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Acetaminophen / hydrocodone for Back Pain User Reviews (Page 4)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 5.7 out of 10 from a total of 385 reviews for the treatment of Back Pain. 47% of reviewers reported a positive experience, while 39% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • Annoyed
  • Taken for 10 years or more
  • May 8, 2019

"Refilled my monthly pain meds, and since then I have had a pain increase as they have switched to the Mallinckrodt brand of acetaminophen with hydrocodone. So much so, it’s causing me to not be able to sleep through the night. I have found the best brands of acetaminophen with hydrocodone are Qualitest, Watson, and Par (not sure on the spelling of Par) to work the best for me personally. I have been on the same dosage for 11 years+. If it’s the exact same drug and the same amount of medication, why are my pain symptoms so much higher, along with others I’m seeing, if everything’s the same? And who’s checking these medicines? Does the FDA do spot quality tests to see if the active ingredients are the right strength?"

1 / 10
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  • Vcr...
  • Taken for 10 years or more
  • March 9, 2020

"Just got my script of generic Norco (acetaminophen & hydrocodone) made by Tris Pharmacy. Has no pain relief properties whatsoever. I used to get the ones that said IP110 (Amneal Pharmaceuticals). At least they worked. Am gonna just throw these away."

1 / 10
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49 Report
  • Broken...
  • Taken for less than 1 month
  • February 27, 2020

"My medicine was recalled back to Rhodes and Parma Pharmaceuticals for testing. I am having all the above complaints: something's changed: heart racing, no relief, valve problems, lethargic, zombie, headaches. It’s like the chain on medicine that doesn’t work. Will relay updates later. Thank you."

2 / 10
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49 Report
  • Cindy
  • Taken for 2 to 5 years
  • August 12, 2019

"I noticed my pills were a different shape than normal but assumed they would be the same. NOT!!! Aurobindo brand of acetaminophen and hydrocodone do not work!! I had been happy with SUN Pharmaceuticals brand for about 3 years. I don't know why CVS started giving me Aurobindo brand but I will not be accepting them again. They are absolutely useless. I feel so taken advantage of and am getting no pain relief for my back issues, fibromyalgia, ankylosing spondylitis, etc. How can this happen?? I am so angry."

1 / 10
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53 Report
  • Dudeman
  • Taken for 10 years or more
  • December 19, 2018

"I have had four past back surgeries, including disc fusions. As a long-time, 20 years on and off, very intelligent opioid user, I know what works for me and what does not. To say all generics are the same is totally incorrect. To make a long story short, I have taken every generic Norco known to man. A great pharmacist who actually cares about my chronic pain and generic struggle, who works for Walgreens, has recently begun ordering the yellow Qualitest/Par brand for me. They are so much better than any other brand on the market. As close to the old Watson brand as you can get since the crackdown. All pharmacies, as well as the large ones, can order just about any brand. Just keep moving up the chain when they tell you they can only get the white Narcos and you will find a pharmacist that actually understands and cares about your pain control."

5 / 10
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58 Report

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  • Patsy
  • Taken for 10 years or more
  • December 6, 2019

"I picked up generic Norco refill today (acetaminophen / hydrocodone). Rite Aid switched to T 259, which is made by Cambra. Cambra started generic Norco early this year. I was taking Mallinckrodt, which worked for me. T 259 Cambra acetaminophen with hydrocodone is not working for me. Anyone else taking this brand?"

3 / 10
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50 Report
  • Useless
  • Taken for 1 to 6 months
  • July 10, 2022

Norco (acetaminophen / hydrocodone) "I am taking Norco for back pain and severe bilateral hip pain while waiting for hip replacements. First, I was on 5/325, then my doctor increased it to 7.5/325. If it slightly relieves the pain, I am lucky. About 75% of the time, it does absolutely nothing."

1 / 10
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  • James
  • May 17, 2019

"Mallinckrodt brand of acetaminophen with hydrocodone (generic Norco) does not work. All major pharmacies are switching over to this brand. I have been taking this medication for the past several years and never had a problem until recently. I shared with my pharmacist the reactions to this manufacturer, and she noted it in my chart. Here I am a few months later picking up my RX. I couldn’t remember the Mallinckrodt brand name that caused the issues prior, nor did I think I needed to tell the pharmacy every single time seeing as they had I could not take and my reaction in my notes. After the first dose, again... sick as a dog. I called CVS to ask them the manufacturer I was unable to take, and sure enough, it was the one they gave me, MALLINKRODT! They apologized and said they have no control over what they get and there’s nothing they could do for me. This is just flat out wrong and what am I supposed to do now? I don’t see how they are able to get away with this. I am reporting them to the FDA, in which I have a feeling is a part of this as well!"

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  • SueW
  • Taken for 10 years or more
  • May 9, 2018

Vicodin (acetaminophen / hydrocodone) "I had been on Vicodin off and on for the last twelve years until recently. My doctor will no longer prescribe this for me because of all the addiction news that is going on with the government. I have had two spinal fusions in the past fifteen years and never abused the drug nor had any addiction problems. It is the only medicine that helped my pain. I have not found anything to replace it. I now take four Motrin at a time, along with a herbal supplement called Kratom. This lessens the pain somewhat, but I am still in severe pain at times. I had no noticeable side effects from the Vicodin."

10 / 10
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  • RonMe...
  • Taken for 2 to 5 years
  • June 10, 2019

"I got the generic acetaminophen with hydrocodone with the imprint M367 (Mallinckrodt Pharmaceuticals). These have maybe the equivalent of 1 mg hydrocodone, if even that. Been taking other generics and name brands for years, 10/325's to 10/600's, etc. Immediately began suffering withdrawal once I went on to the Mallinckrodt brand. First thought was the pharmacy had obtained some fake 'pressed' pills. But in reading others' comments, what is happening is so obvious. The company/resident chemist is not mixing in hydrocodone into these particular generic brand Norco pills. Do not waste your money as they are as good as a sugar pill. The company should be sued and put out of business immediately. This is a flat-out conspiracy. The FDA needs to investigate. Make sure if this happens to you, please send in a complaint."

1 / 10
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52 Report
  • Gmato
  • Taken for 10 years or more
  • May 22, 2019

"Have had chronic pain since the 90s, and for years I took Watson brand of acetaminophen with hydrocodone and was and still would be fine with it if I could find it. Also took Mallinckrodt brand, and it was fine up until recently, sometime in the last 4-6 months. They have changed the formula, the pill is smaller, and it seems to have a sleeping agent instead of a pain reliever. Never have these pills made me tired before, in fact, just the opposite. By controlling pain, I could go about my busy day with confidence and ease. Now this company has ruined a perfectly good chronic pain reliever, and I spend more time in tears due to pain. If anyone can suggest how I can find Watson, I would be so thankful."

2 / 10
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52 Report
  • Rina
  • Taken for 10 years or more
  • March 28, 2019

"I have severe back issues, DDD (Degenerative Disc Disease), arthritis, and was in a car accident. I have taken Norco, 10/325 with Watson on it, for over 10 years. I took 2 a day and was great, I could work all day, sleep great, I was able to be very productive in my life and career. This brand is horrible, does not touch the pain, makes me itch, nauseated, and bloated. I'm less functional and really irritated. I have pain the majority of every day. Here where I live, almost everywhere has this brand. I wish they had the Activist white Watson. I found an old one and 'WOW,' I could function, and that proved it is in fact the other brand is like a placebo... I'd like to report this, I will research how."

3 / 10
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53 Report
  • Bjano
  • Taken for less than 1 month
  • August 30, 2020

"I've taken this drug, generic for Norco (acetaminophen/hydrocodone), for many years, and I don't know why they have them, they are not the same drug. Throw them in the trash. I wanted to get them tested to see what was in them, but they said because I was on Medicare, I could not. They signed a contract. They did not want to be liable. Be careful, be aware. This is not what they say it is."

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  • retired
  • March 2, 2019

"No longer getting pain relief. I'm 70 years old, no problems controlling my pain until recent drug company changes. My pain level is much higher with the same dosage. Have 2 degenerative discs in the upper and lower back, fractured vertebrae mid-back inoperable due to osteoporosis. I was taking 10-325 twice daily for 6 years, that worked well with periodic spinal injections. I was functional with minimal discomfort. Now my pain level is through the roof on the same dosage. PCP had to add Nexium and probiotic because I'm having stomach problems with this new formula. Expected to be made comfortable in my dotage and was managing that very well. Now I'm in excruciating pain again and have additional problems to boot. Seniors need the government to step in, IMHO."

2 / 10
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53 Report
  • Sam
  • Taken for 10 years or more
  • September 25, 2020

Lortab (acetaminophen / hydrocodone) "I've been taking Lortab for over 30 years. It's not helping my pain at all now. I've had 7 back surgeries, which helped but not for long. I need advice on what else I can take. I've got a pain management. I need some help."

2 / 10
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  • Chris...
  • September 6, 2019

"Wow, I am in shock. I searched for this a year ago, and I couldn't find any reviews about bad medication (dud brands of acetaminophen with hydrocodone), and I felt alone. I do not feel alone anymore. I've taken pain medication for multiple health issues and injuries for about 12 years. All of a sudden, things changed, manufacturers changed, and the Norco whatever brand the pharmacy switched to and gave me didn't work and gave me horrible side effects. I specifically only liked taking Watson acetaminophen/hydrocodone because it was the only brand that helped with pain, lasted longer, and barely any side effects and did not put me to sleep. Then, all of a sudden, Walgreens changed to Tris brand. I literally felt like I was dying or I was going to have a seizure."

2 / 10
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49 Report
  • Mcano
  • December 29, 2019

"I'm on the horrible generic Mallinckrodt brand of acetaminophen with hydrocodone. It is absolute garbage, doesn't work for the pain, gives me a fuzzy head, sick feeling. I don't even think there's any hydrocodone in it. In the trash it goes, and in pain I stay."

1 / 10
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45 Report
  • TJJ
  • Taken for 2 to 5 years
  • October 7, 2018

"I agree with everyone! There is ABSOLUTELY no way they are putting the whole narcotic amount they are supposed to have in these useless M367 pills (Mallinckrodt Pharmaceuticals brand). Someone with some clout needs to turn this company in to the FDA. I have been on the Watson brand for 4 years, for a myriad of health problems. These meds made me feel dizzy, sick to my stomach, and DO NOT HELP with the pain at all. The Watsons worked, M367 DO NOT. Maybe the Feds are in on it to make us suffer, or maybe the company is scheming narcotic off the books. All I know is these Mallinckrodt Pharmaceuticals M367 DON'T WORK!"

1 / 10
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  • NORCO...
  • Taken for 10 years or more
  • September 18, 2013

Norco (acetaminophen / hydrocodone) "Two major lower back surgeries, was in major pain! A doctor told me about Norco, and I tried Norco with great success for 10 years. I realize that is a long time to take this! I now have a pain management specialist doctor and have tried other products to stop the pain. I have always come back to Norco 10-325 because it did the job for me. Norco 10-325 gave me my life back. My pain is under control with this product."

9 / 10
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83 Report
  • Ronnie
  • Taken for 2 to 5 years
  • January 12, 2020

"I am glad I found this. I was starting to think it was all in my head. My Rite Aid recently switched my hydrocodone to the yellow generic Camber ones. These give me an upset stomach and really bad insomnia. When I take them, I feel like I'm hyped up, and yet they don't work as well. I called the pharmacist, and he told me Rite Aid has switched to this manufacturer for now. They act so weird about this medicine that I hate to transfer pharmacies for just that, but I feel that the pills are actually worthless, it's like taking a couple of Tylenol and getting this upset stomach."

3 / 10
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  • ChrisT
  • Taken for 10 years or more
  • March 1, 2019

Norco (acetaminophen / hydrocodone) "I have had fibromyalgia and RA, as well as depression, anxiety, low vitamin D levels, migraines, and chronic fatigue syndrome. My doctor asked if I wanted 10/325 Norco or 5 mg Percocet. The Norco worked better and was less sedating and itchy. I know from the dentist I need 10-20 mg Percocet. Norco keeps me awake, functioning (out of bed, I’m disabled), but lets me get up and move around, also less addictive. I also take Cymbalta, Topamax, Xanax, Lunesta, Adderall, Norco, Soma, etc."

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50 Report
  • Anonymous
  • Taken for 10 years or more
  • June 23, 2019

"I have been using 'Watson' generic name for hydrocodone / acetaminophen 10/325, also formally 10/500 Watson / a blue pill as opposed to the white variety. Now my local pharmacy uses Mallinckrodt, which does not help my back at the prescribed dosage. Can anyone help?"

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  • Ladybug
  • June 9, 2019

"I have spondylolisthesis, stenosis, scoliosis, arthritis, a fracture, and also a cracked tailbone. I am approaching 60 years old, and I've worked all my life until I became disabled and could no longer due to my serious back conditions. I had to work with severe pain because I refused to take pain meds before I was classified as disabled. Due to this so-called 'opioid epidemic,' my doctor only prescribes generic Norco 10/325 mg (acetaminophen and hydrocodone) and only 3 per day. All I ever get is this Mallinckrodt brand, and for a year solid I swear it had NO pain medicine in it. IF it had any, it was no more than 2 mg. OK, then suddenly about 5 months ago they started to feel full strength again and worked great for my pain, not taking it all away at all, but I felt better. I just got my new month's prescription, and it's BACK to the placebo ones again, the pure JUNK, it does NOTHING for my pain. You definitely KNOW when it's garbage because it doesn't touch my pain, and it just feels like it's all Tylenol or filler."

2 / 10
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  • KKran...
  • Taken for 1 to 2 years
  • August 13, 2018

Norco (acetaminophen / hydrocodone) "I’ve been taking Norco for about two years. It’s really the only thing that helps my pain. I usually get my script filled at CVS, and lately, I’ve noticed the generic they use is pretty worthless. Takes sometimes double the pills to get just a little pain relief. Recently switched to the M367 generic (Mallinckrodt Pharmaceuticals) at Walgreens, and wow, what a difference. One pill lasts me almost an entire workday, whereas the other generic was requiring two to three just to get partial relief. Never really thought there was much difference in generics, but I guess there is!"

8 / 10
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  • glaydes
  • Taken for 2 to 5 years
  • February 13, 2020

"The generic manufacturer of acetaminophen/hydrocodone is making a lower dose of the hydrocodone and causing side effects I've never had before. I now get headaches (I have Cushing's syndrome and any headache is scary because I have a tumor on my pituitary gland). I am experiencing lower pain control and nausea. This medication does not work well for my conditions. This includes diabetic neuropathy, degenerative disc, sciatica nerve pain, and spinal stenosis. This medication does not relieve the pain like hydrocodone I have been prescribed before."

1 / 10
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41 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.