Acetaminophen / dichloralphenazone / isometheptene mucate for Headache User Reviews (Page 2)

• Bil...
• Taken for 10 years or more
• November 27, 2018

Acetaminophen / dichloralphenazone / isometheptene mucate "I suffered many years with migraine headaches so severe that they would render me useless for anything for a day or two. Because of the headaches, I would worry and be anxious about when the next one would come. As a result, they became more frequent, eventually occurring about once a week. I tried many pain-relieving drugs and doctors without success. Eventually, I found a doctor who suggested Midrin, even though he didn't know if it would help. He prescribed a total of 6 pills over a 5-hour period to relieve pain. I found that it completely removed pain after 1 tablet. I also felt more relaxed (less anxious). The headaches became less frequent to the point that I might go for a year without a headache. Just having the Midrin with me helped tremendously."

• Gab...
• Taken for 1 to 2 years
• May 8, 2014

Acetaminophen / dichloralphenazone / isometheptene mucate "I've had migraines for 15 years. Imitrex made me sick, so my neurologist prescribed Midrin. It's the only medication that actually relieves my migraines completely. I know they don't have the brand name Midrin, but in some places you can get the generic-Isometheptene/dichloralphenazone/acetaminophen. It has all the same ingredients and works great."

• Mot...
• October 21, 2016

Acetaminophen / dichloralphenazone / isometheptene mucate "Midrin works very well on the onset. Stops the 'gritty' pain and brings my headache/beginning migraine down to almost nothing. I do get a bit lightheaded and sometimes a bit amped, but it's totally worth it. I used to take 2 on the onset and rarely had to follow up in the next hour or two. Now I only take 1 on the onset and I'm fine. When the pill winds down, I feel tired, so when taking the pill, I plan on resting later that day and not to over-exert. I have Chiari I."

• Anonymous
• July 18, 2011

Acetaminophen / dichloralphenazone / isometheptene mucate "My wife has been taking Midrin for 15 years after trying this and this, oh, and trying this. 'It is the medicine for her.' And now we find out they took it off the market. It is the only thing she has taken that has worked. Thank you, FDA and DEA."

• Ama...
• May 6, 2016

Acetaminophen / dichloralphenazone / isometheptene mucate "This is a miracle drug! I've suffered with migraines for years, and I've never been able to find a medication that helps. I take 1 Midrin at the onset of a headache, and within 45 minutes it is gone. I have no side effects whatsoever. I can go about my daily routine, and the medication does not affect me at all. I highly recommend this medication! I was at my wit's end until I tried Midrin. Even Imitrex did not help me. But this drug did the trick!"

• ano...
• April 16, 2015

Acetaminophen / dichloralphenazone / isometheptene mucate "I've been taking Midrin for about ten years for my migraines. It works great if taken on time. When it was taken off the market, I went through so many trials and errors with different medications that were prescribed. Finally, after almost 2 years without Midrin, my doctor wrote me a script for Midrin and told me that I can take it to a compound pharmacy. But you have to pay out of pocket, which I do because it helps me so much."

• pre...
• January 25, 2011

Acetaminophen / dichloralphenazone / isometheptene mucate "I don't know how recent the comments are, but my daughter suffers with migraines, and Midrin is the only thing that we have found that gives her the relief that she needs to be able to function. I was informed last week that it is no longer being manufactured. We are so scared. I have tried to get it from every pharmacy in town."

• Suf...
• March 10, 2012

Acetaminophen / dichloralphenazone / isometheptene mucate "Midrin was the only thing that helped my migraines. Normally, only one pill took care of the migraine if I took it right away. And I had no side effects. I could work, drive, do everything with no problem. I had problems with other migraine medications, including bad side effects from the generic version of Midrin. But the name brand was great. I can't believe it was taken off the market."

• ceg...
• May 11, 2009

Acetaminophen / dichloralphenazone / isometheptene mucate "Midrin is the best medication I have taken for my migraines. As long as I take it at the first sign of a migraine, usually the aura, it goes away in about 20 minutes. I usually only have to take 2 for relief. I don't go anywhere without it."

• cot...
• April 13, 2011

Acetaminophen / dichloralphenazone / isometheptene mucate "I have been using this medicine for the last 7 to 10 years, and it has absolutely been a lifesaver. In the long, agonizing minutes of a migraine, nothing can compare to the relief you will get when you take Midrin, and the best thing is that it doesn't make you feel funny or bad afterward."

• Ind...
• October 26, 2010

Acetaminophen / dichloralphenazone / isometheptene mucate "I wanted to tell everyone that I was diagnosed with migraines about 12 years ago, and I was prescribed Midrin / Duradrin / Epidrin ever since. I can tell you that it is the MOST effective migraine medication that I have personally taken. My migraines have been so vicious over the last 12 years that I have tried EVERYTHING over-the-counter and prescription, trying to prevent them in the first place. I guess at this point in my life so far, nothing we have tried has really had any true success. Either the medicines I was taking to prevent them in the first place caused more side effects than what I could tolerate. I take 2 caps and feel relief usually within 30 minutes, and side effects are minimal."

• Jca...
• Taken for 10 years or more
• July 25, 2019

"I can so relate to everyone who have posted taken Midrin in the past. It was the only med that gave me relief. Now I’m taking Fiorcet T3, methocarbamol, and drinking whiskey more than I should. I am constantly dizzy and can’t function in my daily life. FDA, please pull your collective heads out of your asses and fix this. I’m begging you."

• Anonymous
• March 9, 2011

Acetaminophen / dichloralphenazone / isometheptene mucate "After trying at least ten prescribed medicines, I tried Midrin, and almost always it rids the worst of my migraine. The nausea and pain and aura go away. I just found out after using my last two Midrin, they are off the market. Wish I knew why or when they will be back."

• swi...
• April 8, 2017

Acetaminophen / dichloralphenazone / isometheptene mucate "I began having vascular migraines in the 70s, and nothing worked until I was prescribed Midrin. My rating is for the current Midrin formula as it doesn't seem to work as well as it did back in the day when I was first prescribed it... back then it far surpassed 10! It is still an effective migraine drug with fewer side effects than some other drugs that I was prescribed when Midrin was unavailable. It works quickly, and unless it is a really bad migraine, basically allows me to still be able to function once the headache subsides. Currently, my Medicare drug plan doesn't cover it, and it is expensive--- over $3.00 a capsule, unless you can find a coupon. Last time it was filled, I had a coupon and paid $1.12 a capsule."

• Rat...
• Taken for 1 to 6 months
• June 2, 2017

Acetaminophen / dichloralphenazone / isometheptene mucate "Like previous reviewers, I find the Midrin substitute hit-or-miss. Taking Midrin early or late in the headache seems not to matter; sometimes it works, sometimes it doesn't. I took Midrin in the early '80s, and it worked every time, and fast. (The effect was as if my head just floated away, but I could still function.) With the Midrin substitutes, the headache just slowly subsides. Either the formula is different or I am, but it's not the product it used to be. Still, it's the only thing that comes close to working for me."

• Tri...
• April 2, 2021

Acetaminophen / dichloralphenazone / isometheptene mucate "I've been taking Midrin for migraine, tension, cluster, and combination headaches for 31 years. Midrin is the only thing that actually works for my headaches, and I am still able to function at work as an RN after taking the Midrin. I've been begging my pain management doctor to send a prescription to a compounding pharmacy, but they want to play the game of prescribing things that don't work first because this has the isometheptene, which is a Schedule 4 controlled substance, which is the second lowest schedule."

• Anonymous
• April 5, 2011

Acetaminophen / dichloralphenazone / isometheptene mucate "Midrin worked so much better for my cluster headaches. Indomethacin temporarily relieved the headache, but the side effects of dizziness and fatigue were counterproductive. Midrin allowed me to function, and I felt refreshed and focused the morning after. I've been on many medications for my headaches, Midrin was the magic bullet. It's unfortunate I can no longer find it."

• Anonymous
• November 1, 2010

Acetaminophen / dichloralphenazone / isometheptene mucate "I opted to try Midrin because of its low side effects compared to the triptans. It works best when taken at the first sign of a headache, and I find that a cup of coffee not only speeds things along, it helps ward off the sleepy side effect. A piece of bread helps with the nausea that comes with a bad migraine. The best thing my doctor suggested was to keep a headache diary in order to find out what my migraine triggers are. That was a big help! Now I know what to avoid-anything with MSG, also called 'natural flavor,' and artificial sweeteners were THE WORST!"

• Car...
• Taken for less than 1 month
• September 20, 2018

Acetaminophen / dichloralphenazone / isometheptene mucate "I used to have bad migraines, and I could always count on Midrin to stop it in a short time. In the 1980s, when I took it, it would give you a distinct celery taste in your mouth as you felt your headache melt away. I eventually quit getting headaches...until recently. I was surprised that my doctors were unfamiliar with Midrin since it was so effective. But I was even more surprised to learn that Midrin, in its original form, was discontinued. Why? Anyway, tonight I bought a generic version, which was not covered by my insurance. No classic celery taste anymore, and it took a little longer, but my headache is 90% gone after 1 hour. Not as good as the original, but still a great med."

• Jay...
• September 18, 2010

Acetaminophen / dichloralphenazone / isometheptene mucate "I find that Midrin works as an abortive for my migraines when my preventatives fail. In fact, it works better than the triptans (i.e., Replax, Imitrex, Aexert) and equal to Toradol injections. I only need to take one or rarely two tablets to mitigate the worst of the symptoms. The only problem is that I sometimes get a bit dizzy and panic-prone as a side effect of Midrin. I know this is just mental, though, as I've taken the medication safely for many years. The relief the medication creates is sometimes incredible and worth the side effects. I find this medication also relieves my occipital neuralgia as well. I've never gotten rebound as I don't take it very often or need multiple doses."

• nur...
• February 16, 2018

Acetaminophen / dichloralphenazone / isometheptene mucate "Midrin was the most effective medication I've ever taken for migraine. I cannot take triptans as they cause my blood pressure to rise dangerously. When it was discontinued, I was given many other drugs to use without success. Now I stick with over-the-counter and suffer when they are ineffective."

• Tri...
• Taken for 10 years or more
• February 27, 2019

"I've been taking Midrin since around 1990. It's the only thing that works for my migraine, cluster, and tension headaches, and now I'm suffering daily from headaches and no relief due to the unavailability of Midrin and all generic forms of it. The FDA taking it off the market is a HUGE loss to headache sufferers all over. What a travesty and tragedy. What are you thinking?"

• Lad...
• Taken for 10 years or more
• September 23, 2020

"Migraines since my teens; clusters since 30; only efficient medication: Midrin. I now take ineffective triptans/opiates for migraines with aura. For clusters, total misery for days wishing I could pound my head against a wall till it stops. I’m disabled; can’t afford the formulation of Midrin. Knowing there’s medication that’s SAFE & EFFICIENT pulled for this reason disgusts me as an RN. I no longer work. 1 maybe 2 capsules, within 30 minutes I was a fully functioning acute care psych charge RN. I wonder if I won’t end up a patient due to lack of Midrin! FDA stop the refusing to reinstate Midrin, that has worked for years with no hangover effects, drowsiness, nor rebound migraines for me and for dozens, hundreds of my former patients. Migraines ineffectively treated can lead to suicidal thoughts and behaviors. What will it take before realizing the total cost of pulling this safe and efficient medication? Time to balance bureaucracy and red tape for common sense, decency, and patient experiences!"

• doc...
• Taken for 1 to 6 months
• April 11, 2017

Acetaminophen / dichloralphenazone / isometheptene mucate "For me, Midrin is very hit or miss. When I take it at the onset of a bad headache, sometimes the headache just in time vanishes before it ever begins. Then sometimes it's as if I took a placebo. Granted, the drug has 0 side effects for me. Overall, it's worth having if you have backup drugs for when it does not work. For those of you that, like myself, get a terrible trifecta of migraine, tension, and cluster headaches. You probably know, like me, that no meds really take the headache away completely once you have one."

• caa...
• June 25, 2010

Acetaminophen / dichloralphenazone / isometheptene mucate "I LOVE Midrin for headaches. I often get tension and cluster headaches and sometimes migraines, and I have tried TONNES of medicines (naproxen, diclofenac, Imitrex, ibuprofen, and all the over-the-counter medicines). Though it is not covered by my insurance, the cost (about $1 per pill) is WELL worth it. Midrin does not make me dizzy or tired. I usually only need one or two, and I have yet to have a rebound headache or upset stomach from it. I have been using it for years now. Ibuprofen does help in high doses, but anything over 400 mg makes me dizzy."