I am on 50 mg, newly prescribed about a month ago. I did sleep deeply at first, even came down 1/3 of my Ativan dose. However... I am experiencing intense anger, and the lethargy is so miserable to deal with. I have bipolar disorder, and suffer from racing thoughts in the middle of the night. At first I thought Seroquel was an answer to prayers, but has anyone felt more edgy on it? Will that go away? Thanks very much.
Is it possible that seroquel can make you more edgy or intense?
Question posted by IrishRosa11 on 12 Sep 2011
Last updated on 17 December 2018 by Rocky4
6 Answers
Rocky4
17 Dec 2018
No
sixie6e
4 Nov 2017
yes. the next day I have an intense rage and zero tolerance for frustration. I am prescribed 300mg per night but now only take maybe 50mg and soon will replace with strictly marijuana. quetiapine is supposed to be an antipsychotic...
lew85x
1 Aug 2016
Hi i have been perscribed 25mg quietapine at night 2 if required. I have been taking these for 4 weeks i am like a zombie all day dry mouth stomach upset anxiety increased and agitated. Such horrible tablets will these side affect settle? Diagnosed with bi polar 2.
Beefy Norm
17 May 2018
I've been on it for almost a year. Although I have serious, but previously manageable manic depression I have chosen to stop Seroquel immediately. My psychiatrist swears by it, but my sister in law psychology/addictions LPN of 45 years swears at it. It simply will not work and has a totally opposite effect in a majority of patients who use it. Sis also advises to not follow doctors unconditionally as some of them can be stubborn about how long to use a medication before seeing it as a hazard. In my opinion, just stop taking it the minute you feel out of control. Because, even in an already altered mind-set you can tell that your reactions and behaviors are unacceptable.
I did the sudden stop method and had some initial sleeplessness that went away quickly.
puckiemull
13 Sep 2011
Hi IrishRosa,
I am also on seroquel,i was upped to 300mg few months back and i am now trying to get off it,i'm down to 150mg and i feel rotten on it,dont feel like doing anythin,have lost the will to get up and go.Its not helping me sleep at night,it seems to have the opposite effect on me that it should have!
I suffer from anxiety/panic disorder,depression and ocd,my pysch put me on this to help me wiith sleep but it's not working,i think it made everything worse.
Many have great luck while on this med,but i for one am miserable on it.
Talk with your doc,try come off it,thats all i can advise to you.
Take care my friend
cetteferge
13 Sep 2011
Hi Irish - I take about 100-150 mgs. Seroquel each night for 14 years now. Its important to go right to sleep the minute you feel the Seroquel start to work... don't fight it. Because I'm a night person, I used to fight the feelings of getting sleepy if I thought I could get one more thing done... just habit. Then, I realized that there was a bounce back affect of the Seroquel, so that I started to have racing thoughts, if I didn't give in to the sleep immediately.
I'm bipolar I. I also have heard others say, and its happened to me that I need a good 8 hrs. sleep, almost to the second. I used to get by on 5-6 hrs./night before medications, all through college, grad school, but I must have 8 hrs. now... just like clock work. Yes, I had the anger, too... almost rage. That went away except for the occasional outburst! Try to give it a few months unless its really unbearable. And, diet + excercise, a little walking daily, helps. Hope that helps. Good Luck!
LaurieShay
12 Sep 2011
Hey IrishRosa,
Yes, it is possible that Seroquel can cause adverse mood changes. You need to let the doctor know if this persists. Some people just can't tolerate the tiredness that Seroquel causes and the irritability definitely needs addressed by the doctor.
Best wishes,
Laurie
Related topics
ativan, seroquel, bipolar disorder, sleep disorders, sleep, fatigue, anger
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