Generic Akynzeo Availability
Last updated on Apr 10, 2025.
Akynzeo is a brand name of netupitant/palonosetron, approved by the FDA in the following formulation(s):
AKYNZEO (netupitant; palonosetron hydrochloride - capsule;oral)
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Manufacturer: HELSINN HLTHCARE
Approval date: October 10, 2014
Strength(s): 300MG;EQ 0.5MG BASE [RLD]
Is there a generic version of Akynzeo available?
No. There is currently no therapeutically equivalent version of Akynzeo available in the United States.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Akynzeo. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: Generic Drug FAQ.
Related patents
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
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Crystalline forms of an NK-1 antagonist
Patent 10,233,154
Issued: March 19, 2019
Inventor(s): Bacilieri Christian & Frasca Gionata
Assignee(s): Helsinn Healthcare SAThe present invention is related to crystalline forms of 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide which is an NK-1 antagonist useful in the treatment of induced vomiting and other disorders.
Patent expiration dates:
- September 25, 2035✓
- September 25, 2035
-
Crystalline forms of an NK-1 antagonist
Patent 10,676,440
Issued: June 9, 2020
Inventor(s): Bacilieri Christian & Frasca Gionata
Assignee(s): Helsinn Healthcare SAThe present invention is related to crystalline forms of 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide which is an NK-1 antagonist useful in the treatment of induced vomiting and other disorders.
Patent expiration dates:
- September 25, 2035✓✓
- September 25, 2035
-
Compositions and methods for treating centrally mediated nausea and vomiting
Patent 10,828,297
Issued: November 10, 2020
Inventor(s): Trento Fabio & Cantoreggi Sergio & Rossi Giorgia & Cannella Roberta & Bonadeo Daniele
Assignee(s): Helsinn Healthcare SAProvided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- December 17, 2030✓
- December 17, 2030
-
Crystalline forms of an NK-1 antagonist
Patent 10,961,195
Issued: March 30, 2021
Inventor(s): Bacilieri Christian & Frasca Gionata
Assignee(s): Helsinn Healthcare SAThe present invention is related to crystalline forms of 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide which is an NK-1 antagonist useful in the treatment of induced vomiting and other disorders.
Patent expiration dates:
- September 25, 2035✓✓
- September 25, 2035
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 11,559,523
Issued: January 24, 2023
Inventor(s): Trento; Fabio et al.
Assignee(s): Helsinn Healthcare SA (Lugano/Pazzallo, CH)Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- November 18, 2030✓✓
- November 18, 2030
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 12,042,494
Issued: July 23, 2024
Inventor(s): Trento; Fabio et al.
Assignee(s): Helsinn Healthcare SA (Lugano/Pazzallo, CH)Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- November 18, 2030✓✓
- November 18, 2030
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 8,623,826
Issued: January 7, 2014
Inventor(s): Trento Fabio & Cantoreggi Sergio & Rossi Giorgia & Cannella Roberta & Bonadeo Daniele
Assignee(s): Helsinn Healthcare S.A.Provided are methods for treating nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery, comprising the co-administration of netupitant, palonosetron and dexamethasone.
Patent expiration dates:
- November 18, 2030✓
- November 18, 2030
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 8,951,969
Issued: February 10, 2015
Inventor(s): Trento Fabio & Cantoreggi Sergio & Rossi Giorgia & Cannella Roberta & Bonadeo Daniele
Assignee(s): Helsinn Healthcare SAProvided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- November 18, 2030✓
- November 18, 2030
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 9,186,357
Issued: November 17, 2015
Inventor(s): Trento Fabio & Cantoreggi Sergio & Rossi Giorgia & Cannella Roberta & Bonadeo Daniele
Assignee(s): HELSINN HEALTHCARE SAProvided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- November 18, 2030✓
- November 18, 2030
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 9,271,975
Issued: March 1, 2016
Inventor(s): Trento Fabio & Cantoreggi Sergio & Rossi Giorgia & Cannella Roberta & Bonadeo Daniele
Assignee(s): HELSINN HEALTHCARE SAProvided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- September 9, 2031✓
- September 9, 2031
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Compositions and methods for treating centrally mediated nausea and vomiting
Patent 9,943,515
Issued: April 17, 2018
Inventor(s): Trento Fabio & Cantoreggi Sergio & Rossi Giorgia & Cannella Roberta & Bonadeo Daniele
Assignee(s): Helsinn Healthcare SAProvided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
Patent expiration dates:
- November 18, 2030✓
- November 18, 2030
-
Crystalline forms of an NK-1 antagonist
Patent 9,951,016
Issued: April 24, 2018
Inventor(s): Bacilieri Christian & Frasca Gionata
Assignee(s): HELSINN HEALTHCARE SAThe present invention is related to crystalline forms of 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide which is an NK-1 antagonist useful in the treatment of induced vomiting and other disorders.
Patent expiration dates:
- September 25, 2035✓✓
- September 25, 2035
More about Akynzeo (netupitant / palonosetron)
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- Drug class: miscellaneous antiemetics
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Glossary
Term | Definition |
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Drug Patent | A drug patent is assigned by the U.S. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation. |
Drug Exclusivity | Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. |
RLD | A Reference Listed Drug (RLD) is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application (ANDA). By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.