Spironolactone - Will weight gain with aldactone usage go away once the body adjusts?

After going to my PCP, my OB-GYN, and my Cardiologist who all blew me off with the "it doesn't cause weight gain" even though my scale said 154 and I was eating more clean and was more active than I've ever been in my entire life. I finally found a new OB-GYN who tested my hormones and cortisol (testosterone nearly zero; cortisol high), and also did a full thyroid panel... T4 and T3 also very low (other docs tested only TSH which was on the high side but "normal" so proclaimed "just fine!"). I've been on NP Thyroid and Testosterone for about 6 weeks now and I feel like I'm slowly, so very slowly, pulling out of this slump. Scale has not budged but I am feeling less sluggish and looking not quite as squishy in my mid section. Dr. may consider adding progesterone to my therapy as well when I get my labs done in another 4 weeks. I hope this provides some positive hope to others. Find a doctor who will test your hormones and do a full thyroid panel. This stupid med can wreak HAVOC on your hormones which can also cause a domino effect. The gas lighting by the doctors when you raise your concern makes it 1000x worse. I am furious with myself for not researching this first. I hope this helps others doing their research.

Like a lot of you, I've tested for thyroid issues, came off my birth control, paid close attention to my diet and exercise to see what I was doing wrong and here we are. I stopped taking spiro about 3weeks ago and I actually gained another 5lbs in the first couple days.
I'm going to chug through and pay attention to my diet and exercise…mood etc so that I can post an update about when I finally regulate.
So far my mood seems better and libido is back. Period is still MIA and weight is here.

I am also a Hashimotos/Hypothyroidism patient on Synthroid, so I assumed this was a thyroid issue for many months. After checking that several times, getting healthy results, I finally looked into spiro and weight gain.

I was in shock seeing what you all have gone/are going through and what I had just experienced all from a medication solely for ACNE. It’s so incredibly aggravating and believe me I understand the frustration and emotional rollercoaster the weight gain and weight loss resistance from this medication causes.

Here’s what I did: after constant research, it became apparent that spiro can cause estrogen dominance/low progesterone. I had my hormones checked and we found that my progesterone was basically nonexistent, but my estrogen was fine, resulting in estrogen dominance. So for 12 weeks/3 cycles, I took bio identical progesterone to help balance. We’ve achieved that, and about a week ago, for the first time in over a YEAR, the scale has started to slowly trend downward. I don’t wanna speak too soon, but I do feel confident that I’ve reached full recovery from these meds.

Obviously the only way to lose fat is to be in a caloric deficit so I’ve gone about this through diet and calorie restriction. Not weightlifting at the moment. Even a month ago, calorie restriction still didn’t work for me. The scale wouldn’t budge. So now that it is, I can say to just give it time and get treatment if needed to help speed up the balancing process. See a HORMONE SPECIALIST. It’s obviously a matter of patience and letting your body figure itself out.

Don’t worry and don’t think you will never lose fat again. You will and it just takes time to adjust back to a healthy balance. Expect to get back to your old body and KNOW it will happen because that helps speed up the process too. Our minds are powerful and what we tell ourselves, we experience. If you have any questions, feel free to reach out. Sending love and positivity to you all!

Even a couple of months before the weight gain started, I've noticed that the top of my feet were slightly swollen. The swelling doesn't seem to dependent on sth. I've always had thin feet where you could see every bone and tendon.

It's also very, very soft and wiggly. When I tip slightly against one side of my stomach I can see and feel it travelling to the other side. When I tip against my knee it travels up my whole thigh. Like if you throw a stone into water creating waves. Same on my arms and back. My normal body fat is more thick. I suspect it's water.

Decreasing my calorie intake down to only 500 kcal/day for months didn't do much even though I can say that I lost a little bit of weight. But I still don't recognize myself.

I recently switched to drospirenone (progesterone which is related to spironolactone) as I suspect the weight gain was due to low testosterone and high estrogen. I think it's getting better, but it's too early to say for sure..

I do not over eat, in fact I don’t eat anywhere near as much as I should for my height. There is no reason whatsoever for my recent weight gain.
Being overweight does not run in my family either. I recently tried stopping the
prescription Spironolactone, unfortunately my cystic acne returned immediately so I had to start taking it again. I would love to find a good alternative for this prescription.

I've always been skinny until August of 2018. I started gaining weight like crazy. August 2020 I'm now 30 lbs heavier and absolutely disgusted with myself. I went to 4 different endocrinologist who said all of my blood work was fine. I asked my dermatologist several times of spironolactone could make you gain weight and each time he assured me it wasn't the problem. Just like everyone else on this forum, my weight gain is in my stomach, butt, thighs and boobs. I recently went to a new gyno who put me on testosterone cream because mine was non existent because of the spironolactone. Some talk about sex drive, what is that lol. I felt better on the testosterone cream but still not happy and very over weight. Well I was recently hospitalized and didn't take spironolactone for 5 days. I noticed I wasn't as depressed and I actually had energy. My dad and husband noticed a difference in my attitude while in the hospital. I decided to take spironolactone once I was discharged and noticed my depression and lack of energy came back instantly. As of 2 days ago August 23rd, I quit it cold turkey and I feel so much better. I'm so scared I won't be able to loose this weight. I don't want to look like a model, I just want to fit back into my clothes and not hide from everyone because of my weight. I will continue with the testosterone cream and hopefully that will help me drop this excess of 30 lbs.