I used capsaicin liquid on my elbow about ten hours ago. When I took a shower and washed the application site it caused extreme heat and redness on my skin.
How do I neutralize capsaicin topical liquid that has been applied on the skin?
Question posted by ocdmax on 25 June 2012
Last updated on 27 June 2023 by Q_S
I found a solution! I bathed the area with vinegar and within minutes it stopped the intense burning, and after 30 minutes the redness was gone. Thanks to all who responded to my question.
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14 Answers

The most common side effect of capsaicin use is a feeling of warmth and stinging, or a sensation of burning after application. This sensation is related to the action of capsaicin on the skin and is to be expected. Approximately 50% of patients will experience some mild to moderate stinging or burning. This sensation usually diminishes after the first few days of application and in most cases will disappear with time and continued use.
Methods used to reduce this sensation include:
Avoid taking a hot bath or shower just before or after applying capsaicin cream.
Try to keep cool, do not wear tight clothing or become too warm as heat may increase the sensation.
Maintain your recommended or prescribed dosing schedule as reducing the number of doses you use each day will not lessen the sensation and may lengthen the period of time that you get the sensation.
Has anyone had this problem with household objects and clothes? My family member used to use capsaicin ointment, now a thin layer of burning substance is settled deep into towels, bedsheets, clothes, etc. No amount of washing or double washing them has helped. I'm desperate at this point
What worked on both the skin and the mouth? Hydrogen peroxide.
It turns out that peroxide reacts with capsaicin molecules, changing their structure and rendering them incapable of bonding with our receptors. Peroxide works even better in the presence of a base like baking soda: We found that a solution of 1/8 teaspoon of baking soda, 1 tablespoon of water, and 1 tablespoon of hydrogen peroxide could be used to wash the affected area (or as a mouthwash (swish vigorously for 30 seconds) to tone down a chile’s stinging burn to a mild warmth. (Toothpaste containing peroxide and baking soda is a somewhat less effective remedy.) Always keep peroxide, baking soda, and toothpaste away from your eyes. Found this remedy at cooksillustrated.com/how_tos/6651-lessening-a-chile-peppers-burn-on-skin-or-in-mouth
A must read!!
HELLO!!
I rubbed a lot of this stuff on my knee and it proceeded to burn VIOLENTLY. I used apple cider vinegar, tea tree oil soap, dish soap, Benadryl, baking soda and nothing worked UNTIL--- NEUTRAGENA ACNE FACIAL SOAP!!! if you have a face soap it usually tries to get rid of the oils. INSTANT RELIEF!!
White Vinegar applied with a sponge worked best for me. It took the immediate deep hot away. I reapplied several times when it felt like it was heating up. Washing the area in cool water & dawn dish soap before the vinegar was probably a mistake as I felt like it spread the hot area. After washing with soap & water, I tried putting yogurt on the spot which felt good, but as soon as the yogurt was at body temp It started feeling hot again & It did not neutralize the area. I feel like the vinegar stopped the level of burning & the burning became less after each application. I wish I had read about the vinegar solution first.
Dr prescribed zostrix for my husband to put on desired areas of back and neck for headaches, I applied the ointment bare handed - nothing bothered me.. well in his sleep he sweated all that hot ointment onto my right arm I woke up in tears from the burning, it felt like someone had a butane torch hovering over my arm. So at 2:40 am I washed my arm with dial soap 3x and patted dry . I didn’t feel any relief but I laid back down to wait, about 15 minutes later it finally went away.
Dial soap with cold water solved it just realize it is not immediately that you will notice - give it a few minutes to cool off
I applied a thick baking soda and water solution to the impacted area on the back and sides of my right calf. I followed it with an application of 2% milk. There was immediate relief, but in 15 minutes, the burn was back. I then wiped it down with white vinegar. It feels so much better! Thanks to all who submitted answers.
I mixed baking soda and sour cream in a 2:1 ratio and applied for immediate relief. I refrigerated the rest to reapply as needed.
I was ill advised to put this on a shingles rash. The capsaicin cream ended up making shingles feel like nothing. I never experienced so much pain. Putting the affected area in front of a fan helped greatly, then we found some greek yogart in the fridge. That worked great.
I suffer from chronic pain in the joints which include the knees, wrists, elbow, back, neck. It must be from my Army days of humping it for miles with my ruck. The VA gave me Trixacian HP which is a .075 capsaicin lotion for pain when it flares up.
I made the mistake of vigorously appling it it to my hands, wrist, and elbows last night before bed after a shower. When I woke up around 5am, I found those areas feeling like they were on fire.
I ran across this site to say the apple cider vinegar does help relieve the burning sensation. I also used sour cream after which took the burning sensation away as long at it was cool. I still have a slight burning sensation, but not like before. I may re-apply above later if the burning becomes intense again.
I hope this helps for whomever has made an honest mistake like I did. I think I will stop using this cream. It does work, you won't feel joint pain, but the cost is to painful to bare.
Best of luck,
Geo
Feel sorry for the hemroid cram guy but white vinegar helped but if you can't find any I also recommend wd40 it cools it down and helps get rid of the oil
Mistakenly used Capsazan for a hemmeroid cream... BIG MISTAKE!!!
Vinegar as suggested above helped a little but sour cream really did the trick and nearly instantly!!
Vinegar/apple cider vinegar/milk all work! I was out of vinegar/milk so i used apple cider vinegar. I put my feet (where I applied the capsaicin cream) in the tub and poured a little bit over the affected area. I reapplied 2 mins later, gentle rub, fresh cool water rinse and lo and behold, done deal :)
Note: Do not go for the aloe vera! (contraindicative, cooling,,, Yea... Not!!! ). When in doubt, no computer access, contact local law enforcement training officer or unit, they constantly train with capsaicin.
References:
My mom, this website, 50 years of trial and error, law enforcement and Combat Search And Rescue swimmer/crew chief.
Hello Richard. I really appreciate your advice. I really wish I had found this sooner since I did put the aloe vera on before I came to the internet. lol I am still burning but I think I read your post wrong. I mixed the vinegar and the milk. Should I have done that? Boy do I feel stupid. Oh and burning and stinging. I thought it might help my TMJ. Wrong. Thanks again.
Can I use just any milk or there is a particular one
genra, I believe any milk would do. I used Great Value 2% from Walmart. Funny thing is I thought Richard meant to mix them together. It made it thicker so it wasn't as runny. It also took at least 3 applications. I reapplied after 10 minutes. The first application took the sting but it was still sore so I did it a couple more times and then I could sleep. Works great.
Your Answer:
2 words - VEGETABLE OIL!
First, I'm so sorry to hear this happened to you also. It's been about 2 yrs now since it happened to me.
I get very painful, severe stress knots in my shoulders and neck, which turn into migraines. So I was looking for relief.
I bought some to have on hand the next time I needed pain relief. I woke up at 5 a.m. not long after buying it in pain again. I applied it to my neck and shoulder areas and my knee for unrelated arthritis pain I have daily. I washed my hands very well. Finally laid back down at 6 a.m. not really feeling any relief.
At 7 a.m. woke up feeling a lot of discomfort in the areas I had applied the creme.
It quickly escalating to extreme pain. Tried showering but soap and water didn't help, actually seemed to make it worse. About to go to the hospItal when I remember I could call "Ask a Nurse" with my insurance company.
She asked if I had tried soap and water. Then told me to get the VEGETABLE OIL from the kitchen and pour it all over the effected areas. I climbed back in the tub and poured it on. Within minutes the pain started to subside, I still had tenderness like a sunburn and very red, but nothing like it had been.
Also, no blisters. Both my knee and neck areas hurt equally as bad so it's not just the more tender area's for me it effects badly, its every where. I try to warn everyone to test it first before using it on a large area.
I'm sure this is too late to help you, but hopefully will help some other person in terrible pain. I know I wouldn't wish it on my worse enemy.
Aces88TX
Thank you for the help, I had no idea this would happen. The nurse at my Doctors office recommended this. I have shingles, who uses this stuff? The last thing I needed was more agony.
Try some milk on the area, as that helps with burning caused by hot peppers. That is what the active ingredient is made from in this med. wet a cotton ball with milk and put it on the area, if it burns worse, seek medical attention. Patti
Thanks so much. The milk really worked.
Related topics
Further information
- Capsaicin uses and safety info
- Capsaicin prescribing info & package insert (for Health Professionals)
- Side effects of Capsaicin (detailed)
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