My doctor started me on 25mg. of zoloft for 7 days. I had very bad headaches and loss of appetite. After 7 days he increased it to 50mg. and thats when the severe nausea started so he said to stay with it another week (50mg.) and gave me some nausea pills to take to see if that would help. I will be at the end of 3 weeks once this week ends. Is this normal? I don'y know whether to cut back to 25mg. or stay with the 50mg. How long does this last before these side effects go away as the last 4 days I have had the runs as well? How long should I hang in there. Is there anyone that can answer my problem and tell me when this will stop or if I should lower my dose or remain on the 59mg. for another week to see if the symptoms stop.