... polycythemia vera last december 2011 from then on i am on my 19th sessions of phlebotomy and in and out of the hospital due to unstable platelet,i am taking hydroxy 3x a day and thromboreductin once a day,i never smoke and drink alcohol and so active ,i dont have idea where i gt this kind of illness but i got no choice but to accept it ,i am hearing opinions about people taking hydroxy and some told me that it will lead to some serious illness like cancer or leukemia ... im confused... i just noticed that im having hair loss and my nails are turning into having like poor blood circulation after taking hydroxy
Taking hydroxyurea can cause nail discoloration(black spot) and hair loss? I ws diagnosed of having?
Question posted by maryannesteiner on 30 May 2012
Last updated on 11 June 2017 by mevin
3 Answers
mevin
11 June 2017
Hi am also sufering from policythemia. And also taking hydrea. Not smoke not drink alcohol. Any sugestion how to gret cured
aramanarao
31 May 2012
Hi Maryannesteiner, I am surprised by the dosage of Hydroxyurea recommended. Be that as it may, has your hematocrit levels gone down after consuming hydroxyurea ?? Also why was thromboreductin prescribed for you ?? I am told that hydroxyurea reduces your hematocrit level (just like phlebotomy) so that the ailment does not progress into cancer or leukemia.
Nail discoloration and/or hair loss may be because of high dosage of hydroxyurea and/or simultaneous consumption of thromboreductin. Please double check with a hematologist.
maryannesteiner
2 June 2012
@aramarao,
hi aramarao.i just had my usual friday check up and my labtest is quite okay yesterday my hematocrit is 0.42(0.37-0.47 for female) so its really normal, my hemoglobin is 134 before it was really 6 times higher... my only problem now is my platelet yesterday it was 880.0 it is double the normal rate,i dont take thromboreductin anymore i only took that when i was admitted for a week bcoz my platelet was way too high ... im taking my hydroxy 3x a day mwf and 2x a day tths... im having pains all over almost everyday and so weak to do things i easily get tired ,i do excercise too but sometimes it causes me having more pains on my bones and muscles... stiffneck and dizziness are also common to me ,its good to have joined here it gave me so many ideas about having this kind of disorder,it helps me a lot ...
I wish you all well with your journey with this disorder. Stay positive and enjoy every day as best you can.
godbless us all... and thank u so much for answering my question... looking forward on talking to u again... im open for all suggestions and informations that could help me... :)
kaismama
30 May 2012
Yes, in rats they can get cancer if given 3 times the human dose. It says they haven't done alot of studies in humans, but I'm sure it has happened in long term use and the reports are anecdotal. And yes, it can cause darkening of your nails and hair loss. Here's a web site about it.
https://www.drugs.com/pro/hydroxyurea.html
maryannesteiner
30 May 2012
thank you so much for this very helpful information...
Related topics
polycythemia, polycythemia vera, hydroxyurea
Further information
- Hydroxyurea uses and safety info
- Hydroxyurea prescribing info & package insert (for Health Professionals)
- Side effects of Hydroxyurea (detailed)
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