I got Synvisc One injection from Dr. on April 21, 2011. He gave it like an ordinary injection in the knee and said Synvisc One will go in the knee joint on its own. I feel injection is not in the joint, I have severe unbearable pain in the knee, very stiff burning pain, cannot walk and find difficult to drive . At times I feel like throwing up. After I complained to Dr. O\Brian he told me that he cannot do anything for me and go to family Dr.. Family doctor knows little about this injection I don’t know what to do. I don’t know what kind of side effects this material has and how long this will go on. Please help. Called Genzyme many time. No help.
I am having severe pain after the injection?
Question posted by sippy2011 on 27 May 2011
Last updated on 19 November 2021 by ChronicPain2
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
5 Answers
ChronicPain2
19 Nov 2021
I sympathize. I too was brushed off by the orthopedic MD who injected my knees with Synvisc or Synvisc-One and a few weeks later I'm in agony. His staff set up an apt. but it was pointless. He told me to contact my primary care doctor. I did, nothing yet.
The worst part of my followup visit with my Orthopedist was that he discounted the severity of the pain I'm having, and said it could NOT be from the Synvisc and NOT an infection. He told me that if it were an infection my leg would be the size of a balloon. OK, not an infection then, but WHAT? He wouldn't say anything about it or give me information on what to do.
I continue to have extreme leg muscle tightness, pain and difficulty walking. Its like being on that medieval torture device known as 'the rack'.
michelle2012
8 March 2012
Hi, I had my first injection out of 3 yesterday. First time getting it. Was very nervous, and told Dr i was. He said to just relax or he cant put the needle in. He had to put it in 2 times, because i wasnt relaxed enough. Finally i was relaxed enough and he put it in. It felt very werid, and i felt the stuff going into my knee cap. It didnt hurt as he put some freezing in. After it was done, i walked out, and it felt werid. about 2 hours later i started to feel alittle bit of pain. I kept walking on my knee to help with the pain. I had to take 2 tylonals for the pain. Laying in bed made my knee feel better. Today it feels better then it did yesterday. 2 more injections to go!! I hope you feel better soon.
GrandmaSher1966
3 Oct 2021
So sorry for your experience. I have bone in bone OA in both knees. They use an ultrasound to find”sweet spot”. I have horrible pain for a few days up to a week until bruising goes down. I elevate &:Ice kneem24-48:hrmafter each injection, given a week apart. I am also careful not to overdo exercise until the gel has a chance to get where it is needed. ONE time I had an issue when they hit a nerve by accident. I ONLY go to my Arthritis Dr for this,as it is only one I trust. Have been successful 90% for past 9 years.
Inactive
28 May 2011
It has been over a month since your injection - I would be very concerned. If your orthopedic Dr that gave you the injection does not respond to you - I would seek out a second opinion with another orthopedic Dr. It is not likely that one doctor will speak against another but hopefully they will help to figure out what the problem is. I would not just let it go. If the area is warm and inflamed and/or you start running a fever get to a doctor or emergency room right away. It could be infected, although if it was that probably would have shown up by now. Anyway, you have to do something and a second opinion is a good place to start.
sippy2011
29 May 2011
My problem is that as soon as you mention that Dr. did not follow any of the instructions for the injection and gave it as an ordinary injection. He gave in the nerve on the outer side of my knee. that is why it is hurting like a knife because it is a nerve pain . He really wanted to cause me permanent pain. He succeeded in doing that. In Canada we have no place to complain. I once complained against a Dr for operating on me for 10 times for ingrown toe nail. Since then I cannot get any treatment in Canada. I have gone many times out of canada for treatment. This Injection is the result of that complaint. It was my stupidity that I was impressed by his sweet manners and started trusting him. I did not know he will do this behind my back after taking me into confidence. While giving injection he commented - oh expensive stuff, gold. I did not like that. People in USA are very lucky to have the best medical system and where the doctors are answerable for their actions.
Same day this Dr. told me after looking at my L knee x-rays that the knee replacement which I had outside canada was partial and not total. I was upset and wrote to the Dr. who had replaced my knee for cheating me. After 3 weeks I saw another surgeon for my back and asked him to examine my L knee x-rays and he told me that I had total knee replacement and not partial. I was shocked and still do not know how to address this issue before him or any other Dr. in canada. I am afraid if I do that as a retaliation they will try to harm me more. They are not answerable to anyone.
pamalam601
1 May 2013
I agree with above answer. Keep in mind that not all doctors are equally skilled at administering this injection. When the doctor is referring you to your primary physician to take care of a procedure that HE just performed, something is definitely wrong! Go to emergency immediately, and he should be reported!
Inactive
28 May 2011
I have read some info about this inj. I have copied & pasted below, hope this helps you:
In clinical trials, the most commonly reported adverse events were transient local pain, swelling, and/or effusion in the injected knee. In some cases, these symptoms have been extensive. Other side effects such as rash have been reported rarely. Synvisc is contraindicated in patients with known hypersensitivity to hyaluronan products or patients with infections in or around the knee. Health Care practitioners should exercise caution when using Synvisc in patients allergic to avian proteins, feathers, or egg products; who have evidence of venous or lymphatic stasis in the leg to be treated; or who have severe inflammation in the knee joint to be treated. Patients should be advised to avoid strenuous or prolonged weight-bearing activities after treatment. Strict adherence to aseptic technique must be followed to avoid joint infection.
The safety and effectiveness of Synvisc in children and in pregnant or lactating women have not been established. It is unknown whether Synvisc is excreted in human milk.
About Genzyme
One of the world's leading biotechnology companies, Genzyme is dedicated to making a major positive impact on the lives of people with serious diseases. Since 1981, the company has grown from a small start-up to a diversified enterprise with more than 9,000 employees in locations spanning the globe and 2006 revenues of $3.2 billion. Genzyme has been selected by FORTUNE as one of the "100 Best Companies to Work for" in the United States.
With many established products and services helping patients in nearly 90 countries, Genzyme is a leader in the effort to develop and apply the most advanced technologies in the life sciences. The company's products and services are focused on rare inherited disorders, kidney disease, orthopaedics, cancer, transplant, and diagnostic testing. Genzyme's commitment to innovation continues today with a substantial development program focused on these fields, as well as immune disease, infectious disease, and other areas of unmet medical need.
This press release contains forward-looking statements, including statements about: whether and when Synvisc-One obtains marketing approval in the US, whether a single-injection regimen of Synvisc will reduce costs and burden, and provide additional options for physicians, and the timing of a regulatory filing for Synvisc-One in Europe. These statements are subject to risks and uncertainties that could cause actual results to differ materially from those projected in these forward-looking statements. These risks and uncertainties include, among others: extent to which the US Food and Drug Administration determines that Synvisc-One can appropriately be approved for marketing in the US, the extent to which the government and private insurers recognize the benefits of Synvisc-One and maintain or otherwise implement reimbursement policies that reflect these benefits, our ability to prepare the necessary regulatory filing for Europe in a timely fashion; and the risks and uncertainties described in reports filed by Genzyme with the U.S. Securities and Exchange Commission, including without limitation the factors discussed under the caption "Risk Factors" in Genzyme's Quarterly Report on Form 10-Q for the fiscal quarter ended March 31, 2007. We caution investors not to place undue reliance on the forward-looking statements contained in this press release. These statements speak only as of the date of this press release, and we undertake no obligation to update or revise the statements.
Genzyme and Synvisc are registered trademarks and Synvisc-One is a trademark of Genzyme Corporation. All rights reserved.
Genzyme's press releases and other company information are available at www.genzyme.com and by calling Genzyme's investor information line at 1-800- 905-4369 within the United States or 1-703-797-1866 outside the United States.
CONTACT: Media, Maria Cantor, +1-617-768-6690, or Investors, Carol Miceli,+1-617-768-6602, both of Genzyme Corp.
Web site: http://www.genzyme.com/
Ticker Symbol: (NASDAQ-NMS:GENZ)
Good luck to you...
LaurieShay
28 May 2011
Hey sippy,
Severe pain needs to be addressed by the doctor. If the prescribing doctor won't see you then I would get another opinion asap. The Synvisc is suppose to be injected into the knee joint. You really need to be seen by a doctor for this.
Best wishes,
Laurie
Related topics
synvisc, pain, injection, synvisc-one, knee
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