesn't have any side effects on me except sometimes constipation."

• Ott...
• Taken for less than 1 month
• February 4, 2018

Acetaminophen / oxycodone for Pain "Feb 2018 I don't like taking strong meds. I developed horrible upper thigh leg spasms from a pinched nerve in my back. Couldn't sleep, terrible pain. Doctor gave me Oxycodone 325...wonderful meds. No pain after 1/2 tab. Yes, dizziness. Take with Metamucil to avoid constipation. Drink plenty of fluids. No other side effects other than a little tinnitus. Good job, researchers. Finally, a decent pain killer that doesn't rot your stomach! Like Advil and stronger than Extra Strength Tylenol. Wish the provincial government would cover it though."

• Anonymous
• August 25, 2009

Acetaminophen / oxycodone for Pain "I had all 4 wisdom teeth pulled about a week ago. I was prescribed fifteen 5 milligram Endocets for after surgery. I took about 5 the first day and then 3 the next and 2 the 3rd day and 1 the fourth day. It helped the pain, but not for very long. I took a nap every time I took a pill. I also found myself to have severe mood swings while on the Endocets. I was happy one minute then felt awful the next. Also, they gave me TERRIBLE constipation. If you're taking them, eat a lot of fiber or take a laxative or two a day to keep everything moving. Although for the short amount of time that they worked, my body felt awesome."

• Anonymous
• July 4, 2008

Acetaminophen / oxycodone for Pain "Post-surgery: I am sensitive to medicine, and this one is not too hard on my stomach. It helps me get comfortable enough to get a good night's sleep. It will cause hard stool or constipation. I have been taking one every night at dinner and two stool softeners in the morning with breakfast. Cannot take and work or drive, so only useful for nights. Overall, very happy with this."

• Anonymous
• July 4, 2008

Acetaminophen / oxycodone for Pain "Post-surgery: I am sensitive to medicine, and this one is not too hard on my stomach. It helps me get comfortable enough to get a good night's sleep. It will cause hard stool or constipation. I have been taking one every night at dinner and two stool softeners in the morning with breakfast. Cannot take and work or drive, so only useful for nights. Overall, very happy with this."

• sha...
• May 11, 2011

Acetaminophen / oxycodone for Pain "I've dealt with 'undiagnosed' pain for years. I've had test after test. All I know for sure is that I have severe cramping and diarrhea, as well as joint pain. I have also suffered from anxiety and insomnia. Percocet seems to resolve all of my issues in one dose. Unfortunately, I can't get a doctor to take me seriously. The side effects seem to be limited to a warm flush and constipation, which in my case actually makes me regular."