Skip to main content

Acetaminophen / oxycodone for Pain User Reviews (Page 3)

Brand names: Percocet, Percocet 10/325, Percocet 5/325, Percocet 7.5/325, Prolate, Percocet 7.5/500, Percocet 10/650, Oxycet Nalocet Percocet 2.5/325 Primlev Xolox …show all brand names

Acetaminophen / oxycodone has an average rating of 8.1 out of 10 from a total of 404 reviews for the treatment of Pain. 79% of reviewers reported a positive experience, while 11% reported a negative experience.

Reviews for Acetaminophen / oxycodone

  • Kaylei
  • April 20, 2013

Endocet (acetaminophen / oxycodone) "I was in a very bad car accident in 2009, needless to say I've been on pain medication since then and have been given everything from hydrocodone to fentanyl patches to OxyContin. I'm only 27 so its hard to be doped up and tired all the time. And it was either nausea or headaches all the time. My doctor put me on Endocet 10s about a year ago and they are the absolute best thing for my pain. My tolerance isn't rising quickly either. I'm very pleased so far with this medication, no negative side effects aside from very mild bathroom troubles."

8 / 10
Was this helpful?YesNo
47 Report
  • Reneke
  • Taken for less than 1 month
  • July 24, 2014

Endocet (acetaminophen / oxycodone) "I had endoscopic sinus surgery and took 80 pills in the first two weeks. The pharmacist made me feel like an addict, and made me so mad! Now my pain is reducing a lot, it has been three weeks since surgery and I use only one pill to make it through my work day. I have no side effects and do not want to get addicted, but it really helps A LOT with pain control and lets me function instead of cry and whine."

9 / 10
Was this helpful?YesNo
43 Report
  • Zacha...
  • Taken for less than 1 month
  • September 20, 2014

Percocet 10/325 (acetaminophen / oxycodone) "I was prescribed this medication for relief from "gallbladder attacks," until I could have my gallbladder removed. I have taken Norco 10/325 previously for a bulging disc. Percocet is far superior in pain relief, time between doses, and fewer side effects (in my opinion)."

10 / 10
Was this helpful?YesNo
42 Report
  • George
  • Taken for 10 years or more
  • August 25, 2019

"My issues are L-1 thru L-5 all bulged L-4 annular tear, arthritis in lower back. Took 10-500 hydrocodone with acetaminophen for 12 years, @ 3 a day then the laws changed and had to go every month for drugs at pain clinic where I told them meds only upset stomach didn’t help. So I was changed to oxycodone with acetaminophen 10-325 3xDay , along with epidural, facet injections, risotomy, and SI injections. I had no real relief and finally had a second opinion from a spine specialist that gave me Meloxicam 7.5 and therapy - no more opioids never any real relief from the opioids ."

Was this helpful?YesNo
25 Report
  • Chsrl...
  • November 10, 2016

Percocet 10/325 (acetaminophen / oxycodone) "I think endocet are the best pain medicine I have been on pain medicine for 15 years I have 3 crushed disc in my back and they can't operate because I have a bad heart I was driving 400 miles round trip to get them that is how much I think they are much better than any other brand"

10 / 10
Was this helpful?YesNo
34 Report

Are you taking this medicine?

  • Doitr...
  • July 30, 2014

Percocet 10/650 (acetaminophen / oxycodone) "You have to remember, with an injury pain can be your friend. I've been taking 10-650 for years off and on and just because it says to take once or twice a day doesn't mean you have to. Pain reminds you that the injury is still there and gives you limits that stop you from making it worse. "

9 / 10
Was this helpful?YesNo
41 Report
  • tdl
  • August 3, 2011

Percocet 10/325 (acetaminophen / oxycodone) "I was on different doses of Vicodin for 2 years and I was having pains in my side from all the Tylenol and damaging my liver. I was switched to Percocet and it has been awesome. I take 3 x 10/325mg a day and I have osteoarthritis and fibromyalgia. I am only 24 so it was hard to find a doctor who would actually treat and listen to me and not think I was a drug abuser because of my piercings, age and tattoos. This medicine decreases my pain my 80% and with my Voltaren Gel I can get 90% relief. I have a 5yr old daughter and without my medication I can't take care of her or myself. I just sat around crying all day in pain. Now I can cook, clean, do activities, go on outings, run errands and do everything I did before."

10 / 10
Was this helpful?YesNo
48 Report
  • Jazon
  • Taken for 1 to 6 months
  • April 9, 2015

Percocet (acetaminophen / oxycodone) "Prescribed for pain of a large ulcer on my foot, 10/325 x6 a day, it definitely provided relief until I recovered (2 months). Tapering and stopping was crummy but somewhat relieved by clonidine, neurontin and a short course of ativan. A potent pain med tho, definitely works!"

8 / 10
Was this helpful?YesNo
37 Report
  • ambere
  • September 30, 2008

Percocet 10/325 (acetaminophen / oxycodone) "I've had to be on it for about 7 years because of an auto-immune disease. I have deteriorating bones. It's the only medication that I have found that will at least make my pain bearable. It has been a life saver for me."

10 / 10
Was this helpful?YesNo
54 Report
  • Iphig...
  • April 27, 2018

"I take generic Percocet - 30@5 mg every 6 months so I'm not a heavy user. My former generic pills worked perfectly. Recently I had Walgreens fill the prescription & I discovered that their new manufacturer, cambra, has a product that turns blue , even when stored properly in the bottle, is less effective in controlling pain & causes stomach issues, headaches & nausea. I experienced these side effects, and a quick look where this pill was rated, the majority of reviewers reported similar reactions. I researched why the pills turn blue. ( I thought I had been given counterfeit pills or molded pills). A blue dye has been inserted to prevent misuse, but I can't see how that would deter them. I read the FDA as of 2017 will not approve of dyes for the pills due to reactions such as what I had., Why would a respected pharmacy like Walgreens carry such an inferior & potentially dangerous product? Many have reported these issues so I know they are aware."

3 / 10
Was this helpful?YesNo
27 Report
  • discp...
  • Taken for 6 months to 1 year
  • March 8, 2013

Percocet (acetaminophen / oxycodone) "Percocet seemed to be the only pill that would help me while I was dealing with the pain from 2 herniated discs in my back (pre- surgery.) Although it couldn't take even close to all the pain away, it did help significantly. I was taking 10mg/ 4 times a day, and I was still in significant pain, but it worked better than advil, hydrocodone, and dilauded. Now post- surgery, I only take it for breakthrough pain."

7 / 10
Was this helpful?YesNo
41 Report
  • Jimmy
  • October 1, 2021

Percocet (acetaminophen / oxycodone) "These generic brands are not working, I complain with pharmacy, doc, FDA, med watch , anyone that will listen, even call the head pharmacy of LSU in Louisiana, they don’t care! Idk what else to do! Hydro's don’t work either! I guess I go to heroin or find some fake pills from Mexico! Ha ha , everyone should file with the FDA , med watch, there doc , pharmacy, etc !"

1 / 10
Was this helpful?YesNo
14 Report
  • Anonymous
  • November 13, 2011

Roxicet (acetaminophen / oxycodone) "I was prescribed Roxicet 5-325 for pain relief after major abdominal surgery and I have to say this was amazing! I've never had such complete relief from any medication before. One tablet every 4 to 6 hours kept me completely comfortable. It made me a little sleepy, but that was fine given that I was recuperating from surgery. It would probably not be suitable for me to take while working. The only real side effect I experienced was a little nausea, which I learned to minimize by taking it with food. Overall, the most effective pain medication I've ever used."

9 / 10
Was this helpful?YesNo
43 Report
  • Robert...
  • May 22, 2008

Percocet (acetaminophen / oxycodone) "This pill is amazing. i just recently had nose surgury for the 3rd time due to breaking it playing football/boxing this time they had to go in and move the cartlige and befor they had me on Oxycodon and it helped out but now that they put me on percocet it has extremly been usefull. Its relived all my pain, helps me sleep and the side effects are not that bad."

10 / 10
Was this helpful?YesNo
51 Report
  • Agent...
  • December 29, 2008

Percocet (acetaminophen / oxycodone) "I was prescribed Percocet for a foot injury. It was a lifesaver. Percocet dealt with the pain and helped my mood at the same time. I have noticed others' comments about its help with mood, and I have concluded that there is a correlation to its efficacy and anxiety. "

8 / 10
Was this helpful?YesNo
49 Report
  • jglo
  • April 5, 2010

Percocet (acetaminophen / oxycodone) "I had oral surgery and was prescribed Demerol which made me feel sick not to mention I could still feel the pain somewhat. I.called the doctor who then prescribed Percocet 10/325. Not only did it knock out the pain completely but the side effects were practically non existent. Just a little sweating and and kind of a warm feeling but I could function like normally. I didn't feel out of it like the Demerol made me feel. All I can say is it worked perfectly for me."

7 / 10
Was this helpful?YesNo
46 Report
  • Anonymous
  • February 11, 2012

Endocet (acetaminophen / oxycodone) "Husband has been on Endocet for 7 years. It was the only narcotic pain reliever that works for him. He refuses to accept other generics as they do not work as well for him. I am sure body chemistry plays a roll in which med works for each individual. For him, Endocet is the best."

10 / 10
Was this helpful?YesNo
41 Report
  • Anonymous
  • Taken for less than 1 month
  • November 25, 2016

Percocet (acetaminophen / oxycodone) "I have an infected tooth with a dead nerve that needed a root canal. I got half the root canal done and need to wait for the infection to clear up. I'm taking major antibiotics but it's still taking a while and I'm in a lot of pain. The percocet has helped immensely. I waited too long to take it last night and had to take a trip to the ER for morphine! the morphine was not much different than the percocet. My problem was that I waited. I have been taking one every 6 hours which is says on the bottle but I think I need to do it every 5 hours. Hopefully that's ok to do. I'm also on 800 mg of ibuprofen every 6 hours. I have not experienced any nausea but yes,I guess i am constipated but i have only been eating soup any way."

10 / 10
Was this helpful?YesNo
28 Report
  • Stard...
  • November 12, 2008

Percocet (acetaminophen / oxycodone) "I am taking Percocet 10's 4 x a day for severe back pain (post 2 spinal fusions, sciatica in both legs and 3 knee surgeries). I am having a partial knee replacement in 4 weeks. This medicine works great, with only one exception, it causes severe sweating, mostly at night."

9 / 10
Was this helpful?YesNo
47 Report
  • mad...
  • Taken for 2 to 5 years
  • May 4, 2018

Percocet 5/325 (acetaminophen / oxycodone) "T/192 white round pill I got at Walgreens is fake, fake, fake not the real oxycodone 5/325 - well it definitely doesn't work!!! I usually get my meds at Walmart and I've have never seen any meds like this."

1 / 10
Was this helpful?YesNo
22 Report
  • Woman...
  • Taken for less than 1 month
  • April 30, 2016

Percocet (acetaminophen / oxycodone) "I was prescribed this for pain following brain surgery. Take with food to prevent nausea. To avoid constipation, I took each dose with a stool softener and drank apple juice. Works good on the pain. But you do feel a little loopy on it."

8 / 10
Was this helpful?YesNo
27 Report
  • Anonymous
  • March 23, 2009

Percocet (acetaminophen / oxycodone) "I was having terrible back pain from my degenerative disc disease. I started off taking tramadol(ultram), then they switched me to Percocet. That changed my life. After taking it for a few months I could drive again. Now I can go where I want with little or no pain. I still have pain when shopping, which I hate anyway."

10 / 10
Was this helpful?YesNo
43 Report
  • rholl...
  • October 5, 2009

Percocet (acetaminophen / oxycodone) "I have been on Percocet about two years ago for degenerative disc disease. It helped a lot, but it can be habit forming. Be very careful with this medicine; take ONLY as prescribed, and it will help you."

8 / 10
Was this helpful?YesNo
41 Report
  • Londawg
  • Taken for less than 1 month
  • January 6, 2022

"Percocet 10/325 (acetaminophen / oxycodone) for Pain: I am hoping to start a discussion about manufacturers. I have this from Amneal Pharma and it sucks. Someone else posted that they had Camber and it sucked but the one from Mallinckrodt is good. I have another med from Camber and it is also bad and switched it to Aurobindo and had no issues. For all of you let's post the manufacturer of the RX you were given. It will be listed on the bottle. Maybe we can find out who to avoid."

7 / 10
Was this helpful?YesNo
11 Report
  • farmer...
  • Taken for 1 to 6 months
  • February 6, 2016

Percocet (acetaminophen / oxycodone) "I recently had a 9 mm and 7 mm kidney stone between my kidney and bladder. Too large to pass so I had to have a stent placed to prevent blockage while waiting a week to go back for the procedure to break up the stones to a passable size. I had been given several types of pain meds through I. V. While in the hospital including some that were very powerful including duladid among others. I was sent home for 5 days while waiting for the procedure and was given percocet 10 / 325 1 every 4 hours. Without it I couldn't have tolerated the pain. Also had very limited side effects, nothing like what the I. V. Meds caused and I felt much safer taking it vs the other more powerful meds. I would recommend this to anyone suffering from kidney stones"

10 / 10
Was this helpful?YesNo
27 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.