Tchp Chemo Regimen

Medically reviewed by Drugs.com. Last updated on Mar 10, 2025.

• Care notes
• Español

TCHP chemo regimen:

TCHP includes the following 4 medicines: Taxotere (docetaxel), Paraplatin (carboplatin), Herceptin (trastuzumab), and Perjeta (pertuzumab). Your doctor will prescribe the dose of each medicine and the infusion schedule. Infusions will happen in a hospital or cancer treatment center. The medicines need to be given on a fixed schedule. If you need to miss a dose, call your doctor or treatment clinic immediately. The following may repeat every 21 days for 6 cycles:

• Docetaxel IV over 60 minutes
• Carboplatin IV over 30 minutes
• Trastuzumab IV over 90 minutes for Cycle 1, then over 60 minutes for Cycle 2 (if tolerated), and over 30 minutes for all later cycles
• Pertuzumab IV over 60 minutes for Cycle 1, and over 30 minutes for all later cycles

Before you receive these medicines:

• Ask questions if you do not understand what your doctor or nurse is telling you about the medicines. Make sure you understand all the risks and benefits of this treatment.
• Talk to your doctor about all your current medicines and supplements. Do not take any medicines or supplements unless they have been discussed with your doctor.
• Tell your doctor if you have kidney disease, hearing problems, or an infection of any kind.
• Talk to your doctor about pregnancy. Medicines in this regimen may harm an unborn baby. Use an effective form of birth control during treatment and for up to 7 months after the last dose.
• Talk to your doctor if you are currently breastfeeding. Your doctor will tell you if it is okay to continue during treatment.

On each infusion day:

• Blood may be drawn to make sure the doses you are being given are right for you.
• Medicines may be given to help with nausea and vomiting and to decrease your risk for reactions.

Infusion precautions:

• Contact your doctor or nurse immediately if you feel short of breath or have trouble breathing during or after your infusion.
• Tell the doctor or nurse right away if you notice redness, pain, or swelling at the infusion site.
• Talk to your doctor before you get a flu shot or other vaccine. Tell your doctor if you have been around anyone who has chickenpox or any other infections. Do not have close personal contact with anyone who has recently received an oral polio vaccine.

Drugs used to treat this and similar conditions

After infusions:

• If possible, have someone stay with you to call for help if you have serious side effects.
• Drink extra liquids to help prevent nausea and to keep your kidneys and liver working well.
• You may be at risk for infections. Wash your hands often with soap and water. Do not have close contact with anyone who is sick. Ask your doctor about vaccines you may need to prevent infections.

Call your local emergency number (911 in the US) if you have any of the following:

• Chest pain
• Trouble breathing
• Hives, swelling in your lips, face, or throat, headache, lightheadedness, fainting, flushing
• Blistering, peeling, or red skin rash

Call your nurse or doctor immediately if you have any of the following:

• Numbness, tingling, or burning pain in your hands, arms, legs, or feet
• Ringing in your ears or trouble hearing
• Rapid weight gain, or swelling in your hands, ankles, or feet
• Bloody or black, tarry stools, or blood in your urine
• Blurred vision, loss of vision, or vision changes
• Severe stomach pain, vomiting, or watery or bloody diarrhea
• Severe tiredness or weakness

Talk to your nurse or doctor if you have any of the following:

• Unusual bleeding, bruising, or weakness
• Change in taste, nausea, vomiting, loss of appetite, constipation, or diarrhea
• Joint or muscle pain
• Sores or white patches on your lips, mouth, or throat
• Redness, pain, or swelling where the IV needle is placed
• Fever, chills, cough, runny or stuffy nose, sore throat, and body aches
• Hair loss or nail changes

Follow up with your oncologist as directed:

Your progress will be checked during regular visits. Blood tests may be needed to check for side effects. Write down your questions so you remember to ask them during your visits.

Care Agreement

You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

© Copyright Merative 2025 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer