Can I take Zofran with Wellbutrin?

Hi, Sivart!
There is a slight risk of a rare but serious condition called serotonin syndrome:
https://www.drugs.com/interactions-check.php?drug_list=1752-1120,440-203
If your doctor prescribed them it's because they've determined the benefit outweighs the risk. If the Zofran is something you had before and want to give it a try you should ask your doctor or pharmacist for their professional opinion first.