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Acetaminophen / hydrocodone for Back Pain User Reviews (Page 2)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 5.7 out of 10 from a total of 385 reviews for the treatment of Back Pain. 47% of reviewers reported a positive experience, while 39% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • JPano
  • September 12, 2020

Norco (acetaminophen / hydrocodone) "For years, I took brand Norco (acetaminophen/hydrocodone) when it was manufactured by Watson. When the drug went off-patent, many companies jumped in to manufacture generic versions of the drug. At one time, Watson was manufacturing a generic, which was great since it was exactly the same as the brand, but Watson was bought out, and it's impossible to know (except through trial and error) whether the purchaser is using the Watson 'recipe.' As for generics, acetaminophen with hydrocodone, for me, the generic Norco manufactured by Aurobindo has been excellent, as has that manufactured by Mallinckrodt and Rhodes. I have also been able to take the generic manufactured by Tris with what is usually adequate pain relief (but not as good as Aurobindo, Mallinckrodt, or Rhodes). The generic that I absolutely cannot take is Amneal - it's like not taking anything at all. I'm not sure why, as all of these drugs should have the same amount of opiate in them, but I might as well not fill the prescription if the generic is Amneal."

9 / 10
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106 Report
  • rocko
  • Taken for 2 to 5 years
  • December 13, 2014

Norco (acetaminophen / hydrocodone) "I did 6 years of active duty with the army as an infantry soldier. I've been in the Iraq war in 2004 and the war in Afghanistan in 2006. During combat, I've been in 6 IED explosions. A gunshot through my left shin, nerve damage to my whole right hand. Compressed 3 discs and shattered 1 in my lower back. I have Traumatic brain injury which causes horrible migraines. I've been on everything since 2007...OxyContin 80mg, 30mg Roxys, 125mg fentanyl patches, morphine 60mgs, etc. Currently, I'm on 10/325 Norco 6 times a day. I've grown dependent and tolerant to opiates. But Norco is by far the best medicine to make my chronic pain tolerable. And the side effects are close to none. I highly recommend this for chronic pain."

10 / 10
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200 Report
  • BoraB...
  • February 27, 2019

"The real truth! They're messing with your pain pills, America! Pain pills are completely different than what they used to be. They're changing them to prevent abuse. In turn, now they're not working. Every brand is doing it. This is why you can't find relief anywhere. They're punishing you people with real pain issues because of abusers' actions. Which should be completely illegal. I guarantee anybody with more power than me could have these things inspected, and probably could win in a court setting. Someone with more power than me needs to stand up for us people with real pain issues. Facts!"

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129 Report
  • G037
  • Taken for less than 1 month
  • November 25, 2022

Lortab (acetaminophen / hydrocodone) "I changed pharmacies from Walgreens to CVS. I had my prescription filled and it’s a different brand G037 acetaminophen/hydrocodone. This brand is making me sick. I was taking M367 acetaminophen/hydrocodone and it worked well, just enough to get me through the day. They need to fix this because people will want to move up to something stronger. Something definitely is wrong with medicine."

1 / 10
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53 Report
  • Krissy
  • June 13, 2019

Norco (acetaminophen / hydrocodone) "I was injured years ago badly. When I fell, it worsened & had surgery. My pain is severe & classified as intractable. PT helps but my back pain persists. I tried Percocet, morphine & Hysingla, but nothing touched the pain. It was as if I hadn’t taken anything! I was taking too many Advil a day, which helped, but the doctor said that’s very dangerous. I gave up & she suggested 1 last medication, Norco. I was skeptical & gave in to the pain but took just one pill & after 1 hour, I had no pain for hours! I’ve had excruciating pain for so long, and it honestly feels strange not to have it a few hours a day now. Another plus is NO SIDE EFFECTS like others (dizziness, out of it feeling (I guess euphoria which I hate), no constipation) and it just works! Husband sees a difference in my outlook and how I’m walking better. There’s a need for a 2nd pill midday when the morning one wears off, then some pain at night. But I’m okay with pain at night because I’m just resting. I’m finally getting my life back. I really just can’t believe it!!!!"

9 / 10
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111 Report

Are you taking this medicine?

  • Jones
  • Taken for 5 to 10 years
  • June 21, 2019

"Me Arthritis, torn L3, neck nerve damage, sciatica, bullet in leg lodged between the nerve/bone. Recently had spinal fusion surgery, titanium rods inserted in spine. Taking Percocet 10/325 and Norco 10/325 for breakthrough pain. The MANUFACTURER DOES MATTER. I made it CLEAR to the pharmacist I will only take Endocet MANUFACTURER with the Percocet and EYWA MANUFACTURER for the Norco. I won't leave the pharmacy until I check. Comments about manufacturers, you are NOT crazy or imagining things. These foreign discounted suppliers are causing problems for hard-working, tax-paying TRUE PAIN SUFFERERS like us with their knockoff brands. We ALL need to write to the FDA and get a petition going. Not to mention the addicts who want to shoot and snort these pills, then again WE SUFFER! I have a great doctor & pharmacist, thank God, who knows MY PAIN IS REAL and my medication lasts me from one appointment to the next, random urine tests prove it. To my family of pain sufferers, may we ALL have long-lasting relief very soon! MRS. JONES"

7 / 10
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108 Report
  • Dave
  • Taken for 2 to 5 years
  • January 4, 2019

Norco (acetaminophen / hydrocodone) "I switched from Rite Aid and the useless Mallinckrodt (Malincrap) brand to an independent pharmacy that sells the yellow 3601 Norco in October. I couldn't believe it, but I only need 2 a day to control my pain. The next 3 months, the same yellow Norco had decreased in pain relief to the point that my most recent script was total garbage. Same pills but different shipment. Complained to the pharmacy and now I'm filing a complaint with the FDA. People must file written complaints for the FDA to investigate. PHAR P, that's the brand."

2 / 10
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113 Report
  • Babyg...
  • Taken for 5 to 10 years
  • July 29, 2018

Norco (acetaminophen / hydrocodone) "I have been taking Norco for a while, and the manufacturer was Actavis. They really didn't help that much. Well, I just got another prescription filled, and Walgreens changed the manufacturer again to Mallinckrodt, and they do nothing at all but give me pains in my stomach and a slight headache. I wish these manufacturers would stop playing around with the ingredients. We are in pain and need something effective for pain, not the ineffective ones we are getting now."

1 / 10
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117 Report
  • Tammy
  • Taken for 6 months to 1 year
  • October 20, 2022

Norco (acetaminophen / hydrocodone) "The generic Norco Mallinckrodt m367 for 8 months and never really helped pain. Even at the start. But in years past I have had NORCO 10/325 after 3 different surgeries and I can say that they worked well for pain relief. Not these Mallinckrodt . Seems the formula is change to satisfy the Gov. desires. Even some pharmacist agree but won't say publicly for fear of bucking the system. Todays generics appear to be inferior."

2 / 10
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43 Report
  • Lolly
  • Taken for 2 to 5 years
  • July 14, 2019

"M367 is junk... I called the FDA and I need to fill out a formal complaint... I’m trying to get the yellow Par Pharm or Watson brands. They are messing with our meds and we need to stand up and fight. I’m miserable on these. Please, everyone who is getting this knockoff M367 Mallinckrodt Pharmaceuticals brand, report to the FDA. I’m suffering with fibromyalgia and multiple back issues and arthritis. If FDA employees had pain, we wouldn’t be having this issue."

1 / 10
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88 Report
  • Patty...
  • March 31, 2023

Norco (acetaminophen / hydrocodone) "I have had surgery to replace my fractured C5 vertebrae with bone harvested from my hip; I have had back surgery to replace a disk; and I have had spinal fusion surgery. I now have arthritis in my hand and shoulder. I have taken Norco 10s for the pain over the years and have found them to be highly effective with no side effects or withdrawal symptoms. My doctor prescribed Norco 10 for my arthritis but the only medication the pharmacies in my area carry are manufactured by Mallinckrodt, and they are terrible! They don't reduce the pain AT ALL, but they're GREAT at making me nauseous. If your doctor prescribes generic Norco 10s by manufacturer Mallinckrodt, don't bother - the product is worthless."

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32 Report
  • ezzboat
  • Taken for 10 years or more
  • May 27, 2015

Norco (acetaminophen / hydrocodone) "I'm taking Norco 10/325 for over ten years on and off. I'm over sixty-five. I've recently come to the reality that this wonder drug has lowered my back pain, diabetes sugar, depression, and neuropathy pain. I've been told I have reverse side effects from this medication than the average patients the doctor attends to. Everyone else says, 'Oh, you're hooked on pain meds', so what. If they help all of these problems I have and have no bad side effects I can't live with. The best to this drug."

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129 Report
  • Karrie
  • January 7, 2020

"Do not accept these rubbish brands! You don't have to go to CVS, Walgreens, or Walmart. Just find an independent pharmacy as I have done, and they were kind enough to order me the Cara brand, and I said I would cover out of pocket if my insurance didn't cover it. Do not accept useless pain meds! We are human beings, and it's not our fault about the opioid crisis!"

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76 Report
  • KmRie
  • February 21, 2020

"Over the past six months, I can't find any other brand of acetaminophen and hydrocodone but these new pills by Mallinckrodt, and similar. Definitely, this is the government and big pharma trying to curb the opioid epidemic without telling anyone. Who can afford a lawyer big enough to dig into this? Cardinal Health is now a 50-50 partner with CVS, and Cardinal regulates what drugs get distributed to all pharmacies. I heard this from two pharmacists directly. They took away their right to choose order-specific manufacturers. Imagine the money they're making by not even putting the active ingredient in these pills and selling them for the same price. They know that you're going to be treated as if you're a drug addict if you say anything. The only recourse you do have is to complain through the proper channels. That's about like saying you want your tax rate lowered for your income bracket! Unfortunately, people with true chronic pain issues are suffering because they don't fix the issue of addiction."

3 / 10
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74 Report
  • Angry...
  • Taken for 5 to 10 years
  • September 6, 2020

"I’ve had multiple back surgeries, fusions with hardware a few months back. The past 2 months CVS changed to Lupin acetaminophen/hydrocodone 10mg. I’ve had no relief from this medication and went through withdrawals for a couple days. I actually thought I had COVID but tested negative. I found hydrocodone in my medicine cabinet from my last surgery that I tried and had solid pain relief for almost 6 hours. Whatever these manufacturers are putting on the market is complete garbage. I’m going back to my doctor Tuesday to see if she can switch me to oxycodone or change to a brand name."

1 / 10
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67 Report
  • green...
  • Taken for 10 years or more
  • April 6, 2019

"Acetaminophen with hydrocodone generic quality issues. I had thought having to switch back and forth (thru CVS filling prescription) of Qualitest generic, which is good, and the Mallinckrodt generic, which I had thought was the worst. Now I am in pain and no way to shop around, I have had to accept this. Now I have gotten to experience Aurobindo brand of Acetaminophen with hydrocodone, what a joke, and now 3 weeks in, depression has settled in. What in the world do they put in this stuff? At 72, I still work but if this is the brand I will be getting, then I have to admit I may have to quit work. There is a burning pain in the tissues that settles in by the end of the night, and the depression is getting more overwhelming, it seems. I just can't see why us long-term pain patients have to suffer. I don't care what problem they are having with abusers, it doesn't delete me nor my pain."

1 / 10
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84 Report
  • Jantz...
  • Taken for 1 to 2 years
  • December 18, 2020

"I am so done with this generic hydrocodone. It does absolutely nothing for my pain and I don't understand how this medicine is even allowed on the market. There is no way in Hattiesburg there's more than 1 mg of hydrocodone in the 10 mg tablets. This stuff just makes me sick-ish and sleepy. Years ago it always worked, heck a half of one worked, now 2 won't even work. There is not one generic on the market today that is worth taking. If your doctor prescribes this for your pain you're pretty much going to suffer in pain like me and I know I'm not the only one as I know others who have had this med for pain issues and it didn't work for them either. Absolute garbage, the U.S. FDA is garbage as well to allow this."

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62 Report
  • J in ...
  • Taken for 2 to 5 years
  • August 26, 2019

"I don’t know exactly what’s being put into the acetaminophen and hydrocodone pills these days, but I can clearly see that I’m not the only one that knows something is just not right! But please, people, listen to me when I tell you this: asking different pharmacies what the manufacturer of the pills they carry and asking if they have a different manufacturer of the medication can only get you barred from that location. Take it from me because I have one option in pharmacies these days that will fill my prescription. It’s crazy to me that you’re looked at as an addict if you want a specific generic that works for you. I mean, when did wanting to be pain-free make you a druggy (or junkie as I was referred to as)? But I feel like asking too many questions puts you on the 'do not fill' list, so tread carefully, people, or you may not be able to get anything. Much love, and I wish you all luck in a search for a life with no pain."

2 / 10
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77 Report
  • Bob
  • May 15, 2020

Norco (acetaminophen / hydrocodone) "Been on Norco 7.5/325 for 4 years . Had Spinal Fusion L4-S1 will never be the same . Norco has given me my life back . I am taking the Generic Version . For those of you complaining it DOES work . Be thankful you can get any Narcotics in todays world. They could say 800mgs of ibuprofen. Be thankful you are alive and kicking . Im 62 ."

10 / 10
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68 Report
  • Spike
  • April 24, 2019

"I've been on Watson acetaminophen/hydrocodone 10/325 for the last 8 years and it has been the best medication that has worked, then out of the blue this Mallinckrodt acetaminophen/hydrocodone brand came along, along with the medication not working nearly as well and having an upset stomach and Walgreens does not do damn thing about it. I'm stuck taking something that does not work and corporate America does not care about the little people, they just care about making more money."

3 / 10
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80 Report
  • Leigh
  • Taken for 6 months to 1 year
  • February 24, 2019

"Just picked up my script for generic Norco. Pharmacy filled it with the M366 (Mallinckrodt Pharmaceuticals brand), I’ve been trying to figure out why these pain meds aren’t controlling my pain. Spinal fusion, degenerative disc disease, spurs on my disc etc. after reading all the reviews, I now know why it’s not working! It’s trash! I took a pill 2 hours ago and still waiting for pain relief! Ugh!"

1 / 10
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78 Report
  • Patsy
  • Taken for 10 years or more
  • March 13, 2020

"Cambra acetaminophen/hydrocodone yellows t257 not effective. Lots of fillers causing side effects. Reported to rite aid, optum Rx, cambra and fda. Also people who comment if possible mention the pill ID number. There are many generics."

8 / 10
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66 Report
  • Tarheel...
  • Taken for 2 to 5 years
  • January 19, 2019

"I have been on Hydrocodone 10/325 for a couple of years due to back pain and now the need for hip replacement. About two weeks ago my wife and I switched our meds to a local Costco. My Hydrocodone was filled on the 10th of January and I began using it. The manufacturer that I had been on was from Actavis but Costco uses Aurobindo. I have noticed almost NO PAIN RELIEF from this manufacturer's brand of Hydrocodone. Further, I have had extreme sensitivity to light. After reading all of these other reports, I am convinced that Aurobindo, who now has purchased Mallinckrodt Pharmaceuticals, is producing and selling sub-par meds and will continue to do so until a recall is issued."

1 / 10
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76 Report
  • caddi...
  • Taken for 2 to 5 years
  • October 15, 2015

Norco (acetaminophen / hydrocodone) "Norco has been good to relieve my pain from my L2, L3, L4 discs herniated and resulting pain level 8 in lower back and down the sciatica nerve in my legs. Much better than morphine which makes me feel like I'm asleep and trying to move through cement. It really has done a good job of lowering the pain level and consequently I can function relatively well and get some things done each day, giving me a better quality of life instead of just focusing on the pain. I know I've become addicted but I'd rather be addicted to something that helps me than constantly suffer from pain and have misery day after day."

8 / 10
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107 Report
  • Tiltie
  • Taken for 10 years or more
  • April 12, 2019

"Have degenerative disc disease (arthritis of the spine), chronic pain, cervical nerve damage, on hydrocodone/acetaminophen (Vicodin or Watson) for pain 30 years. When given a new generic, had assumed just a very bad pain day, until I screamed, forced to leave cart in a store, shocked, embarrassed, and no food. Generic was Mallinckrodt. Life took a serious, horrible downturn. Weeks later found an old Vicodin (should have lost potency) but totally shocked at the relief it gave me. Tried, but lacked funds to have pill independently tested. Finally got back Watson hydrocodone/acetaminophen, until they too became unavailable. Now same nightmare with Aurobindo hydrocodone/acetaminophen. Tried an increase to no avail. Thank you for comments, so sorry for everyone's pain. Something must be done. I will contact the FDA, but sadly little hope, unless we stay persistent, demanding random testing, results published, along with exactly what fillers used (to track side effects). Otherwise, this will continue destroying lives. Do these generic hydrocodone with acetaminophen have any active ingredients in them?"

1 / 10
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73 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.