How long before Trazodone works?

According to my pharmacist, it can take up to 2-3 weeks before trazodone kicks in. It has to build up in your system to work. It took me 5 days on 100mg before it began to work and although I've been on it for a week and a half, when I wake up in the middle of the night, I can't get back to sleep without some other assistance. Pharmacist says this may change in the next few weeks. Don't give up. Everyone's reaction and reaction times are different. For some people, when it works, it works within 15 to 30 minutes. For me, it takes an hour. I think it is a good sign that it makes you sleepy. I hope you can hang in there and see if it will work with time.

my dr recently prescribed me trazodone (100mg) to take every night at bedtime, however she also prescribed me xanax (1mg) to take in addition to it (as needed). your situation sounds similar to mine, you're physically tired but your mind wont shut off and thats where the xanax becomes helpful. i would discuss.this option with your dr. good luck :)

shes right should of worked first time cosult a doc

Hi schnookylu--- My experience with trazodone for the treatment of insomnia is that it should do the job the first night. It has a short window of time for it to be effective for sleep. You should take it and go directly to bed, if it is not working at 100mg dose, you should talk to your Doc. For insomnia it does not take days or weeks to work. It should work immediately- Good luck