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Acetaminophen / oxycodone for Chronic Pain User Reviews (Page 5)

Brand names: Percocet, Percocet 10/325, Percocet 5/325, Percocet 7.5/325, Prolate, Percocet 7.5/500, Percocet 10/650, Oxycet Nalocet Percocet 2.5/325 Primlev Xolox …show all brand names

Acetaminophen / oxycodone has an average rating of 5.5 out of 10 from a total of 382 reviews for the treatment of Chronic Pain. 45% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Acetaminophen / oxycodone

  • Chelle
  • January 30, 2019

"I refilled my pain medication prescription and it is not effective The pills looked different so I called the pharmacist who informed me the manufacturer has changed in the last week or so and now they have the Mallinckrodt Pharmaceuticals brand. I took one and waited an hour and a half, it did not work, then I took another. I am still in considerable pain and unable to sleep. My medication is usually effective. It is a strong dose and I do not want to increase the amount nor the dosage.: They told me the manufacturer was changed by Walgreens and they have no control over who they purchase from, The staff is wonderful, there are no issues with the staff. As a consumer, I am notifying you that the new supplier product is not effective. I appreciate your help. I have been a loyal Walgreens customer and would hope to have issues resolved other than change pharmacy My medication is the Mallinckrodt Pharmaceuticals Oxycodone 10/325 The pill is white and has writing one side 10/325 and on the other M523. The pills I took previously from Walgreens were an off white yellowish"

1 / 10
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  • rme
  • September 17, 2013

Endocet (acetaminophen / oxycodone) "I have Fibromyalgia and I have taken Oxycodone for when I am having a bad day and my Fibromyalgia flares up. It helps me have a better life. I can get up and move. This medication takes the edge off for me. It does not take all the pain away, which is okay because I just want to be able to function rather than staying in bed or on the couch all day, unable to get up due to the pain."

9 / 10
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  • Dissa...
  • Taken for 5 to 10 years
  • July 18, 2019

"I've been taking acetaminophen with oxycodone 10/325 for the last 10 years for my chronic condition, and these Camber made pills seem to have half of the oxycodone in it since I have to take more to achieve the relieve I've received from other generic brands. Also, having taken more it's made me more restless than relieved, and it's completely thrown my managed consumption amount so I hope I have enough for the entire month. Now I'm stuck with these until my next fill!!"

1 / 10
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42 Report
  • petunia
  • Taken for 2 to 5 years
  • January 31, 2013

Percocet (acetaminophen / oxycodone) "I have arthritis in most joints, especially in spine, degenerative disc disease & now spondylolisthesis (vertebrae slipping onto next vertebrae - bone against bone). MD just upped my Opana from 10 to 20 mg, 5mg Xanax 3x a day to calm me (no change) & switched from Oxy IR 10mg 6-8 hrs to Percocet 7.5 6-8 hrs due to pain increase. What a difference! I feel able to do the things I like/need to do. Advice to anyone taking narcotics - do NOT mix with alcohol - you'll overdose, don't take more than directions - you'll just build tolerance & they won't work. If your medicine stops working as mine did, don't take more, tell your Doc, a different combination can change everything!"

9 / 10
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78 Report
  • Sharp...
  • Taken for 2 to 5 years
  • October 24, 2019

"When I was 28 I was in Iraq (2010) as a gunner for our Sgt Major and Colonel. We was on a mission and 3 IED’s (improvised explosive device) went and flipped our truck. My strap broke when I was in the gunners hatch but long story short I broke my back and my right leg. I was given the MBlock 15mg pills and it worked but I switched doctors and they prescribed me the RP 10/325. I am a strong person and can take a lot of pain but when it gets unbearable I do expect for the medicine to work. So I understand what all you are going through when you take the RP 10/325 and it doesn’t work. I will pray for everyone that’s having any kind of pain and trust me things will get better. We can’t expect them to understand our pain when they don’t have to go through it. Try the 15mg Mblock or the RP 20"

1 / 10
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  • Cruzer
  • May 22, 2020

"I’ve been a long time user of Percocet for neck, thoracic and limb as t pain. In addition I’ve had 4 surgeries on left knee and reconstruction of right. Initially I was prescribed Mallink 5/325 Percocet for pain, which worked well. My provider recently changed manufacturers of Percocet, which doesn’t appear to be as effective. My question is what gives. Is it less opiate or the process of manufacturing"

4 / 10
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  • Anonymous
  • September 6, 2012

Percocet 10/325 (acetaminophen / oxycodone) "I suffer from severe neuropathy from my diabetes and have been on several pain medicines in the past. The last one was Lortab 10/500mg and did not take away all my pain. I was hurting after 3 hours of taking it. I was put on Percocet 10/325 by my doctor and I could not believe what a difference it has made in my life. I feel like I have my quality of life back. I can get around better and do not stay in bed most of the day from the pain. I was so depressed from being in so much pain. Now I am up and moving around better than I have in 2 years. I thank God my doctor has taken the time to listen to me and finally put me on something that works. He left me on the Lortab as well for breakthrough pain medicine but I have not had to use it."

10 / 10
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79 Report
  • Kipki...
  • October 24, 2016

Percocet (acetaminophen / oxycodone) "After breaking my back and being rated disabled because of the permeant nerve damage, and constant pain this is the only prescription that helps me lead as close to a normal life as possible. I have tried several other options and none have been effective. I was told to get in the best shape of my life and stay like that, so I am, but that just keeps me at a certain level of comfort. I hate being stereotyped into a group of users, I am not a user. When I have gone several weeks without it, day to day tasks are incredibly difficult. Being a college student, having my prescription is the only way I can sit and study. It allows me to put the pain in the back of everything and concentrate on studying. I do make sure i am not addicted."

10 / 10
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57 Report
  • Swede
  • Taken for 1 to 2 years
  • October 5, 2020

"I initially started with Watson brand then my pharmacy changed to Mallinkrodt generic after both of those companies went by the wayside they started carrying only Rhodes. The Watson brand work very well. The Mallinkrodt brand well not as good as the Watson was still quite good at reducing pain. The rhodes brand I have been on for the last year and a 1/2 has left me feeling really draggy and almost like moving in quicksand a lot of the time and its effect on pain is substantially less then any of the other generics of this medication I have taken if you can get another generic brand or the actual brand you would be way better off."

2 / 10
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33 Report
  • Dean
  • April 17, 2014

Xartemis XR (acetaminophen / oxycodone) "Today was my first dose around noon, then the second dose around 5:30 pm. I have to confess, I was a bit nervous about taking this med. I get panic attacks when trying new meds, especially because I could not find any patient reviews anywhere on the internet - I guess I am the first. Also, the large size and bright blue color did intimidate me. I have chronic pain from fibromyalgia, herniated discs in my neck and back, and now battling kidney stones. So far, I have had no pain today and also have more energy than I have had in the last 6 months. Before, I was on Percocet 10mg and Mscontin 15mg, but I had to change my PM doc, and she took my meds away and gave me Xartemis instead. If the rest of my days go as this one, I think I will stay on this medication."

8 / 10
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68 Report
  • great...
  • Taken for less than 1 month
  • February 12, 2013

Percocet (acetaminophen / oxycodone) "I'm 51 years old and have been dealing with chronic pain last 20 years. Put on MsContin 60mg 3 times day, it's long lasting but pain sill comes through. Dr. added 10/325 Percocet for break through pain. Made my life liveable. Give it a 10."

9 / 10
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72 Report
  • Jaywi...
  • January 17, 2015

Percocet 10/325 (acetaminophen / oxycodone) "I have Multiple Sclerosis and I have chronic back and legs pain along with headaches and I have tried about everything else in the book and nothing seems to work except this. Take 1, 15, 20 minutes later it kicks in and pain is gone for a while (about 5 hours)."

10 / 10
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  • Bee
  • Taken for 1 to 6 months
  • December 29, 2019

"I have been taking generic percocet for years off and on for chronic pain. I did have Camber brand acetaminophen with oxycodone before and had constant sweating. I now have finished 60 over 4 months of Mallinckrodt and had constant stomach pain and nausea when taken. The pain medication has a shorter effect to keep the pain away. What is in this Mallinckrodt Brand of acetaminophen with oxycodone. I cannot take it anymore? I have mentioned this to my doctor and the pharmacist to no avail."

3 / 10
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  • Chron...
  • Taken for 5 to 10 years
  • April 16, 2019

"Same experience as others filling Percocet at Walgreens . Sick like a dog and didn’t take care of my chronic pain. Had to switch to Alvogen brand and and I’m on the third month of severe diarrhea. I’ve been worried to death that I have cancer or something. I am convinced that this started when I was switched to an inferior brand. I suspect that the CDC has forced pharmacies to supply us with a drug that will cause us in time to not want to take it anymore. Please ! Fix this injustice to legitimate pain patients. This is truly torture and someone needs to investigate please. Both pharmacies in my small town is in on this effort to curb our use. On a good note , the CDC and doctors now can’t just drop a patient cold turkey or drop the dose too much at a time. It’s considered inhumane. Now , what about us, please give us back our correct medication strength."

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  • Anonymous
  • April 5, 2021

"RP10/325 white oxycodone, made by Rhodes pharm. are highly ineffective for the treatment of pain, this medication should be removed off the market. It causes stomach problems, irritability and sleepiness. It really has only added to and aggravated my pain rather than helping to manage it. I don't know if it is the hydrochloride or what but this the worst pain medication ever and I will be taking mostly motrin this month and avoiding being active in an effort to manage my pain until my pharmacy gets my more regular brand of prescribed pain medications and will only take one of these horrible ineffective pills at bedtime to ensure I dont suffer with opioid withdrawals so that I can go to work. This is all that this medication is good for, is simply to ensure that you don't get withdrawal symptoms until next month when I can get a decent brand of medication again."

1 / 10
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28 Report
  • Mike...
  • Taken for 1 to 6 months
  • August 9, 2023

Percocet 10/325 (acetaminophen / oxycodone) "As a sufferer of chronic pain for 15 years, I finally feel better. Recently, I blew out my shoulder and have severe neck issues which unfortunately I need surgery for both. Don't know if it's just me but Mallinckrodt pills with the imprint M 523 have finally been the medication that has and is saving me from a deep dark depression. Thank God there are the means to do this now with insurance benefits from work because had this been 9 months ago, I'd be totally screwed. This is on top of all the chronic pain I've suffered for so long. Went through it the past 6 or 7 years without medication needed. These 2 newer injuries are absolutely kicking my ass. These pills in particular have been godsent so much so that my pharmacist promised that these pills that I'm speaking of, M 523, would be what they give me from here on out. Strongly recommend these for sufferers out there."

10 / 10
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  • yaya
  • Taken for 2 to 5 years
  • September 22, 2012

Percocet 10/325 (acetaminophen / oxycodone) "I have had 3 back surgeries by the time I was 25 years old. I have degenerative disc condition and on top of that, I was involved in an accident at work which resulted in a herniated disc. I went through a discectomy, a spinal fusion, and a correction surgery. Needless to say, I have A LOT of hardware in my back! Percocet was wonderful. It made my recovery bearable and living a somewhat normal life. Unfortunately, I'd been on it for 3 years and then my doctor cut me off cold turkey and told me to take Tylenol extra strength. The withdrawals are awful and I'm still living in awful pain, but I had 3 years with mild to no pain with Percocet!"

8 / 10
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72 Report
  • Dolly
  • Taken for less than 1 month
  • January 17, 2019

"CAMBER Distributors are made out of the US and local pharmacies are using them - they are equivalent to a sugar pill. I cannot even believe my pharmacy switch to them. I am not accepting foreign knock off medication I am not even sure if there is any oxycodone in this at all!"

1 / 10
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40 Report
  • Migra...
  • February 4, 2013

Percocet (acetaminophen / oxycodone) "I have had migraines for over 25 yrs as well as fibromyalgia. I take Percocet 5-325 which has been the only thing that keeps me a person not just hiding in my room from the pain but I have started to notice that I have needed to take 2 pills ever 4-6 hrs instead of just one. But this pill has been a life saver."

9 / 10
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69 Report
  • Rx Man
  • March 2, 2019

"Ok , here’s the real deal -The FDA allows up to a 20% variance between the Brand vs Generic -medicine , As far as the Absorbtion Rate . Totally ridiculous! The FDA should only allow up to a 2% variance . The Active ingredients have to be 100% the Exact same. However, the Inactive ingredients Do Not. Think @ it- The company manufacturing the Brand medicine has the inactive ingredients in the compound for a reason ( maybe the inactive ingredients are directly affecting the Absorption of the Active ingredient/medicine ). Furthermore, Once the company manufacturing the first generic loses it’s right to be the only one making the generic -Additional manufacturers that make this Generic ,Only have to compare it’s Generic Version to the First Generic. Therefore, the 2nd, 3rd, etc.,Generic version to come out, can be Up To 20% Less than the First Generic. Therefore ,You could be getting a Generic that’s only 60% of what the Brand medicine is ,As far as the Rate of Absorbtion ."

7 / 10
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  • Anonymous
  • September 2, 2023

Endocet (acetaminophen / oxycodone) "Endocet 7.5. I have a severe spinal cord injury. A large, prominent hemangioma that is compressed in T6 with disks bulging. I also have cervical radiculopathy c6 c7, compressed with severe foraminal narrowing. My lumbar is degenerating as well. This medication helps. I suffered for years in Humboldt County, California. Doctors refused an MRI for 12 years. Now I have severe arthritis as well as osteophytes. I take 4 pills a day and I am grateful. After 12 years in Humboldt County, California, with zero help, I moved to Indiana where they gave me an MRI immediately and were appalled by the care I received in California. I have had cortisone injections which caused me to go blind. After 6 surgeries, I can now see but not after dark. I don't have mobility anymore. I am so grateful to have something more than Tylenol. Acupuncture, chiropractic treatments, body manipulations, homeopathic doctors, and physical therapy did not help. I spent thousands of dollars. This inexpensive pill is everything to me now."

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  • PJano
  • August 17, 2018

"I've used Actavis, Anmeal, Mallinchrodt, Camber. The best has been Actavis, (used to be Watson). Mallinchrodt is a close #2, but both of these actually provide relief for me. Stay away from Anmeal and Camber (garbage). The pharmacy stopped carrying Actavis, and only carry Camber now. After 2 months of little to no relief I requested that they order Mallinchrodt as they won't order Actavis anymore but will order Mallinchrodt. If you're a long term customer they will do it for you. As others have said if you leave the store with a useless brand you're stuck for 30 days. FDA and media always over react and intimidate docs. Your Doc doesn't want to have to explain why he or she wrote you 2 different scripts. If W refuses to order something different you need to tell your Doc that you will be using a different pharmacy moving forward. Docs don't care where you buy the RX they just don't want you to be pharm shopping. Always be honest with your Doc about this kind of stuff, they know about the bad generics and will be merciful with you if you're honest with them."

9 / 10
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41 Report
  • Scott...
  • Taken for less than 1 month
  • August 20, 2016

Percocet (acetaminophen / oxycodone) "short-term OK for pain would not want to take long term I am a cancer survivor and my most of my body hurts all the time I have yet to find a pain medicine that is safe and effective and non-addictive that helps with this side effect of massive amounts of chemo it's been 6 years and I've been living in pain everyday I understand why Colorado and California legalize marijuana I don't smoke pot I used to. but if someone comes over with a joint I may take a hit and I will say that marijuana does help the pain I would not want to use as a recreational drug but it does help the pain better than any opiate that I've ever taken"

7 / 10
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  • NayNay
  • Taken for less than 1 month
  • July 10, 2019

Percocet 10/325 (acetaminophen / oxycodone) "My pharmacy changed to this manufacturer. Wow. What a difference in strength. I thought it was me, too, till I read the reviews! Now what do I do. I’m stuck with 30 days of meds. More expensive, too."

1 / 10
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36 Report
  • FDA...
  • Taken for 10 years or more
  • October 29, 2017

Percocet 10/325 (acetaminophen / oxycodone) "After being on for 10 years or more I find now even my pain management doctor as to cut my meds thanks to the new FDA guide lines ,the FDA is so worried about overdose on opoiods because other people has abused them but have forgot about those who do need pain meds. I've heard it all in the last three months from my doctor I even had to change 3 of my other medications because I can't be on them if I am taking pain meds To me ever since that most states made Marijuana legal the FDA as turned to people taking pain meds guess they can't control the other un legal stuff out their so they try and put the focus on pain meds even though the FDA says that we would not take pain meds away from Those who need it .. guess what FDA you have !!!! get your facts FDA"

8 / 10
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45 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.