Does spironolactone cause weight gain?

You'll want to speak to your physician about whether or not spironolactone is the culprit here or not. For some women, anti-androgens do cause weight gain, yes. I see this not only with spironolactone but also other antiandrogens. There are mny causes of weight gain and you'll want to consider having a thorough review by your doctor.

DrDonovan